Abstract: The present application provides a micromechanical (MEMS) based zoom lens system, for use in miniature device applications, such as miniature electronic imaging devices. The MEMS-based zoom lens system comprises at least four optical elements, or two Alvarez or Lohmann lenses, that are configured for passage of optical signals therethrough along an optical signal path. Each optical element is MEMS-driven and displaceable in a direction substantially transverse to the optical signal path. In use, the transverse displacement of the optical elements vary an overall focal length of the MEMS zoom lens system such as to provide an optical zoom function. A method of manufacturing a MEMS zoom lens system is also provided in a further aspect.
Abstract: The present invention herein relates to a method of forming a through-hole in a silicon substrate. The present invention herein also relates to a method of forming an electrical connection element which penetrates through the silicon substrate, and to a semiconductor device manufactured thereby. More particularly, the present invention herein relates to a method of forming in a silicon substrate a through-hole capable of reducing roughness in a side wall of the through-hole and exhibiting low permittivity, by alternatingly laminating cationic and anionic polymer on the through-hole that has a dent on the side wall to form a porous elastic layer, and also relates to a method of forming an electrical connection that penetrates through the silicon substrate, and to a semiconductor device manufactured thereby.
Type:
Grant
Filed:
November 26, 2015
Date of Patent:
April 25, 2017
Assignee:
Kookmin University Industry Academy Cooperation Foundation
Abstract: The present invention relates to methods and compositions for increasing production of 3-methyl-2-butenol in a de novo synthetic pathway in a genetically modified host cell using isopentenyl disphosphate (IPP) as a substrate.
Type:
Grant
Filed:
September 13, 2012
Date of Patent:
April 25, 2017
Assignee:
The Regents of the University of California
Abstract: The invention provides methods of preventing, treating or ameliorating autoimmune diseases, such as diabetes and celiac disease, by decreasing the binding of MHC class II molecules to antigenic peptides or fragments of antigenic peptides of the autoimmune disease by the administration of small organic compounds. The invention also provides pharmaceutical compositions comprising the therapeutically effective small organic compounds and methods of using the same.
Type:
Grant
Filed:
May 29, 2012
Date of Patent:
April 25, 2017
Assignees:
The Regents of the University of Colorado, a body corporate, The University of Florida Research Foundation Incorporated
Inventors:
Aaron Michels, Maki Nakayama, David Ostrov
Abstract: To store and play contents streamed in a multimedia streaming system, an operating method of a server in the multimedia streaming system includes receiving a transmission request for a Media Presentation Description (MPD) file; and transmitting the MPD file including a flag indicating whether it is possible to generate a media file that is playable by a media file player by concatenating transmitted segments.
Type:
Grant
Filed:
January 18, 2012
Date of Patent:
April 25, 2017
Assignees:
Samsung Electronics Co., Ltd, University of Seoul Industry Cooperation Foundation
Inventors:
Sung-Ryeul Rhyu, Yong-Han Kim, Seo-Young Hwang
Abstract: A cache memory includes a tag memory array and a data memory array. A control register records a reconfiguration status of at least one cache way, a start address of the tag memory array, and a start address of the data memory array. A memory controller is electrically connected to the tag memory array, the data memory array, and the control register. The memory controller controls a data access state of the tag memory array according to the mode byte and the tag base address. The memory controller controls a data access state of the data memory array according to the mode byte and the data base address. A selection module is electrically connected between the tag memory array, the data memory array, and the memory controller. The cache memory solves the problem of idle tag memory of the tag memory array.
Type:
Grant
Filed:
May 19, 2015
Date of Patent:
April 25, 2017
Assignee:
National Sun Yat-Sen University
Inventors:
Ing-Jer Huang, Chun-Hung Lai, Yun-Chung Yang
Abstract: Disclosed are an Hsp90 inhibitor and a preparation method and use thereof. The Hsp90 inhibitor is 2-(4-(3-acetylcarnitineacyloxy)cyclohexylamino)-4-(1-(3,6,6-trimethyl-4-oxy-4,5,6,7-tetrahydroindazole))benzamide. The Hsp90 inhibitor has good water solubility and high bioavailability, and can effectively inhibit the proliferation of cancer cells, such as leukemia, cervical cancer, breast cancer, human laryngeal epithelial carcinoma, or malignant melanoma cells. It can also effectively inhibit the activity of herpes simplex virus. The maximal non-toxic concentration of the Hsp90 inhibitor on normal cells is a high, and the Hsp90 inhibitor only has specific inhibition effect on cancer cells.
