Abstract: Provided are an injectable tissue adhesive hydrogel including gamma-cyclodextrin (?-CD). When such an injectable tissue adhesive hydrogel including the ?-CD is used as a skin glue, based on a fact that the ?-CD has a bigger hydrophobic cavity than that of ?- and ?-CDs, the injectable tissue adhesive hydrogel including the ?-CD has stronger interactions than host-guest interactions. In addition, hydrogen bonding in the injectable tissue adhesive hydrogel including the ?-CD can improve both cohesiveness and adhesiveness of gelatin. The injectable tissue adhesive hydrogel including the ?-CD having excellent cell viability is used for adhesion of a skin incision, to thereby effectively promote tissue regeneration.

Abstract: The disclosure relates to improved therapeutic methods for treating cancer patients. The methods include a method for treating cancer in a subject comprising administering an effective amount of a BACH1 inhibitor and an ETC inhibitor to the subject. Further aspects of the disclosure relate to a method for treating cancer in a subject comprising: administering a first therapeutic regimen comprising an ETC inhibitor to the subject after a biological sample from the subject was determined to have a decreased or substantially the same level of expression of BACH1 relative to a control sample or to a cut-off value; wherein the first therapeutic regimen excludes a BACH1 inhibitor; or administering a second therapeutic regimen comprising a BACH1 inhibitor and an ETC inhibitor to the subject after a biological sample from the subject was determined to have an increased level of expression of BACH1 relative to a control sample or a cut-off value.

Abstract: An improved stethoscope design with an extended detection range for sounds above and below the range of human hearing and artificial intelligence connection to other clinical data for analysis, wherein the stethoscope assesses spatial distribution of bodily sounds using a sensor array as well as amplifies the volume of bodily sounds and provides for recording, receiving and processing same.

Abstract: Methods and system for producing combined photoacoustic/ultrasonic image frames use a low-power narrow beam laser to direct sequential pulses along a path overlying an internal region of interest. Photoacoustic responses are received and used to generate sub-frames. Between each of the laser pulses a plurality of ultrasound pulse-echo beams are sequentially emitted towards the region of interest, and the reflections are received and used to generate ultrasound sub-frames. The photoacoustic sub-frames are combined to produce a photoacoustic frame, and the ultrasound sub-frames are combined to produce an ultrasound frame. The photoacoustic and ultrasound frames are combined to produce an image frame. The method and system are suitable for producing real-time, high-contrast video.

Abstract: New plant growth regulators, including compounds and compositions, and methods of use including for promoting root growth. The compounds are carotenoid oxidation products, and a preferred example is 3-OH-?-apo-13-Carotenone. A method comprising promoting the growth of at least one plant with use of an effective amount of at least one composition comprising an effective amount of at least one compound which is represented by A-B-C, wherein B is a bivalent polyene moiety, A is a monovalent moiety linked to B by a six-membered carbon ring, wherein the ring has at least one substituent linked to the ring by an oxygen atom, and C is a monovalent moiety linked to B by a carbonyl group. Synergistic effects can be used with combinations of compounds.

Abstract: Disclosed is a photoreactive sensor including an optical amplification phototransistor, in which a non-overlapping region that does not overlap with a local gate electrode between a source electrode and a drain electrode is formed and which senses an optical image through the non-overlapping region for amplify photoconductivity; and a contact light emitting device that is formed on the optical amplification phototransistor and generates the optical image corresponding to a contacted surface upon contact with an object.

Abstract: The present disclosure relates to an arithmetic device that reduces a scale of an arithmetic processing unit which performs an arithmetic process between frames in a sensor. A frame memory stores pixel data of a frame that transitions in time sequence. An inter-frame arithmetic processing unit implements a predetermined arithmetic by column parallel in a row unit on the pixel data of a current frame and the pixel data of a past frame stored in the frame memory and updates the pixel data of the past frame stored in the frame memory on the basis of a result of the predetermined arithmetic.

Abstract: Disclosed are compositions and methods that include or utilize plant growth promoting rhizobacteria (PGPR) for improving growth and health in plants and animals. The compositions and methods include or utilize a plant growth promoting rhizobacteria (PGPR) that expresses a protein associated with pectin metabolism, and a saccharide comprising pectin or a pectin-related saccharide.

