Abstract: A flow cytometer including a flow cell in which an imaging object flows; a laser beam irradiator configured to radiate laser beam; a camera including an image sensor of N×M pixels; and an optical system configured to introduce the laser beam from the laser beam irradiator to imaging range of flow cell and to introduce signal light, such as transmitted, reflected or scattered light, from imaging range of flow cell, to camera. Optical system includes a mirror device that is placed on a Fourier plane of imaging optical system, that has at least one mirror specularly reflecting the signal light, and that is driven and rotated in conjunction with a flow in flow cell, such that each part of an image formed by the signal light is introduced into an identical pixel of the image sensor for at least a predetermined time period from a predetermined timing.
Abstract: The present invention discloses a cubature Kalman filtering method suitable for high-dimensional GNSS/INS deep coupling, including: S1, constructing a high-dimensional GNSS/INS deep coupling filter model; S2, generating an initialization cubature point for the constructed filter model by using standard cubature rules; S3, performing CKF filtering by using novel cubature point update rules. The present invention is suitable for high-dimensional GNSS/INS deep coupling filtering with high precision and high stability.
Abstract: The present disclosure discloses a control system for enhancing a frequency support capability of a wind turbine generator system. The control system includes a wind turbine, a gearbox, an electric generator and a converter. The control system is characterized by further including a supercapacitor energy storage apparatus, which includes a DC-DC converter and a supercapacitor. The converter includes DC buses, and the supercapacitor is electrically connected to the DC buses via the DC-DC converter. The supercapacitor may be orderly charged or discharged according to an operating state of the wind turbine generator system to maintain its operating condition, and has a superior reliability.
Type:
Grant
Filed:
February 8, 2017
Date of Patent:
January 12, 2021
Assignees:
Wind Power Technology Center of Gansu Electric Power Company, State Grid Corporation of China, Gansu Electric Power Company of State Grid, Shanghai Jiao Tong University
Inventors:
Ningbo Wang, Liang Lu, Kun Ding, Shiyuan Zhou, Chen Zhang, Jin Li, Zheng Li, Nianzong Bai, Jing Zhi, Xu Cai, Zifen Han, Youming Cai
Abstract: A scar subcision devices comprising a first elongated element comprising a pivotal connection to a second elongated element, the first elongated element having a blunt distal end, the second elongated element having a proximal-facing cutting edge at a distal end thereof, the device having a first state wherein the cutting edge is retracted to a location within an outer perimeter of the first elongated element, and a second state wherein the cutting edge is exposed outside of the outer perimeter of the first elongated element and the device transitioning between the first state and the second state by the first elongated element and the second elongated element rotating relative to each other about the pivotal connection are disclosed. Methods are also disclosed.
Type:
Grant
Filed:
February 6, 2020
Date of Patent:
January 12, 2021
Assignee:
Indiana University Research and Technology Corporation
Inventors:
Luke G. Gutwein, Rajiv Sood, Barry Davignon
Abstract: The present invention relates to novel small molecule modulators of Nav1.6 channels of the general formulae (I), (II), (III) and (IV), and the uses thereof.
Type:
Grant
Filed:
November 20, 2017
Date of Patent:
January 12, 2021
Assignee:
The Board of Regents of The University of Texas System
Inventors:
Fernanda Laezza, Jia Zhou, Zhiqing Liu, Syed Ali
Abstract: A system and method for rip-up and re-routing a global routing solution includes determining, via processing circuitry, one or more rip-up and re-route (R&R) strategies for a net; decomposing, via the processing circuitry, multiple pins of the net into a plurality of subnets; decomposing a spanning tree of the net into paths for the plurality of subnets; determining, via the processing circuitry, a probability of success of each of the R&R strategies for one of minimizing a total overflow of a global routing solution or minimizing a wire length of the global routing solution; and applying one of the R&R strategies to the net based on the determined probability of success of said each of the R&R strategies towards improving the global routing solution, wherein the global routing solution includes a plurality of spanning trees for a respective plurality of nets of a global routing system.
