Abstract: A mold structure having high-precision multi-dimensional components which includes a first oxide layer superimposed on a top of a first semiconductor substrate; a second oxide layer superimposed on a top of a second semiconductor substrate; integrated designs patterned in at least one of the oxide layers; and the first and second semiconductor substrates bonded to one another into a three dimensional (3D) mold such that the first oxide layer only makes partial contact with the second oxide layer such that a portion of the first oxide layer avoids contact with the second oxide layer, the portion of the first oxide layer directly opposite a surface portion of the second semiconductor substrate that is free of the second oxide, the 3D mold selectively filled with a filling material to form a molded high-precision multi-dimensional component.

Abstract: The invention relates to improved cardiac pacemakers and methods of use thereof. In particular the cardiac pacemakers are useful for normalizing heart rates over resting heart rates in order to condition the heart to improve overall cardiac output.

Abstract: Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve using a cuff to apply pressure to an artery in a subject to determine a plurality of baseline values for a parameter related to endothelial function as a function of applied pressure (Pm); b) applying a stimulus to the subject; and applying external pressure Pm to the artery to determine a plurality of stimulus-effected values for the parameter related to endothelial function as a function of applied pressure (Pm); where the baseline values are determined from measurements made when said mammal is not substantially effected by said stimulus and differences in said baseline values and said stimulus-effected values provide a measure of endothelial function in said mammal.

Abstract: Traps, devices, systems, compositions, and methods for trapping bed bugs, and similar insects with sticky traps having a smooth perimeter surface around the sticky surface, where the smooth perimeter surface can be abraded to a selected texture having both smoothness and roughness qualities. The surfaces are textured so that bed bugs are not able to use the surfaces to pull themselves from the sticky surface, and the textured surface is not so smooth as to cause the bed bugs to avoid the textured surface.

Abstract: An apparatus and a method for monitoring in-band OSNR (Optical Signal-to-Noise Ratio) which monitors the in-band OSNR by using two parallel Mach-Zehnder-interferometers with different optical time delays are disclosed. The apparatus and method can be resistant to chromatic dispersion, polarization mode dispersion and polarized noise, can measure the coherence characteristics of the signal without removing the noise, and can be manufactured into a semiconductor integrated device and be applied in the future high-speed optical network.

Abstract: A system and method for transmitting data over a wireless communication network. The method broadly includes generating a frequency hopping pattern spanning a plurality of time hops and a plurality of signal frequencies; generating a signal including a number of data symbols, the signal incorporating the frequency hopping pattern such that the symbols are distributed across the signal frequencies according to the frequency hopping pattern; transmitting the signal from a transmitting unit to a receiving unit over the wireless communication network; and generating an exact symbol error rate for the signal as received by the receiving unit.

Abstract: Instruction issue circuits are disclosed that are configured to issue multiple instructions within a superscalar pipeline of a microprocessor. The instruction issue circuit includes an instruction queue that stores instructions. A ready generation circuit is operably associated with the instruction queue and generates ready signals that indicate which instructions in the instruction queue are ready for execution. To simplify the instruction issue circuit, the instruction issue circuit has group blocks. Each group block receives a different group of the ready signals corresponding to a different group of the instructions. Each group block generates a group output indicating a group set within the corresponding group of the instructions that has a highest instruction execution priority and are ready for execution. By splitting the ready signals into groups, the groups of ready signals can be processed in parallel thereby reducing both the resulting delay and complexity of the instruction issue circuit.

Abstract: Some embodiments include a method of providing an electronic device. The method includes: (i) providing a carrier substrate, (ii) providing a device substrate comprising a first side and a second side opposite the first side, the device substrate having a flexible substrate, (iii) coupling the first side of the device substrate to the carrier substrate; and (iv) after coupling the first side of the device substrate to the carrier substrate, providing two or more active sections over the second side of the device substrate, each active section of the two or more active sections being spatially separate from each other and having at least one semiconductor device. Other embodiments of related methods and devices are also disclosed.

Abstract: A memory device for multiple processors capable of processing a plurality of memory access requests and a memory system having the same are provided. The memory device includes one command and control signal port configured to receive a command and control signal from a memory controller, one address port configured to receive an address signal from the memory controller, a data port configured to form a plurality of data channels being independently driven to simultaneously process a plurality of memory access requests of the memory controller, and a plurality of memory banks divided into a plurality of sub-banks to simultaneously perform operations according to the plurality of memory access requests when the plurality of memory access requests are sequentially transmitted through the command and control signal port and the address port.

