Abstract: A method of correcting singletons in a selected AAV sequence in order to increasing the packaging yield, transduction efficiency, and/or gene transfer efficiency of the selected AAV is provided. This method involves altering one or more singletons in the parental AAV capsid to conform the singleton to the amino acid in the corresponding position(s) of the aligned functional AAV capsid sequences.

Abstract: An autophagy-inducing compound comprises an autophagy-inducing peptide comprising Beclin 1 peptides immediately N- and C-terminally flanked by moieties R1 and R2, respectively, wherein up to six of said peptide residues may be substituted, R1 and R2 do not naturally flank the Beclin 1 residues, and F270 and F274 are optionally substituted and optionally linked. The compounds may be used to induce autophagy.

Abstract: An energy exchanger is provided. The exchanger includes a housing having a front and a back. A plurality of panels forming desiccant channels extend from the front to the back of the housing. Air channels are formed between adjacent panels. The air channels are configured to direct an air stream in a direction from the front of the housing to the back of the housing. A desiccant inlet is provided in flow communication with the desiccant channels. A desiccant outlet is provided in flow communication with the desiccant channels. The desiccant channels are configured to channel desiccant from the desiccant inlet to the desiccant outlet in at least one of a counter-flow or cross-flow direction with respect to the direction of the air stream.

Abstract: A method and composition for eliciting an immune response to group A streptococcal bacteria in a mammal is provided, which includes administering to the mammal an M protein fragment, variant or derivative thereof and a SpyCEP protein or peptide fragment, or an antibody to the SpyCEP protein or fragment to facilitate restoring or enhancing neutrophil activity. Also provided is an immunodominant peptide fragment of SpyCEP.

Abstract: A queue management system in accordance with present embodiments may include a data server system including a processor and memory. The queue management system may include an interface system of the data server system configured to receive a reservation request including an indication of a general time period of arrival of a guest to an area. Additionally, the queue management system may include a reservation right allotment system of the data server system configured to correlate a reservation slot for accessing an attraction to identification information for the guest. Further, the queue management system may include a detection system of the data server system configured to determine when a portable identification feature associated with the identification information has arrived to the area, and a reservation assignment system of the data server system configured to establish a reservation to access the attraction at a specific time window.

Abstract: Motion contrast depth scanning is disclosed herein. A disclosed example apparatus includes an illumination source that is to provide at least one of spatial or temporal changes to light emitted from the illumination source to a scene. The example apparatus also includes a motion contrast sensor, where pixels of the motion contrast sensor are to detect changes corresponding to the scene, and where the motion contrast sensor is to report measurements when a pixel change exceeds a threshold. The example apparatus further includes a processor to determine at least one of a reflectance, a depth, or movement of the scene based on the reported measurements by the motion contrast sensor.

Abstract: The present invention relates to a method for imaging a target object within media which bring about simultaneously scattering and aberration capable of imaging of deep depth and high resolution not only by maximizing an accumulation of a single aberration but also by noticeably reducing an distortion of image using simultaneous correction of the scattering and the aberration.

Abstract: The present disclosure relates to a pre-5th-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4th-Generation (4G) communication system such as Long Term Evolution (LTE). A reception method for an electronic device of the present disclosure comprises the steps of: receiving, from a transmission device, first location information including information on the coverage area of the transmission device; generating second location information using the first location information and location information of the electronic device; and determining location information of the transmission device using the second location information and information on the coverage area of the electronic device.

Abstract: A traceable device and procedure suitable for investigating gastrointestinal motility disorders by measuring transit time of the device as it is passed through the gastrointestinal tract of a patient. The device includes a core material configured to be imaged with a gamma imaging process and optionally also an x-ray imaging process, and a sealing material substantially insoluble in gastrointestinal fluids and fully encapsulating the core material.

Abstract: A method of forming a low-dielectric-constant amorphous hydrogenated boron carbide film on a substrate includes positioning the substrate within a plasma enhanced chemical vapor deposition (PECVD) chamber, providing a boron carbide precursor and introducing the boron carbide precursor into a carrier gas to form a carrier gas-precursor mixture. The method also includes introducing the carrier gas-precursor mixture into the PECVD chamber. The method also includes applying radio frequency power within the PECVD chamber to the carrier gas-precursor mixture to form one or more plasmas containing one or more species containing at least one of boron, carbon or hydrogen. The method also includes forming the low-dielectric-constant amorphous hydrogenated boron carbide film on the substrate within the PECVD chamber.

