Patents Assigned to University
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Patent number: 10470211Abstract: The present disclosure relates to a pre-5th-generation (5G) or 5G communication system to be provided for supporting higher data rates beyond 4th-generation (4G) communication system such as long term evolution (LTE). An apparatus of a base station in a wireless communication system is provided. The apparatus includes at least one processor configured to determine a length of a channel occupancy period and a length of a contention period with respect to a band shared with other system, and a transceiver configured to, when detecting no signal of the other system until a time indicated by a back-off value in the contention period, transmit a signal over the band. A method of a base station in a wireless communication system is provided.Type: GrantFiled: April 12, 2016Date of Patent: November 5, 2019Assignees: Samsung Electronics Co., Ltd., Korea University Research and Business FoundationInventors: Chung Gu Kang, Chung Kee Kim, Chan Seok Yang
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Composition comprising diacid derivatives and their use in the treatment of collagenic eye disorders
Patent number: 10463610Abstract: The present invention relates to novel pharmaceutical formulations. More specifically, the present invention relates to novel pharmaceutical formulations that are suitable for intraocular administration. The present invention also relates to the use of these formulations for the treatment of collagenic eye disorder such as, for example, the treatment of keratoconus.Type: GrantFiled: November 3, 2016Date of Patent: November 5, 2019Assignee: The University of LiverpoolInventors: Rachel L. Williams, Colin E. Willoughby -
Patent number: 10464944Abstract: The present invention provides tricyclic compounds, pharmaceutically acceptable salts, solvates, or hydrates thereof, having antimitotic activity, anti-multidrug resistance activity, for example P-glycoprotein inhibition, and antitumor activity, and which inhibit paclitaxel sensitive and resistant tumor cells. Also provided are methods of utilizing these compounds for treating tumor cells and inhibiting mitosis of cancerous cells.Type: GrantFiled: May 31, 2018Date of Patent: November 5, 2019Assignee: Duquesne University of the Holy SpiritInventor: Aleem Gangjee
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Patent number: 10465242Abstract: Systems, devices, and methods for capturing single source-specific biological material from a multi-source aggregate of biological material are disclosed and discussed. A capture system is generated using reversible chain-blocking to make capture substrates having substrate-linked populations of capture molecules specific for molecules of interest. Incubating such capture substrates in the presence of only a single source of biological material facilitates the association of molecules of interest from the same source. Capture substrate-specific barcode sequences coupled to the capture molecules allow multisource aggregate processing and subsequent grouping to retain the source-specific information following downstream processing.Type: GrantFiled: July 14, 2017Date of Patent: November 5, 2019Assignee: University of Utah Research FoundationInventors: John Phillips, William M. Hanson, Jennifer M. Heemstra
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Patent number: 10468203Abstract: Systems and methods are described for an edible capacitive power source such as a supercapacitor device. The capacitive power source includes an anode electrode, an anode current collector, a cathode electrode, and a cathode current collector, arranged in layers with a separator layer positioned between the anode electrode and the cathode electrode forming a symmetrical electrical double-layer capacitor. The anode electrode, the anode current collector, the cathode electrode, the cathode current collector, and the separator layer are all constructed of non-toxic, edible materials. The packaging material, the conductive anode tab, and the conductive cathode tab are all also constructed of non-toxic, edible materials forming a completely edible capacitive power source package.Type: GrantFiled: August 25, 2016Date of Patent: November 5, 2019Assignee: Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Hanqing Jiang, Prithwish Chatterjee, Wenwen Xu, Xu Wang