Abstract: A technological method for synthesizing optically pure L-/D-lactide by using a biogenic guanidine catalysis method. The method of the present invention comprises: by using biogenic guanidine creatinine (CR) as a catalyst and L-/D-lactic acid (90% of mass content) as a raw material, synthesizing optically pure L-/D-lactide by using a reactive reduced pressure distillation catalysis method.
Type:
Grant
Filed:
August 17, 2013
Date of Patent:
April 25, 2017
Assignee:
Nanjing University
Inventors:
Hong Li, Quanxing Zhang, Na Cheng, Tianrong Zhang, Wei Jiang, Wei Huang, Bingcai Pan
Abstract: A nanostructure layer includes a number of nanostructures, wherein the number of nanostructures are aligned along a number of straight lines, a size of each of the number of nanostructures ranges from about 20 nanometers to about 100 nanometers, a distance between adjacent two nanostructures ranges from about 10 nanometers to about 300 nanometers, and each of the number of nanostructures includes a core and a shell coated on the core. A light emitting diode with the nanostructure layer is also provided.
Type:
Grant
Filed:
November 21, 2014
Date of Patent:
April 25, 2017
Assignees:
Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
Inventors:
Yuan-Hao Jin, Qun-Qing Li, Shou-Shan Fan
Abstract: An apparatus, a method, and a recorded medium for conductivity and susceptibility reconstruction are disclosed. The apparatus for conductivity and susceptibility reconstruction includes: a susceptibility reconstruction part configured to reconstruct a susceptibility from a change in phase according to an increase in time of a multi-echo gradient echo image; a zero echo phase estimation part configured to estimate a phase at zero echo time based on a linearity of the phase change; and a conductivity reconstruction part configured to reconstruct a conductivity from the estimated zero echo phase. According to an embodiment of the invention, a multi-echo gradient echo sequence is used to not only obtain in vivo susceptibility but also obtain conductivity simultaneously. Also, an embodiment of the invention can improve the accuracy of the susceptibility measurements.
Type:
Grant
Filed:
May 3, 2013
Date of Patent:
April 25, 2017
Assignee:
Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
Dong-Hyun Kim, Narae Choi, Sung-Min Gho, MinOh Ghim, Joonsung Lee
Abstract: A neutron imaging system, including: a plurality of Li-III-VI2 semiconductor crystals arranged in an array, wherein III represents a Group III element and VI represents a Group VI element; and electronics operable for detecting and a charge in each of the plurality of crystals in the presence of neutrons and for imaging the neutrons. Each of the crystals is formed by: melting the Group III element; adding the Li to the melted Group III element at a rate that allows the Li and Group III element to react, thereby providing a single phase Li-III compound; and adding the Group VI element to the single phase Li-III compound and heating. Optionally, each of the crystals is also formed by doping with a Group IV element activator.
Type:
Grant
Filed:
March 31, 2014
Date of Patent:
April 25, 2017
Assignees:
Consolidates Nuclear Security, LLC, Fisk University
Abstract: An axial flow blood pump comprises: an impeller (2) that rotates around an axis and is provided with axial flow blades on the peripheral surface thereof, a permanent magnet inside the impeller (2), and a dynamic bearing or a pivot bearing; a first casing (5) that surrounds the peripheral surface of the impeller (2) and is provided with an intake port (11); an annular fixed element (6) that generates a rotating magnetic field in the impeller (2) and can be fitted onto the outer surface of the first casing (5); an outlet port (12); a second casing (3) that is provided with guide vanes (diffusers) (31) in the inner surface thereof; and a socket member (4) that is fittably and securely mounted onto the outer peripheral surface of the second casing (3) and is provided with a joining portion that can join with the fixed element (6).
