Abstract: An overlapping and progressive forming method for a high-performance multi-element NiAl-based alloy tubular part, including: winding continuously flexible substrates of Ni and Al, and alloying coating continuously or selectively along a width direction or a rolling direction to obtain coated flexible substrates; winding continuously the coated flexible substrates on an outer surface of a core roller according to a sequence of Ni above and Al below to form a Ni/Al laminated structure having a plurality of layers with an outermost layer being a Ni layer, and consolidating with ultrasonic with assistance of a pulse current to combine the continuously wound flexible substrates into a laminated tube blank; and placing the laminated tube blank into a mold, applying a pulse current to both ends of the laminated tube blank for hot fluid high-pressure forming, and synthesizing in-situ to prepare the tubular part with assistance of the pulse current.

Abstract: Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process.

Abstract: Disclosed herein are crosslinked chondroitin sulfate particles crosslinked chondroitin sulfate particle polyelectrolytes. The particles are useful in drug delivery applications. The particles may be used to treat various conditions, including bacterial and fungal infections.

Abstract: The present disclosure provides a variable-rate spray control system based on an annular application structure and a tree canopy volume (TCV) calculation method thereof. The TCV calculation method includes: acquiring in real time, by using vertical/horizontal scanning two-dimensional (2D) LiDAR, point cloud data of a variable-rate sprayer in motion in an orchard environment; acquiring speed information of the variable-rate sprayer by using a speed sensor; dividing spraying regions according to an angle at which contacts of nozzles on an annular application structure are mutually spaced on an arc; filtering interferences by setting a threshold range, calculating a sector area of a tree canopy according to trunk distance information from the horizontal LiDAR and point cloud information from the vertical LiDAR within the threshold range, and calculating a TCV in combination with the information of the speed sensor and a scanning cycle of the vertical LiDAR.

Abstract: A system for monitoring a circuit, comprising a device under test, such as a power field effect transistor or capacitor, coupled to a power source and a signal source and configured to generate a power output using the signal source, a current output, a voltage output and an end of life detector coupled to the current output and the voltage output and configured to generate a first impedance as a function of the current output and the voltage output, to compare the first impedance to a second impedance and to generate an indicator if the first impedance exceeds the second impedance.

Abstract: A flow control system for three-dimensional (3D) control of fluids with a high spatiotemporal resolution using alternating magnetic fields is disclosed. This technology is applicable to many disciplines, including fluid dynamics, microfluidics, electrochemistry, metallurgy, and healthcare. In particular, the proposed technique can address challenging problems such as turbulence control, drag reduction, contactless mixing, crystal growth control, and targeted drug delivery.

Abstract: The present disclosure relates to an aluminum alloy material, and specifically to a weldable in-situ nano-strengthened rare-earth metal (REM)-containing aluminum alloy with high strength and toughness and a preparation method thereof. In the present disclosure, in-situ nano-ceramic particles and REMs simultaneously introduced into an Al—Zn—Mg alloy can effectively refine the grains and significantly improve the strength and toughness of the alloy; and REM-containing nano-precipitated phases and in-situ nanoparticles distributed in the grains or at grain boundaries can also significantly increase a recrystallization temperature of the alloy, effectively inhibit the dynamic recovery, reduce the re-dissolution of alloying elements, and improve the weldability of the alloy.

Abstract: A technique, and its applications, for high resolution, rapid, and simple nanopatterning. The general method has been demonstrated in several forms and applications. One is patterning nanophotonic structures at an optical fiber tip for refractive index sensing. Another is patterning nanoresonator structures on a sensor substrate for plasmonic effect related detection of VOCs. In the latter example, a graphene oxide coated plasmonic crystal as a gas sensor capable of identifying different gas species using an array of such structures. By coating the surface of multiple identical plasmonic crystals with different thicknesses of Graphene-Oxide (GO) layer, the effective refractive index of the GO layer on each plasmonic crystal is differently modulated when exposed to a specific gas. Identification of various gas species is accomplished using pattern recognition algorithm.

Abstract: Devices and methods are provided for fatigue testing a medical device, e.g., an annuloplasty ring, using a cam rotatably mounted relative to a base and one or more sets of mounts on the base for securing opposite ends of the medical device. For example, each set of mounts may include a stationary mount on the base, a sliding mount on the base adjacent the cam, and a follower slidably mounted to the sliding mount that contacts the cam such that the follower reciprocates along a horizontal axis as the cam rotates about a vertical axis. The follower and stationary mount include connectors to secure opposite ends, respectively, of a medical device such that rotation of the cam causes the follower to reciprocate and apply tensile and/or compressive loads to fatigue test the medical device.

Abstract: A computing device for use in a system for mapping brain activity of a subject includes a processor. The processor is programmed to select a plurality of measurements of brain activity that is representative of at least one parameter of a brain of the subject during a resting state. Moreover, the processor is programmed to compare at least one data point from each of the measurements with a corresponding data point from a previously acquired data set from at least one other subject. The processor is also programmed to produce at least one map for each of the measurements based on the comparison of the resting state data point and the corresponding previously acquired data point. The processor may also be programmed to categorize the brain activity in a plurality of networks in the brain based on the map.

Abstract: Disclosed is a Brillouin-optical coherence-speckle based multi-mode elasticity measurement device, including a Brillouin-optical coherence elastography common-path scanning unit, a Brillouin scattering elastography system, an optical coherence elastography system, a speckle elastography system, and a time sequence controller, where the Brillouin scattering elastography system and the optical coherence elastography system share the Brillouin-optical coherence elastography common-path scanning unit.

