Abstract: A system and method are provided for creating magnetic resonance (MR) images with reduced motion artifacts from the MR data from which the images are produced. The method includes selecting a candidate image from a plurality of candidate images reconstructed from the MR data. The method also includes registering the candidate image to a reference image, comparing the candidate image to a consistency map, and, based on comparing the candidate image using the consistency map, selecting a blending algorithm. The method also includes generating a blended image using the blending algorithm and the candidate image and repeating these steps for each candidate image. The method also includes performing a Fourier aggregation to generate a combined image and displaying the combined image with reduced motion artifacts compared to the plurality of candidate images.
Type:
Grant
Filed:
September 19, 2022
Date of Patent:
December 24, 2024
Assignees:
Regents of the University of Minnesota, Duke University
Inventors:
Oren Solomon, Noam Harel, Guillermo Sapiro, Edward Auerbach, Steen Moeller, Remi Patriat, Henry Braun, Tara Palnitkar
Abstract: A method and a device for encoding/decoding images are disclosed. The method for encoding images comprises the steps of: deriving a scan type of a residual signal for a current block according to whether or not the current block is a transform skip block; and applying the scan type to the residual signal for the current block, wherein the transform skip block is a block to which transform for the current block is not applied and is specified on the basis of information indicating whether or not transform for the current block is to be applied.
Type:
Grant
Filed:
January 27, 2023
Date of Patent:
December 24, 2024
Assignees:
Electronics and Telecommunications Research Institute, University-Industry cooperation Group Of Kyung Hee University
Inventors:
Hui Yong Kim, Sung Chang Lim, Jin Ho Lee, Jin Soo Choi, Jin Woong Kim, Gwang Hoon Park, Kyung Yong Kim
Abstract: The present application provides a system and method for realizing partial anammox advanced nitrogen and phosphorus removal through mainstream and sidestream biofilm cyclic alternating for a municipal wastewater treatment plant. The system includes three main component units: a mainstream zone (a), an advanced treatment zone (b) and a side stream zone (c). Advanced nitrogen and phosphorus removal of the entire system is realized through cyclic alternating of biofilms. In the mainstream zone (a), the main function of an anaerobic/anoxic zone is to perform heterotrophic denitrification nitrogen removal, and partial denitrification/anammox autotrophic nitrogen removal, and the main function of an oxic zone is to remove organic matter, perform aerobic phosphorus uptake, and complete a nitrification reaction.
Abstract: Provided herein are phosphatidylethanolamine (PE)-specific probes and methods of use thereof. In particular, the present invention provides conjugates of PE binding moieties with detectable markers, and methods of use thereof to detect and/or characterize PE within cells.
Abstract: The present invention relates to an ophthalmic knife and methods of its use for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. The device is configured for cutting the tissues within the eye, for example, a trabecular meshwork (TM).
Type:
Grant
Filed:
August 24, 2023
Date of Patent:
December 24, 2024
Assignees:
The Regents of the University of Colorado, a body corporate, New World Medical, Inc.
Inventors:
Malik Y. Kahook, Khalid Mansour, Suhail Abdullah, Eric Porteous, Vijay R. Balan
Abstract: An adaptive continuous-time linear equalizer (CTLE) includes a CTLE cell including input terminals and output terminals, a low-pass filter configured to respectively output low-band differential signals obtained by respectively low-pass filtering differential output signals, and an error amplifier configured to amplify a difference between the low-band differential signals and output the difference as a control voltage. The CTLE cell includes first and second transistors each including an input terminal and an output terminal and an offset compensator configured to adjust a potential difference between a supply voltage source and the output terminal according to the control voltage.
Type:
Grant
Filed:
November 25, 2022
Date of Patent:
December 24, 2024
Assignees:
Samsung Electronics Co., Ltd., University of Seoul Industry Cooperation Foundation
Abstract: A circulator includes a central circuit having a first superconducting island, a second superconducting island, a third superconducting island, and a central island, each in electrical communication with each other via a plurality of Josephson junctions.
Type:
Grant
Filed:
September 17, 2021
Date of Patent:
December 24, 2024
Assignees:
University of Maryland, College Park, Government of the United states of America, as represented by the Secretary of Commerce
Abstract: Methods for treating, reducing, ameliorating or inhibiting symptoms idiopathic pulmonary fibrosis (IPF) or interstitial pneumonia, comprising administering to a subject in need of an effective amount of a) multiple EGF-like-domains-9 (MEGF9) or a biologically active fragment thereof; b) uncoordinated receptor 5A (UNC5A) or a biologically active fragment thereof; c) dolichyl-phosphate beta-glucosyltransferase (ALG5) or a biologically active fragment thereof; d) a combination of two or three of a)-c); e) an antibody specifically binding to a); f) an antibody specifically binding to b); g) an antibody specifically binding to c); h) a combination of two or three of e)-g); or i) a combination of at least one of a)-c) and at least one of e)-g). Pharmaceutical compositions and processes for making and using the compositions are also disclosed.
Type:
Grant
Filed:
October 5, 2023
Date of Patent:
December 24, 2024
Assignee:
Board of Regents, The University of Texas System
Abstract: A detection device includes a photodiode, and a thin-film transistor coupled to the photodiode. The thin-film transistor includes a semiconductor layer between a light-blocking layer and the photodiode, and an electrode layer between the semiconductor layer and the photodiode, and the electric layer includes a source electrode and a drain electrode of the thin-film transistor. The source electrode extends to a position facing the light-blocking layer with the semiconductor layer interposed therebetween.
