Abstract: A dynamically obfuscated scan chain (DOSC) includes a control module designed to control memory loading, a linear feedback shift register (LFSR), a dynamic Obfuscation Key generator configured to use LFSR to generate a ?-bit protected Obfuscation Key, in order to confuse and change the test data into an output scan vectors when the Obfuscation Key update is triggered. The DOSC also includes a shadow chain, configured to input the ?-bit protected Obfuscation Key generated by the LFSR, and output k??×??-bit protected Obfuscation Keys, and obfuscated scan chains. The DOSC operating method includes: loading control vectors to LFSR from control module during initialization; generating the Obfuscation Key at an output of the LFSR; generating the Obfuscation Key bit by bit based at least in part on the shadow chain and the Obfuscation Key during a first scan clock after reset in order to confuse test patterns.

Abstract: Particles, compositions, and methods that aid particle transport in mucus are provided. The particles, compositions, and methods may be used, in some instances, for ophthalmic and/or other applications. In some embodiments, the compositions and methods may involve modifying the surface coatings of particles, such as particles of pharmaceutical agents that have a low aqueous solubility. Such compositions and methods can be used to achieve efficient transport of particles of pharmaceutical agents though mucus barriers in the body for a wide spectrum of applications, including drug delivery, imaging, and diagnostic applications. In certain embodiments, a pharmaceutical composition including such particles is well-suited for ophthalmic applications, and may be used for delivering pharmaceutical agents to the front of the eye and/or the back of the eye.

Abstract: Provided herein are, inter alia, compositions and methods for identifying and using agents capable of inhibiting myofibroblast transition as well as methods for treating diseases associated with the same in a subject in need thereof.

Abstract: Provided herein are analytical methods utilizing a self-limiting catalytic reaction, and compositions and kits useful therefore. In one aspect the method is used to quantify Pd, and in another, the method is a horseradish peroxidase assay.

Abstract: The present invention provides a method for determining a treatment procedure for breast cancer, a method of predicting a likelihood of success in treating breast cancer, and a method for selecting an endocrine therapy agent for treating breast cancer. In particular, methods of the present invention rely on the amount of androgen receptor (AR) and estrogen receptor (ER) in a tissue sample.

Abstract: Systems and methods for measuring a curvature radius of a sample. The methods comprise: emitting a light beam from a laser source in a direction towards a beam expander; expanding a size of the light beam emitted from the laser source to create a broad laser beam; reflecting the broad laser beam off of a curved surface of the sample; creating a plurality of non-parallel laser beams by passing the reflected broad laser beam through a grating mask or a biprism; using the plurality of non-parallel laser beams to create an interference pattern at a camera image sensor; capturing a first image by the camera image sensor; and processing the first image by an image processing device to determine the curvature radius of the sample.

Abstract: Non-contact methods and systems are disclosed for estimating an in-bed human pose. The method includes the steps of: (a) capturing thermal imaging data of a human subject lying on a bed using a long wavelength infrared camera positioned above the human subject; (b) transmitting the thermal imaging data to a computer system; and (c) processing the thermal imaging data by the computer system using a model to estimate the pose of the human subject, the model comprising a machine learning inference model trained on a training dataset of a plurality of in-bed human poses.

Abstract: A flexible electronics assembly includes a single-piece substrate having two regions of rigidity separated by a localized region of flexibility. The localized region of flexibility has a lower rigidity than the two regions of rigidity. The two regions of rigidity are angularly deflectable from a planar configuration of the single-piece substrate to a non-planar configuration of the single-piece substrate by hinging action of the localized region of flexibility. At least one electronic component is mounted on at least one of the two regions of rigidity.

Abstract: Approaches presented herein enable implementation of augmented reality in a smart glasses device. More specifically, two-dimensional (2-D) image data of a real-world object is collected from a 2-D camera of the smart glasses device. From the collected 2-D image data, 2-D coordinate data is generated. Based on location and rotation data of the smart glasses device and 2-D depth information from a viewing angle of the smart glasses device, three-dimensional (3-D) coordinates are generated from the generated 2-D coordinate data. An augmented object is displayed, on a holographic display of the smart glasses device, at an apparent location of the real-world object utilizing the 3-D coordinates.

Abstract: The disclosure relates to use of a triple formulation comprising a histone deacetylase, a cyclodextrin and polyethylene glycol or propylene glycol, and in the treatment and management of chronic pain.

Abstract: A microscopy method includes a trained deep neural network that is executed by software using one or more processors of a computing device, the trained deep neural network trained with a training set of images comprising co-registered pairs of high-resolution microscopy images or image patches of a sample and their corresponding low-resolution microscopy images or image patches of the same sample. A microscopy input image of a sample to be imaged is input to the trained deep neural network which rapidly outputs an output image of the sample, the output image having improved one or more of spatial resolution, depth-of-field, signal-to-noise ratio, and/or image contrast.

