Abstract: A process for producing a metal oxide powder comprising: providing a precursor solution or dispersion containing a metal complex; spraying the precursor solution on to a heated substrate in the presence of water, thereby depositing material on the substrate; drying the deposited material; and removing the deposited material from the substrate to produce the metal oxide powder.
Type:
Grant
Filed:
February 6, 2017
Date of Patent:
January 12, 2021
Assignee:
OXFORD UNIVERSITY INNOVATION LIMITED
Inventors:
Peter Edwards, Jonathan Dilworth, Vladimir Kuznetsov, Catherine Hayes
Abstract: The invention provides a compound of formula (I): or a salt thereof, wherein R1 and R2 have any of the values defined in the specification, as well as methods of using such compounds and salts to separate an aryl compound from a mixture.
Type:
Grant
Filed:
February 11, 2020
Date of Patent:
January 12, 2021
Assignee:
University of Iowa Research Foundation
Inventors:
Leonard MacGillivray, Gonzalo Campillo-Alvarado
Abstract: A computer-implemented method, a computer system and a non-transitory computer-readable medium for constructing human-readable sentences from imaging data of a subject can include: receiving imaging data including image elements of at least one region of interest of the subject; segmenting the imaging data of the region of interest into a plurality of sub-regions, where each sub-region includes a portion of the image elements; calculating an abnormality factor for each of the sub-regions by quantitatively analyzing segmented image information of the imaging data of the sub-regions using data from a normal database; comparing each abnormality factor to a threshold value; constructing a human-understandable sentence for the subject when a corresponding abnormality factor exceeds the threshold, where each human-understandable sentence references a physical structure threshold associated with the calculation for the region or sub-region; and outputting the human-understandable sentences for the at least one regio
Abstract: Methods and devices for detecting metabolic activity of target cells in a sample. The target cells are concentrated in a nanoliter well having a microfilter. A reporter compound that exhibits a change in electrochemical state in response to metabolic activity of the target cells is introduced. Metabolic activity or viability of the target cells is detected based on a determined change in the electrochemical state of contents in the well.
Type:
Grant
Filed:
September 13, 2019
Date of Patent:
January 12, 2021
Assignee:
The Governing Council of the University of Toronto
Inventors:
Shana Olwyn Kelley, Edward Hartley Sargent, Justin David Besant
Abstract: The described embodiments are directed to a system and methods of calibrating a fluorescence microscope and/or light detection device using a calibrating apparatus. The apparatus may comprise a main body housing, a sensor head, and a microcontroller assembly disposed within the housing. The housing may include an adapter to mechanically couple the housing to a microscope. The sensor head may comprise (i) an optical power sensor to produce a power signal representative of an optical power magnitude of light applied to the optical power sensor, (ii) an optical wavelength sensor configured to produce wavelength information associated with the light applied to the optical wavelength sensor, and (iii) a light source configured to direct light toward a detection device associated with the microscope. The microcontroller assembly may be configured to generate an optical power magnitude value based on the power signal and adjusted according to the wavelength information.
Type:
Grant
Filed:
December 4, 2019
Date of Patent:
January 12, 2021
Assignee:
University of Massachusetts
Inventors:
David Grunwald, Maximiliaan Huisman, Carlas Smith
Abstract: An automatic protocol test method by reverse engineering from packet traces to extended finite state machine is disclosed. The method includes following steps: parsing the plurality of packets to extract a plurality of sessions; conducting a keyword analysis and a clustering algorithm to obtain protocol messages; initializing the protocol messages and merging equivalent states to obtain a finite state machine; extracting fields and values of the protocol messages to obtain a plurality of sub-datasets and adding a data guard and set of memories on the finite state machine to obtain the extended finite state machine.
Type:
Grant
Filed:
May 2, 2019
Date of Patent:
January 12, 2021
Assignee:
NATIONAL CHIAO TUNG UNIVERSITY
Inventors:
Ying-Dar Lin, Quan-Bui Tien, Yu-Kuen Lai, Yuan-Cheng Lai
Abstract: For example, the present techniques may provide an energy-efficient multipurpose encryption engine capable of processing both AES and CRC algorithms using a shared Galois Field Computation Unit (GFCU). In an embodiment, an apparatus may comprise computation circuitry adapted to perform Galois Field computations and control circuitry adapted to control the computation circuitry so as to selectively compute either an Advanced Encryption Standard cipher or a Cyclic Redundancy Check.
