Abstract: Methods to access 2-aryl chromene compounds via an asymmetric catalytic process.

Abstract: A vertical-mode tunnel field-effect transistor (TFET) is provided with an oxide region that may be laterally positioned relative to a source region. The oxide region operates to reduce a tunneling effect in a tunnel region underlying a drain region, during an OFF-state of the TFET. The reduction in tunneling effect results in a reduction or elimination of a flow of OFF-state leakage current between the source region and the drain region. The TFET may have components made from group III-V compound materials.

Abstract: Embodiments of solid-state stress sensors are presented herein. A sensor system may include a substrate, a first layer of sensing material disposed on a first surface of the substrate, and at least three electrodes forming a first and second electrode pair. The at least three electrodes may include a first electrode, a second electrode, and a third electrode. The first electrode may be disposed in a first plane and the second electrode and the third electrode may be disposed in a second plane, the first and second planes associated with a first direction parallel to the first surface. The first and second electrodes may be at least partially offset in the first direction. The first and third electrodes may be at least partially offset in the first direction. The sensor system may be configured to generate an output signal in response to a shear stress within the sensing material.

Abstract: The present disclosure relates to a novel small molecule TLR2 antagonist, and particularly, to 19 novel TLR2 antagonists, a pharmaceutical composition, including the antagonists, for preventing or treating inflammatory diseases, and a TLR4 regulator. The novel TLR2 antagonists according to the present disclosure can be effectively used as a preparation for oral administration by having low molecular weight and high oral bioavailability, and can be useful in pharmaceutical compositions for preventing or treating inflammatory diseases since the secretion of IL-8 is effectively inhibited and in vivo cytotoxicity is not induced. In addition, the novel TLR2 antagonists according to the present disclosure can be used as a TLR4 regulator.

Abstract: A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: wherein X is a divalent linking moiety; and R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.

Abstract: A floating gate based sensor apparatus includes at least two separate electrical bias components with respect to a floating gate based sensor surface within the floating gate based sensor apparatus. By including the at least two electrical bias components, the floating gate based sensor apparatus provides enhanced capabilities for biomaterial and non-biomaterial detection and manipulation while using the floating gate based sensor apparatus.

Abstract: The invention discloses an electric vehicle charging pile control system and method considering grid frequency safety. The electric vehicle charging pile control system comprises a grid single-phase power input port, a voltage transformer, an AD conversion chip, a first data processor and a second data processor connected successively; the first data processor is further connected with a data real-time display device and a GPS/Beidou signal receiver respectively; the second data processor communicates with an electric vehicle charging pile and an electric vehicle battery pack respectively; and the second data processor is further connected with a man-machine interaction device.

Abstract: Example apparatuses and methods relating to antennas are provided. An example apparatus in the form of an antenna assembly includes a first conductor formed into a first helical structure wound around a central axis and a second conductor formed into a second helical structure wound around the central axis. The first helical structure may have a first coil sense and the second helical structure may have second coil sense that is opposite the first coil sense. The first conductor may have a first conductor proximal end and a first conductor distal end and the second conductor may have a second conductor proximal end and a second conductor distal end. The first conductor distal end may be adjacent the second conductor proximal end. The antenna assembly may further include first, second, and third ground planes with one disposed at each end of the conductors and one disposed between the conductors.

Abstract: The present application relates to a sensing method that is carried out using an electrode that comprises an electrode substrate functionalized with sensing elements. The method involves conducting electrochemical impedance spectroscopy at a plurality of applied voltages and then integrating measurement data as a function of voltage. Also provided is an apparatus for carrying out the sensing method. The method and apparatus are suitable for a broad range of sensing applications, including the detection of diagnostic biomarkers, drug screening, development of glycoarray systems and the sensing of environmental parameters such as light intensity, temperature and humidity.

Abstract: This document describes techniques and devices for type-agnostic radio frequency (RF) signal representations. These techniques and devices enable use of multiple different types of radar systems and fields through type-agnostic RF signal representations. By so doing, recognition and application-layer analysis can be independent of various radar parameters that differ between different radar systems and fields.

Abstract: A renewable energy-based hybrid bi-directionally interactive DC traction power supply system includes two traction substations. Each substation includes transformers, rectifiers, bidirectional AC-DC converters, a DC bus, a catenary, a steel rail and a section post. A DC bus between two adjacent traction substations is provided with a DC renewable energy system constructed by an electric vehicle charging-discharging system, a distributed generation and more than one low voltage DC microgrid. The DC renewable energy system is connected to the DC bus between two adjacent traction substations through a high voltage DC bus, thus a DC circular microgrid being formed in a power supply section post. The electric vehicle charging-discharging system is formed by more than one bidirectional DC-DC charging-discharging equipments which are intended for in connection with the power batteries of the electric vehicle.