Abstract: Disclosed are a universal alpha-olefin polymerization industrial catalyst, and an application thereof, specifically an industrial production catalyst which consists of (A) a solid catalyst component, (B) a cocatalyst organoaluminium compound and (C) an external electron donor compound, and is used for various alpha-olefin polymerization or copolymerization processes. The solid catalyst component (A) is prepared from a dibutyl phthalate or diisobutyl phthalate and 9,9-bis(methoxymethyl)fluorene composite internal electron donor. A hydrocarbyl alkoxy silicon, an organic acid ester or a hydrocarbyl alkoxy silicon and organic acid ester composite acts as the external electron donor component (C). The solid catalyst component (A), the cocatalyst organoaluminium compound (B) and the external electron donor compound (C) are used together in industrial devices for various alpha-olefin polymerization or copolymerization processes to produce new grades of poly-alpha-olefins.

Abstract: An implantable device comprising a substrate capable of capturing an intraocular target molecule and to methods of use thereof. The substrate may be capable of capturing a target molecule present in the eye and/or from fluid of the eye (e.g., an intraocular target molecule). In some embodiments, the substrate has a relatively high affinity for a target molecule.

Abstract: Provided is a method of genetically incorporating an L-dihydroxyphenylalanine in a target protein.

Abstract: The present application provides a low carbon martensitic high temperature strength steel and a preparation method thereof, wherein the chemical composition of the low carbon martensitic high temperature strength steel are: C: 0.10-0.25 wt %, Cr: 10.0-13.0 wt %, Ni: 2.0-3.2 wt %, Mo: 1.50-2.50 wt %, Si?0.60 wt %, Mn?0.60 wt %, W: 0.4-0.8 wt %, V: 0.1-0.5 wt %, Co: 0.3-0.6 wt %, Al: 0.3-1.0 wt %, Nb: 0.01-0.2 wt %, and a balance of Fe. The high temperature strength steel of the present application achieves high strength at high temperature by simultaneously precipitating both nano-coherent carbides and intermetallic compounds. It has an excellent toughness, and can be used for certain structural parts under special working conditions, such as aero-engines to increase its service life and service temperature.

Abstract: The disclosure relates to metal nanoparticle compositions and their methods of formation and use, in particular gold nanoparticles (AuNP) and gold-coated magnetic nanoparticles. Compositions according to the disclosure include aqueous suspensions of metal nanoparticles that are stabilized with one or more carbohydrate capping agents and/or that are functionalized with one or more binding pair members for capture/detection of a target analyte. The nanoparticle suspensions are stable for extended periods and can be functionalized as desired at a later point in time, typically prior to use in an assay for the detection of a target biological analyte. The stable nanoparticle suspension can be formed by the aqueous reduction of oxidized metal precursors at non-acidic pH values in the presence of a carbohydrate-based capping agent such as dextrin or other oligosaccharides.

Abstract: Provided herein are methods of treatment of psychiatric disorders requiring treatment with an antipsychotic drug, such as schizophrenia or schizoaffective disorder, comprising administration of both the antipsychotic drug and a W. somnifera plant part, extract, chemical constituent(s) thereof, or a derivative thereof to treat symptoms of the psychiatric disorder. Treatment is typically continued for at least four weeks. A combination dosage form comprising both the antipsychotic drug and the W. somnifera plant part, extract, chemical constituent(s) thereof, or a derivative thereof in amounts effective to treat the psychiatric disorder.

Abstract: The present disclosure discloses a preparation method for 4-phenylthio-benzenethiol. The preparation method comprises the following steps: subjecting phenyl sulfide as a raw material to a halogenation reaction to obtain 4-halophenyl sulfide; subjecting the 4-halophenyl sulfide to a sulfhydrylation reaction to obtain a 4-phenylthio-phenylthiolate; and subjecting the 4-phenylthio-phenylthiolate to acidification. The preparation method of the present disclosure avoids the use of materials such as thiophenol which pollutes the environment, and realizes efficient recycling of the reaction materials, solvents, water and the like. The preparation method of the present disclosure is a green process for the synthesis of 4-phenylthio-phenylthiol without organic waste, waste acid and waste water discharge.

Abstract: Disclosed herein are an at least quaternary composition that comprises at least two donor components and at least two low-molecular-weight fullerene acceptor components and is able to allow for superior photovoltaic performance over a long period of time, and an organic solve cell comprising an active layer formed thereof.

Abstract: The application discloses a light scattering parameter measurement system and its measurement method. Dual-frequency scattering interference technology is adopted to obtain distributed measurement of Rayleigh scattering parameters in an optical fiber. The Rayleigh scattering coefficient r and phase retardance ? are modulated on different components of the interference signal respectively by using the dual-frequency interference technology. The Rayleigh scattering coefficient r and phase retardance ? can be decoupled by simple filtering, to obtain separate measurements. A linear stretch is applied to the optical fiber under test, to add uniform phase change signals at all positions of the optical fiber under test. As a result, the term containing only Rayleigh scattering coefficient r can be extracted by low-pass filtering. The direct measurement of Rayleigh scattering parameters is of great significance to fundamental and application researches related to Rayleigh scattering of optical fiber.