Abstract: An adaptive, any-fuel reciprocating engine using sensor feedback integration of high-speed optical sensors with real-time control loops to adaptively manage the electronic actuation schemes over a range of engine loads and fuels. The engine uses one or more optical sensors to collect specific types of gas property data via a spectroscopic technique to adaptively control various components within the engine.
Type:
Grant
Filed:
July 15, 2020
Date of Patent:
January 18, 2022
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Raymond Mitchell Spearrin, Tsu-Chin Tsao, Peter Sinsheimer
Abstract: Displacement devices comprise a stator and a moveable stage. The stator comprises a plurality of coils shaped to provide pluralities of generally linearly elongated coil traces in one or more layers. Layers of coils may overlap in the Z-direction. The moveable stage comprises a plurality of magnet arrays. Each magnet array may comprise a plurality of magnetization segments generally linearly elongated in a corresponding direction. Each magnetization segment has a magnetization direction generally orthogonal to the direction in which it is elongated and at least two of the magnetization directions are different from one another. One or more amplifiers may be connected to selectively drive current in the coil traces and to thereby effect relative movement between the stator and the moveable stage.
Abstract: The present invention belongs to the field of pharmaceutical technology, specifically disclosing thiazolopyrimidine compounds with the general formulas I and II. Also including theirs polycrystalline and eutectic, prodrugs and derivatives with same biologically functional, methods for their preparation, and compositions containing one or more of these compounds in the drugs application of treatment and prevention of human immunodeficiency virus.
Abstract: Methods for classification of microblogs using semi-supervised open domain targeted sentiment classification. A hidden Markov model support vector machine (SVM HMM) is trained with a training dataset combined with discrete features. A portion of the training dataset is clustered by k-means clustering to generate cluster IDs which are normalized and combined with the discrete features. After formatting, the combined dataset is applied to the SVM HMM and the C parameter, which is optimized by calculating a zero-one error at each iteration. The open domain targeted sentiment classification methods uses less labelled data than previous sentiment analysis techniques, thus decreasing processing costs. Additionally, a supervised learning model for improving the accuracy of open domain targeted sentiment classification is presented using an SVM HMM.
Type:
Grant
Filed:
October 11, 2019
Date of Patent:
January 18, 2022
Assignee:
King Fahd University of Petroleum and Minerals
Abstract: A low specific on-resistance (Ron,sp) power semiconductor device includes a power device and a transient voltage suppressor (TVS); wherein the power device comprises a gate electrode, a drain electrode, a bulk electrode, a source electrode and a parasitic body diode, the bulk electrode and the source electrode are shorted, the TVS comprises an anode electrode and a cathode electrode, the drain electrode of the power device and the anode electrode of the TVS are connected by a first metal to form a high-voltage terminal electrode, the source electrode of the power device and the cathode electrode of the TVS are connected by a second metal to form a low-voltage terminal electrode.
Type:
Grant
Filed:
May 19, 2020
Date of Patent:
January 18, 2022
Assignee:
UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA
Inventors:
Ming Qiao, Longfei Liang, Yilei Lyu, Zhao Qi, Bo Zhang
Abstract: An apparatus for selectively detecting an anion in a medium and/or selectively measuring the concentration of an anion in a medium. The apparatus comprises at least one sensor and a conductive polymer film and is configured such that dielectric and/or electric property changes of the conductive polymer film can be detected by the sensor when the conductive polymer film is in hydraulic contact with the medium or after it has been in hydraulic contact with the medium. Methods of selectively detecting an anion in a medium and/or selectively determining a concentration of an anion in a medium are also provided.
Type:
Grant
Filed:
October 13, 2017
Date of Patent:
January 18, 2022
Assignees:
University of South Australia, Sentek Pty Ltd
Inventors:
Drew Raymond Evans, Sam Rudd, Peter Buss, Michael Reginald Dalton, Michael Robert Portmann
Abstract: A multi-degree-of-freedom (Multi-DOF) 3D printing device includes a printer mechanism, a rotatable platform, a visual inspection system, and a control system. The printing mechanism includes a print head. The printing mechanism and the rotatable platform are combined to have three degrees of freedom of translation, and the rotatable platform has two degrees of freedom of rotation. The visual inspection system includes a camera mounted to nearby the print head and the relative position of camera and print head remains constant. The control system is configured to implement the printing process. The model is decomposed into several components, each of which could be printed in a single direction. After one component is printed out, the platform is then rotated so that the cutting plane for the component will be printed is horizontal.