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Patent number: 10465043Abstract: Various embodiments disclosed relate to electrochemical isomerization of muconic acid. In various embodiments, the present invention provides a method to prepare trans,trans-muconic acid. The method can include passing current through a catalytic cathode in a reactor including an aqueous acidic solution including cis,trans-muconic acid, a supporting electrolyte, and an anode, so as to isomerize the cis,trans-muconic acid to yield a product including trans trans-muconic acid.Type: GrantFiled: November 10, 2016Date of Patent: November 5, 2019Assignee: Iowa State University Research FoundationInventors: Jean-Philippe Tessonnier, John Edward Matthiesen, Toni Pfennig, Brent Shanks, Jack M. Carraher
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Patent number: 10463626Abstract: A dry composition, comprising three-dimensional porous microparticles, wherein the microparticles comprise: (i) an active substance (eg a poorly water soluble drug), (ii) polymeric nanoparticles such as those composed of a biocompatible and/or biodegradable polymer (eg a PLGA polymer) (iii) lipid droplets (eg droplets of a medium chain triglyceride (MCT)), (iv) a nanoparticle stabilizing agent such as PVA or DMAB, and optionally, (v) a cryoprotectant (eg mannitol); wherein said active substance is carried by said nanoparticles and/or lipid droplets. The composition of the present invention may be formulated into, for example, a medicament for the treatment and/or prevention of various diseases or disorders (eg human or veterinary therapeutics). The average diameter of the individual microparticles of the composition, may be in the order of 2.5-3.5 ?m which are particularly suitable for administration to the lung.Type: GrantFiled: March 11, 2016Date of Patent: November 5, 2019Assignee: University of South AustraliaInventors: Clive Allan Prestidge, Paul Matthew Joyce
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Patent number: 10464983Abstract: Variant peptides of calcitonin gene-related peptide alpha (?CGRP), calcitonin gene-related peptide beta (?CGRP), and adrenomedullin (AM) are disclosed, wherein the variant peptides have high binding affinity and agonistic or antagonistic activity for at least one receptor complex of CLR:RAMP1, CLR:RAMP2, and CLR:RAMP3. Also disclosed are methods of use of the variant peptides in therapeutic treatments.Type: GrantFiled: May 13, 2016Date of Patent: November 5, 2019Assignee: The Board of Regents of the University of OklahomaInventor: Augen A. Pioszak
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Patent number: 10466082Abstract: A flow meter (1) comprising a sampling tube (3) through which fluid may flow and a sensor arrangement (9, 25, 27, 39, 41, 43, 44, 45, 46, 47), wherein the sampling tube (3) comprises a first hollow section (51, 53) having a first internal cross-sectional area (A1) and a second hollow section (55, 57) having a second internal cross-sectional area (A2) being less than the first internal cross-sectional area (A1); and the sensor arrangement (9, 25, 27, 39, 41, 43, 44, 45, 46, 47), is for measuring the difference between stagnation and static pressures (P01, P02, P1, P2) within the second hollow section (55, 57).Type: GrantFiled: December 21, 2015Date of Patent: November 5, 2019Assignee: University of SurreyInventors: David Birch, Paul Nathan, Praveen Rampersad
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Patent number: 10466416Abstract: Multilevel leaky-mode optical elements, including reflectors, polarizers, and beamsplitters. Some of the elements have a plurality of spatially modulated periodic layers coupled to a substrate. For infrared applications, the optical elements may have a bandwidth larger than 600 nanometers.Type: GrantFiled: October 16, 2017Date of Patent: November 5, 2019Assignee: Board of Regents, The University of Texas SystemInventors: Robert Magnusson, Mehrdad Shokooh-Saremi
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Patent number: 10466036Abstract: An imager utilizes a division of focal plane polarization and color camera to measure motion, depth and orientation of objects in a scene in real-time. In various examples, structured light, polarization-controlled discrete reflectors, and/or spatially varying discrete light sources are used to provide light of controlled polarization and color from an object in a scene to a camera. The camera utilizes a pixelated optical filter with a pattern of varying polarization filters across the pixel array, and optionally an integrated color filter pattern. Light measurements are processed to determine polarization state of light received from the object, whence orientation, position, and/or other properties of the object are determined. Systems are operable with a single camera. Applications include virtual reality, gaming, robotics, autonomous vehicles, tele-surgery, industrial automation, 3-D scanning, surveillance, and remote interaction.Type: GrantFiled: October 5, 2017Date of Patent: November 5, 2019Assignee: Arizona Board of Regents on Behalf of the University of ArizonaInventor: Stanley Pau