Abstract: Provided is a method for CT image denoising based on deep learning, and the method for CT image denoising based on deep learning includes: extracting examination information from an input CT image; selecting at least one deep learning model corresponding to the examination information from multiple previously trained deep learning models; and outputting a CT image denoised from the input CT image by feeding the input CT image into the selected at least one deep learning model.

Abstract: Provided herein are dUTPase inhibitors, compositions comprising such compounds and methods of using such compounds and compositions.

Abstract: An electronic device, such as, without limitation, a perovskite solar cell or a light emitting diode, includes an assembly including at least one electronic portion or component, and a composite coating layer covering at least part of the assembly including the at least one electronic portion or component. The composite coating layer includes a polymer material, such as, without limitation, PMMA or PMMA-PU, having nanoparticles, such as, without limitation, reduced graphene oxide or SiO2, embedded therein. The electronic device may further include a second coating layer including a second polymer material (such as, without limitation, PMMA or PMMA-PU without nanoparticles) positioned between the coating layer and the assembly.

Abstract: A method for diagnosing an active Mycobacterium tuberculosis infection by detecting certain RNA biomarkers present in secreted extracellular vesicles isolated from a bodily fluid. The RNA biomarkers in the secreted extracellular vesicles may include a certain Mycobacterium RNAs as well as certain host cell RNAs. Also provided is an RNA signature of certain Mycobacterium and host cell RNA present in secreted extracellular vesicles indicative of an active tuberculosis infection.

Abstract: Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.

Abstract: A method of separating magnetic nanoparticles is described. The method comprises placing the magnetic nanoparticles in a periodic magnetic field. The periodic magnetic field varies between a first magnetic field strength and a second magnetic field strength that is higher than the first magnetic field strength. The nanoparticles may be superparamagnetic iron oxide nanoparticles.

Abstract: A modular hydroponic tower array fixture system for the growth of organisms such as plants and fungi on arrays of hydroponic towers, allowing for the insertion and removal of individual towers from the array, is provided. Methods for the production of organisms such as plants and fungi using a modular hydroponic tower array fixture system are also provided herein.

Abstract: A monopolar physiological signal detection device and a method of operating the monopolar physiological signal detection device are provided. With a differential amplifier, a delay circuit, a driven-body circuit, and a band-pass filter, the monopolar physiological signal detection device can reduce the common-mode interference induced by supply mains. Moreover, the monopolar physiological signal detection device employs a single electrode to generate electric potentials with different time factors from the same skin surface. Accordingly, consecutive heartbeat related information of a user can be collected even when the user is under natural and comfortable postures.

Abstract: The present disclosure relates to a light emitting material for a tetradentate cyclometalated platinum complex and an application thereof in the field of OLED. The tetradentate cyclometalated platinum complex is selected from one of compounds as shown in formula I. The present disclosure adjusts the photophysical properties of the tetradentate cyclometalated platinum complex by changing the structure of a ligand surrounding a metal center or regulating and controlling the structure of a substituent on a ligand, which can emit light in a range of about 400 nm to about 700 nm and has the advantages of narrow emission spectrum, high stability and high efficiency and has a wide application prospect in the field of OLED display and illumination.

Abstract: A vestibular stimulation array is disclosed having one or more separate electrode arrays each operatively adapted for implantation in a semicircular canal of the vestibular system, wherein each separate electrode array is dimensioned and constructed so that residual vestibular function is preserved. In particular, the electrode arrays are dimensioned such that the membranous labyrinth is not substantially compressed. Furthermore, the electrode array has a stop portion to limit insertion of the electrode array into the semi-circular canal and is still enough to avoid damage to the anatomical structures.

Abstract: Provided herein are cinchonium betaine catalysts and methods of promoting asymmetric imine isomerization reactions using the same.

Abstract: Provided is a production method for a magnetoresistive element including treating a stacked layer into a predetermined shape. The stacked layer includes a magnetoresistive layer whose resistance changes depending on a magnetic field and a cap layer above the magnetoresistive layer and having a thickness in a range of 10 nm to 60 nm. The method further includes covering and protecting the stacked layer with an insulating layer, forming an opening in the insulating layer by reactive etching and exposing a surface of the cap layer at the opening, etching the cap layer in a range less than a total thickness of the cap layer by ion milling of the surface, and depositing an upper layer to be a part of the magnetoresistive element. The upper layer is in contact with the surface of the cap layer after the etching.