Type:
Grant
Filed:
June 19, 2019
Date of Patent:
January 18, 2022
Assignees:
Beijing University of Technology, Beijing Cloud Profound Technologies Company Limited
Abstract: Methods for classifying and measuring orientations of objects, as nonlimiting examples, implants utilizing two-dimensional radiographs. One such method determines a three-dimensional orientation of an object based on its area projected onto a two-dimensional image and known or measured geometry. Another such method provides an automated solution to computationally determine the orientation and characterizing features of an implant based on two-dimensional radiographs. Orientations and characteristics of one or more objects in the vicinity of an object of interest may also be determined.
Type:
Grant
Filed:
August 8, 2019
Date of Patent:
January 18, 2022
Assignee:
Loyola University Chicago
Inventors:
Michael Patrick Murphy, Cameron James Killen, Karen Wu
Abstract: A large area surveillance method is based on weighted double deep Q-learning. A robot which of Q-value table including a QA-value table and QB-value table is provided, an unidentified object enters a large space to trigger the robot, and the robot perceives a current state s and determines whether the current state s is a target state, if yes, the robot reaches a next state and monitors the unidentified object, and if not, the robot reaches a next state, obtains a reward value according to the next state, selectively updates a QA-value or QB-value with equal probability, and then updates a Q-value until convergence to obtain an optimal surveillance strategy. The problems of a limited surveillance area and camera capacity are resolved, and the synchronization of multiple cameras doesn't need to be considered, and thus the cost is reduced. A large area surveillance robot is also disclosed.
Abstract: Mithramycin side chain carboxylic acid (MTM-SA) derivative are provided, which include a substituted amino acid derivative, a substituted amino acid dipeptide derivative, or an unsubstituted dipeptide derivative. The MTM-SA derivatives are useful for treatment of cancer or neuro-diseases associated with an aberrant erythroblast transformation-specific transcription factor. Unique MTM-SA derivatives have increased selectively toward ETS transcription factor.
Type:
Grant
Filed:
September 5, 2018
Date of Patent:
January 18, 2022
Assignee:
University of Kentucky Research Foundation
Abstract: An imaging method and device, the method comprising: acquiring, at a specified imaging time, a pulse sequence in a time period before the specified imaging time, with regard to each pixel of a plurality of pixels; calculating a pixel value of the pixel according to the pulse sequence; obtaining a display image at the specified imaging time according to a space arrangement of the pixels, in accordance with pixel values of the plurality of pixels at the specified imaging time.
Abstract: A method for cloning an exon into a plasmid vector. Exons related to prostate cancer (PVT1 exon 9, PVT1 exon 4A or PVT1 exon 4B) and miRNAs (miR-1205 or miR-1207-3p) are transformed into the plasmid vector. The cloned exons or miRNAs are linearized and their concentrations quantified. Serial dilutions in conjunction with spectroscopy permit the construction of a standard curve that permits absolute quantification of the exons or miRNAs in a biological sample from a patient.
Type:
Grant
Filed:
March 18, 2019
Date of Patent:
January 18, 2022
Assignee:
Research Foundation of the City University of New York
Abstract: Methods, systems, and computer readable media to detect and model a brain tumor in an electronic image and to predict features of the brain tumor based on the model. The method can include classifying one or more magnetic resonance imaging (MRI) images of a brain into one or more of one or more tumorous images containing an image of a tumor or one or more non-tumorous images, wherein the classification is performed using a deep learning CNN system. The method can also include segmenting a tumor region from one of the one or more tumorous images. The segmenting can include a neighboring Fuzzy C-Means (FCM) process. The method can further include classifying the segmented tumor region into one of four classes of brain tumor types. The segmented tumor region is classified as a particular brain tumor type using the deep learning CNN system. The method can also include reconstructing a 3D model of the tumor region and measuring one or more of a location of the tumor, a shape of the tumor, or a volume of the tumor.
