Patents Assigned to University
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Publication number: 20190135851Abstract: This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3?-position of the deoxyribose.Type: ApplicationFiled: November 26, 2018Publication date: May 9, 2019Applicant: The Trustees of Columbia University in the City of New YorkInventors: Jingyue Ju, Zengmin Li, John Robert Edwards, Yasuhiro Itagaki
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Publication number: 20190135628Abstract: A power generation system that includes a membrane reformer assembly, wherein syngas is formed from a steam reforming reaction of natural gas and steam, and wherein hydrogen is separated from the syngas via a hydrogen-permeable membrane, a combustor for an oxy-combustion of a fuel, an expander to generate power, and an ion transport membrane assembly, wherein oxygen is separated from an oxygen-containing stream to be combusted in the combustor. Various embodiments of the power generation system and a process for generating power using the same are provided.Type: ApplicationFiled: January 8, 2019Publication date: May 9, 2019Applicant: King Fahd University of Petroleum and MineralsInventors: Esmail Mohamed Ali Mokheimer, Yinka Sofihullahi Sanusi, Mohamed A. Habib
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Publication number: 20190134285Abstract: An implantable anastomotic assembly, which is configured to be attached to cardiovascular tissue, includes a connection interface, a plurality of outer plates, and a plurality of connectors configured to extend between and interconnect the connection interface and the plurality of outer plates, respectively, according to various embodiments. An outer plate of the plurality of outer plates is configured to be engaged against the cardiovascular tissue before a respective connector of the plurality of connectors is interconnected between the connection interface and the outer plate of the plurality of outer plates, according to various embodiments.Type: ApplicationFiled: November 8, 2018Publication date: May 9, 2019Applicant: The Regents of the University of Colorado, a body corporateInventors: Max Bannister Mitchell, Alexander Travis Brown
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Publication number: 20190137635Abstract: Some embodiments include an electronic device. The electronic device includes a first scintillator layer, a transistor, and one or more device elements over the transistor, and the one or more device elements include a photodetector. Meanwhile, the first scintillator layer is monolithically integrated with at least one of the transistor or the one or more device elements. Other embodiments of related systems, devices, and methods are also disclosed.Type: ApplicationFiled: December 14, 2018Publication date: May 9, 2019Applicant: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Xan Henderson, Michael Marrs
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Patent number: 10281889Abstract: A control system to guide a crowd, including a detection module to provide stepping signals from the crowd via a plurality of detectors placed on a walking surface of the control system, a sorting module to provide a favorable path for the crowd, the sorting module including a plurality of movable walls, each movable wall of the plurality of movable walls being independently articulated from an open position to a closed position to provide the favorable path, and an electrical control module configured to convert the stepping signals into statistics, determine the favorable path based on the statistics, and articulate the plurality of movable walls to force the crowd through the favorable path.Type: GrantFiled: December 4, 2017Date of Patent: May 7, 2019Assignee: Imam Abdulrahman Bin Faisal UniversityInventors: Alanoud Mohammed Alqarni, Bayan Saad Alharthi, Hanan Saad Alharthi, Alya Mushaykhis Algarni, Shatha Dhafer Algarni
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Patent number: 10281262Abstract: An imaging laser range finder including an objective lens having an optical axis, an object side, and an image side, a controllable pixelated light modulator disposed along the optical axis on the image side of the lens, and a detector disposed optically downstream from the pixelated light modulator on the image side of the lens. The controllable pixelated light modulator is advantageously a MEMS-based system such as a digital mirror device (DMD). An increased field of view may be obtained by incorporating a pair of opposing surface reflectors between an imaging lens and the controllable pixelated light modulator. Associated methods are disclosed.Type: GrantFiled: August 19, 2016Date of Patent: May 7, 2019Assignee: Arizona Board of Regents on Behalf of the University of ArizonaInventor: Yuzuru Takashima
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Patent number: 10279020Abstract: The invention relates to the fields of medicine, immunology, and oncology. More specifically, the invention relates to methods and compositions for inducing an immune response against a tumor in an animal subject. The invention provides that a lung cancer cell or other tumor cells, genetically modified to express a nucleic acid encoding CD80 (B7.1) and a nucleic acid encoding an HLA antigen, and method for stimulating an immune response to a tumor with the tumor cell so genetically modified. The invention additionally provides a method of inhibiting a tumor, including a cancer such as lung cancer, by administering an allogeneic tumor cell, for example a cancer tumor cell such as a lung cancer tumor cell, genetically modified to express a nucleic acid encoding CD80 (B7.1) and a nucleic acid encoding an HLA antigen.Type: GrantFiled: July 29, 2015Date of Patent: May 7, 2019Assignee: University of MiamiInventor: Eckhard R. Podack
