Patents Assigned to University
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Patent number: 10314250Abstract: The present invention discloses a bag packing mechanism for mushroom cultivation, which comprises two clamping seats, transport means, air duct, pumping means and push rod. Transport means supply collar. Air duct descends through the collar and extends into a bag from the opening of the bag, the two clamping seats clamp the top portion of the bag to close to the outer periphery of the air duct, the pumping means sucks the top portion, the two clamping seats open, the push rod is lowered to push down the collar to put on the top portion, the pumping means blow to open the top portion, the push rod is further lowered to fold the top portion down, the air duct and putter rise, and then complete the automation of packaging job.Type: GrantFiled: December 28, 2015Date of Patent: June 11, 2019Assignee: National Formosa UniversityInventors: Rong-Yuan Jou, Chih-Jen Lee
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Patent number: 10317414Abstract: Methods of assessing the risk of cardiovascular disease in a subject by detecting the level of at least one metabolite in a sample from the subject are disclosed herein. The level of the metabolite is indicative of the risk of cardiovascular disease in the subject. The metabolites may be acylcarnitines, amino acids, ketones, free fatty acids or hydroxybutyrate. The cardiovascular disease may be risk of a cardiovascular event, presence of coronary artery disease or risk of development of coronary artery disease.Type: GrantFiled: March 10, 2016Date of Patent: June 11, 2019Assignee: Duke UniversityInventors: Svati H. Shah, Christopher B. Newgard, William E. Kraus, Elizabeth R. Hauser, Geoffrey S. Ginsburg, L. Kristin Newby
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Patent number: 10317342Abstract: Novel and advantageous systems and methods for performing nanometer-scale microscopy using graphene plasmons (GPs) are provided. Sub-diffraction microscopy can be achieved, taking advantage of the extremely small plasmon wavelength and low dissipation of GPs. Nanometer-scale resolution can be obtained under very weak light intensity, which is especially important in the imaging of biological systems.Type: GrantFiled: July 1, 2016Date of Patent: June 11, 2019Assignees: The Texas A&M University System, The National Centre for Applied Physics, KACSTInventors: Muhammad Suhail Zubairy, Mohammad D. Al-Amri, Xiaodong Zeng
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Patent number: 10316432Abstract: Provided herein are methods for the manufacture of fibers from solution-phase peptide-based polymers by electrospinning, and compositions produced thereby. In particular embodiments, various embodiments provide electrospinning supramolecular fibers from low concentration peptide amphiphile filaments.Type: GrantFiled: September 30, 2014Date of Patent: June 11, 2019Assignee: Northwestern UniversityInventors: Alok S. Tayi, E. Thomas Pashuck, III, Samuel I. Stupp
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Patent number: 10314917Abstract: Sub-100 micron multimodal nanoparticles have four main components: 1) a target element (peptides, lipids, antibodies, small molecules, etc.) that can selectively bind to cells, tissues, or organs of the body; 2) a diagnostic agent such as a fluorophore or NMR contrast agent that allows visualization of nanoparticles at the site of delivery and/or a therapeutic or prophylactic agent; 3) an outside “stealth” layer that allows the particles to evade recognition by immune system components and increase particle circulation half-life; and 4) a biodegradable polymeric material, forming an inner core which can carry therapeutics and release the payloads at a sustained rate after systemic, intraperitoneal, or mucosal administration. These particles possess excellent stability, high loading efficiency, multiple agent encapsulation, targeting and imaging. They are targeted to sites of, or associated with, inflammation caused by a disease, disorder; trauma, chemotherapy or radiation.Type: GrantFiled: March 17, 2014Date of Patent: June 11, 2019Assignees: The Brigham and Women's Hospital, Inc., Massachusetts Institute of Technology, The Trustees of Columbia University in the City of New yorkInventors: Omid C. Farokhzad, Xueqing Zhang, Xiaoyang Xu, Nazila Kamaly, Mingming Ma, Pedro M. Valencia, Robert S. Langer, Ira Tabas, Gabrielle Beth Fredman