Type:
Grant
Filed:
December 10, 2018
Date of Patent:
January 12, 2021
Assignee:
The Board of Regents of The University of Texas System
Inventors:
Safwat Mostafa Noor, Eugene Britto John
Abstract: There is disclosed herein methods, uses and systems for the detection, diagnosis, prognosis, treatment or prevention of a disease or condition comprising cartilage degeneration in a subject that is in need thereof. The methods comprise the use, inhibition or measurement of at least one of miR-181 a-5p and miR-4454, in the subject.
Type:
Grant
Filed:
January 31, 2017
Date of Patent:
January 12, 2021
Assignee:
UNIVERSITY HEALTH NETWORK
Inventors:
Mohit Kapoor, Akihiro Nakamura, Raja Rampersaud
Abstract: The present invention provides a polyploid adeno-associated virus (AAV) capsid, wherein the capsid comprises capsid protein VP1, wherein said capsid protein VP1 is from one or more than one first AAV serotype, wherein said capsid protein VP2 is from one or more than one first AAV serotype and capsid protein VP3, wherein said capsid protein VP3 is from one or more than one second AAV serotype and wherein at least one of said first AAV serotype is different from at least one of said second AAV serotype and is different from at least one of said third AAV serotype, in any combination.
Type:
Grant
Filed:
October 10, 2019
Date of Patent:
January 12, 2021
Assignee:
The University of North Carolina at Chapel Hill
Abstract: The present invention relates to methods and kits for detecting a fusion mRNA transcript or polypeptide encoded by the fusion mRNA transcript. The method includes obtaining a biological sample from a subject and providing one or more reagents capable of binding a fusion mRNA transcript or polypeptide encoded by the fusion mRNA transcript, wherein the fusion mRNA transcript or polypeptide encoded by the fusion mRNA transcript comprises the 3? end of ex on 25 of INPP5D fused to the 5? end of ex on 2 of ATG16L1 or the polypeptide encoded by the 3? end of ex on 25 of INPP5D fused to the 5? end of ex on 2 of ATG16L1, respectively.
Type:
Grant
Filed:
October 6, 2017
Date of Patent:
January 12, 2021
Assignee:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Inventors:
Frank Middleton, William G. Kerr, Sandra Fernandes Denney
Abstract: A pattern stimulus system is described that includes a hemispherical concave surface, a plurality of illumination sources, and a controller. The illumination sources are arranged on the hemispherical concave surface in a plurality of annular rows and a plurality of radial columns. The control is configured to operate the illumination sources to display a checkerboard pattern by illuminating a first subset of the illumination sources and dimming a second subset of the illumination sources. The control is further configured to invert the checkerboard pattern by dimming the first subset of the illumination sources and illuminating the second subset of the illumination sources. Methods are also described for using the pattern stimulus system to evaluate a condition of the eye and to diagnose diseases of the eye.
Type:
Grant
Filed:
May 21, 2019
Date of Patent:
January 12, 2021
Assignee:
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
Inventors:
John Hetling, Zahra Derafshi, Shresta Patangay
Abstract: A radiofrequency ablation electrode needle includes at least one first segment and at least two second segments. The at least one first segment and the at least two second segments are exposed on a surface of the needle body. An impedance of the at least one first segment is smaller than an impedance of the at least two second segments and at least one of the at least one first segment is disposed between two immediately adjacent ones of the at least two second segments. Besides, the radiofrequency ablation electrode needle is a monopolar electrode needle.
Type:
Grant
Filed:
December 14, 2016
Date of Patent:
January 12, 2021
Assignees:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE, NATIONAL TAIWAN UNIVERSITY HOSPITAL
Abstract: The present invention relates to a device for evaluating the performance of a superconductive coil for a high-temperature superconductive rotary machine and a method for evaluating the performance of a superconductive coil thereby. The technical gist of the present invention is to provide schemes for evaluating the stability of a superconductive coil and verifying the reliability thereof, to evaluate/confirm whether or not the same can be commercialized, and to evaluate/confirm the threshold current of a superconductive wire for manufacturing a superconductive coil or the upper limit of the operating current thereof, and is characterized in that the electromagnetic, thermal, and mechanical performances of a superconductive coil for a second-generation high-temperature superconductive rotary machine can be evaluated.
