Abstract: Anti-human B7-H4 antibody “6H3”, antigen-binding fragments, derivatives, and humanized variants thereof that are capable of immunospecifically binding to B7-H4, and the uses of such molecules in the diagnosis and the treatment of cancer and other diseases are disclosed. In preferred embodiments, the molecules are used to retard or prevent tumor growth, inhibit tumor-mediated suppression, eliminate tumors and/or deplete or block the activity of tumor-associated macrophages (“TAMs”) so as to alter their activity and/or decrease TAM-mediated immune suppression.

Abstract: The present invention relates to methods inhibiting tumor metastasis and treating cancer in a subject that involve administering to the subject an antibody which recognizes GPIIIa49-66, under conditions effective to inhibit tumor metastasis and/or treat cancer in the subject.

Abstract: A novel Rh(I)-catalyzed approach to synthesizing functionalized (E,Z) dienal compounds has been developed via tandem transformation where a stereoselective hydrogen transfer follows a propargyl Claisen rearrangement. Z-Stereochemistry of the first double bond suggests the involvement of a six-membered cyclic intermediate whereas the E-stereochemistry of the second double bond stems from the subsequent protodemetallation step giving an (E,Z)-dienal. The reaction may be represented by the following sequence.

Abstract: A conductive thin film, a transparent electrode, and methods of producing the same are provided. A method for preparing a conductive thin film may involve forming a layer of reduced graphene oxide and carbon nanotube on a substrate using a reducing agent containing a halogen atom.

Abstract: A wireless charging system for a vehicle may include: a power transmitter having a plurality of transmitting coils; and a controller configured to measure a current and a voltage of each of the plurality of transmitting coils and to apply charging power only to a subset of the plurality of transmitting coils based on a magnitude of the measured current and voltage of each of the plurality of transmitting coils.

Abstract: The present disclosure relates to a metal oxide-carbonaceous hybrid thin film, a preparing method of the metal oxide-carbonaceous hybrid thin film, and a dye-sensitized solar cell using a photoelectrode including the metal oxide-carbonaceous hybrid thin film.

Abstract: The present disclosure relates to a method to enhance the efficiency and reduce interfacial charge transfer resistance in dye sensitized solar cell (DSSC) and a perovskite solar cell (PSC) by fabricating with Mg and La doped photoanodes. Mg and La co-doped into TiO2 has shown more than 20% efficiency than pristine TiO2 and more than 5% higher efficiency than the single doping of 1% La and Mg in TiO2 cells. Thus, the present disclosure relates to an improved photoanode material to be used in solar cells.

Abstract: A novel method for real-time small-signal stability analysis for power electronic-based components in a power system. The method may be used to monitor a power system in real-time by perturbing the source side of an electronic-based component of the power system by injecting a current of about 0.5 to 1 percent of a nominal current of the power system at the source side, while simultaneously perturbing the load side of the power electronic-based component by varying the voltage at the load side. Time-domain results of the simultaneous perturbations may be transferred to frequency-domain results and the stability of the power system may be monitored by obtaining a Nyquist contour and employing Generalized Nyquist Criterion or unit circle criterion.

Abstract: Example apparatuses and methods for cancellation of transmitter self-interference leakage in a transceiver are described. An example transceiver includes a multiport transformer that may be used as a part of the impedance matching network on the receiver side of the transceiver. One primary port of the multiport transformer may form a portion of a cancellation circuit that, along with other components in a cancellation path, provide amplitude and/or phase modulation to a cancellation signal. The cancellation circuit may tunable and may include only reactive components in some examples.

Abstract: Disclosed are systems implementing an implicit Feed-Forward Compensated (FFC) op-amp, where the main FFC port is realized by the P-side of the CMOS input structure of the 2nd and 3rd stages of the op-amp, while the main signal path is through the N-side. According to some embodiments, to balance the relative strengths of the main path and feed-forward paths, the 2nd-stage NMOS input pair is split into two pairs, one is used to route the main path while the other is used for auxiliary FFC. The disclosed implicit FCC op-amp is unconditionally stable with adequate phase lead. According to some embodiments, the disclosed op-amp, which may be a wide-band op-amp, can be used in highly linear applications operative at intermediate frequency (IF), such as signal buffers for high-performance data converters or radio-frequency (RF) modulators and demodulators, continuous-time (CT) filters or sigma-delta data converters.

