Abstract: A photodiode comprising a photoactive spinel oxide layer is described. This photoactive spinel oxide layer forms a contact with both a light absorption layer of quantum dots, quantum wires, or quantum rods, and an inorganic substrate layer. In some embodiments, the inorganic substrate layer and the photoactive spinel oxide layer form an isotype junction. Methods of characterizing the photodiode are provided and demonstrate commercially relevant electrical and optoelectronic properties, particularly the ability to operate as a photodetector with a high photosensitivity. An economical process for preparing the photodiode is provided as well as applications.
Type:
Grant
Filed:
July 31, 2020
Date of Patent:
January 12, 2021
Assignee:
King Abdulaziz University
Inventors:
Wageh Swelm, Fahrettin Yakuphanoglu, Ahmed A. Al-Ghamdi, Yusuf Abdulaziz Al-Turki
Abstract: Disclosed are a fluorescent dye, a preparation method and an application thereof. The fluorescent dye has a structure of formula (I), where X and Y are independently selected from O, S, C(CH3)2 and NR6; R2 and R3 are independently hydrogen or a functional group; R1, R4, R5 and R6 are independently selected from functional groups; and Z? is a negative ion. The fluorescent dye has an ability to permeate the living cell membrane, so that it can be used in the fluorescence imaging of living cell microstructures, and can also be used in the STED super-resolution fluorescence imaging and laser scanning confocal microscopy of live cells.
Abstract: The present invention provides methods and kits for performing microbial sensitivity tests. Specifically, the invention relates to methods for identifying the susceptibility, tolerance or resistance of a microorganism to one or more antimicrobial agents, and the level of tolerance. The method comprises exposing the microorganism grown on a plate surface to one or more antimicrobial agents and to at least one growth promoting agent.
Type:
Grant
Filed:
October 18, 2016
Date of Patent:
January 12, 2021
Assignee:
Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Abstract: A plugging agent with temperature-resistant, salt-resistant and high-expansion for plugging large fractures and a preparation method thereof of the present disclosure are provided, the plugging agent system consists of the following components: main agent: 6%˜10%, cross-linking agent: 0.6%˜1%, initiator: 0.006%˜0.01%, additive: 6%˜14%, and the rest being water; the preparation method includes the following steps: adding montmorillonite to water to prepare a montmorillonite dispersion system; adding the main agent, the cross-linking agent and the initiator to the montmorillonite dispersion system to prepare a main agent solution; putting the main agent solution into an oven with a temperature range with 90˜20° C. for 9˜48 h to obtain gelation, the adhesive strength of the agent system can reach grade H, with 50˜80 expansion multiple, good strength after being expanded and good water plugging effect under the condition of a temperature of 140° C. and 250,000 degree of mineralization.
Type:
Grant
Filed:
September 15, 2020
Date of Patent:
January 12, 2021
Assignee:
SOUTHWEST PETROLEUM UNIVERSITY
Inventors:
Fa Yang Jin, Wan Fen Pu, Wen Ge Hu, Hai Yang Zhao, Long He, Dai Jun Du, Ke Xing Li, Bao Lei Jiao, Bo Ren, Lin Sun, Zhen Qian, En Long Zhen, Rui Liu, Xiao Qing He
Abstract: Exemplary quantitative susceptibility mapping methods, systems and computer-accessible medium can be provided to generate images of tissue magnetism property from complex magnetic resonance imaging data using the Bayesian inference approach, which minimizes a cost function consisting of a data fidelity term and two regularization terms. The data fidelity term is constructed directly from the complex magnetic resonance imaging data. The first prior is constructed from matching structures or information content in known morphology. The second prior is constructed from a region having an approximately homogenous and known susceptibility value and a characteristic feature on anatomic images. The quantitative susceptibility map can be determined by minimizing the cost function. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining magnetic susceptibility information associated with at least one structure.
Type:
Grant
Filed:
April 3, 2018
Date of Patent:
January 12, 2021
Assignee:
Cornell University
Inventors:
Yi Wang, Zhe Liu, Youngwook Kee, Alexey Dimov, Yan Wen, Jingwei Zhang, Pascal Spincemaille
Abstract: The present invention relates to a cell comprising a gene encoding a polypeptide of interest, wherein the polypeptide of interest is expressed comprising one or more posttranslational modification patterns. These modifications are useful for example in improvement of pharmacokinetic properties, i.e. by attaching PEG chains to proteins. The present invention also relates to methods for producing the antibodies and compositions comprising the antibodies, and their uses.
Type:
Grant
Filed:
June 15, 2016
Date of Patent:
January 12, 2021
Assignees:
UNIVERSITY OF COPENHAGEN, DANMARKS TEKNISKE UNIVERSITET
Inventors:
Shamim Herbert Rahman, Carsten Behrens, Malene Bech Vester-Christensen, Henrik Clausen, Zhang Yang, Adnan Fevzi Halim, Eric Bennett
Abstract: A drilling fluid composition including a viscosifier, treated date pit particles which are i) de-oiled and ii) treated with a base or both a base and an acid, and an aqueous base fluid, wherein the treated date pit particles are present in an amount of 0.01-5 wt %, relative to a total weight of the drilling fluid composition. A method of making the drilling fluid composition by de-oiling date pit particles, treating with a base or a base and an acid in a freeze/thaw process, and adding the freeze/thaw mixture to the viscosifier and the aqueous base fluid. A process for drilling a subterranean geological formation with the drilling fluid composition.