Type:
Grant
Filed:
October 13, 2021
Date of Patent:
December 24, 2024
Assignees:
Japan Display Inc., The University of Tokyo
Abstract: Provided are delocalized lipophilic cation (DLC) compounds and methods of using such compounds. Also provided are pharmaceutical compositions that include a DLC compound. Provided methods include methods of killing cells and methods of fluorescently labeling mitochondria by contacting the cells with a DLC compound of the present disclosure. Also provided are methods of imaging cell mitochondria, methods of determining whether a patient has a mitochondria related disease, and methods of treating a patient for a mitochondria related disease. Kits that include compounds of the present disclosure are also provided.
Type:
Grant
Filed:
January 10, 2020
Date of Patent:
December 24, 2024
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: The present invention relates to tobacco products from plants comprising mutated berberine bridge enzyme-like nucleic acids and the recessive nic1 and/or nic2 alleles and methods of making the same.
Type:
Grant
Filed:
January 8, 2021
Date of Patent:
December 24, 2024
Assignees:
North Carolina State University, 22ND CENTURY LIMITED, LLC
Inventors:
Ramsey S. Lewis, Ralph E. Dewey, Juan Sanchez Tamburrino
Abstract: A processor-implemented method of a neural network includes obtaining intermediate pooling results, respectively corresponding to sub-pooling kernels obtained by decomposing an original pooling kernel, by performing a pooling operation on input pixels included in a current window in an input feature map with the sub-pooling kernels, obtaining a final pooling result corresponding to the current window by post-processing the intermediate pooling results, and determining an output pixel value of an output feature map, based on the final pooling result, wherein the current window is determined according to the original pooling kernel having been slid, according to a raster scan order, in the input feature map.
Type:
Grant
Filed:
March 18, 2023
Date of Patent:
December 24, 2024
Assignees:
Samsung Electronics Co., Ltd., Seoul National University R&DB Foundation
Inventors:
Hyunsun Park, Soonhoi Ha, Donghyun Kang, Jintaek Kang
Abstract: Systems and methods for utilizing laboratory equipment in a hybrid reality environment or augmented virtual reality environment, are contemplated herein and include: at least one piece of laboratory equipment having at least one feature, wherein the at least one piece of laboratory equipment is tracked; a tracking module for tracking a position and an orientation of the at least one piece of tracked laboratory equipment; a virtual model, stored in a memory, comprising at least one 3-D virtual representation of the at least one feature of the at least one piece of laboratory equipment; and an experimentation module.
Type:
Grant
Filed:
July 3, 2023
Date of Patent:
December 24, 2024
Assignee:
The Trustees of the California State University
Inventors:
Kambiz Hamadani, Ali Ahmadinia, Xin Ye, Yuanyuan Jiang
Abstract: Provided herein are compositions and methods for detection of N6-methyladenosine (m6A) in ribonucleic acid (RNA). The provided compositions include fusion proteins that can be used to edit RNA and detect m6A residues. Also provided are nucleic acids, vectors, constructs, host cells, and transgenic animals that encode or express such fusions proteins.
Abstract: Multifunctional dendritic molecular probes that selectively detect Cu2+ ions via potentiometric and fluorometric techniques with low detection limits are disclosed. The selective and reversible binding of the molecules with the Cu2+ ion was used to make solid-state microsensors by incorporating the molecular probes into the carbon-based membranes as an ionophore for Cu (II).
Abstract: Human pluripotent stem cells are differentiated in vitro into forebrain subdomain structures, which are then fused to generate an integrated system for use in analysis, screening programs, and the like.
Type:
Grant
Filed:
February 14, 2022
Date of Patent:
December 24, 2024
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Jimena Andersen, Fikri Birey, Sergiu P. Pasca
Abstract: The present embodiment is an implantable device capable of controlling cochlear implant electrode insertion and positioning. The embodiment uses an implanted mechanical positioning unit to advance position and monitor an electrode array. The device can be controlled via an external controller to reposition or advance an electrode array at any point after implantation with no surgical re-intervention. A cochlear implant electrode array whose position can be advanced and modified over time to best fit a patient's evolving hearing pattern would improve functional outcomes and significantly expand the candidacy range for cochlear implantation to include patients with substantial residual hearing.
Abstract: A nano-positioning system for fine and coarse nano-positioning including at least one actuator, wherein the at least one actuator includes a high Curie temperature material and wherein the nano-positioning system is configured to apply a voltage to the at least one actuator to generate fine and/or coarse motion by the at least one actuator. The nano-positioning system being a stand-alone system, a scanning probe microscope, or an attachment to an existing microscope configured to perform a method of creepless nano-positioning that includes positioning a probe relative to a first area of a substrate using coarse stepping and interacting with the first area of the substrate using fine motion after less than 60 seconds of the positioning the probe. The movement of the scanning probe microscope is actuated by a high Curie temperature piezoelectric material that limits and/or eliminates creep, hysteresis and aging.
Type:
Grant
Filed:
August 31, 2020
Date of Patent:
December 24, 2024
Assignees:
National Research Council of Canada, The Governors of the University of Alberta
Inventors:
Robert A. Wolkow, Jason Pitters, Mark Salomons