Abstract: Provided is an organic ligand-bound metal surface that selects one gaseous species over another. The species can be closely sized molecular species having less than 1 Angstrom difference in kinetic diameter. In one embodiment, the species comprise carbon monoxide and ethylene. Such organic ligand-bound metal surfaces can be successfully used in gas phase separations or purifications, sensing, and in catalysis.

Abstract: Current approaches for treating cancer are limited, in part, by the inability of drugs to affect the poorly vascularized regions of tumors. We have found that spores of anaerobic bacteria in combination with agents which interact with microtubules can cause the destruction of both the vascular and avascular compartments of tumors. Two classes of microtubule inhibitors were found to exert markedly different effects. Some agents that inhibited microtubule synthesis, such as vinorelbine, caused rapid, massive hemorrhagic necrosis when used in combination with spores. In contrast, agents that stabilized microtubules, such as the taxane, docetaxel, resulted in slow tumor regressions that killed most neoplastic cells. Remaining cells in the poorly perfused regions of tumors could be eradicated by sporulated bacteria.

Abstract: In one aspect, a method and apparatus for detecting subject matter of interest in view data obtained by scanning an object including generating a filter adapted to respond to the subject matter of interest, splatting the filter onto a portion of the view data to provide a filter splat, and performing at least one operation on the portion of the view data using the filter splat to facilitate determining whether the subject matter of interest is present in the portion of the view data.

Abstract: The present invention provides three-component compositions comprising microparticles, a tumor antigen, a first immune adjuvant, and a second immune adjuvant. Also provided are chemo-immunotherapeutic compositions comprising microparticles, a chemotherapeutic agent, and an immune adjuvant.

Abstract: The present invention provides compounds which can regulate VCP activity. The present invention provides the compound of formula (I) (R is as defined in the description) or oxides, esters, prodrugs, pharmaceutically acceptable salts or solvates thereof. The compounds can regulate VCP activity, and thus are useful for treating VCP-mediated diseases such as neurodegenerative diseases.

Abstract: An ST-MRAM structure, a method for fabricating the ST-MRAM structure and a method for operating an ST-MRAM device that results from the ST-MRAM structure each utilize a spin Hall effect base layer that contacts a magnetic free layer and effects a magnetic moment switching within the magnetic free layer as a result of a lateral switching current within the spin Hall effect base layer. This resulting ST-MRAM device uses an independent sense current and sense voltage through a magnetoresistive stack that includes a pinned layer, a non-magnetic spacer layer and the magnetic free layer which contacts the spin Hall effect base layer. Desirable non-magnetic conductor materials for the spin Hall effect base layer include certain types of tantalum materials and tungsten materials that have a spin diffusion length no greater than about five times the thickness of the spin Hall effect base layer and a spin Hall angle at least about 0.05.

Abstract: An electrical power converter includes a circuit with a single switching transistor that is electrically connected to a direct current power source, a first inductor-capacitor (LC) circuit electrically connected to the single switching transistor, a second LC circuit electrically connected to the first LC circuit and configured to provide an output signal to a load. A controller is operatively connected to the single switching transistor. The controller identifies an error between the output signal of the circuit and a reference signal and adjusts a duty cycle of a pulse width modulation (PWM) switching signal to switch the single switching transistor at a predetermined frequency with the adjusted duty cycle to reduce the identified error.

Abstract: OLEDs containing a stacked hybrid architecture including a phosphorescent organic emissive unit and two fluorescent organic emissive units are disclosed. The stacked hybrid architecture includes a plurality of electrodes and a hybrid emissive stacked disposed between at least two of the electrodes. The stack contains at least three emissive units and at least two charge generation layers. At least one of the three emissive units is a phosphorescent organic emissive unit and at least two of the three emissive units are fluorescent organic emissive units. More specifically, the two fluorescent organic emissive units may be blue organic emissive units that emit light from the same or different color regions.

Abstract: A method of detecting a target within a population of molecules comprising: contacting a plurality of labeled probe molecules with the population of molecules potentially containing a target of the probe molecules; acquiring a probe specific signal emitted by said labeled probe molecules that bound to said target together with a background signal; preferentially modulating said probe specific signal by at least one of modulating said acquisition and modulating an emission of said probe specific signal; and detecting said probe specific signal over said background signal using said preferential modulation.

Abstract: Embodiments of the invention include substituted indole compounds and compositions thereof to inhibit protease activated receptor-4. Also described are methods of preparation of compositions and methods for treating diseases related to thrombotic disorders by administration of the composition.