Type:
Grant
Filed:
September 9, 2019
Date of Patent:
January 12, 2021
Assignee:
KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
Abstract: Methods for treating and preventing neurodegenerative disease, neurological injury, including stroke, via administration of Transient receptor potential M2 (TRPM2)-inhibitors. The inhibitors may be administered in conjunction with another therapeutic agent or therapeutic regimen. The peptides may be administered to a human male. The peptides may be administered within eight hours of a neurological injury, such as a stroke.
Type:
Grant
Filed:
February 23, 2017
Date of Patent:
January 12, 2021
Assignee:
The Regents of the University of Colorado, a body corporate
Abstract: Disclosed is a quantum dot light emitting device including a ligand-substituted quantum dot light emitting layer with a polymer having amine groups. The introduction of the ligand-substituted quantum dot light emitting layer with a polymer having amine groups changes the energy level of an electron transport layer and enables control over the charge injection properties of the device so that the flow of electrons can be controlled. In addition, the ligand substitution is effective in removing oleic acid as a stabilizer of quantum dots to prevent an increase in driving voltage caused by the introduction of the additional material, achieving markedly improved efficiency of the device. Also disclosed is a method for fabricating the quantum dot light emitting device.
Type:
Grant
Filed:
June 2, 2017
Date of Patent:
January 12, 2021
Assignees:
Korea University Research and Business Foundation, Korea Institute of Science and Technology
Abstract: The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided.
Type:
Grant
Filed:
December 7, 2017
Date of Patent:
January 12, 2021
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
Chia-Yung Wu, James Onuffer, Wendell A. Lim
Abstract: The present invention relates to a switching device, a method of fabricating the same, and a nonvolatile memory device including the same. A switching device according to an embodiment of the present invention includes a first electrode; a second electrode; and a switching film which is disposed between the first electrode and the second electrode, and includes an electrically insulating matrix and a conductive path formed in the electrically insulating matrix. In this embodiment, the conductive path includes crystalline metal clusters dispersed in the electrically insulating matrix and a metal bridge connecting adjacent crystalline metal clusters.
Type:
Grant
Filed:
January 18, 2019
Date of Patent:
January 12, 2021
Assignees:
SK hynix Inc., Seoul National University R&DB Foundation
Inventors:
Hyeong Joon Kim, Ji Woon Park, Young Seok Kim
Abstract: Methods and systems for detecting early stage dental caries and decays are provided. In particular, in an embodiment, laser-induced autofluorescence (AF) from multiple excitation wavelengths is obtained and analyzed. Endogenous fluorophores residing in the enamel naturally fluoresce when illuminated by wavelengths ranging from ultraviolet into the visible spectrum. The relative intensities of the AF emission changes between different excitation wavelengths when the enamel changes from healthy to demineralized. By taking a ratio of AF emission spectra integrals between different excitation wavelengths, a standard is created wherein changes in AF ratios within a tooth are quantified and serve as indicators of early stage enamel demineralization. The techniques described herein may be used in conjunction with a scanning fiber endoscope (SFE) to provide a reliable, safe and low-cost means for identifying dental caries or decays.
Type:
Grant
Filed:
January 11, 2018
Date of Patent:
January 12, 2021
Assignee:
University of Washington through its Center for Commercialization
Abstract: A method for preparing a boron-containing low-carbon steel oxide film includes performing micro-arc oxidation on boron-containing low-carbon steel in an electrolyte by using the boron-containing low-carbon steel as an anode, to obtain a boron-containing low-carbon steel oxide film. The electrolyte contains sodium meta aluminate of 5 g/L to 25 g/L, sodium dihydrogen phosphate of 2 g/L to 10 g/L, sodium carbonate of 2 g/L to 15 g/L, and glycerol of 2 g/L to 8 g/L. The preparation method provided by the present invention has a simple and controllable process, and the obtained boron-containing low-carbon steel oxide film has a secure bond with the substrate, thus effectively avoiding occurrence of galvanic corrosion.
Type:
Grant
Filed:
March 28, 2019
Date of Patent:
January 12, 2021
Assignee:
Tianjin University of Technology
Inventors:
Minfang Chen, Yankun Li, Chen You, Haifeng Liu
Abstract: GaN-based nanowire heterostructures have been intensively studied for applications in light emitting diodes (LEDs), lasers, solar cells and solar fuel devices. Surface charge properties play a dominant role on the device performance and have been addressed within the prior art by use of a relatively thick large bandgap AlGaN shell covering the surfaces of axial InGaN nanowire LED heterostructures has been explored and shown substantial promise in reducing surface recombination leading to improved carrier injection efficiency and output power. However, these lead to increased complexity in device design, growth and fabrication processes thereby reducing yield/performance and increasing costs for devices. Accordingly, there are taught self-organising InGaN/AlGaN core-shell quaternary nanowire heterostructures wherein the In-rich core and Al-rich shell spontaneously form during the growth process.