Abstract: The invention relates to of analyzing vector supernatants useful for transducing T cells destined for administration to a human subject. The invention also related to methods of analyzing transduced T cells destined for administration to a human subject.

Abstract: Functionalized fluorine containing phthalocyanine molecules, methods of making, and methods of use in diagnostic applications and disease treatment are disclosed herein. In some embodiments, the fluorine containing phthalocyanine molecules are functionalized with a reactive functional group or at least one cancer-targeting ligand (CTL). The CTL can facilitate more efficient binding and/or internalization to a cancer cell than to a healthy cell. The CTL can inhibit expression of oncoprotein in some embodiments. The pthalocyanine moiety can be used in diagnostic applications, such as fluorescence labeling of a cancer cell, and/or treatment applications, such as catalyzing formation of a reactive oxygen species (ROS) which can contribute to cell death of a cancer cell.

Abstract: A sensing system includes a processing unit and sensor chip. The sensor chip includes a microelectrode array, a droplet space over the microelectrode array, and a plurality of control units coupled together in a daisy-chain configuration. Each of the control units is coupled to a respective one of the microelectrodes of the microelectrode array. The control units are controlled by the processing unit to drive movement of a droplet in the droplet space, and to inspect the droplet via the microelectrodes.

Abstract: Methods, media, and systems for detecting attack are provided. In some embodiments, the methods include: comparing at least part of a document to a static detection model; determining whether attacking code is included in the document based on the comparison of the document to the static detection model; executing at least part of the document; determining whether attacking code is included in the document based on the execution of the at least part of the document; and if attacking code is determined to be included in the document based on at least one of the comparison of the document to the static detection model and the execution of the at least part of the document, reporting the presence of an attack.

Abstract: A diagnostic device is provided that comprises a light source for transmitting a light beam through a blood sample to a light detector, and a permanent magnet, wherein one of the permanent magnet and blood sample is automatically movable relative to the other between a “HIGH” magnetic state position and a “LOW” magnetic state position, such that a substantially high magnetic field is applied to the blood sample causing any hemozoin in the blood sample to tend toward perpendicular orientation to the substantially magnetic field and the suppression, or enhancement of light based on its polarization, and a zero-to-near-zero magnetic field is applied to the blood sample causing the randomization of any hemozoin in the blood sample and a baseline amount of light to pass through the blood sample in the “LOW” magnetic state position.

Abstract: A method for producing a high-strength magnesium alloy material includes (a) a step of preparing a magnesium alloy workpiece having a top face and a side face; and (b) a step of applying a compressive load ?p (MPa) from the top face side of the workpiece and performing a uniaxial forging process on the workpiece. Step (b) is performed while suppressing deformation of the workpiece widening outward and under conditions including (i) ?p>?f (where ?f is the compressive breaking stress (MPa) of the workpiece); (ii) a plastic deformation rate is less than or equal to 10%, and (iii) a strain rate is less than or equal to 0.1/sec.

Abstract: A log saw machine includes a first arm, a second arm parallel to the first arm, a shaft having a first end and an opposite second end, and a circular knife fixed on the shaft. The first end of the shaft is rotatably installed on the first arm. The second end of the shaft is rotatably installed on the second arm. The circular knife is positioned between the first and second arms, and the plane of the circular knife is parallel to the extending direction of the first and second arms.

Abstract: Insulin analogs comprising a non-native glycosylation site sequence are provided having high potency and specificity for the insulin receptor. In one embodiment a peptide sequence of greater than 18 amino acids is used as a linking moiety to link human insulin A and B chains, or analogs or derivatives thereof, to provide high potency single chain insulin analogs. In one embodiment the linking moiety comprises one or more glycosylation sites. Also disclosed are prodrug and conjugate derivatives of the insulin analogs.

Abstract: The presently disclosed and/or claimed inventive concept(s) relates generally to retro-aldol reaction products and methods of making and using same. More particularly, but without limitation, the methods disclosed herein for producing the retro-aldol reaction products are performed in a non-aqueous/solvent-free based process. The reaction products obtained from the process include, for example, dihydroxyacetone, glyceraldehyde, glycolaldehyde, and combinations thereof. In one particular embodiment, the process of making such retro-aldol reaction products includes, without limitation, the step of mechanocatalytically reacting a heterogeneous catalyst with one or more sugar reactants.

Abstract: Provided are compounds, compositions and methods for inhibiting fascin activity or treating a condition or disorder mediated by fascin activity in a subject in need thereof.