Abstract: A skyrmion driving method that utilizes electric current to make it possible to perform driving ON-OFF control at high speed and to suppress the influence of an inertial effect so that the driving control can be performed further logically. The skyrmion is driven based on a driving amount proportional to a time-integrated value of an electric current density j(t) (Am?2) at a clock time t for a location R(t) of the skyrmion at the clock time t and on a driving amount that is in accordance with a diffusive motion due to thermal fluctuation and increases as a Gilbert attenuation constant increases.

Abstract: A system and method is provided for automated polyp detection in optical colonoscopy images. The system includes an input configured to acquire a series of optical images, and a processor configured to process the optical images. Processing steps include performing a boundary classification with steps comprising locating a series of edge pixels using at least one acquired optical image, selecting an image patch around each said edge pixel, performing a classification threshold analysis on each image patch of said edge pixels using a set of determined boundary classifiers, and identifying, based on the classification threshold analysis, polyp edge pixels consistent with a polyp edge. Processing steps for the processor also include performing a vote accumulation, using the identified polyp edge pixels, to determine a polyp location. The system also includes an output configured to indicate potential polyps using the determined polyp location.

Abstract: The invention concerns an anatomically personalized and mobilizing external support configured to be arranged to support a physical joint between a first and a second bone group, which support comprises at least one first external auxiliary frame, which is configured to be attached to the first bone group using invasive attachment means, at least one second external auxiliary frame, which is configured to be attached to the second bone group using invasive attachment means, and at least one external auxiliary joint, which is fitted between the first and the second auxiliary frame.

Abstract: Spin labeled ice binding compounds (IBCs) including ice binding proteins (IBPs), also called antifreeze proteins (AFPs) and their analogs are exploited to carry the paramagnetic centers for dynamic nuclear polarization (DNP), for enhancing nuclear magnetic resonance (NMR) signal intensities. Use of spin labeled IBCs to perform DNP exploits the IBCs' ability to homogeneously distribute the paramagnetic centers in frozen water solution at low temperature, leading to high DNP efficiency. Other advantages of using spin labeled IBCs include: (1) ability to cryo-protect biological samples; (2) the relative positions and orientations of the spin labeling groups in an IBC may also be cryo-preserved; (3) positions and orientations of spin labeling groups to an IBC can be selected with great freedom and without technical barrier to making multiple spin labels in an IBC; and (4) water solubilities of spin labeled IBCs are potentially high, enabling use of a solvent that is primarily water for DNP at low temperatures.

Abstract: A gas concentration apparatus and a method of operating the gas concentration apparatus are provided. The gas concentration apparatus includes a gas concentration module. The gas concentration module includes a base component having a chamber configured to accommodate carbon foam, a gas inlet connected to one side of the chamber, a gas outlet connected to the other side of the chamber, and a heating device disposed on at least one side of the substrate.

Abstract: The invention provides for methods for treating a hair loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of Transcription inhibitor.

Abstract: Disclosed is a method for analyzing retinal image data obtained using spectral-domain optical coherence tomography (SD-OCT). The image data comprise a cross-section of the retina and an en face image of the retina of a subject having AMD (age-related macular degeneration). The image data are processed to obtain an accurate structure showing locations, shape, size, and other data on drusen (deposits under the retina). This structural information is processed to extract quantitative drusen features that are indicative of a risk of progression of AMD from the dry form to the wet form of the disease in a given subject and defined time period, including short time intervals (one year or less). Relevant drusen features used include number, en face area and volume of drusen detected; shape of drusen detected; density of drusen; and reflectivity of drusen.

Abstract: Provided are beverage compositions comprising a urine citrate increasing component and a urine oxalate reducing component. The beverage compositions may be provided in a ready-to-drink form or may be provided in a concentrate form. Also provided are kits comprising the beverage compositions and methods for treating various conditions using the beverage compositions.

Abstract: A compound that can function as a Cyclophilin D can include a structure of Formula 1 or Formula 2 or Formula 3 or Formula 4 or Formula 5 or Formula 6 or Formula 7 or Formula 8, derivative thereof, prodrug thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combination thereof, as presented herein. The Cyclophilin D inhibitors can inhibit onset or treat neurodegenerative disease, such as Alzheimer's disease, or can be used for inhibiting progression or treating diabetes.

Abstract: The present invention provides dendrimer conjugates. The present invention provides a composition comprising a dendrimer conjugate and a cell, such as a cell covered with dendrimer conjugates, in which dendrimer conjugates home the cell to a target tissue.

Abstract: ‘NCCX2’ is a new cultivar of hybrid beautyberry with a compact habit, purple emerging and fall foliage and abundant pink-purple fruit in the fall.