Patents Assigned to University
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Patent number: 10291076Abstract: Wireless power transfer systems including wireless transmitter and receivers, which are insensitive to misalignment, are provided. A wireless power transfer system can include a first conductive loop that has cylindrical, conical, or spherical symmetry. The wireless power transfer system can further include a second conductive loop that is formed around the first conductive loop, and can also share the same type of symmetry as the first conductive loop. The wireless transfer system can be a wearable device or an implantable device.Type: GrantFiled: May 15, 2018Date of Patent: May 14, 2019Assignee: The Florida International University Board of TrusteesInventor: Stavros Georgakopoulos
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Patent number: 10286084Abstract: Provided herein are recombinant constructs, vectors and expression cassettes including a first promoter which is suitably a tRNA promoter operably connected to a first polynucleotide encoding a first single guide RNA and a second promoter operably connected to a second polynucleotide encoding a Cas9 polypeptide. The first single guide RNA includes a first portion complementary to a strand of a target sequence of a DNA virus and a second portion capable of interacting with the Cas9 polypeptide. Also provided are codon optimized Staphylococcus aureus derived Cas9 polynucleotides and polypeptides with nuclear localization signals and optionally an epitope tag. Also provided are constructs for production of sgRNAs including a tRNA. Methods of inhibiting viral replication, inhibiting expression of a target sequence from a virus or treating a viral infection or viral induced cancer using the compositions are also provided.Type: GrantFiled: February 18, 2015Date of Patent: May 14, 2019Assignees: Duke University, Emory University, The United States of America as Represented by the Department of Veterans AffairsInventors: Bryan R. Cullen, E. Matthew Kennedy, Hal P. Bogerd, Anand Kornepati, Adam Mefferd, Raymond F. Schinazi
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Patent number: 10287173Abstract: An ammonia-producing system comprises a reactor that catalytically converts nitrogen and hydrogen feed gases to ammonia to form a reaction mixture of the ammonia, unreacted nitrogen gas, and unreacted hydrogen gas. A feed system feeds the nitrogen and hydrogen gases to the reactor at a reaction pressure of from about 9 to about 100 atmospheres. A reactor control system controls the temperature during conversion of the nitrogen and hydrogen to ammonia by maintaining a reaction temperature of from about 330° C. to about 550° C. An absorbent selectively absorbs at least a portion of the ammonia from the reaction mixture, and an absorbent control system controls one or both of a temperature and pressure at the absorbent during selective absorption of the ammonia from the reaction mixture. A recycle line downstream of the absorbent recycles the unreacted nitrogen and unreacted hydrogen to the reactor.Type: GrantFiled: February 14, 2017Date of Patent: May 14, 2019Assignee: Regents of the University of MinnesotaInventors: Mohammadmahdi Malmali, Alon V. McCormick, Edward L. Cussler
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Patent number: 10285641Abstract: A vital signal measuring watch is provided, the vital signal measuring watch including a watch module having a shape of a wrist watch, wherein the watch module includes a device receiving portion at one side of the watch module and a communication port in the device receiving portion; and a vital signal sensor connected to or disconnected from the device receiving portion, connected to the communication port when being connected to the device receiving portion, and configured to transmit biometric data obtained by measuring vital signals to the communication port, wherein the vital signal sensor is configured to generate an interrupt plug-in event to transmit the event to the watch module when being connected to the communication port, and the watch module is configured to count a number of interrupts of the transmitted interrupt plug-in event, automatically recognize a communication protocol supported by the vital signal sensor according to the number of interrupts, and dynamically activate a communication iType: GrantFiled: March 26, 2014Date of Patent: May 14, 2019Assignee: Kyungpook National University Industry-Academic Cooperation FoundationInventors: Soon Ju Kang, Cheol Soo Ahn, Kyung Chun Lee, Yu Jin Park