Abstract: A lactic acid bacterium-containing composition including a lactic acid bacterium having a human papillomavirus (HPV) E7 protein-derived polypeptide on a surface thereof, wherein the HPV E7 protein-derived polypeptide is included in an amount of 0.03 ?g to 1.0 ?g per 1×108 lactic acid bacteria; a therapeutic oral pharmaceutical composition for at least one of an HPV infectious disease and an HPV-associated tumor which includes the lactic acid bacterium-containing composition; and a mucosal immunity-inducing agent which includes the lactic acid bacterium-containing composition.

Abstract: A phase change memory apparatus comprises at least one heating layer; and at least one phase change layer comprising a vanadium dioxide layer, wherein each of the at least one phase change layer is set corresponding to each of the at least one heating layer, the at least one heating layer is configured to heat the at least one phase change layer.

Abstract: A pattern matching component is provided. The pattern matching component utilizes a plurality of processors to efficiently identify and retrieve information from a plurality of data sources. In some examples, the pattern matching component concurrently executes multiple portions of a data access plan, such as a query execution plan, using a plurality of processors disposed within a multi-core processor. The pattern matching component may concurrently execute multiple portions of the data access plan using a plurality of processors in a distributed system. Concurrent execution of at least some of the operations required to identify and retrieve the information results in increased efficiency over conventional query execution methods.

Abstract: A system and method for a 3-D motion estimation and online temporal calibration having one or more than one processor, one or more than one camera, one or more than one inertial sensor, a storage for storing data and instructions. The stored instructions comprise a filter estimation module, high-precision navigation instructions and consistent state estimates in scenarios involving features, with both constant and time-varying offsets from the filter estimation module.

Abstract: The method of classifying raw EEG signals uses a classification method based on nuclear features extracted as dominant singular values from an EEG signal segment using singular value decomposition (SVD) and a class means-based minimum distance classifier (CMMDC) to classify a patient's EEG signals. From a mean EEG signal, a set of zero-centered EEG signals are calculated, and from the zero-centered EEG signals and a standard deviation of the EEG signals, a unit variance is calculated for each component. Using the standardized component signals a nuclear matrix is calculated, to which singular value decomposition is applied to generate a set of singular values. The CMMDC is applied to class means associated with first and second classes and a nuclear feature vector to classify the patient's EEG signals as belonging in either the first or second class.

Abstract: In accordance with some embodiments of the present invention, systems and methods that protect an application from attacks are provided. In some embodiments of the present invention, input from an input source, such as traffic from a communication network, can be routed through a filtering proxy that includes one or more filters, classifiers, and/or detectors. In response to the input passing through the filtering proxy to the application, a supervision framework monitors the input for attacks (e.g., code injection attacks). The supervision framework can provide feedback to tune the components of the filtering proxy.

Abstract: A method of preparing a positive electrode active material-solid electrolyte complex for an all-solid-state lithium sulfur battery includes mixing a sulfide based solid electrolyte, which includes Li2S and P2S5, and a positive electrode active material to prepare a mixture; milling the mixture to amorphize the mixture; and heat-treating the amorphized mixture.

Abstract: Provided are methods for the combined use of cyclin-dependent kinase 9 (CDK9) inhibitors and bromodomain containing 4 (BRD4) inhibitors to reduce, inhibit and/or prevent cartilage degradation and systemic traumatic inflammation. A combination of CDK9 inhibitors and BRD4 inhibitors can be used to reduce, inhibit and/or prevent cartilage degradation and loss of cartilage viability during allograft storage. A combination of CDK9 inhibitors and BRD4 inhibitors can be used as a post-injury intervention treatment to reduce, inhibit and/or prevent the acute cellular responses that lead to future cartilage degradation and osteoarthritis.

Abstract: The present disclosure provides a method for generating an affinity reagent library against a target protein which interacts with a ligand, which comprises the following steps; •i) determining one or more structural element(s) of the ligand which are involved in ligand: target protein interaction; •ii) producing a library of peptides which retain these structural element(s); and •iii) grafting each peptide from the library of peptides into a portion of the affinity reagent molecule such that it may interact with the target protein, in order to produce an affinity reagent library.

Abstract: This disclosure provides systems, methods, and apparatus related to solar water splitting. In one aspect, a structure includes a plurality of first nanowires, the plurality of first nanowires comprising an n-type semiconductor or a p-type semiconductor. The structure further includes a second nanowire, the second nanowire comprising the n-type semiconductor or the p-type semiconductor, the second nanowire being a different composition than the plurality of first nanowires. The second nanowire includes a first region and a second region, with the first region having a conductive layer disposed thereon, and each of the plurality of first nanowires being disposed on the conductive layer.