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Patent number: 10314483Abstract: The present invention provides for very fast detection of gaze direction using retro-reflected light from the ocular fundus that is cost-efficient, small, and portable. These eye trackers are useful in many areas of science and technology, including but not limited to remote control, space, defense, medical and psycho-physiological applications, to identify for example subtle neurologic deficits that occur with cerebellar or vestibular disorders, Parkinson's disease, strokes, traumatic brain injury, possible concussions during sports matches, some forms of reading disability, or simply fatigue or inebriation. In ophthalmology, with two such devices operating simultaneously, the variability of relative eye alignment over time can be measured, without requiring individual calibration, and without requiring fixation on a specified target, ideal for use with small children.Type: GrantFiled: March 1, 2017Date of Patent: June 11, 2019Assignee: The Johns Hopkins UniversityInventors: Boris I. Gramatikov, David L. Guyton
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Patent number: 10316246Abstract: The present invention discloses a method of preparing polymeric photoluminescent dots in water using inexpensive non-conjugated polymers. The resulting polymeric photoluminescent dots display the following properties: excellent water dispersibility, low toxicity, high absorptivity, good photo-stability and high quantum yield. The photoluminescent properties are not influenced by aggregation-caused quenching effect. The method is amenable to scale-up and is environmentally friendly.Type: GrantFiled: May 31, 2017Date of Patent: June 11, 2019Assignee: The Hong Kong Polytechnic UniversityInventors: Pei Li, Yuan Yao, Dechao Niu
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Patent number: 10315951Abstract: A pillar-nanoantenna array structure is fabricated with a substrate to which pairs of pillars are coupled, where the pillars are characterized either by a thermal conductance less than 0.1 ?W/deg or by transparency and a height exceeding thickness by at least a factor of two. Metallic caps atop a neighboring pair of pillars are separated by no more than 50 nm. An image-capture structure may be formed by modifying reflectance of a portion of the structure by heating of the portion by electromagnetic radiation. The array may be plastically deformed by raster scanning an electron beam across the array, exciting plasmon modes in the conducting particles thereby inducing a gradient force between neighboring conducting particles, and deforming neighboring pillars in such a manner as to vary the spacing separating neighboring conducting particles. A technique of plasmon-assisted etching provides for fabricating specified planar pattern of metal outside a cleanroom environment.Type: GrantFiled: June 14, 2016Date of Patent: June 11, 2019Assignee: The Board of Trustees of the University of IllinoisInventors: Kimani C. Toussaint, Brian J. Roxworthy, Abdul Monnag Bhuiya
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Patent number: 10315128Abstract: A dephlegmator is provided comprising two stages connected in series wherein a first stage includes an air-cooled reflux condenser and a second stage includes a generally horizontal tube bundle of smooth or finned tubes that can be operated selectively in either an air-cooled (dry) mode under selected ambient conditions or in a wet evaporatively cooled mode under other selected ambient conditions including that of elevated ambient temperature. Spray nozzles may be installed above the tube bundle whereby water can be sprayed onto the tube bundle. One or more collection troughs are preferably provided beneath the tube bundle for collecting run-off water and enabling recycling of excess deluge water. Preferably, the tube bundle comprises at least two, and preferably three groups of tubes communicating with each other wherein the second group of tubes has appreciably fewer tubes in it than the first group of tubes and any third group of tubes has appreciably fewer tubes in it than the second group of tubes.Type: GrantFiled: July 10, 2012Date of Patent: June 11, 2019Assignee: Stellenbosch UniversityInventors: Hanno Carl Rudolf Reuter, Detlev G. Kröger
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Patent number: 10319188Abstract: Provided is a game system which performs control so as to allow a donation to be made by using a value (points) other than a value which a user can directly obtain as an outcome of a game. A donation management server 40 stores settings related to donations made by the user in a donation setting information table 421 and for example, when the user performs a cashing-out operation on a slot machine 1010, performs control so as to automatically make the donation by subtracting points corresponding to a specified donation amount from points stored so as to be associated with a user card based on the above-mentioned settings made by the user.Type: GrantFiled: March 28, 2017Date of Patent: June 11, 2019Assignee: Universal Entertainment CorporationInventor: Kengo Takeda