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Patent number: 10285940Abstract: The present invention is directed to emulsions with a plurality of droplets dispersed in a continuous liquid medium. These droplets can contain at least a first droplet liquid and a second droplet liquid and can have an ensemble-average maximal spatial dimension that is less than 1 micrometer. The invention includes preparation, uses and compositions containing emulsions. Solute materials can also be dissolved in the droplet liquids.Type: GrantFiled: October 2, 2014Date of Patent: May 14, 2019Assignee: The Regents of the University of CaliforniaInventors: Thomas G. Mason, Michael M. Fryd
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Patent number: 10285984Abstract: A method and a composition for improving gut micro biota structure, selectively increase a first gut microbiota population while simultaneously decrease a second gut micro biota population in a subject. The first gut micro biota population includes a short-chain fatty acid (SCFA)-producing bacterium and the second gut microbiota population includes an endotoxin-producing bacterium.Type: GrantFiled: June 4, 2013Date of Patent: May 14, 2019Assignee: Shanghai Jiao Tong UniversityInventors: Liping Zhao, Xu Zhang, Menghui Zhang, Yufeng Zhao, Xiaoyan Pang, Xiaojun Zhang, Linghua Wang, Guang Ning, Xiaoying Li, Yifei Zhang
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Patent number: 10290767Abstract: GaN-based nanowire heterostructures have been intensively studied for applications in light emitting diodes (LEDs), lasers, solar cells and solar fuel devices. Surface charge properties play a dominant role on the device performance and have been addressed within the prior art by use of a relatively thick large bandgap AlGaN shell covering the surfaces of axial InGaN nanowire LED heterostructures has been explored and shown substantial promise in reducing surface recombination leading to improved carrier injection efficiency and output power. However, these lead to increased complexity in device design, growth and fabrication processes thereby reducing yield/performance and increasing costs for devices. Accordingly, there are taught self-organizing InGaN/AlGaN core-shell quaternary nanowire heterostructures wherein the In-rich core and Al-rich shell spontaneously form during the growth process.Type: GrantFiled: June 9, 2016Date of Patent: May 14, 2019Assignee: The Royal Institution for the Advancement of Learning/McGill UniversityInventors: Zetian Mi, Songrui Zhao, Renjie Wang
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Patent number: 10287376Abstract: A method for producing an amphiphilic particle or an anisotropic particle includes combining seed particles with a monomer emulsion to obtain monomer-swollen seed particles, polymerizing the monomer-swollen seed particles to obtain polymerized monomer-swollen particles, and hydrolyzing the polymerized monomer-swollen particles. An amphiphilic particle is adapted to stabilize a first type of multiphasic mixture comprising a first aqueous phase having a first pH and a second type of multiphasic mixture comprising a second aqueous phase having a second pH.Type: GrantFiled: January 12, 2017Date of Patent: May 14, 2019Assignee: The Trustee of the University of PennsylvaniaInventors: Daeyeon Lee, Fuquan Tu
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Patent number: 10287657Abstract: There is provided a Mg—N-A based magnesium material (A is a metal or non-metal element configuring a nitride, N: nitrogen originating from the nitride). The magnesium material includes a spherical Mg—N-A eutectic phase and nitrogen atoms are dispersed in a magnesium matrix, whereby mechanical and ignition properties of the magnesium material are improved, as compared to a magnesium material or pure magnesium material in which the nitrogen atoms are not included and only the metal or non-metal element is included.Type: GrantFiled: April 13, 2015Date of Patent: May 14, 2019Assignee: Industry-Academic Cooperation Foundation, Yonsei UniversityInventors: DongHyun Bae, Hun Kang, SeungWon Kang
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Patent number: 10288599Abstract: Embodiments of the disclosure are directed to a device for molecule sensing. In some embodiments, the device includes a first electrode separated from a second electrode by a dielectric layer. The first electrode comprises a large area electrode and the second electrode comprises a small area electrode. At least one opening (e.g., trench) cut or otherwise created into the dielectric layer exposes a tunnel junction therebetween whereby target molecules in solution can bind across the tunnel junction.Type: GrantFiled: January 21, 2016Date of Patent: May 14, 2019Assignee: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Brett Gyarfas, Stuart Lindsay, Pei Pang
