Abstract: The objective of the present invention is to provide a carbon-based hydrogen storage material having an autocatalytic capability, and a production method therefor. The present invention provides a carbon-based hydrogen storage material having an atomic defect, which is a hydrogen adsorbing-storing hydrocarbon compound having an autocatalysis reaction, wherefrom hydrogen that has been adsorbed and stored within the compound is either released while no heat is absorbed, or released while heat is generated.

Abstract: A method for characterizing disease-associated microbial marker genes comprising: counting k-mers of at least two samples; loading k-mers into an array; extracting reads based on differential sequence signatures; and assembling contigs and phylogenetically annotating the contigs.

Abstract: This disclosure provides systems, methods, and apparatus related to light detection and ranging. In one aspect, a method comprises providing an apparatus. The apparatus comprises a LiDAR unit and a LiDAR enclosure. The LiDAR enclosure comprises a four-sided container having a square or rectangular cross-section with a first open end and a second open end comprising two opposite ends of the four-sided container. The LiDAR unit is attached to a mounting area inside the four-sided container. A reflective material is disposed on an interior of a second side and a third side of the four-sided container. Laser light is generated with the LiDAR unit. The laser light that has interacted with environment surrounding the LiDAR enclosure and that has been reflected back to the LiDAR unit is detected. The detected laser light is processed to construct an image of the environment surrounding the LiDAR enclosure.

Abstract: Provided are novel human tau-specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for tau are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for tau targeted immunotherapy and diagnosis, respectively.

Abstract: Functionally graded graphene materials, methods of making and uses thereof are described.

Abstract: Reflectionless low-pass, high-pass, band-pass, band-stop, all-pass, all-stop, and multi-band filters, as well as a method for designing such filters is disclosed, along with a method of enhancing the performance of such filters through the use of unmatched sub-networks to realize an optimal frequency response, such as the Chebyshev equal-ripple response. These filters preferably function by absorbing the stop-band portion of the spectrum rather than reflecting it back to the source, which has significant advantages in many different applications. The unmatched sub-networks preferably offer additional degrees of freedom by which element values can be assigned to realize improved cutoff sharpness, stop-band rejection, or other measures of performance.

Abstract: A sensor device for detecting a target microorganism in tap water in real time, the sensor device includes: a substrate; and a microorganism detection unit configured to detect the target microorganism. A microorganism mounting unit and a signal recognition unit are provided on the microorganism detection unit, and a hydrothermal synthesis unit and a signal disturbance blocking unit are provided on the signal recognition unit to detect an electrochemical reaction occurring in the microorganism mounting unit as an impedance signal value and to measure or detect the target microorganism.

Abstract: Systems and methods provide a nonreciprocal nanophotonic modulator. In some examples, the modulator utilizes acoustic pumping, instead of optical pumping with lasers, and is capable of achieving GHz bandwidth.

Abstract: Methods for combinatorial choice in topology optimization are disclosed. In one embodiment, a method of performing combinatorial choice in a non-linear programming problem for designing a structure includes establishing, by one or more processors, a set of K variables, wherein the set of K variables defines an K-dimensional unit cube in a normal coordinate system. The K-dimensional unit cube includes a plurality of desired vertices representing a plurality of desired combinations that satisfy a constraint and a plurality of undesired vertices representing a plurality of undesired combinations that do not satisfy the constraint. The method further includes transforming the K-dimensional unit cube into a transformed shape in a transformed coordinate system using a shape function. Values of the set of K variables cannot have a combination represented by the plurality of undesired combinations.

Abstract: Methods and reactors for electrochemically expanding a parent material and expanded parent materials are described. Current methods of expanding parent materials incompletely-expand parent material, requiring expensive and time-consuming separation of expanded parent material from unexpanded parent materials. This problem is addressed by the methods and reactor for electrochemically expanding a parent material described herein, which during operation maintain electrical connectivity between the parent material and an electrical power source. The resulting materials described herein have a greater proportion of expanded parent material relative to unexpanded parent material compared to those made according to others methods.

Abstract: A power semiconductor device including a first conductivity type semiconductor substrate, a drain metal electrode, a first conductivity type semiconductor drift region, and a second conductivity type semiconductor body region. The second conductivity type semiconductor body region includes a first conductivity type semiconductor source region and anti-punch-through structure; the anti-punch-through structure is a second conductivity type semiconductor body contact region or metal structure; the lower surface of the anti-punch-through structure coincides with the upper surface of the first conductivity type semiconductor drift region or the distance between the two is less than 0.5 ?m, so that make the device avoid from punch-through. An anti-punch-through structure is introduced at the source end of the device to avoid punch-through breakdown caused by short channel and light-doped body region.