Type:
Grant
Filed:
July 26, 2019
Date of Patent:
January 12, 2021
Assignee:
King Fahd University of Petroleum and Minerals
Abstract: Systems and methods for arbitrary viewpoint robotic manipulation and robotic surgical assistance are disclosed. According to an aspect, a system includes one or more controllers configured to receive an image dataset of an actual environment within which the robotic tool is positioned. The controller(s) are also configured to generate a virtual environment of the actual environment based on the image dataset. Further, the controller(s) can control display of the virtual environment including a virtual tool controllable by a user for use to control the robotic tool within the actual environment. The controller(s) can receive user input for altering a perspective view of display of the virtual environment from a first perspective view to a second perspective view. Further, the controller(s) can maintain orientation of display of the virtual tool with respect to the user during display of the first perspective view and the second perspective view of the virtual environment.
Type:
Grant
Filed:
September 12, 2016
Date of Patent:
January 12, 2021
Assignee:
Duke University
Inventors:
Mark Draelos, Kris Hauser, Anthony Kuo, Brenton Keller, Joseph Izatt
Abstract: Pateamine A derivatives, pharmaceutical compositions that include the derivatives, and methods for treating chronic lymphocytic leukemia using the derivatives.
Type:
Grant
Filed:
March 31, 2017
Date of Patent:
January 12, 2021
Assignee:
The Texas A&M University System
Inventors:
Daniel Romo, Kenneth G. Hull, Mingzhao Zhu, Omar Robles
Abstract: The present invention provides a method of treating cancer with a combination of IL-2 (e.g., extended-PK IL-2), an integrin-binding-Fc fusion protein, and a cancer vaccine. The methods of the invention can be used to treat a broad range of cancer types.
Type:
Grant
Filed:
February 10, 2017
Date of Patent:
January 12, 2021
Assignees:
The Board of Trustees of the Leland Stanford Junior University, Massachusetts Institute of Technology
Inventors:
Karl Dane Wittrup, Darrell J. Irvine, Cary Francis Opel, Kelly Dare Moynihan, Jennifer R. Cochran, Byron Hua Kwan
Abstract: Embodiments of a magnetic field sensor of the present disclosure includes magnetoelectric nanowires suspended above a substrate across electrodes without substrate clamping. This results in enhanced magnetoelectric coupling by reducing substrate clamping when compared to layered thin-film architectures. Accordingly, the magnetoelectric nanowires of the magnetic field sensor generate a voltage response in the presence of a magnetic field.
Type:
Grant
Filed:
November 13, 2018
Date of Patent:
January 12, 2021
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
Jennifer S. Andrew, David P. Arnold, Matthew Bauer, Xiao Wen
Abstract: The present invention provides isolated nucleic acid molecules comprising short non-coding protein regulatory RNAs (sprRNA), variants, fragments and inhibitors thereof and compositions and methods of using the same.
Abstract: Interaction with a protein is detected by using an RNA probe containing the following sequences; (i) a complementary strand sequence to a DNA barcode sequence, (ii) a sequence of a first stem portion, (iii) a sequence of a second stem portion complementary to the first stem portion for hybridizing with the first stem portion to form a double-stranded stem, and (iv) a sequence of a loop portion contained in RNA for linking the first and second stem portions.
Abstract: A multi-level caching method and a multi-level caching system for enhancing a graph processing performance are provided. The multi-level caching method includes searching for graph data associated with a query from a first cache memory in which data output in response to a previous query request is stored, when a query request for the query is received, re-searching for the graph data from a second cache memory in which neighboring data with a history of an access to each of data stored in the first cache memory is stored, when the graph data is not found in the first cache memory, and outputting first neighboring data found by the re-searching as the graph data when a response to the query request is output.