Type:
Grant
Filed:
April 23, 2018
Date of Patent:
January 12, 2021
Assignee:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION JEJU NATIONAL UNIVERSITY
Abstract: Provided are a system and method for processing a beam position monitor signal using an analog-to-digital converter (ADC) sampler corresponding to an analog part and an FPGA corresponding to a digital signal processing part. The ADC sampler measures signal intensity through an optimization of an ADC sampling rate and bits using a radio frequency (RF) switch and a low noise amplifier (LNA), and converts an analog signal into a digital signal. The FPGA extracts only an optimized harmonic signal among multiple harmonic signals of the digital signal converted by the ADC sampler, through a digital band pass filter; and performs beam position measurement, beam phase measurement and relative beam current measurement on the extracted digital signal through a digital circuit.
Type:
Grant
Filed:
September 28, 2018
Date of Patent:
January 12, 2021
Assignee:
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS
Abstract: There is provided a translation-rotation hybrid vibration control system for buildings, which includes a translation control unit and a rotation control unit. The translation control unit is provided on an external building structure. The rotation control unit is provided above the translation control unit. The translation control unit includes a fixed base, a first track plate, a first movable plate, a second track plate and a second movable plate. The rotation control unit includes a force-transfer base, a drive, a reducer, an output shaft, a rotary plate and a flange.
Abstract: Disclosed are an electronic impedance tuning apparatus for measuring a load-pull of a mobile amplifier and an electronic impedance tuning method therefor. An electronic impedance tuning apparatus according to one embodiment of the present invention comprises: a coupler for transferring, to transmission lines respectively connected to a through port and a coupled port, an input voltage inputted to an input port; a magnitude part for controlling a change in the magnitude of the impedance through a change in length difference of the transmission lines; and a phase part for controlling a change in the phase of the impedance through an equal length change of the transmission lines.
Type:
Grant
Filed:
November 8, 2016
Date of Patent:
January 12, 2021
Assignee:
INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
Abstract: An orthogonally polarized Yagi-like MIMO antenna system and a triangular printed wideband Yagi based MIMO antenna system, respectively, and methods for making the antennas. The orthogonally polarized Yagi-like MIMO antenna system includes two slot round loop elements on a top side of a substrate. Each slot round loop element has two input ports and two slot reflectors. For each slot round loop element, one of the two input ports is placed orthogonally to the other input port, and one of the two slot reflectors is placed orthogonally to the other slot reflector. The triangular printed wideband Yagi based MIMO antenna system includes three round loop elements on a top side of a substrate and a circular reflector on a bottom side of the substrate. Each of the three round loop elements is placed at 120° with respect to other two round loop elements and has three parasitic directors.
Type:
Grant
Filed:
July 12, 2019
Date of Patent:
January 12, 2021
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Mohammad S. Sharawi, Syed Shahan Jehangir
Abstract: Automated and objective methods for quantifying a retinal characteristic include segmenting an optical coherence tomography image into a plurality of layered retinal regions, and quantifying the retinal characteristic for each region as normalized to a range defined by the characteristic value in the vitreous region and in the retinal pigment epithelium region. Such methods are useful for detecting occult ocular pathology, diagnosing ocular pathology, reducing age-bias in OCT image analysis, and monitoring efficacy ocular/retinal disease therapies.
Type:
Grant
Filed:
March 1, 2016
Date of Patent:
January 12, 2021
Assignee:
University of Louisville Research Foundation, Inc.
Inventors:
Shlomit Schaal, Ayman El-Baz, Amir Reza Harjrasouliha
Abstract: A method for preparing a biflavone-iron complex, includes using the amentoflavone as the ligand and the ferric ion as the central ion, the amentoflavone-iron complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-iron complex are studied in the present invention. MTT method shows that the amentoflavone-iron complex has a relatively good antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-iron complex is stronger than that of the amentoflavone itself.
Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.
Type:
Grant
Filed:
August 21, 2018
Date of Patent:
January 12, 2021
Assignees:
Singapore Health Services PTE LTD, National University of Singapore
Inventors:
Stuart Alexander Cook, Sebastian Schaefer