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Patent number: 10286119Abstract: Provided are surgical meshes embedded in a gelled, solubilized extracellular matrix (ECM) composition, methods of making the same, and methods of using the same to repair defects in a body. The surgical mesh may be a synthetic polymer such as polypropylene, and the ECM coating reduces the foreign body response and scarring at the site of implantation. The device is useful for repairing hernias, pelvic floor disorders, and in breast reconstructions.Type: GrantFiled: January 23, 2015Date of Patent: May 14, 2019Assignee: University of Pittsburgh—of the Commonwealth System of Higher EducationInventors: Stephen F. Badylak, Matthew T. Wolf
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Patent number: 10289194Abstract: A ride system for an amusement park includes a ride vehicle configured to accommodate a rider and configured to travel along a ride path, a head mounted display configured to be worn by the rider, and a control system. The control system is configured to display a virtual instruction to the rider via the head mounted display, receive a signal from a user input device associated with the rider, determine that the signal received from the user input device corresponds to the virtual instruction, and trigger a movement of the ride vehicle in response to determining that the signal corresponds to the virtual instruction.Type: GrantFiled: March 5, 2018Date of Patent: May 14, 2019Assignee: Universal City Studios LLCInventors: Sean David McCracken, Eric Lawrence Merz, Patrick Devin Boyle, Justin Michael Schwartz, Thomas Martin Geraghty
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Patent number: 10287578Abstract: The present invention relates to DNAzymes (also known as deoxyribozymes, DNA enzymes, catalytic DNA, or DZ), which are conjugated to nanoparticles (NP) to facilitate the detection of nucleic acids. One aspect of the invention relates to compounds comprising DNAzymes conjugated to nanoparticles (DZ-NP), such as metallic or gold nanoparticles, and methods for their synthesis. Another aspect of the invention relates to methods of using the conjugated compounds to detect nucleic acids, such as genomic material or transcripts of infectious agents, such as viruses, exemplified by applications demonstrating visual detection of Flavivirus RNA molecules, such as dengue virus, or Alphavirus RNA molecules, such as chikungunya virus, in short time periods, using compositions comprising stable components.Type: GrantFiled: June 16, 2014Date of Patent: May 14, 2019Assignee: The University of Notre DameInventors: James Carter, Malcolm J. Fraser, Jr.
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Patent number: 10287640Abstract: Provided is an isolated mammalian negative strand RNA virus, metapneumovirus (MPV), within the sub-family Pneumoviridae, of the family Paramyxoviridae. Also provided are isolated mammalian negative strand RNA viruses identifiable as phylogenetically corresponding or relating to the genus Metapneumovirus and components thereof. In particular, provided is a mammalian MPV, subgroups and variants thereof. Also provided are genomic nucleotide sequences of different isolates of mammalian MPV, in particular, human MPV. Disclosed is the use of the sequence information of different isolates of mammalian MPV for diagnostic and therapeutic methods. Provided are nucleotide sequences encoding the genome of an MPV or a portion thereof, including both mammalian and avian MPV. Further described are chimeric or recombinant viruses encoded by the nucleotide sequences and chimeric and recombinant mammalian MPV that comprise one or more non-native or heterologous sequences.Type: GrantFiled: March 29, 2018Date of Patent: May 14, 2019Assignee: Erasmus University Medical Center RotterdamInventors: Ronaldus Adrianus Maria Fouchier, Bernadetta Gerarda Van Den Hoogen, Albertus Dominicus Marcellinus Erasmus Osterhaus, Jan Cornelius De Jong, Jan Groen
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Patent number: 10286713Abstract: Methods and chemistries are described to form electrically conductive adhesion promoters for use with reactive inks. In some implementations, a metal ink is printed on a substrate. An adhesion promoter is deposited on the surface of the substrate. The adhesion promoter reacts to form a covalent bond with the substrate. Subsequently, a reactive metal ink is used to print on a substrate using a drop-on-demand printing process. The reactive metal ink includes metal cations that react with the adhesion promoter-treated substrate surface to form a conductive bond between the adhesion promoter-treated substrate surface and a metal of the reactive metal ink.Type: GrantFiled: October 11, 2017Date of Patent: May 14, 2019Assignee: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Owen Hildreth, April Jeffries, Avinash Mamidanna, Mariana Bertoni
