Abstract: The present invention includes a device and method for a self-expanding framework device adapted to facilitate the deployment of an extra-cardiac device. The device includes a deployment tube and a self-expanding wire framework having a structure that results in the self-expanding wire framework circumferential flaring motion and bending outwardly to advance around the heart.

Abstract: Provided are multiply functional telodendrimers. The telodendrimers can be used for combination drug delivery. The telodendrimers may have one or more crosslinking groups (e.g., reversible photocrosslinking groups). The telodendrimers can aggregate to form nanocarriers. Cargo such as combinations of drugs, imaging probes, and other materials may be sequestered in the core of the aggregates via non-covalent or covalent interactions with the telodendrimers. Such nanocarriers may be used in drug delivery applications and imaging applications.

Abstract: Combining the functionality of sleep transistors with logic devices in power-gating circuits by utilizing fully depleted silicon-on-insulator (FDSOI) transistors. In an embodiment, a back gate of a FDSOI transistor controls the threshold voltage to eliminate the need for standalone sleep transistors.

Abstract: Provided herein are synthetic peptides or synthetic fragments thereof based on a Histatin-5 peptide, for example with a sequence DSHAKRHHGYKRKFHEKHHSHRGY (SEQ ID NO: 1). The synthetic peptides or synthetic fragments have at least one substituted amino acid that is arginine and/or leucine to increase resistance to proteolytic degradation by a microbe, such as a fungus. The synthetic peptides or synthetic fragments thereof may be contained in a hydrogel. Also provided are methods for treating or preventing a pathophysiological condition via topical administration of the synthetic peptide or fragments. The pathophysiological condition may be a fungal or bacterial infection including associated inflammation or a chronic condition.

Abstract: Methods and compositions are described for use in encouraging angiogenesis and skin healing as may be utilized in wound treatment as well as in encouragement of angiogenesis in disease. Compositions include an effective amount of a natural pimarane diterpenoid extract of Hymenocrater elegans, or a derivative, analogue, or homolog thereof. Compounds based upon this natural extract have been found to be highly effective in vascular formation and skin closure while exhibiting low toxicity.

Abstract: In one embodiment, a propulsion system includes roaming vehicles including a reaction plate installed on a bottom of each of the roaming vehicles, a surface stator matrix installed with a running surface for the roaming vehicles and including single sided linear induction motors (SSLIMs). Each of the SSLIMs include two windings installed orthogonally to one another. The propulsion system also includes motor drives configured to electrically couple to the SSLIMs via a switching panel, and a control system configured to receive information related to the roaming vehicles, receive a desired motion profile for the roaming vehicles across the surface stator matrix, determine which of the SSLIMs to activate and a performance of the SSLIMs based on the desired motion profile, the information, or some combination thereof, and send control signals to the motor drives to control the SSLIMs to produce the motion profile.

Abstract: Disclosed herein are FGF23 c-tail fusion proteins, pharmaceutical compositions comprising the FGF23 c-tail fusion proteins, and methods of treatment using the FGF23 c-tail fusion proteins. This application discloses fusion proteins comprising a FGF-23 c-tail protein fused to a heterologous amino acid sequence, wherein said fusion protein modulates serum phosphate levels but does not substantially modulate serum 1, 25 VitD levels. In some embodiments, the FGF-23 c-tail protein is fused to the heterologous amino acid sequence via a linker. This invention also encompasses vectors comprising the nucleic acids disclosed herein, and a host cell comprising the vector or polynucleotides encoding the proteins of the invention.

Abstract: A composite material can include a gel and at least one nanostructure disposed within the gel. A method for healing a soft tissue defect can include applying a composite material to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a composite material for use in healing soft tissue defects can include providing a gel and disposing nanofibers within the gel.

Abstract: Disclosed herein are a method and device for cloaking an acoustic wave. A method for cloaking an acoustic wave according to an embodiment of the present invention includes: obtaining a target characteristic of a meta-material based on a correlation between an acoustic propagation mathematical model predetermined for the propagation of an acoustic wave and an electromagnetic wave mathematical model predetermined for an electromagnetic wave; arranging scattering media having a predetermined media density to have spatial periodicity so that the obtained target characteristic is achieved; and blocking a region including a target object from an acoustic wave by disposing the meta-material including the scattering media arranged to have spatial periodicity, to surround the region.

Abstract: A sensing method is based on using a special fiberoptic probe for detection of acoustic/ultrasound pressure in an immersion medium. The developed system is highly sensitive in detecting ultrasound waves up to 100 MHz, for imaging of micro structures and more. For applications up to 100 MHz, without spatial averaging corrections, the probe tip is modified by reducing the fiber diameter to 7 um or less. Also, to maximize acousto-optic interaction, the probe tip, not just its end face, may be coated with a thin layer of metallic material. This thin film coating satisfies partial transparency of the metallic coating. The coating thickness may range from 2 nm to 10 nm or others depending on the type of the coating material. The probe detects the pressure of acoustic and/or ultrasound waves propagating within an immersion medium, whenever the probe tip is immersed inside the medium, and having a reasonable immersion contact surface.

Abstract: The present disclosure relates to implementations of physically unclonable functions (PUFs) for cryptographic and authentication purposes. Specifically, the disclosure describes implementations of machine learning engines (MLEs) in conjunction with PUFs generating outputs having multiple states.

Abstract: A method for controlling the operation of a plurality of consumer electronic devices by displaying a plurality of broadcast channel identifiers each corresponding to a broadcast channel in a display of a controlling device adapted to command at least channel tuning operations of the plurality of consumer electronic devices. Input is accepted into the controlling device that functions to designate one of the plurality of broadcast channel identifiers and the controlling device uses the designation of the one of the plurality of broadcast channel identifiers to cause a transmission of a wireless signal from the controlling device to a one of the plurality of consumer electronic devices to thereby cause the one of the plurality of consumer electronic devices to tune to the broadcast channel corresponding to the designated one of the plurality of broadcast channel identifiers.

Abstract: A method and kit for detecting a target nucleic acid is provided wherein combining an amplified nucleic acid with a particle such as a paramagnetic bead form a flocculated complex which can be detected by visual inspection. The volume of nucleic acid sample that can be detected is as low as a few microlitres. The method can be applied to in-the-field or point-of-care diagnosis for a rapid determination of the presence or absence of the target nucleic acid. The methylation status of a target nucleic acid can also be determined. The method and lit may have general applicability to detecting diseases in plants and animals, environmental testing and testing for contamination of foods and other edible products.

Abstract: The present invention relates to methods for enhancing at least one growth parameter of a leguminous plant via co-inoculation of a leguminous plant with at least one rhizobial microorganism together with at least one actinobacterial microorganism. In further aspects, the present invention also relates to leguminous plants co-inoculated with at least one rhizobial microorganism together with at least one actinobacterial microorganism, as well as specific actinobacterial strains and inoculant compositions which are useful in accordance with the present invention.

Abstract: A method of improving diagnostic and functional imaging is provided by obtaining at least two input images of a subject, using a medical imager, where each input image includes a different contrast, generating a plurality of copies of the input images using non-local mean (NLM) filtering, using an appropriately programmed computer, where each input image copy of the subject includes different spatial characteristics, obtaining at least one reference image of the subject, using the medical imager, where the reference image includes imaging characteristics that are different form the input images of the subject, training a deep network model, using data augmentation on the appropriately programmed computer, to adaptively tune model parameters to approximate the reference image from an initial set of the input and reference images, with the goal of outputting an improved quality image of other sets of low SNR low resolution images, for analysis by a physician.

Abstract: A three-dimensional electronic, biological, chemical, thermal management, and/or electromechanical apparatus can be configured by depositing one or more layers of a three-dimensional structure on a substrate. Such a three-dimensional structure can include one or more internal cavities using an additive manufacturing system enhanced with a range of secondary embedding processes. The three-dimensional structure can be further configured with structural integrated metal objects spanning the internal cavities (possibly filled with air or even evacuated) of the three-dimensional structure for enhanced electromagnetic properties.

Abstract: In one embodiment, a dilute wastewater treatment system includes a separation subsystem configured to receive dilute wastewater and separate it into a product stream containing a low concentration of organic material and a reject stream containing a high concentration of organic material, and a conversion subsystem configured to receive the reject stream from the separation subsystem and anaerobically treat the reject stream to break down the organic material and separate it from water within the reject stream.

Abstract: The invention provides antibodies or an antigen-binding portion thereof, which recognize the human Frizzled 7 receptor. Further, the invention provides methods of using these antibodies for the treatment cancer in a subject.

Abstract: In some embodiments, the compositions and methods relate to compounds isolated from plants in the Salviniaceae family, pharmaceutical compositions comprising the same, and methods of using the same.

Abstract: Provided is a method and apparatus of dynamic loading file extraction. The method for extracting a specific dynamic generated file of an application running in an Android container environment includes conducting first analysis to identify if a file extension that is stored in the Android container corresponds to a preset critical extension, to extract a file with the critical extension, and conducting second analysis to identify a deleted file standing for a file deleted after stored in the Android container, and running the application again and extracting the deleted file based on a result of the second analysis.