Abstract: A three-dimensional (3D) magnetic particle imaging (MPI) method and system without rotating a field-free line (FFL) are disclosed. In accordance with the method, an FFL is generated such that magnetic particles in a region far from the FFL enter a magnetic saturation state. Further, a non-uniform mixed-frequency excitation magnetic field parallel to the FFL is applied to generate intermodulation response signals. In addition, the intermodulation response signals are acquired, amplified and filtered. Moreover, the intermodulation response signals are transmitted to a digital signal processing unit and an image reconstruction unit, and an encoding matrix is constructed. Additionally, a one-dimensional (1D) concentration distribution of the magnetic particles is reconstructed based on the encoding matrix and an actually measured voltage signal. The FFL is driven for line-by-line scanning along a vertical plane of the FFL, thereby achieving 3D imaging.

Abstract: The invention discloses an atmospheric water harvesting device based on a semiconductor chilling plate and a preparation method thereof. A first anti-gravity wicking material and a second anti-gravity wicking material are used as water transmission channel to realize a continuous atmospheric water harvesting on the same plane, the first anti-gravity wicking material and the second anti-gravity wicking material are combined with the semiconductor chilling plate, and the cold side can continuously maintain the temperature of the hygroscopic area, so that the hygroscopic salt on the surface of the anti-gravity wicking material maintains a stable moisture absorbing rate. The heat at the hot side can accurately heat the desorbing area on the surface of the material, the cooling capacity and the heat of the semiconductor chilling plate can be fully utilized, and the atmospheric water absorbing with low energy consumption is realized.

Abstract: Disclosed is a method for synthesizing an O-antigen saccharide chain of Helicobacter pylori serotype O:6 using seven glycosylation building blocks. Inexpensive and easily available D-glucosamine, D-galactose, D-mannose and L-fucose are used as starting materials, and seven glycosylation building blocks are obtained through a series of chemical reactions. The saccharide building blocks are then selectively linked together to produce O-antigen oligosaccharide chains of Helicobacter pylori serotype O:6 with different saccharide configuration through a series of glycosylation reactions. Also disclosed is a method to assemble an amino linker at the reducing end of the O-antigen saccharide chain of Helicobacter pylori serotype O:6, and the synthesized oligosaccharide chain with an amino linker can be coupled to a carrier molecule or immobilized on a matrix.

Abstract: Described herein are methods for identification/discovery of protein biomarkers for chronic kidney disease (CKD) and diagnosing and/or prognosing and/or predicting progression of and/or treating chronic kidney disease (CKD).

Abstract: Embodiments herein report compositions, methods, uses and manufacturing procedures for rotavirus constructs and immunogenic compositions thereof. Some embodiments concern compositions that include, but are not limited to, chimeric rotaviruses of use in immunogenic compositions against rotavirus infection as well as against other pathogenic virus infection in a subject. In certain embodiments, constructs of use herein can be generated and used where a rotavirus expression system further includes one or more nucleic acid molecules encoding one or more polypeptides of another pathogen (e.g. another enteric or mucosal pathogen).

Abstract: A nanomedicinal composition comprising a nanocarrier and a pharmaceutical agent mixture comprising an anti-cancer therapeutic and an antioxidant. The nanocarrier comprises a porous silicate matrix and particles of a magnetic ferrite disposed in the pores of the porous silicate matrix. The pharmaceutical agent mixture is disposed in the pores and/or on the surface of the nanocarrier by a solution phase impregnation process. The nanomedicinal composition is used in a method of treating breast cancer.

Abstract: A method of producing polycrystalline Y3Ba5Cu8Oy (Y-358) whereby powders of yttrium (III) oxide, a barium (II) salt, and copper (II) oxide are pelletized, calcined at 850 to 950° C. for 8 to 16 hours, ball milled under controlled conditions, pelletized again and sintered in an oxygen atmosphere at 900 to 1000° C. for up to 72 hours. The polycrystalline Y3Ba5Cu8Oy thus produced is in the form of elongated crystals having an average length of 2 to 10 ?m and an average width of 1 to 2 ?m, and embedded with spherical nanoparticles of yttrium deficient Y3Ba5Cu8Oy having an average diameter of 5 to 20 nm. The spherical nanoparticles are present as agglomerates having flower-like morphology with an average particles size of 30 to 60 nm. The ball milled polycrystalline Y3Ba5Cu8Oy prepared under controlled conditions shows significant enhancement of superconducting and flux pinning properties.

Abstract: An apparatus for transmitting power wirelessly using capacitive coupling, provided in a wearable device, includes: a transmission electrode including a plurality of unit electrode pairs, each unit electrode pair being formed by a transmission signal electrode and a transmission ground electrode; and a control module configured to select a unit electrode pair, forming capacitive coupling with the reception electrode, among the plurality of unit electrode pairs provided in the reception electrode, to wirelessly transmit power to a reception electrode included in an implantable device.

Abstract: A zero-watermarking method and device for BIM data, and a medium are provided, which relate to the field of watermarking information security technologies. Aiming at existing zero-watermarking method for the BIM data cannot resist primitive attacks, vertical stability of a model is used to construct a mapping relationship between primitive clusters and watermarking bits, calculate norms of primitives in each primitive cluster of the primitive clusters, take positivity and negativity of norm skewness measurement of the primitives as eigenvalues to construct a binary sequence, and performs an XOR process on the binary sequence and an original watermarking sequence to construct the zero-watermarking for the BIM data. Experimental results indicate that the zero-watermarking method has uniqueness, robustness and security.