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Patent number: 10281377Abstract: The present invention discloses a sample loading apparatus for laser ablation, including a target seat, a base, an air channel, an aerosol channel and a sample chamber, wherein a shrinking mouth is formed in the top of the sample chamber and positioned on a lower surface of the aerosol channel; a spring is arranged in the sample chamber; an opening is formed in a lower surface of the sample chamber and communicated with an air outlet; a stop valve is arranged at the air outlet; one end of the aerosol channel is communicated with a carrier gas inlet, and the other end is communicated with an aerosol outlet; and a top of the aerosol channel includes a first transparent material. The present invention increases stable reliability in a continuous use process, and improves consistency of aerosol transmission efficiency, so that different samples are analyzed.Type: GrantFiled: March 31, 2018Date of Patent: May 7, 2019Assignee: Northwest UniversityInventors: Honglin Yuan, Kaiyun Chen, Zhian Bao
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Patent number: 10283354Abstract: The invention includes a method of promoting thin film growth on a solid substrate, wherein derivatization of the substrate comprises formation of at least one surface species. In certain embodiments, the method comprises desorbing the surface species from the substrate using electron stimulated desorption (ESD).Type: GrantFiled: September 22, 2014Date of Patent: May 7, 2019Assignee: The Regents of the University of Colorado, a body corporateInventors: Steven M. George, Andrew S. Cavanagh
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Patent number: 10283561Abstract: This disclosure describes an example device that includes a first contact line, a second contact line, a spin-orbital coupling channel, and a magnet. The spin-orbital coupling channel is coupled to, and is positioned between, the first contact line and second contact line. The magnet is coupled to the spin-orbital coupling channel and positioned between the first contact line and the second contact line. A resistance of the magnet and spin-orbital coupling channel is a unidirectional magnetoresistance.Type: GrantFiled: December 12, 2017Date of Patent: May 7, 2019Assignee: Regents of the University of MinnesotaInventors: Jian-Ping Wang, Yang Lv, Mahdi Jamali
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Patent number: 10278405Abstract: The present invention concerns compositions and methods relating to the addition and use of par-baked and milled coffee beans in food products, beverages, and dietary supplements. Par-baked and milled coffee beans are a novel alternative to more costly chlorogenic acid extracts, and are edible and palatable as a food ingredient. The ingredient is prepared from the entire Coffea robusta or arabica green coffee bean and provides substantially increased amounts of dietary chlorogenic acid antioxidants compared to roasted beans. When the green coffee bean is appropriately par-baked at a temperature significantly lower than coffee roasting temperatures, the bean retains significant moisture, yet becomes embrittled, enabling milling to produce fine and beneficially hydrophilic particles, without any significant loss of bioactive chlorogenic acid and without significant pyrolysis occurring.Type: GrantFiled: March 8, 2018Date of Patent: May 7, 2019Assignee: Brandeis UniversityInventor: Daniel Perlman
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Patent number: 10284356Abstract: A wireless communication device includes, in part, an analog interference cancellation circuit and a controller. The analog cancellation circuit includes a multitude of delay paths each including a delay element and a variable attenuator. The controller dynamically varies the attenuation level of each of the variable attenuators in accordance with the frequency response characteristic of that attenuator to remove a portion of a self-interference signal present in a signal received by the device. The device measures the frequency response characteristic of the communication channel, used in determining the attenuation levels, via one or more preamble symbols. A second portion of the self-interference signal is removed by the device using a multitude of samples of a transmitted signal and a multitude of samples of a signal to be transmitted.Type: GrantFiled: August 11, 2014Date of Patent: May 7, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Dinesh Bharadia, Sachin Katti, Emily McMilin, Mayank Jain, Jung Il Choi, Kannan Srinivasan