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Patent number: 10315169Abstract: Disclosed are fouling resistant filtration membranes comprising a polymeric thin-film membrane comprising a surface. Also disclosed are methods of modifying thin-film filtration membranes, thereby improving, for example, the anti-fouling properties of the membranes. Also disclosed are methods of purifying water using the disclosed membranes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: April 28, 2017Date of Patent: June 11, 2019Assignee: The Regents of the University of CaliforniaInventors: Eric M. V. Hoek, Richard B. Kaner, Brian T. McVerry
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Patent number: 10316014Abstract: This disclosure relates generally to the facile and selective mono-perfluoro and -polyfluoroarylation of Meldrum's acid to generate a versatile synthon for highly fluorinated alpha-phenyl acetic acid derivatives which provide straightforward access to fluorinated building blocks. The reaction takes place quickly and all products were isolated without the need for chromatography. An embodiment provides an alternative strategy to access alpha-arylated Meldrum's acids which avoids the need for aryl-Pb(IV) salts or diaryliodonium salts and provides access to the tertiary product which was not previously synthetically accessible. The synthetic versatility and utility of the Meldrum's acid products is demonstrated by subjecting the products to several derivatizations of the Meldrum's acid products as well as photocatalytic hydrodefluorination which provide access to difficult but valuable synthetic targets such as multifluorinated aromatics.Type: GrantFiled: August 31, 2015Date of Patent: June 11, 2019Assignee: The Board of Regents for Oklahoma State UniversityInventors: Jimmie Dean Weaver, Sameera Senaweera
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Patent number: 10314835Abstract: This disclosure relates to managing conditioned fear and conditions induced by experiencing or witnessing an extreme traumatic event using neurokinin receptor antagonists. In certain embodiments, the disclosure relates to methods of treating or preventing conditioned fear comprising administering an effective about neurokinin 3 receptor antagonist to a subject in need thereof. In certain embodiments, the subject is diagnosed with Post-Traumatic Stress Disorder. In certain embodiments, the neurokinin 3 receptor antagonist is (R)—N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine or salts thereof.Type: GrantFiled: June 25, 2015Date of Patent: June 11, 2019Assignee: Emory UniversityInventors: Kerry J. Ressler, Raul Andero Gali
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Patent number: 10314708Abstract: An adaptively positioned mitral valve closure plate blocker for repairing mitral regurgitation, comprising a suture and shaping ring (4.1) sutured on a mitral ring (2.1) and a closure plate (4.2); the closing plate (4.2) comprises a tongue-shaped plate and a strut (4.3) located at the top of the tongue-shaped plate and connected to the suture and shaping ring; the closing plate (4.2) can be connected to the suture and shaping ring (4.1), being capable of flapping back and forth and twisting left and right. The suture and shaping ring is sutured on the valve ring (2.1) of the mitral valve (2) of a patient in a thoracotomy and open heart surgery, thus shaping the disease expanded mitral ring (2.1), and supporting the closing plate (4.2); when a heart contracts and valve leaflets close, the closing plate (4.2) flaps and twists depending on the position of a regurgitation opening at the free edge of the valve leaflets to realize adaptive positioning of the closing plate (4.2), so that the closing plate (4.Type: GrantFiled: July 9, 2014Date of Patent: June 11, 2019Assignee: Jiangsu UniversityInventors: Zhaoming He, Kailiang Zhang, Teng Jing