Type:
Grant
Filed:
November 26, 2019
Date of Patent:
January 12, 2021
Assignee:
The Royal Institution for the Advancement of Learning/McGill University
Abstract: Various embodiments of the invention describe an environmentally stable, and exceptionally dense hydrogen storage (6.5 wt % and 0.105 kg H2/L in the total composite, 7.56 wt % in Mg) using atomically thin and gas-selective reduced graphene oxide sheets as encapsulants. Other approaches to protecting reactive materials involve energy intensive introduction of considerable amounts of inactive, protective matrix which compromises energy density. However, these multilaminates are able to deliver exceptionally dense hydrogen storage far-exceeding 2020 DOE target metrics for gravimetric capacity (5.5 wt %), and ultimate full-fleet volumetric targets (0.070 kg H2/L) for fuel cell electric vehicles. Methods of stabilizing reactive nanocrystalline metals in zero-valency also has wide-ranging applications for batteries, catalysis, encapsulants, and energetic materials.
Type:
Grant
Filed:
February 9, 2018
Date of Patent:
January 12, 2021
Assignee:
The Regents of the University of California
Inventors:
Jeffrey J. Urban, Eun Seon Cho, Anne M. Ruminski, Shaul Aloni
Abstract: A motion compensation system includes a plurality of RF transmitters, a plurality of direction of arrival sensors, and a positioning table which together are usable to compensate for intrafraction motion of a patient during a medical procedure. The positioning table may be a secondary table arranged next to or above a primary table such as a radiotherapy couch, allowing for repositioning of part of patient such as the head and neck relative to a remainder of the body. The motion compensation system employs a direction of arrival sensor that includes rotating antenna elements in a configuration that improves the ease and accuracy of signal processing and analysis to identify the position of an RF transmitter affixed to a patient. The repositioning table has six degrees of freedom and is safe for use in imaging and radiation intensive environments.
Type:
Grant
Filed:
January 12, 2017
Date of Patent:
January 12, 2021
Assignee:
VIRGINIA COMMONWEALTH UNIVERSITY
Inventors:
Mark Ostyn, Siyong Kim, Woon-Hong Yeo, Thomas Dwyer, Melvin Rosario, Ross Cruikshank, Daniel Martinez, Charles Cartin
Abstract: Methods, systems and programs for denoising a signal using discrete wavelet transformation are provided. For example, a method for denoising a signal may include determining a number of resolution levels to denoise, determining variable threshold(s) for each resolution level, applying the determined variable threshold(s) to denoise at least a detail component of each of the determined resolution levels. Each variable threshold includes a separately determined lower threshold and upper threshold. The method for denoising a signal may further include transforming, using an inverse discrete wavelet transformation, at least the denoised detail component for each of the determined resolution levels into a denoised signal.
Type:
Grant
Filed:
May 11, 2017
Date of Patent:
January 12, 2021
Assignee:
CORNELL UNIVERSITY
Inventors:
Madhur Srivastava, Jack H. Freed, C. Lindsay Anderson
Abstract: A method of forming an image of a region of interest using a pulse-echo imaging device is described. The method includes the steps of transmitting a pulse, discriminating an echo of the pulse by comparison to a plurality of Hermite polynomials, and determining a color for display based on the comparison. A system for forming an image of a region of interest is also described. The system includes a pulse-echo imaging device for transmitting a pulse and a control unit in communication with the pulse-echo imaging device. The control unit is configured to discriminate an echo of the pulse by comparison to a plurality of Hermite polynomials and determine a color for display based on the comparison.
Abstract: The present invention relates to a method, a device, and a non-transitory computer-readable medium for controlling a tactile interface device. The method of controlling the tactile interface device according to an embodiment of the present invention includes an input information generating step of generating input information into an application being executed in the computing device based on an input from the tactile interface device; and an output information generating step of generating output information to the tactile interface device based on an output of a focus area among an output from the application being executed in the computing device.
Abstract: The present invention relates to biomaterials coated with an active agent eluting coating, wherein implantation of the coated biomaterial results in reduced implant-related complications and/or improved integration of the biomaterial into the host tissue and further relates to kits containing the coated biomaterial. The present invention also relates to methods and kits for coating the biomaterial. It is based, at least in part, on the discovery that biomaterial coated with a cytokine eluting coating resulted in the shift of early stage macrophage polarization that were associated with positive long-term effects such as minimized capsule formation and improved tissue quality and composition as compared to uncoated biomaterials.
Type:
Grant
Filed:
January 13, 2020
Date of Patent:
January 12, 2021
Assignee:
UNIVERSITY OF PITTSBURGH—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
Inventors:
Bryan Nicklaus Brown, Daniel Jordi Hachim Diaz