Abstract: The present invention provides wellbore pressure control system and method for well cementation stages, and relates to the offshore oil and gas exploitation field. The wellbore pressure control system comprises: an injection pump; and a control device, configured to control the injection pump to inject a fluid or gas through an injection pipeline to a return pipeline that communicates with an annular space of the wellbore to decrease the pressure in the return pipeline and thereby decrease the pressure in the annular space, wherein, the density of the fluid or gas is lower than the density of a drilling fluid in the annular space. The technical scheme of the present invention can effectively prevent leaky zones from being fractured by high-density cement slurry in the well cementation process that may cause safety accidents such as well kick and well blowout, etc.

Abstract: Provided is a biological membrane including at least one ring-like polypeptide, where the at least one of the ring-like polypeptide is not a membrane protein, a surface being associated with at least one ring-like polypeptide capable of integration into a cell membrane, an electrode including said surface and electronically and biomedical devices including the electrodes for recording and stimulating cell activity.

Abstract: A concrete product is produced by providing red dune sand having a particle size of 45 microns or less and mixing the red dune sand with hydraulic cement in a ratio of about 30% of the cement being replaced by the red dune sand. The cement and red dune sand are then mixed with fine and course aggregate, water and a superplasticizer and cast after pouring into a mold cavity. Then within 24 hours of casting, the cast article is steam cured for 12 hours under atmospheric pressure, demolded and placed in an auto clave at 100% humidity. The temperature in the auto clave is raised to 180° C. within one to two hours and maintained at that temperature for 4 to 5 hours. The temperature also increases the pressure to about 10 bars. The pressure is released to reach atmospheric pressure within 20-30 minutes and the temperature reduced gradually, so that the article can be removed.

Abstract: A method for treating tau-associated disease by administering a pharmaceutical composition comprising a quinoline derivative to a subject in need is disclosed. Particularly, a method for treating Alzheimer's disease by administering a pharmaceutical composition comprising a quinoline derivative to a subject in need is disclosed. The two disclosed quinoline derivatives have the inhibition effect for GSK-3? kinase activity, so as the two disclosed quinoline derivatives have the ability for inhibiting tau hyperphosphorylation or reducing tau aggregation.

Abstract: A memory circuit (100) includes a plurality of memory cells (50), an N-type MOSFET (30a) and an N-type MOSFET (30b). The drain of the N-type MOSFET (30a) is connected to one of a pair of bit lines, and the drain of the N-type MOSFET (30b) is connected to the other of the pair of bit lines. The gate of the N-type MOSFET (30a) is connected to the drain of the N-type MOSFET (30b), and the gate of the N-type MOSFET (30b) is connected to the drain of the N-type MOSFET (30a).

Abstract: The invention described herein provides an energy transfer system via a tire based inductor system. By using the tire, the area inside the tire, the tire rim, or the wheel as the inductive pick-up for a powered roadway system the prior art problems are solved. Namely, since the tire/wheel is always in contact, or near contact with the road, the air gap is reduced to a minimum, and substantially fixed, distance. By mounting the secondary on the perimeter of a wheel, relative motion between the road and inductor is minimized. In addition, the pick-up can be encased in the tire, eliminating the problem of road debris, snow and ice entirely. Also, some heating of the tire due to electrical losses may enhance traction and tread performance on snowy or wet roads. In all configurations, the vehicle's wheel suspension adjusts vertically adjusting for road imperfections and obstacles.

Abstract: Provided is an optical microscope capable of maintaining an objective lens in a focus state without adversely affecting a captured image even when a substance with a weak emission is used as an observation target object. The optical microscope includes an observation optical system capable of capturing, with an image pickup device (10), an optical image of an observation target object (1) that has been obtained with an objective lens (5), and sending out the optical image as an image signal; and an autofocus device that adjusts a focal position of the objective lens based on autofocus light emitted from a focusing light source (11) so as to focus on the observation target object, wherein the autofocus light is emitted from the focusing light source during a non-capturing period during which the image pickup device is not capturing an image of the observation target object.

Abstract: A method for cardiac motion estimation includes: receiving a set of echocardiographic images of a heart, the echocardiographic images including B-mode ultrasonic images and Tissue Doppler Imaging (TDI) images; and calculating, by the image processing machine, a motion field representing the motion of the heart using the B-mode ultrasonic images and applying a velocity constraint from the TDI images. A system for cardiac motion estimation, includes: an imaging device configured to acquire a set of echocardiographic images of a heart, the echocardiographic images including B-mode ultrasonic images and TDI images; a data storage device in communication with the imaging device and configured to store the set of echocardiographic images; an image processing machine in communication with the data storage device and configured to calculate a motion field representing the motion of the heart using the B-mode ultrasonic images and applying a velocity constraint from the TDI images.

