Abstract: Disclosed herein are a method and apparatus for filtering a reference pixel. A method of smoothing a reference pixel may include determining whether or not to perform smoothing on a reference pixel based on the size of a transform block and information about an intra-prediction mode for the transform block and determining a smoothing method by comparing the size of the transform block with the size of a maximum transform block. Accordingly, image coding efficiency can be increased, and picture quality can be improved.
Type:
Grant
Filed:
June 11, 2018
Date of Patent:
August 6, 2019
Assignee:
Research & Business Foundation Sungkyunkwan University
Inventors:
Byeung Woo Jeon, Ho Young Lee, Kwang Hyun Won
Abstract: Provided according to embodiments of the present invention are methods of monitoring individuals that include securing a photoplethysmograph probe to at least one of a pre-auricular region and a post-auricular region of the individual and obtaining photoplethysmography signals from the photoplethysmography probe. Photoplethysmography probes and helmets related to such methods are also described herein.
Type:
Grant
Filed:
July 17, 2017
Date of Patent:
August 6, 2019
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
Richard J. Melker, Neil Euliano, Brian Fuerhlein
Abstract: The present invention relates to a method for preparing a free-standing polymer film with micropores in a simple and economical way, and particularly to a method for preparing a free-standing polymer film with micropores that includes: (a) forming a thin film of a water-soluble polymer on a substrate; (b) forming a thin film of a hydrophobic polymer on the water-soluble polymer thin film; (c) treating the substrate having the polymer thin films formed on with a mixed solution of a solvent and a C1-C3 alcohol and drying the substrate; and (d) immersing the dried substrate in water to dissolve the water-soluble polymer thin film and thereby to peel the hydrophobic polymer thin film from the substrate.
Type:
Grant
Filed:
December 4, 2015
Date of Patent:
August 6, 2019
Assignee:
The Industry & Academic Cooperation in Chungnam National University (IAC)
Abstract: The present invention provides a sun position tracking method based on a black sun effect of an image sensor, a computer program including commands for causing a computer system to perform the method, and a solar sensor using the method. The sun position tracking method includes processing a plurality of images captured using a plurality of image sensors installed to capture a plurality of images of the sun irrespective of the position of the sun to estimate the center point of the black sun and track the position of the sun.
Type:
Grant
Filed:
May 1, 2017
Date of Patent:
August 6, 2019
Assignee:
Research & Business Foundation Sungkyunkwan University
Inventors:
Sukhan Lee, Rashid Saleem, Jaewoong Kim
Abstract: The present invention provides a humanized antibody or antibody fragment comprising (a) a humanized light chain comprising 1) Complementarity Determining Region (CDR)-L1, the sequence of which is identical to the sequence of SEQ ID NO: 3; 2) CDR-L2, the sequence of which is identical to the sequence of SEQ ID NO: 4; and 3) CDR-L3, the sequence of which is identical to the sequence of SEQ ID NO: 5, and (b) a humanized heavy chain comprising 1) CDR-H1, the sequence of which is identical to the sequence of SEQ ID NO: 6; 2) CDR-H2, the sequence of which is identical to the sequence of SEQ ID NO: 7; and 3) CDR-H3, the sequence of which is identical to the sequence of SEQ ID NO: 8, as well as methods for treating, diagnosing, and monitoring the progression of HIT. The present invention also provides methods for assessing the antigenicity and ability to cause HIT of anionic anticoagulants.
Type:
Grant
Filed:
November 5, 2015
Date of Patent:
August 6, 2019
Assignee:
The Trustees of the University of Pennsylvania
Inventors:
Mark I. Greene, Douglas B. Cines, Zheng Cai, Zhiqiang Zhu
Abstract: A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: wherein X is a divalent linking moiety; and R1-R10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R3 or R8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.
Type:
Grant
Filed:
October 10, 2018
Date of Patent:
August 6, 2019
Assignees:
University of Pittsburgh—Of the Commonwealth System of Higher Education, The United States of America as represented by the Department of Veterans Affairs
Abstract: Various systems and methods are implemented for controlling stimulus of a cell. One such method is implemented for optical stimulation of a cell expressing an NpHR ion pump. The method includes the step of providing a sequence of stimuli to the cell. Each stimulus increases the probability of depolarization events occurring in the cell. Light is provided to the cell to activate the expressed NpHR ion pump, thereby decreasing the probability of depolarization events occurring in the cell.