Type:
Grant
Filed:
December 26, 2013
Date of Patent:
April 25, 2017
Assignee:
National University Corporation Kobe University
Abstract: Systems and methods for a positron emission tomography (PET) kit are described. A PET detector kit may include a gantry, a plurality of PET detector modules, and an event processing device. A PET detector module may include a housing, a crystal, a light detector, and a communication component. The housing may include at least one connective element configured to removably and adjustably couple the PET detector module to the gantry. The crystal may be located within the housing. The light detector may be configured to detect light emitted by the crystal. The communication component may be configured to communicate data from the at least one light detector to an event processing device. The event processing device may receive data from the plurality of PET detector modules and may cause the one or more processors to determine coincidence events based on the received data.
Type:
Grant
Filed:
June 12, 2014
Date of Patent:
April 25, 2017
Assignee:
The Regents of the University of California
Inventors:
Ramsey D. Badawi, Simon Cherry, Felipe Godinez, Jonathan Poon, Martin Judenhofer, Jinyi Qi, Abhijit Chaudhari, Madagama Sumanasena, Julien Bec
Abstract: The present invention relates to a method for manufacturing a three-dimensional (3D) biomimetic scaffold that exploits the use of electrical fields and electrical insulating materials to pattern previously polymerized hydro gels with different molecules and/or macromolecular entities. The invention also relates to the 3D-biomimetic scaffolds obtained and to the uses and applications thereof.
Type:
Grant
Filed:
January 25, 2013
Date of Patent:
April 25, 2017
Assignee:
Queen Mary University of London
Inventors:
Alvaro Mata Chavarria, Juan Pablo Aguilar
Abstract: DNA constructs as well as methods for the production of unicellular organisms capable of producing hydrogen peroxide resistance proteins are disclosed. DNA constructs as well as methods for integration of the DNA constructs into the genomes of unicellular organisms for the expression of hydrogen peroxide production proteins are also disclosed. In addition, DNA constructs as well as methods for integration of the DNA constructs into the genomes of unicellular organisms for the expression of hydrogen peroxide resistance and hydrogen peroxide production proteins are disclosed.
Abstract: The present invention provides a synthetic regulator of protein function, which regulator is a light-sensitive regulator. The present invention further provides a light-regulated polypeptide that includes a subject synthetic regulator. Also provided are cells and membranes comprising a subject light-regulated polypeptide. The present invention further provides methods of modulating protein function, involving use of light. The present invention further provides methods of identifying agents that modulate protein function.
Type:
Grant
Filed:
January 8, 2015
Date of Patent:
April 25, 2017
Assignee:
The Regents of the University of California
Inventors:
Ehud Y. Isacoff, Richard H. Kramer, Dirk Trauner, Matthew R. Banghart, Matthew Volgraf, Pablo Ignacio Gorostiza Langa, Katharine Borges
Abstract: An object of the present invention is to provide methods for preventing or treating a steroid-resistant or steroid-dependent inflammatory bowel disease. The object can be achieved by a method for preventing or treating a steroid-resistant or steroid-dependent inflammatory bowel disease in a patient in need of the prevention or treatment of the inflammatory bowel disease, comprises administering an effective amount of adrenomedullin, a modified product thereof having an activity of suppressing steroid-resistant or steroid-dependent inflammation, or a salt thereof having an activity of suppressing steroid-resistant or steroid-dependent inflammation, to the patient.
Type:
Grant
Filed:
January 12, 2012
Date of Patent:
April 25, 2017
Assignee:
University of Miyazaki
Inventors:
Kazuo Kitamura, Shinya Ashizuka, Haruhiko Inatsu, Toshihiro Kita
Abstract: A heterocyclic compound of Formula 1 below and an organic light-emitting device including the same are provided. X1 to X4, L1, L2, n, m, and Ar1 to, Ar4 in Formula 1 are defined as in the specification.
Type:
Grant
Filed:
March 24, 2014
Date of Patent:
April 25, 2017
Assignees:
Samsung Display Co., Ltd., Seoul National University R&DB Foundation
Inventors:
Se-Hun Kim, Mi-Kyung Kim, Jong-In Hong, Dong-Hyun Kim, Seong-Jin Jeong, Hwan-Hee Cho, Chang-Woong Chu