Abstract: The present invention provides a method for processing a shared file and a cloud storage server. The method comprises: receiving, by a cloud storage server, an update request message from a second client; determining that a first file is located within a storage region of a first client according to an identifier of the first file and acquiring current version information of the first file from the storage region of the first client; and if it is determined that the version of the first file on the second client is older than the version of the first file within the storage region of the first client, generating a first download address and transmitting the first download address to the second client, so that the second client downloads the first file in the current version. According to an embodiment of the present invention, it is able to synchronously update the shared file.

Abstract: Disclose is a gait recognition method, firstly, extracting an initial gait feature of a gait video of a person to be recognized; secondly obtaining a corresponding optimized gait feature according to a trained sub neural network and the initial gait feature; then determining corresponding degrees of similarity according to the optimized gait feature of the person to be recognized and the optimized gait feature of each known person in a matching library, and determining information of the person to be recognized according to information of the known person in the matching library corresponding to the optimized gait feature which has the highest degree of similarity with the optimized gait feature of the person to be recognized.

Abstract: Provided is the discovery of the role of EphA4 signaling in neurodegenerative disorders involving ?-amyloid induced neurotoxicity such as Alzheimer's Disease. New therapeutic methods, therapeutic agents, and kits for treating diseases caused or exacerbated by overactivated EphA4 signaling are provided. Also provided are methods for identifying additional compounds as therapeutic agents useful for treating conditions involving overly active EphA4 signaling.

Abstract: A device including an array of aligned conductive channels. The conductive channels are operable for directional transport of species selected from the group consisting of electrons, ions, phonons, and combinations thereof. The conductive channels are provided for by nanofibers in a form selected from the group consisting of ribbons, sheets, yarns, and combinations thereof.

Abstract: In alternative embodiments, the invention provides compositions and methods for overcoming or diminishing or preventing Growth Factor Inhibitor resistance in a cell, or, a method for increasing the growth-inhibiting effectiveness of a Growth Factor inhibitor on a cell, or, a method for re-sensitizing a cell to a Growth Factor Inhibitor, comprising for example, administration of a combination of a TBK1 inhibitor and an RTK inhibitor. In alternative embodiments, the cell is a tumor cell, a cancer cell or a dysfunctional cell.

Abstract: A method for producing highly reactive olefin polymers wherein at least 50 mol. % of the polymer chains have terminal double bonds, and a novel polymerization initiating system for accomplishing same.

Abstract: Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 ?m resolution for an image of the field of view.

Abstract: A suspended nanotube film (or films) producing sound by means of the thermoacoustic (TA) effect is encapsulated between two plates, at least one of which vibrates, to enhance sound generation efficiency and protect the film. To avoid the oxidation of carbon nanotubes at elevated temperatures and reduce the thermal inertia of surrounding medium the enclosure is filled with inert gas (preferably with high heat capacity ratio, ?=Cp/Cv, and low heat capacity, Cp). To generate sound directly as the first harmonic of applied audio signal without use of an energy consuming dc biasing, an audio signal modulated carrier frequency at much higher frequency is used to provide power input. Various other inventive means are described to provide enhanced projected sound intensity, increased projector efficiency, and lengthened projector life, like the use of infrared reflecting coatings and particles on the projector plates, non-parallel sheet alignment in sheet stacks, and cooling means on one projector side.

Abstract: A tunnel field-effect transistor (TFET) is configured by disposing a III-V compound semiconductor nano wire on a (111) plane of a IV semiconductor substrate exhibiting p-type conductivity, and arbitrarily disposing electrodes of a source, drain and gate. Alternatively, the tunnel field-effect transistor is configured by disposing a III-V compound semiconductor nano wire on a (111) plane of a IV semiconductor substrate exhibiting n-type conductivity, and arbitrarily disposing electrodes of a source, drain and gate. The nano wire is configured from a first region and a second region. For instance, the first region is intermittently doped with a p-type dopant, and the second region is doped with an n-type dopant.

Abstract: Novel organic compounds comprising ligands with deuterium substitution are provided. In particular, the compound is an iridium complex comprising methyl-d3 substituted ligands. The compounds may be used in organic light emitting devices to provide devices having improved color, efficiency and lifetime.

Abstract: Disclosed are methods for diagnosing declarative memory loss using mouse tracking to follow the visual gaze of a subject taking a visual paired comparison test. Also disclosed are methods for diagnosing dementia such as mild cognitive impairment and Alzheimer's disease.

Abstract: Methods for classifying and for evaluating the prognosis of a subject having breast cancer are provided. The methods include prediction of breast cancer subtype using a supervised algorithm trained to stratify subjects on the basis of breast cancer intrinsic subtype. The prediction model is based on the gene expression profile of the intrinsic genes listed in Table 1. This prediction model can be used to accurately predict the intrinsic subtype of a subject diagnosed with or suspected of having breast cancer. Further provided are compositions and methods for predicting outcome or response to therapy of a subject diagnosed with or suspected of having breast cancer. These methods are useful for guiding or determining treatment options for a subject afflicted with breast cancer.