Type:
Grant
Filed:
September 10, 2018
Date of Patent:
August 6, 2019
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Karl Deisseroth, Feng Zhang, Edward Boyden
Abstract: A method for making an organic light emitting diode includes providing a first carbon nanotube composite structure having a first surface and a second surface opposite to the first surface. The first carbon nanotube composite structure includes a polymer and a plurality of first carbon nanotubes dispersed in the polymer. A preform structure includes a support body, an anode electrode, a hole transport layer, and an organic light emitting layer stacked on each other in that order. The preform structure is located on the first surface, wherein the first surface is in direct contact with the organic light emitting layer. A cathode electrode is formed on the second surface.
Type:
Grant
Filed:
December 22, 2017
Date of Patent:
August 6, 2019
Assignees:
Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
Inventors:
Wen Ning, Peng Liu, Kai-Li Jiang, Shou-Shan Fan
Abstract: The problems: It is an object of the present invention to provide an immune regulating agent capable of modulating a receptor function concerning immune regulation of DR6, and a method for screening thereof. The object aims to provide: The present invention relates to an immune regulating agent containing a physiologically active substance having an ability to bind specifically to DR6 and an ability to regulate signal transduction induced by specific binding between DR6 and Sdc1, as an active component. The immune regulating agent of the present invention can be used for treating or preventing diseases caused by excessive or abnormal immune response in mammals or diseases for which enhancement of immune function is desired in mammals, as an immune regulating agent based on a hitherto unknown mechanism, capable of regulating signal transduction induced by specific binding between DR6 and Sdc1.
Type:
Grant
Filed:
November 19, 2014
Date of Patent:
August 6, 2019
Assignee:
National University Corporation Hokkaido University
Abstract: A functionalized magnetic nanoparticle including an organometallic sandwich compound and a magnetic metal oxide. The functionalized magnetic nanoparticle may be reacted with a metal precursor to form a catalyst for various C—C bond forming reactions. The catalyst may be recovered with ease by attracting the catalyst with a magnet.
Type:
Grant
Filed:
October 4, 2018
Date of Patent:
August 6, 2019
Assignee:
Kind Fahd University of Petroleum and Minerals
Inventors:
M. Nasiruzzaman Shaikh, Md. Abdul Aziz, Aasif Helal
Abstract: An image encoding method, decoding method and corresponding device, and intraframe pixel prediction method are disclosed. The image encoding method comprises: pixel segmentation, segmenting pixels in an image frame; pixel value prediction, respectively performing a pixel value prediction process to obtain a first prediction value for each of pixels in a current block to be encoded; a step of residual calculation, calculating a residual for each of the pixels in the current block to be encoded; a step of discrete cosine transform, quantization and entropy encoding, performing discrete cosine transform, quantization and entropy encoding with respect to a residual block corresponding to the current block to be encoded obtained in the residual calculation step, and the entropy encoded residual block is sent to a decoding end; and a pixel value reconstruction step, reconstructing a pixel value of the previously-encoded pixel.
Abstract: A universal base attachment bit and cutting bit assembly includes a base attachment bit and a cutting bit. The base attachment bit includes an outer threaded portion at a first end, a latch at an opposing second end, and at least one multi-sided gripping portion between the latch and the first end. The cutting bit includes a hollow cylindrical outer body and a cylindrical coupling portion within the cylindrical outer body. The cylindrical outer body includes a peripheral wall having opposed first and second open ends and a cutting edge at the first end. The coupling portion is spaced from the peripheral wall of the cylindrical body and includes an inner thread along an inner surface thereof.
Abstract: A reinforced magnesium composite, and a method of producing thereof, wherein the reinforced magnesium composite comprises elemental magnesium particles, elemental nickel particles, and one or more ceramic particles with elemental nickel particles being dispersed within elemental magnesium particles without having intermetallic compounds therebetween. Various embodiments of the method of producing the reinforced magnesium composite are also provided.