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Patent number: 10465650Abstract: An energy conversion device includes a container body configured to hold a liquid; a housing affixed above the container body by a handler connected to a surface of the container body, wherein a primary roller is configured to rotate at a first end of the housing and a free roller is configured to rotate at a second end of the housing; a piston attached at a first end to an outer perimeter of the primary roller; an inflatable balloon attached to a second end of the piston within the container body, wherein vertical movement of the piston causes the primary roller to rotate; an air chamber configured to supply air to a lower opening in the inflatable balloon via a balloon valve; and an interconnect located on a side of the free roller configured for connection to one of an energy-driven device or a turbine generator.Type: GrantFiled: April 5, 2017Date of Patent: November 5, 2019Assignee: Imam Abdulrahman Bin Faisal UniversityInventor: Mahmoud Mohamed Majzoub Mohamed
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Patent number: 10466194Abstract: One embodiment is a biochip having an array of biosensors for quantitative determination of protein-protein and/or antibody-antigen interactions. The array comprises at least two biosensors formed on a substrate. The biosensors can be used to detect either the same or different analytes. The biosensors may be acoustical transducers operated in the thickness shear mode of vibration, wherein the density, viscosity, and elasticity at the sensor interface can be ascertained. Additionally, a series of fluidic channels are etched to the same depth as the biosensors. The fluidic channels serve to efficiently deliver the sample to the biosensors. One or more biochips can be housed within an enclosure.Type: GrantFiled: February 11, 2016Date of Patent: November 5, 2019Assignee: Drexel UniversityInventors: Johann deSa, Qiliang Zhang, Ryszard Lec, Ertan Ergezen
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Patent number: 10465218Abstract: The invention discloses a method for increasing the yield of L-arginine by knocking out flavin reductases, and belongs to the technical field of amino acid production by microbial fermentation. Genes frd1 and frd2 for encoding hypothetic NADPH-dependent FMN reductase in Corynebacterium crenatum SDNN403 are over-expressed in E. coli BL21 and are purified to form target proteins Frd181 and Frd188, and functions of the target proteins are identified to obtain a result showing that the proteins Frd181 and Frd188 both are NAD(P)H-dependent flavin reductases producing H2O2. By taking a genome of the Corynebacterium crenatum SDNN403 as a template, frd1 and frd2 gene deletion fragments are obtained by overlap extension PCR; connecting pK18mobsacB to obtain knockout plasmids pK18mobsacB-?frd1 and pK18mobsacB-?frd2; carrying out electric shock to transform the Corynebacterium crenatum SDNN403; and carrying out secondary screening to obtain recombinant strains 403?frd1 and 403?frd2.Type: GrantFiled: July 29, 2016Date of Patent: November 5, 2019Assignee: Jiangnan UniversityInventors: Zhiming Rao, Zaiwei Man, Meijuan Xu, Taowei Yang, Xian Zhang
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Patent number: 10464019Abstract: The present invention relates to a nickel-based catalyst for oxidizing carbon monoxide, which is prepared by forming nickel oxide on the surface of a mesoporous support by one or more cycles of atomic layer deposition, and a use thereof. The nickel-based catalyst for oxidizing carbon monoxide according to the present invention is stable at high temperatures because the size of the nickel oxide particles can be restricted to nanometer scales even at high-temperature conditions. In addition, the nickel-based catalyst exhibits catalytic reactivity for oxidation of carbon monoxide even at room temperatures. Additionally, the catalytic activity, which has been deactivated after conducting the catalytic reaction, can be regenerated through annealing and increased gradually through repeated annealing.Type: GrantFiled: August 18, 2015Date of Patent: November 5, 2019Assignee: Research & Business Foundation Sungkyunkwan UniversityInventors: Young Dok Kim, Dae Han Kim, Ju Ha Lee, Myung Geun Jeong, Sang Wook Han