Abstract: Gold(I) complexes of formulae [Au{P(t-Bu)3}(S2CN(CH3)2)] (1), and [Au{P(t-Bu)3}(S2CN(C2H5)2)] (2) have been prepared by the reaction of equimolar amounts of [Au{P(t-Bu)3}(Cl)] with sodium dimethyldithiocarbamate monohydrate, and sodium diethyldithiocarbamate trihydrate respectively. Both complexes (1) and (2) are iso-structural having linear geometry. These gold(I) dithiocarbamate complexes show in vitro cytotoxic activities against A549 (human lung carcinoma), HeLa (human cervical cancer) and MCF7 (human breast cancer) cell lines.

Abstract: The disclosure relates to uses of a purified or isolated lectin to kill bacteria, viruses, and other pathogens. In certain embodiments, the disclosure relates to method of treating or preventing an infection comprising administering a purified or isolated galectin to a subject in need thereof. In certain embodiments, the subject is at risk of, exhibiting symptoms of, or diagnosed with a pathogenic infection.

Abstract: A hydraulic model of the cardiovascular system for illustrating a plurality of physiological concepts and relationships including arterial compliance, venous compliance, and peripheral resistance, said model comprising: a.) a cardiac subsystem for moving a fluid in a singular direction in a closed hydraulic system; b.) an arterial subsystem for modeling arterial compliance, the arterial subsystem fluidically coupled with the cardiac subsystem to receive the fluid discharged from the cardiac subsystem; c.) a peripheral resistance subsystem for modeling peripheral resistance, the peripheral resistance subsystem fluidically coupled with the arterial subsystem to receive the fluid discharged from arterial subsystem; d.

Abstract: The present invention provides an osmotic orthodontic appliance, comprising: an actuation structure forming a hollow tube filled with a supersaturated solution; a dental aligner structure mounted on the actuation structure for fixing the actuation structure on teeth; and a pumping structure connected one end of the hollow tube, comprising a semipermeable device and a supporting structure. The osmotic orthodontic appliance of the present invention could provide steady movement and force output; it is a solution for the periodic actuation problem of conventional orthodontic appliances.

Abstract: An embodiment provides a distributed transcoding method using a plurality of servers. The method includes receiving a request for a first video file from a first terminal. The method also includes segmenting the video file based on a play time of at least portion of the video file and a performance rate of a plurality of second servers. The method also includes transmitting the segmented video file to the plurality of second servers, which includes transmitting the segmented video file of a greater size to the second server having a higher performance among the plurality of second servers and transmitting the segmented video file having a smaller size to the server having a lower performance among the plurality of second servers. The method also includes receiving a transcoded video file from the plurality of second servers. The method also includes transmitting the transcoded video files to the first terminal.

Abstract: An inputting fingertip sleeve includes a number of first wires and a number of second wires. The number of second wires and the number of first wires are crossed with each other to form a sleeve. The number of first wires includes a number of ends converged at one end point. Each of the number of the first wire includes a carbon nanotube wire structure. The sleeve includes at least one opening and a close end, the at least one opening is configured to receive a finger.

Abstract: The invention provides methods for treating obesity in a subject comprising administering an effective amount of catestatin (CST) or its equivalent to a subject afflicted with obesity so as to maintain an effective amount of circulating catestatin in the subject to promote lipolysis and oxidation of released fatty acids in both liver and adipose tissue, thereby, reducing adipose tissue weight and hence treating obesity in the afflicted subject.

Abstract: A detection device for a CT system comprises a low-energy detector assembly; and a high-energy detector assembly disposed under the low-energy detector assembly. The high-energy detector assembly comprises: a plurality of rows of high-energy detectors arranged at predetermined intervals. With the detection device, detectors and data acquisition units are greatly reduced. A high-resolution three-dimensional CT image is acquired while high-accuracy hazardous article alarm is achieved. The cost of manufacture of the system is greatly decreased while high system performance is ensured.

Abstract: A semiconductor device structure is provided. The semiconductor device structure includes a substrate. The semiconductor device structure includes a semiconductor layer over the substrate. The semiconductor layer includes a transition metal chalcogenide. The semiconductor device structure includes a source electrode and a drain electrode over and connected to the semiconductor layer and spaced apart from each other by a gap. The source electrode and the drain electrode are made of graphene.

Abstract: The present invention provides an apparatus and method for obtaining data to determine one or more characteristics of a wind flow field using one or more radars. Data is collected from the one or more radars, and analyzed to determine the one or more characteristics of the wind flow field. The one or more radars are positioned to have a portion of the wind flow field within a scanning sector of the one or more radars.