Type:
Grant
Filed:
June 14, 2016
Date of Patent:
August 6, 2019
Assignee:
King Fahd University of Petroleum and Minerals
Abstract: A method for determining a location of a disturbance in a power system is provided. The method includes receiving data from a plurality of sensors distributed across the power system; determining, with one or more processors, for each sensor, an extremum of the data corresponding to the sensor; interpolating, with the one or more processors, the extrema; and presenting, on one or more display units, a location corresponding to a global maximum of the interpolated extrema as the location of the disturbance. The method may further include, if a difference between the largest extremum and each of remaining extremum is greater than a predetermined threshold, skipping the interpolating step and the presenting step, and presenting a location of the sensor corresponding to the largest extremum as the location of the disturbance.
Type:
Grant
Filed:
November 16, 2016
Date of Patent:
August 6, 2019
Assignee:
University of Tennessee Research Foundation
Inventors:
Shutang You, Dao Zhou, Ling Wu, Yilu Liu
Abstract: The present invention provides an antibody that specifically binds to human aggrecanase, and inhibits enzymatic activity of the human aggrecanase. In one embodiment, aggrecanase is ADAMTS4. In one embodiment, the antibody recognizes a particular epitope in human ADAMTS4, and inhibits not only aggrecanase activity of human ADAMTS4 but also aggrecanase activity of human ADAMTS5. In addition, the present invention also provides use of said antibody in the prophylaxis or treatment of the progression of arthritis.
Type:
Application
Filed:
October 5, 2018
Publication date:
August 1, 2019
Applicants:
GeneFrontier Corporation, Keio University
Abstract: A water-harvesting system can operate with a material that can take up and release water with minimum energy requirements and powered by low-grade energy sources, such as sunlight, in order to potentially allow its deployment into households, especially those located in sunny regions. A water-harvesting method and system can include vapor adsorption using a porous metal-organic framework. In certain embodiments, the porous metal-organic framework can include metal-organic framework in ambient air with low relative humidity, typical of the levels found in most dry regions of the world.
Type:
Application
Filed:
April 5, 2019
Publication date:
August 1, 2019
Applicants:
The Regents of the University of California, Massachusetts Institute of Technology
Inventors:
Hyunho Kim, Sungwoo Yang, Sameer R. Rao, Shankar Narayanan, Eugene A. Kapustin, Hiroyasu Furukawa, Ari S. Umans, Omar M. Yaghi, Evelyn N. Wang
Abstract: An apparatus for a lead-free piezoelectric ink-jet printhead is disclosed. Piezoelectric printheads, while more expensive are favored because they use a wider variety of inks. The piezoelectric printhead includes a diaphragm, a plurality of piezoelectric actuators comprising a lead-free piezoelectric material, at least one nozzle, at least one ink chamber, a top electrode, and a drive circuit. The deflection of the diaphragm on the body chamber contributes to a pressure pulse that is used to eject a drop of liquid from the nozzle. According to an exemplary embodiment, a lead-free piezoelectric printhead operated at smaller thicknesses and significantly higher electric fields is disclosed, along with methods of making such printheads.
Type:
Application
Filed:
April 5, 2019
Publication date:
August 1, 2019
Applicants:
Xerox Corporation, Brown University
Inventors:
Peter J. Nystrom, Gary D. Redding, Angus Ian Kingon, Seunghyun Kim, Nicholas Mostovych
Abstract: Disclosed are methods and pharmaceutical compositions for treating a cancer in a subject in need thereof, the cancer characterized by proteolytic cleavage by taspase1 of the mixed-lineage leukemia 1 gene product (MLL1), the method comprising administering to the subject a therapeutic agent that inhibits cleavage by taspase1 of MLL1. Suitable therapeutic agents may include agents that inhibit the kinase activity of casein kinase II (CKII). Cancer treated by the disclosed methods and pharmaceutical compositions may include leukemia such as Acute Lymphoblastic Leukemia (ALL) and/or Acute Myeloid Leukemia (AML) and in particular, leukemia characterized by rearrangements in MLL1.