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Patent number: 10283794Abstract: A porous solid oxide fuel cell (PSOFC) system for electricity and syngas co-generation. The system has a porous layer, a porous electrolyte layer with catalyst, a porous anode layer, and a porous catalyst layer. A fuel air/O2 mixture is introduced from through the porous cathode layer so that it next passes through the porous electrolyte layer with catalyst, then the porous anode layer, and finally the porous catalyst layer. Syngas exits the porous catalyst layer with electricity being produced across the anode and cathode layers.Type: GrantFiled: December 8, 2016Date of Patent: May 7, 2019Assignee: Syracuse UniversityInventors: Jeongmin Ahn, Ryan Milcarek, Kang Wang, Pingying Zeng
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Patent number: 10283658Abstract: Photovoltaic (PV) and photodetector (PD) devices, comprising a plurality of interband cascade (IC) stages, wherein the IC stages comprise an absorption region with a type-I superlattice and/or a bulk semiconductor material having a band gap, the absorption region configured to absorb photons, an intraband transport region configured to act as a hole barrier, and an interband tunneling region configured to act as an electron barrier, wherein the absorption region, the intraband transport region, and the interband tunneling region are positioned such that electrons will flow from the absorption region to the intraband transport region to the interband tunneling region.Type: GrantFiled: September 14, 2015Date of Patent: May 7, 2019Assignee: The Board of Regents of the University of OklahomaInventor: Rui Q. Yang
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Patent number: 10280369Abstract: Thermal barrier mixtures and method of making the thermal barrier mixtures are described herein. The thermal barrier mixtures may be used to make thermal barrier coatings. Thermal barrier mixture may include halloysite and one or more silicon compounds.Type: GrantFiled: April 22, 2013Date of Patent: May 7, 2019Assignee: Board of Regents of the University of Texas SystemInventors: Charles J. Neef, John Lee Massingill, Jr., Clois E. Powell
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Patent number: 10281547Abstract: Apparatus, methods, and other embodiments associated with NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. Sampling is performed in response to a diffusion-weighted double-echo pulse sequence. Sampling acquires transient-state signals of the double-echo sequence. The NMR apparatus may also include a signal logic that produces an NMR signal evolution from the NMR signals, and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals.Type: GrantFiled: April 21, 2014Date of Patent: May 7, 2019Assignee: Case Western Reserve UniversityInventors: Mark Griswold, Vikas Gulani, Dan Ma, Yun Jiang, Katherine Wright
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Patent number: 10280432Abstract: The invention relates to genetically modified agricultural plants with increased oil content in vegetative tissues, as well as to expression systems, plant cells, seeds and vegetative tissues related thereto.Type: GrantFiled: April 13, 2017Date of Patent: May 7, 2019Assignee: Board of Trustees of Michigan State UniversityInventors: Christoph Benning, Sanjaya
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Patent number: 10278384Abstract: In one representative embodiment, a method of perfusing organs in a patient's body is provided. The method comprises isolating the visceral arteries and the visceral veins from blood circulating through the patient's heart and perfusing the visceral arteries, the visceral veins, and the abdominal organs with a perfusion fluid that is fluidly separated from the blood circulating through the patient's heart. While the visceral arteries and the visceral veins are isolated, and the visceral arteries, the visceral veins, and the abdominal organs are being perfused, the patient's blood is allowed to continue to circulate through the heart.Type: GrantFiled: December 2, 2014Date of Patent: May 7, 2019Assignee: University of Pittsburgh—Of the Commonwealth System of Higher EducationInventors: Bryan W. Tillman, Amit D. Tevar, Youngjae Chun
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Patent number: 10280294Abstract: The present invention provides, among other things, compositions comprising nanofibrils, at least one maleic-anhydride (MA) copolymer and at least one matrix polymer, and methods of making such compositions. The provided methods and compositions allow for the production of composites with unexpectedly superior properties including improved impact resistance, tensile modulus of elasticity, tensile strength, and flexural modulus of elasticity as compared to previously known composites. In some embodiments, the present invention provides methods including the steps of providing cellulose nanofibrils, associating the cellulose nanofibrils with a maleic-anhydride (MA) copolymer to form a nanofibril-MA copolymer blend, preparing the nanofibril-MA copolymer blend for addition to a matrix polymer, and forming a composite by associating the nanofibril-MA copolymer blend with the matrix polymer, wherein the amount of cellulose nanofibrils in the composite is between 3% and 50% by weight of the composite.Type: GrantFiled: July 17, 2014Date of Patent: May 7, 2019Assignee: University of Maine System Board of TrusteesInventors: Douglas J. Gardner, Yousoo Han, Yucheng Peng
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Patent number: PP30473Abstract: A new cherry tree variety suitable for use as rootstock.Type: GrantFiled: October 31, 2016Date of Patent: May 7, 2019Assignee: Board of Trustees of Michigan State UniversityInventor: Amy Iezzoni