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Patent number: 10467556Abstract: Certain examples provide systems and methods to identify placement for an electric charging station infrastructure. Certain examples provide systems and methods to generate a deployment plan for one or more electric vehicle charging stations. An example method includes gathering data for a specified geographic area and forecasting a demand for electric vehicles for the specified area. The example method includes modeling driving patterns in the specified area using available data and improving a charging infrastructure model based on the driving pattern and demand forecast information for the specified area. The example method includes generating and providing a recommendation regarding an electric vehicle charging infrastructure and deployment strategy for the specified area based on the improved charging infrastructure model.Type: GrantFiled: February 9, 2012Date of Patent: November 5, 2019Assignee: Northwestern UniversityInventor: Diego Klabjan
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Patent number: 10468703Abstract: The present invention relates to a redox fuel cell comprising an anode and a cathode separated by an ion selective polymer electrolyte membrane; means for supplying a fuel to the anode region of the cell; means for supplying an oxidant to the cathode region of the cell; means for providing an electrical circuit between the anode and the cathode; a non-volatile catholyte solution flowing in fluid communication with the cathode, the catholyte solution comprising a polyoxometallate redox couple being at least partially reduced at the cathode in operation of the cell, and at least partially re-generated by reaction with the oxidant in a regeneration zone after such reduction at the cathode, the catholyte solution further comprising one or more vanadium species that result from the speciation of the polyoxometallate at an elevated temperature and/or pressure, wherein the polyoxometallate is represented by the formula: Xa[ZbMcOd] wherein X is selected from hydrogen, alkali metals, alkaline earth metals, ammonium,Type: GrantFiled: June 25, 2014Date of Patent: November 5, 2019Assignee: University of ChesterInventors: David Lee Rochester, Matthew Alexander Herbert, Andrew Martin Creeth
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Patent number: 10463669Abstract: The present application relates to a pharmaceutical composition containing compound 5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]-4-3H)-quinazolinone, and a pharmaceutically acceptable salt thereof for preventing and treating liver cancer, and the composition of the present application inhibits ROS-PI3K-AKT-TERT signal transduction, and thus can be favorably used in the treatment of a liver cell cancer, in which a protein involved in the signal transduction is overexpressed, especially, advanced liver cell cancer.Type: GrantFiled: February 14, 2017Date of Patent: November 5, 2019Assignee: Seoul National University R&DB FoundationInventors: Guhung Jung, Eunkyong Ko, Yoon Jun Kim
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Patent number: 10468965Abstract: Disclosed are multi-stage multilevel DC-DC step-down converters. Stages may include three or four switches, and switches of each stage are operated at selected duty cycles such that each stage reduces an input voltage by one-half and voltage stress on switches is reduced. In some embodiments only a single output inductor is used in an LC filter, and the inductor may be very small as compared with a conventional Buck converter. Thus, embodiments provide DC-DC step-down converters with high power density and efficiency.Type: GrantFiled: July 6, 2017Date of Patent: November 5, 2019Assignee: Queen's University at KingstonInventors: Tianshu Liu, Yan-Fei Liu
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Patent number: 10465238Abstract: Methods and reagents for performing digital PCR for detection and quantification of mutant alleles and copy number variation are disclosed. In particular, the invention relates to methods using a nonspecific DNA-binding dye, which produces a fluorescent signal that increases in intensity according to the number of base-pairs present in the PCR amplicon product. The method utilizes mutant-specific and wild-type-specific primers having non-complementary “tail” sequences of different lengths. Accordingly, the amplicons for the wild-type and mutant alleles differ in length and can be distinguished based on the difference in the intensities of their fluorescent signals. The methods of the invention can be used to detect rare genetic events, including single nucleotide mutations, alterations of copy number, and deletions or insertions of nucleotides.Type: GrantFiled: December 16, 2014Date of Patent: November 5, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Hanlee P. Ji, Billy Tsz Cheong Lau, Laura Miotke