Abstract: A hover controlling device includes a sensing unit and a hover control unit. The sensing unit includes a plurality of first electrostatic sensing elements, a plurality of first electrodes, a plurality of second electrostatic sensing elements, and a plurality of third electrodes located on a substrate. Each first electrostatic sensing element and each second electrostatic sensing element include a single walled carbon nanotube or a few-walled carbon nanotube. The resistances of the plurality of first electrostatic sensing elements and the plurality of second electrostatic sensing elements are changed in process of a sensed object with electrostatic near, but does not touch the plurality of first electrostatic sensing elements and the plurality of second electrostatic sensing elements. The hover control unit is electrically connected to the plurality of first electrostatic sensing elements and the plurality of second electrostatic sensing elements.

Abstract: Secrecy scheme systems and associated methods using list source codes for enabling secure communications in communications networks are provided herein. Additionally, improved information-theoretic metrics for characterizing and optimizing said secrecy scheme systems and associated methods are provided herein. One method of secure communication comprises receiving a data file at a first location, encoding the data file using a list source code to generate an encoded file, encrypting a select portion of the data file using a key to generate an encrypted file, and transmitting the encoded file and the encrypted file to an end user at a destination location, wherein the encoded file cannot be decoded at the destination location until the encrypted file has been received and decrypted by the end user, wherein the end user possesses the key.

Abstract: Disclosed herein are glycidol-based polymers, nanoparticles, and methods related thereto useful for a variety of applications, including, but not limited to, drug delivery. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present invention includes compositions and methods of inhibiting or activating TLR7 signaling. In one aspect, a composition includes an inhibitor of TLR7 signaling is described, where the inhibitor of TLR7 signaling is a TLR7 inhibitory oligonucleotide, a TLR7 antibody, or a TLR7 antagonist. In another aspect, a composition and method are described for preventing and treating viral infection of a T cell in a subject. Methods for decreasing T cell proliferation by administering a composition with a TLR7 ligand or agonist or inducing T cell anergy in a subject by stimulating T cells with a TLR7 ligand or agonist are also described.

Abstract: The present invention relates to methods for treating prostate cancer patients. It is based, at least in part, on the discovery that approximately 90% of men carrying at least one of the following fusion genes: TRMT11-GRIK2, SLC45A2-AMACR, MTOR-TP53BP1, LRRC59-FLJ60017, TMEM135-CCDC67 and CCNH-05orf30 experienced prostate cancer recurrence, metastases and/or prostate cancer-specific death after radical prostatectomy (each examples of “progressive prostate cancer”), while these outcomes occurred in only 36% of men not carrying any of these fusion genes. It is also based, at least in part, on the discovery that a genome editing technique that specifically targets a fusion gene can induce cell death in a cancer cell that carries the fusion gene.

Abstract: A system and method for enabling set up of a controlling device capable of controlling a plurality of appliances, via an interactive instruction set and associated programming. The programming is accessible by a STB or other controllable appliance and is configured to appropriately display interactive instructions and prompts to a user during a user initiated set up procedure for configuration of another controllable device (e.g., DVD, VCR, DVR, etc) available to the user. Appropriate set up data, generally in the form of command library codes, is displayed to the user by the interactive instruction set and associated programming for entry and trial by the user in set up of the desired appliance(s).

Abstract: A method of performing one-time password (OTP) authentication using a color code is provided. The method includes generating, by an OTP terminal and an authentication server, an OTP using a reference time, generating, by the OTP terminal, a color code corresponding to a binary code representing the OTP, displaying, by a display device, the color code, obtaining, by a camera, the displayed color code, decoding, by the authentication server, the obtained color code into the color code and generating a password which refers to the decoded binary code, and performing, by the authentication server, authentication by comparing the generated OTP and the password.

Abstract: A negative high-voltage generation device with multi-stage selection includes an input, an output, negative charges pumps, electrical switches, and a control device. The negative charge pumps are electrically cascaded between the input and the output and configured to receive zero voltage through the input. The control device turns off at least one of the electrical switches close to the output and turns on the remains of the plurality of electrical switches, and the negative charge pumps and the electrical switches use zero voltage to generate a negative voltage at the output.

Abstract: An array of optical resonators comprises at least a first type of optical resonators each having a resonant response to an optical field at a first wavelength, and a second type of optical resonators each having a resonant response to an optical field at a second wavelength, being different from the first wavelength. The resonant responses can be selected to reduce chromatic aberrations, or to shape a profile of a light beam, or to selectively switch a near field beam.