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Patent number: 10287586Abstract: An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 59.Type: GrantFiled: July 27, 2017Date of Patent: May 14, 2019Assignee: The University of Western AustraliaInventors: Stephen Donald Wilson, Sue Fletcher, Abbie Adams, Penny Meloni
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Patent number: 10290808Abstract: A method and structure for providing uniform, large-area graphene by way of a transfer-free, direct-growth process. In some embodiments, a SAM is used as a carbon source for direct graphene synthesis on a substrate. For example, a SAM is formed on an insulating surface, and a metal layer is formed over the SAM. The metal layer may serve as a catalytic metal, whereby the SAM is converted to graphene following an annealing process. The SAM is deposited using a VPD process (e.g., an ALD process and/or an MLD process). In some embodiments, a CNT having a controlled diameter may be formed on the surface of a nanorod by appropriately tuning the geometry of the nanorod. Additionally, in some embodiments, a curved graphene transistor may be formed over a curved oxide surface, thereby providing a band gap in a channel region of the graphene transistor.Type: GrantFiled: March 19, 2018Date of Patent: May 14, 2019Assignees: Taiwan Semiconductor Manufacturing Co., Ltd., National Taiwan UniversityInventors: Miin-Jang Chen, Samuel C. Pan, Chung-Yen Hsieh
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Patent number: 10285604Abstract: According to one embodiment, a medical image diagnostic apparatus includes a storage unit, a blood flow information generation unit and a blood flow inhibition index generation unit. The storage unit stores volume data or data of a series of images regarding an organ of an object. The blood flow information generation unit generates, based on the volume data or the data of the series of images, first blood flow information of a first region and second blood flow information of a second region different from the first region. The blood flow inhibition index generation unit generates, based on the first blood flow information and the second blood flow information, a blood flow inhibition index representing a degree of inhibition of a blood flow in a blood vessel regarding the first region or the second region.Type: GrantFiled: August 7, 2014Date of Patent: May 14, 2019Assignees: Fujita Health University, Toshiba Medical Systems CorporationInventors: Takashi Ichihara, Takuya Sakaguchi
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Patent number: 10289955Abstract: Systems and methods for predicting virality of a content item are disclosed. A method includes: receiving a social network structure; identifying communities within the social network structure, where communities are identified as dense subnetworks in the social network structure; receiving social network content that includes one or more content items; and identifying one or more content items that are predicted to become viral based on utilization of the content items between different communities in the social network structure.Type: GrantFiled: March 12, 2014Date of Patent: May 14, 2019Assignee: Indiana University Research and Technology CorporationInventors: Filippo Menczer, Lilian Weng, Yong Yeol Ahn, Jr.
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Patent number: 10286106Abstract: A shape memory polymer (SMP) intraocular lens may have a refractive index above 1.45, a Tg between 10° C. and 60° C., inclusive, de minimis or an absence of glistening, and substantially 100% transmissivity of light in the visible spectrum. The intraocular lens is then rolled at a temperature above Tg of the SMP material. The intraocular device is radially compressed within a die to a diameter of less than or equal to 1.8 mm while maintaining the temperature above Tg. The compressed intraocular lens device may be inserted through an incision less than 2 mm wide in a cornea or sclera or other anatomical structure. The lens can be inserted into the capsular bag, the ciliary sulcus, or other cavity through the incision. The SMP can substantially achieve refractive index values of greater than or equal to 1.45.Type: GrantFiled: May 17, 2016Date of Patent: May 14, 2019Assignee: The Regents of the University of ColoradoInventors: Malik Y. Kahook, Naresh Mandava, Robin Shandas, Bryan Rech