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Patent number: 10320303Abstract: A system and a method offset the effect of a reduced load current on a power factor controller connected to a DC-to-DC converter having a switching DC-to-AC inverter driving an output rectifier that produces the load current. A frequency-dependent load impedance is coupled to the output of the inverter. The frequency-dependent load impedance is configured to have a first impedance when the inverter is operating at the minimum operating frequency. The frequency-dependent load impedance has a second impedance when the inverter is operating at the maximum operating frequency. The second impedance is lower than the first impedance and produces a dummy load current that is added to the actual load current to provide a sufficient total load current to cause the power factor controller to operate in a continuous mode even when the actual load current is insufficient to cause the power factor controller to operate in a continuous mode.Type: GrantFiled: September 4, 2018Date of Patent: June 11, 2019Assignee: Universal Lighting Technologies, IncInventor: Wei Xiong
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Patent number: 10316294Abstract: This invention provides highly attenuated influenza viruses and vaccines. The attenuated viruses and vaccines proliferate well and have high safety factors. The attenuated viruses providing protective immunity from challenge by virus of the same subtype, as well as cross protection against heterologous viruses.Type: GrantFiled: March 15, 2014Date of Patent: June 11, 2019Assignee: The Research Foundation for The State University of New YorkInventors: Steffen Mueller, Eckard Wimmer, Bruce Futcher, Steven Skiena, Chen Yang
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Patent number: 10314548Abstract: Methods and systems for performing T1 mapping. T1 samples are obtained from an acquisition including one or more inversion groupings. The acquisition may be designed to result in incomplete tissue magnetization recovery between inversion groupings. The acquisition may be designed for the use of non-uniform, non-180° preparatory pulses. The method may also include the combined use of data from different inversion groupings. A model is used in which fit parameters are variable dependent on the inversion grouping.Type: GrantFiled: September 24, 2015Date of Patent: June 11, 2019Assignee: University Health NetworkInventors: Marshall Stephen Sussman, Bernd Juergen Wintersperger, Kai-Ho Fok, Issac Yiqun Yang
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Patent number: 10316348Abstract: Methods and devices for monitoring the viability of a biofilm comprising Pseudomonas Aeruginosa bacteria are provided by detecting pyocyanin. The invention relates to electrochemical methods and devices that offer a simple and inexpensive alternative for immediate identification of bacterial infection due to the presence of Pseudomonas aeruginosa. In some embodiments, an inexpensive, disposable electrochemical sensor can be used to rapidly screen for the presence of P. aeruginosa in clinical wound effluent samples.Type: GrantFiled: September 16, 2015Date of Patent: June 11, 2019Assignee: Northeastern UniversityInventors: Edgar D. Goluch, Hunter J. Sismaet, Thaddaeus A. Webster
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Patent number: 10317324Abstract: A specimen testing system has holders that hold a specimen for testing. The holders brace the specimen so that a load may be applied. A load applicator applies a load to the specimen at a location that is between the holders bracing the specimen. A user may adjust the load applicator until it applies the desired load to the specimen. If desired, a user may apply rotation to a specimen while it is experiencing a load by using a specimen rotation system. The user may continue to adjust the load applied to the specimen or continue to rotate the specimen during loading until the specimen fails.Type: GrantFiled: February 20, 2018Date of Patent: June 11, 2019Assignee: Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in HuntsvilleInventors: Kalob Ownby, Mark Creel, Jordan Fulmer, Matt Fulmer, Michael Henry, Dung Tuan Le, Melissa Lee, Derek Odom, Russ Walton, Jeffrey Evans
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Patent number: 10317892Abstract: A computer-implemented method for concurrent multi-user computer-aided manufacturing may include (1) receiving a tool path descriptor resulting from a tool path request on a local copy of a part model, (2) submitting the tool path descriptor to a server for application to a shared copy of the part model, (3) receiving, from the server, shared model data corresponding to the tool path descriptor, and (4) applying the shared model data to the local part model. Various other methods and systems are also disclosed.Type: GrantFiled: October 15, 2015Date of Patent: June 11, 2019Assignee: Brigham Young UniversityInventors: Andrew Priddis, W. Edward Red