Type:
Grant
Filed:
December 14, 2018
Date of Patent:
January 12, 2021
Assignee:
CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Abstract: An anode for oxygen evolution that operates at a small overpotential and in a stable manner, and can be used favorably in an organic chemical hydride electrolytic synthesis apparatus. An anode 10 for oxygen evolution that evolves oxygen in a sulfuric acid aqueous solution containing a substance to be hydrogenated dissolved at a concentration higher than 1 mg/L, wherein an anode substrate 10a is composed of a valve metal, and an anode catalyst layer 10b containing at least one oxide, nitride or carbide of iridium, and at least one oxide, nitride or carbide of at least one metal selected from the group consisting of elements belonging to groups 4, 5 and 13 of the periodic table is formed on the surface of the anode substrate 10a.
Type:
Grant
Filed:
November 9, 2015
Date of Patent:
January 12, 2021
Assignees:
NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY, DE NORA PERMELEC LTD.
Abstract: There is provided a system, method, and a computer program product that, when implemented, provides a user a notification about one or more road conditions. The system may include one or more sensors that may be configured to detect the presence and absence of one or more road markings, and a processing unit in operable communication with the one or more sensors configured to receive and process a plurality of sensor readings provided by the one or more sensors. A display in operable communication with the processing unit may be configured to display audio, visual, and audiovisual notification messages to a user.
Type:
Grant
Filed:
June 26, 2018
Date of Patent:
January 12, 2021
Assignee:
PRINCESS SUMAYA UNIVERSITY FOR TECHNOLOGY
Inventors:
Yazan Ahmad Alqudah, Belal Hussein Mohammad Sababha
Abstract: An intranasal occlusion device having an inflatable balloon within a sponge that is used to prevent drainage of fluid, such as blood and other fluids into the airway during sinus and nasal minor procedures or surgeries, and methods of using the device to occlude an intranasal cavity of a patient. The device provides for suction to remove the fluid and may facilitate office-based minor procedures or surgeries.
Abstract: Devices that sense sweat and are capable of providing chronological assurance are described. The device uses at least one sensor to measure sweat or its components and to determine a sweat sampling rate. The chronological assurance is determined, at least in part, using the sweat sampling rate. The sweat sampling rate may be determined, at least in part, using a sweat volume and/or a sweat generation rate, both of which may be measured or predetermined.
Abstract: The present disclosure discloses an automated dispensing machine adopting local coverage type sucker array and a control method thereof. The automated dispensing machine adopting local coverage type sucker array comprises a rack. A medicine obtaining device and a medicine weighing and discharging device are arranged on the rack. The control method comprises: (1), after receiving medicine grasping and discharging commands, a single-chip microprocessor firstly selects a current medicine obtaining station according to a medicine obtaining station circulation sequence, and then controls the first linear driver to push the slide to move forwards to the selected medicine obtaining station; (2), the single-chip microprocessor transmits the control signal to a fifth relay to control the second linear driver to drive the vacuum medicine sucking mechanical arm to move downwards.
Type:
Grant
Filed:
April 1, 2020
Date of Patent:
January 12, 2021
Assignee:
Chongqing University
Inventors:
Yongduan Song, Zhixi Shen, Xiaohu Pan, Li Chen, Xiao Chen, Zhilin Wang
Abstract: A system and method for rip-up and re-routing a global routing solution includes determining, via processing circuitry, one or more rip-up and re-route (R&R) strategies for a net; decomposing, via the processing circuitry, multiple pins of the net into a plurality of subnets; decomposing a spanning tree of the net into paths for the plurality of subnets; determining, via the processing circuitry, a probability of success of each of the R&R strategies for one of minimizing a total overflow of a global routing solution or minimizing a wire length of the global routing solution; and applying one of the R&R strategies to the net based on the determined probability of success of said each of the R&R strategies towards improving the global routing solution, wherein the global routing solution includes a plurality of spanning trees for a respective plurality of nets of a global routing system.
Type:
Grant
Filed:
July 26, 2019
Date of Patent:
January 12, 2021
Assignee:
King Fahd University of Petroleum and Minerals