Abstract: An electrochemical reactor for use with a liquid electrolyte is capable of generating gaseous products. An electrically conducting porous layer that is hydrophilic on the catalyst side and hydrophobic on the gas side are utilized. These different surface properties promote the transport of product gases formed at the catalyst through the porous layer to the gas side. The catalyst is formed from a hybrid Cu2O—CuBr film that has a high selectivity for ethylene gas from reacting CO2 and water in an electrochemical cell.

Abstract: The present invention relates to a vaccine composition comprising cyclic peptides of the present invention, antibodies to cyclic peptides, or an anticancer composition comprising them, and the vaccine composition of the present invention exhibit an inhibitory activity for metastasis of cancer. In addition, the antibodies of the present invention bind to the tumor-specific antigen TM4SF5 with high affinity, and significantly inhibit the growth, metastasis and invasion of cancer cells expressing the tumor-specific antigen TM4SF5, and thus can be used for diagnosis, prevention or treatment of various cancers expressing TM4SF5.

Abstract: A method of treating a disease condition in a mammal comprising administering a pharmacologically effective amount of a therapeutic, wherein the therapeutic includes a bioisosteres of caffeic acid. A pharmaceutical composition for treating a disease condition in a mammal comprising a first therapeutic that includes a bioisosteres of caffeic acid, wherein the condition may be breast cancer, and the pharmaceutical composition may include a second therapeutic for the disease condition that is not a bioisosteres of caffeic acid.

Abstract: The present disclosure is a heat radiator for an aircraft which cools a heat source installed in the aircraft, which includes a heat radiating part in which a contact surface comes into contact with a main flow, the contact surface being formed with a concave portion or a convex portion in which a surface thereof directed upstream in a flow direction of the main flow is curved in a plan view.

Abstract: The present invention provides a mucosal immunomodulator comprising, as an active ingredient, at least one selected from the group consisting of compounds represented by the following formula (1), compounds represented by the following formula (2) and compounds represented by the following formula (3), and salts thereof.

Abstract: The present invention includes a method for excluding patients from the need for further analysis of Alzheimer's Disease comprising: obtaining a blood or serum sample from a patient in a primary care setting; determining the expression levels of at least 4 of the following proteins: FABP, beta 2 microglobulin, PPY, soluble tumor necrosis factor receptor 1 (sTNFR1), CRP, VCAM-1, thrombopoietin, ?2 macroglobulin, eotaxin 3, tumor necrosis factor-alpha (TNF-?), tenascin C (TNC), IL-5, IL-6, IL-7, IL-10, IL-18, 1309, Factor VII, thymus and activation-regulated chemokine (TARC), serum amyloid A (SAA), and intercellular cell-adhesion molecule-1 (ICAM-1); comparing the level of expression from the sample with a statistically locked-down, multi-ethnic, broad age spectrum statistical sample; and determining if the patient is excluded from further testing for Alzheimer's Disease, thereby eliminating the need for further testing of the patient.

Abstract: Enabling quick feature delivery is essential for product success and is therefore a goal of software architecture design. But how may we determine if and to what extent an architecture is “good enough” to support feature addition and modification, or determine if a refactoring effort is successful in that features may be added more easily? The applications may use Feature Space and Feature Dependency, derived from a software project's revision history that capture the dependency relations among the features of a system in a feature dependency structure matrix (FDSM), using features as first-class design elements. The applications may also use a Feature Decoupling Level (FDL) metric that may be used to measure the level of independence among features.

Abstract: An exoskeleton includes two torque generators, thigh links, and a supporting trunk rotatably coupled to the thigh links. When a wearer bends forward in the sagittal plane such that the supporting trunk extends beyond a predetermined angle A with respect to vertical, at least one of the torque generators imposes a resisting torque between the supporting trunk and a corresponding thigh link, thus imposing a force onto a wearer's trunk and thighs to aid in supporting the wearer in a bent position. The exoskeleton may include an active or passive means for actuating the torque generators. When the supporting trunk does not extend beyond the predetermined angle A, the torque generators do not impose resisting torques between the supporting trunk and thigh links during the entire range of motion of the thigh links, thus enabling a wearer to walk, run, and sit without constraint while in a substantially upright position.

Abstract: The present invention relates to a transmission electron microscope (TEM) micro-grid and a method for preparing the TEM micro-grid. The TEM micro-grid comprises a porous silicon nitride substrate and a graphene layer located on a surface of the porous silicon nitride substrate. The porous silicon nitride substrate comprises a plurality of through holes. The graphene layer covers the plurality of through holes. The method for preparing the TEM micro-grid provided in the present disclosure uses a carbon nanotube film structure to transfer a graphene layer to a surface of a porous silicon nitride substrate.