Abstract: The subject invention pertains to a modified lantibiotic containing an intact cysteine at the C-terminus, particularly, a cysteine that is not decarboxylated and that contains a free carboxyl group. Derivatives of the modified lantibiotic comprising a moiety conjugated to the carboxyl group of the terminal cysteine are also provided. A bacterium that produces a modified lantibiotic having an intact cysteine at the C-terminus are also provided, wherein the bacterium is genetically modified to inactivate a gene that encodes a decarboxylase enzyme that decarboxylates the cysteine at the C-terminus of a precursor lantibiotic. Methods of producing a modified lantibiotic having an intact cysteine at the C-terminus by culturing a bacterium that synthesizes the modified lantibiotic and purifying the lantibiotic are also provided. Mutants of lantibiotics, particularly, mutacin 1140 having higher anti-bacterial activity or higher bacterial expression compared to mutacin 1140 are also provided.
Abstract: Provided is a molecular assembly (for example, a polymeric micelle nanoparticle) which is capable of efficiently encapsulating a fat-soluble drug. A molecular assembly comprising: an amphiphilic block polymer A1 comprising a hydrophilic block having a sarcosine unit and a hydrophobic block having a lactic acid unit; a hydrophobic polymer A2 having a lactic acid unit; a fatty acid triglyceride; and a fat-soluble drug. Examples of the fat-soluble drug include miriplatin.
Type:
Grant
Filed:
September 20, 2016
Date of Patent:
January 18, 2022
Assignees:
SHIMADZU CORPORATION, KYOTO UNIVERSITY
Inventors:
Isao Hara, Eiichi Ozeki, Shunsaku Kimura, Takayuki Sato
Abstract: Described are devices, systems and techniques for implementing atomic memory objects in a multi-writer, multi-reader setting. In an embodiment, the devices, systems and techniques use maximum distance separable (MDS) codes, and may be specifically designed to optimize a total storage cost for a given fault-tolerance requirement. Also described is an embodiment to handle the case where some of the servers can return erroneous coded elements during a read operation.
Type:
Grant
Filed:
November 23, 2020
Date of Patent:
January 18, 2022
Assignees:
Massachusetts Institute of Technology, Northeastern University, University of Connecticut
Inventors:
Muriel Medard, Kishori Mohan Konwar, Prakash Narayana Moorthy, Nancy Ann Lynch, Erez Kantor, Alexander Allister Schwarzmann
Abstract: Embodiments described herein are directed to wireless power transfer systems, which can include a vertical pair of an inner and an outer coupling capacitors. According to certain embodiments, one plate from each of the outer coupling capacitor at least in part overlaps one plate of the inner coupling capacitor on a primary side and another plate from the outer coupling capacitor at least partially overlaps another plate of the inner coupling capacitor on a secondary side. Each plate of the outer coupling capacitor has a larger area than each plate of the inner coupling capacitor. Further, a power transfer unit is included and configured to transfer power capacitively through the vertical pair of coupling capacitors, where the power transfer unit can include first and second inductors coupled to each plate of the outer coupling capacitor, respectively.
Type:
Grant
Filed:
March 22, 2017
Date of Patent:
January 18, 2022
Assignee:
San Diego State University Research Foundation
Abstract: An electrolyte solution for a potassium ion battery or a potassium ion capacitor, the electrolyte solution comprising at least one potassium salt compound selected from the group consisting of potassium bis(trifluoromethanesulfonyl)amide and potassium bis(fluorosulfonyl)amide and at least one solvent selected from the group consisting of ethylene glycol dimethyl ether, diethylene glycol dimethyl ether, triethylene glycol dimethyl ether, tetraethylene glycol dimethyl ether, pentaethylene glycol dimethyl ether, ethylene carbonate, and propylene carbonate, in which a concentration of the potassium salt compound in the electrolyte solution is from 1.5 mol/kg to 12.0 mol/kg.
Abstract: A cell sorting device is characterized by including: a main flow channel (14) through which a liquid containing a row of cells including a target cell flows, and in which a cell separation area for separating the target cell from the row of cells is provided at a halfway position in a flow direction, the main flow channel being formed in a substrate (12); a selection flow channel (16) into which the target cell is pushed out from the main flow channel, the selection flow channel being formed in the substrate so as to branch from the main flow channel downstream of the cell separation area; a sub flow channel (18) through which a separating liquid flows, the separating liquid being for separating the target cell from the row of cells and pushing out the target cell into the selection flow channel, the sub flow channel being formed in the substrate so as to intersect with the main flow channel in the cell separation area; a pair of liquid flow generating members (22) for generating a liquid flow of the separati
Type:
Grant
Filed:
March 6, 2017
Date of Patent:
January 18, 2022
Assignee:
NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY