Abstract: There are provided methods, and devices for assaying for a binding interaction between a protein, such as a monoclonal antibody, produced by a cell, and a biomolecule. The method may include retaining the cell within a chamber having an aperture; exposing the protein produced by the cell to a capture substrate, wherein the capture substrate is in fluid communication with the protein produced by the cell and wherein the capture substrate is operable to bind the protein produced by the cell; flowing a fluid volume comprising the biomolecule through the chamber via said aperture, wherein the fluid volume is in fluid communication with the capture substrate; and determining a binding interaction between the protein produced by the cell and the biomolecule.

Abstract: The present invention relates to a method and apparatus for encoding/decoding a video, the method being applied with a method of using video padding and removing the padded area after decoding in order to effectively encode the video in a video compression technology for a high-definition security camera.

Abstract: Chimeric polyvalent recombinant proteins for use as vaccines and diagnostics for Lyme disease (e.g. in canines and humans) are provided. The chimeric proteins comprise epitopes of the loop 5 region and/or the alpha helix 5 region of outer surface protein C (OspC) types and/or OspE types. The OspC types may be associated with mammalian Borrelia infections.

Abstract: Transformed plants are disclosed with enhanced resistance to abiotic stresses, such as salt stress, water stress, or temperature stress. Also disclosed are vectors useful for making such transformed plants, and methods of transforming plants to enhance resistance to abiotic stresses, such as salt stress, water stress, or temperature stress. For example, the Spartina alterniflora ADF gene SaADF2 enhances resistance when transformed into rice Oryza sativa. Transgenic rice plants that expressed higher levels of Spartina ADF were more resistant to salt, drought, and cold. There was improved growth, higher photosynthesis, and increased grain yield as compared to wild-type (WT) rice.

Abstract: The application provides new compositions and methods for stimulating the production of natural killer (NK) cells in a subject. NK cells can be selectively expanded with a combination of stimulating ligands. Methods and compositions for the administration of stimulatory ligands modified to self-insert into tumor cells, thereby stimulating an increase in the number of NK cells in proximity to a tumor, are also described.

Abstract: A 3D printing system may print a desired 3D object. A fusible powder may fuse when subjected to a fusing condition. A deposition system may deposit portions of the fusible powder on a substrate. A fusing system may apply the fusing condition to the deposited fusible powder. Inhibitor material may not fuse when subjected to the fusing condition. An insertion system may insert a portion of the inhibitor material between portions of the deposited fusible powder after having been deposited by the deposition system, but before being fused by the fusing system, so as to form a boundary that defines at least a portion of a surface of the desired 3D object.

Abstract: Three-layer full-color dynamic electronic paper, comprising a substrate, a controller, a first EWOD display layer, a second EWOD display layer and a third EWOD display layer, wherein each of the first, second and third EWOD display layer is comprised of an upper transparent electrode plate, a hydrophobic insulating layer, pixel walls, colored ink, colorless liquid, a lower transparent electrode plate, an encapsulation adhesive, and a driving chip connected to the upper transparent electrode plate and the lower transparent electrode plate respectively; the lower transparent electrode plate of the third EWOD display layer is located above the substrate; the colored ink filled in the first, second and third EWOD display layer is cyan ink, magenta ink and yellow ink, respectively; and, the controller controls voltage waveforms of the three driving chips according to a subtractive color mixture principle of three primary colors for printing, so as to realize full-color displaying.

Abstract: A three-dimensional microfluidic platform including a substrate and a heterogeneous structure is provided. The heterogeneous structure located on the substrate includes prepolymer pattern, cured products, or a combination of at least one prepolymer patterns and at least one cured products, where the material characteristics of the cured products are different from each other, and the material characteristics of the prepolymer patterns are different from each other.

Abstract: A wearable device includes: at least one compliant region adapted and configured to be placed over a joint of a subject and at least two flexible but less compliant regions coupled to opposite ends of the compliant region. The device provides a wearable robotic device including a wearable and at least one actuator adapted and configured to move the flexible but less compliant regions relative to each other.

Abstract: The present invention involves identification of inhibitors of herpesvirus nucleic acid metabolism. Also provided are methods of treatment using agents identified.

Abstract: The present invention discloses a maltooligosyl trehalose trehalohydrolase (MTHase) mutant and application thereof, belonging to the technical fields of gene engineering and enzyme engineering. The present invention provides a series of MTHase mutants to prepare trehalose, having a better effect. Further, the MTHase mutant is expressed in Escherichia coli BL21 (DE3) and the enzyme is optimized by fermentation, which can significantly increase the yield of enzymes.

Abstract: This disclosure relates to recombinant proteins comprising a GM-CSF sequence and an interleukin sequence and nucleic acids related thereto. In certain embodiments, the disclosure relates to recombinant proteins comprises N-terminal sequences that are the result of improved production techniques and uses for treating or preventing autoimmune diseases such as multiple sclerosis and cancer.

Abstract: An oil-in-water emulsion comprises an emulsifier which is a non-gelled branched polymer (e.g. a branched vinyl polymer), wherein the ends of at least some of the chains of said polymer terminate in an alkyl chain of 5 carbon atoms or more, and wherein the oil-in-water emulsion takes the form of particles having a z-average diameter of no greater than about 1000 nm. This is useful in, for example, facilitating the carrying of hydrophobic materials within aqueous systems, to enhance oral drug delivery. The oil-in-water emulsion may be prepared by mixing an oil phase with an aqueous phase in the presence of an emulsifier, wherein said emulsifier is a non-gelled branched polymer, wherein the ends of at least some of the chains of said polymer terminate in an alkyl chain of 5 carbon atoms or more, and wherein the oil-in-water emulsion takes the form of particles having a z-average diameter of no greater than about 1000 nm.

Abstract: There is provided a recombinant bacterium comprising at least one overexpressed acyl-ACP thioesterase gene, and wherein at least one gene from the tricarboxylic acid cycle or glycolysis or both is inactivated. There is also provided a method for producing fatty acids, said method comprising culturing bacteria comprising at least one overexpressed acyl-ACP thioesterase gene in a growth medium in a container having walls; allowing said bacteria to secrete fatty acids; and collecting said fatty acids. Acid supplementation is also shown to increase productivity.

Abstract: A three-dimensional (three dimensional) segmentation method with intensity-based Doppler variance (IBDV) based on swept-source OCT. The automatic three dimensional segmentation method is used to obtain seven surfaces of intra-retinal layers. The microvascular network of the retina, which is acquired by the IBDV method, can be divided into six layers. The microvascular network of the six individual layers are visualized, and the morphology and contrast images can be improved by using the segmentation method. This method has potential for earlier diagnosis and precise monitoring in retinal vascular diseases. Each tomographic image is composed of eight repeat scans at the same position, which achieves a high time difference to improve the sensitivity of the angiographic method. A subpixel registration algorithm is used to reduce the eye movement. The GPU was used to accelerate the data processing to achieve real-time preview of the acquired data.

Abstract: An optical device includes a first waveguide having a longitudinal axis and a first end facet inclined at a non-normal angle to the longitudinal axis, and a second waveguide, which has a second end facet and is fixed with the second end facet in proximity to and parallel with the first end facet. An actuator is coupled to move the first end facet of the first waveguide in a direction transverse to the longitudinal axis between a first position in which a distance between the first and second end facets is less than 25 nm, and a second position in which the distance between the first and second end facets is greater than 300 nm.

Abstract: An identifier for a conduit includes a first tag having a body with a first aperture formed therein for receiving the conduit and a first identifying feature, and a second tag having a body with a second aperture formed therein for receiving the conduit and a second identifying feature that matches the first identifying feature. The first tag is attached to the conduit adjacent one end, the second tag is attached to the conduit adjacent another end, and the ends are identified as ends of the same conduit by the matching first and second identifying features.

Abstract: An ultrasound generator having a signal generator; and to generate a pulsed drive signal from a modulating signal, the pulsed drive signal having at least a zero output level, a positive output level and a negative output level. The position and width of pulses are defined by at least first and second switching angles per half cycle of the modulating signal. In part of the range of the modulating signal one switching angle increases while the other switching angle decreases simultaneously such that the fundamental frequency of the pulsed drive signal increases or decreases with the modulating signal and such that a selected harmonic component of the generated pulsed drive signal is maintained below a first threshold. A transducer is arranged to generate ultrasound in response to the pulsed drive signal.

Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone. This neural fulcrum zone may be identified by monitoring a patient's response to incrementally increased intensity settings at a first frequency. If the incremental intensity increases do not result in the identification of the neural fulcrum zone, the frequency may be changed to provide finer resolution identification of the neural fulcrum zone.

Abstract: An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.