Abstract: Certain embodiments are directed to polypeptide sensors. Certain aspects of the invention are directed to polypeptides for sensing or detecting GTP and GTP concentrations. In further aspects, the polypeptide sensor can measure GTP concentrations, with high temporal and spatial resolution.

Abstract: A system using a three-coil topology for wireless power transfer is disclosed. The system comprises a primary resonator coupled to a power source, a repeater resonator and a receiver resonator. The primary resonator has a primary coil, and the repeater resonator has a repeater coil adjacent to the primary coil. The repeater coil and the primary coil are separated by a distance selected, and the repeater coil is configured, to amplify a primary-coil current by inductively generating a repeater-coil current that is substantially greater than the primary-coil current. A magnetic field contributed from both the primary-coil current and the repeater-coil current is generated while the power source needs not provide a terminal voltage across the repeater coil, thereby discouraging occurrence of voltage stress at the power source. The receiver resonator has a receiver coil, which receives the magnetic field to inductively generate a receiver-coil current for feeding to a load.

Abstract: This shape data generation method include: setting an input shape that has a simple shape that has a same topology as the target shape for a target shape that is a shape of a transformation target identified from image data; identifying first vertices that satisfy a predetermined condition including a first condition that a normal line of a certain vertex of the plural vertices crosses with the target shape, among plural vertices of the input shape; transforming the input shape so that a first vertex is moved in a direction of a normal line of the first vertex by a first distance that is shorter than a distance up to the target shape; and performing the identifying and the transforming a predetermined number of times while changing the input shape after the transforming as the input shape to be processed.

Abstract: A method of preparing nanostructured single crystal silver, comprising placing a high-conductive molded porous active carbon containing chloride ions, which has been reductively treated, into a silver-containing precursor solution. After several hours at room temperature, the nanostructured single crystal silver grows on the surface of the active carbon. The silver-containing precursors and appropriate amount of chlorine provide a crystal nucleus and a slow stable crystal growth environment which are required for single crystal silver growth, and said nanostructured silver single crystals could be obtained with various morphologies by controlling the concentration of the silver-containing precursor solution and the growth time.

Abstract: The present invention relates to a method for preparing a diamond carbon membrane on a surface of stainless steel, including: immersing the pretreated stainless steel into a solution of a biomass-derived carbonaceous mesophase in ethanol for several minutes, prior to taking out and air drying; or alternatively, spraying the solution of the biomass-derived carbonaceous mesophase in ethanol onto the stainless steel surface, to provide a layer of the biomass-derived carbonaceous mesophase film adhered on the stainless steel surface upon full volatilization of the solution on the surface; and then carrying out thermal treatment under a hydrogen atmosphere, to prepare the diamond carbon membrane on the stainless steel surface.

Abstract: Disclosed herein are compositions and methods for sequencing, analyzing, and utilizing samples such as single samples. Also disclosed herein are compositions and methods for matching together two or more sequences from a sample. Also disclosed herein are compositions and methods for expressing and screening molecules of interest.

Abstract: The present invention is directed to methods of measuring the proliferative ability of individual patient cancer stem cells. The present invention provides a method for treating a cancer patient according to an assay of the individual patient's tumor's cancer stem cell sensitivity, by measuring the proliferative ability of cancer stem cells from the patient. By the methods of the present invention it is possible to treat individual cancer stem cells presented in tumor cells. Methods of detecting and enumerating cancer stem cells in hybrid spheroids comprised of fibroblasts and tumor cells are also provided by the present invention. The present invention also contemplates a method for drug and other treatment development, wherein the effects of a drug or combination of drugs or other treatments are determined on the individual patient's cancer stem cells.

Abstract: Methods are described for screening a subject for risk of Charcot-Marie-Tooth Disease Type 2A or for diagnosing Charcot-Marie-Tooth disease or a predisposition for developing Charcot-Marie-Tooth disease in a subject, by detecting the presence or absence of a mutation in the mitofusin gene in a biological sample collected from the subject. Methods are also described for detecting the presence of a genetic polymorphism associated with Charcot-Marie-Tooth Disease Type 2A in a sample of patient nucleic acid, by amplifying a mitofusin gene sequence in the patient nucleic acid to produce an amplification product; and identifying the presence of a Charcot-Marie-Tooth Disease Type 2A associated polymorphism in the amplification product.

Abstract: This invention provides a multiscale platform for coordinating behavior using synthetic biology. The platform reduces the impact of underlying noise, making outputs more coherent and reliable at the macroscopic level.

Abstract: Provided is an image transmission apparatus in digital TV broadcasting, including: a first converter which converts added data, which are to be inserted into an image, into a pixel block; a border extender which adds an extended border area to an image area to extend the image in video data and inserts the converted added data into the extended border area; a video encoder which encodes the video data into which the border extender inserts the added data; a video decoder which decodes the video data encoded by the video encoder; and a second converter which converts the added data which are inserted as a pixel block in the video data decoded by the video decoder into original data. Accordingly, in digital TV broadcasting such as HD TV an UDTV, the added data are inserted into a hidden area, so that it is possible to transmit various types of information including contents and copyright without a deterioration in image quality.

Abstract: A first instance of a reference video is stored. A primary video and a second instance of the reference video are simultaneously received. At least one quality of experience value that infers a perceptual quality of the primary video as received by a system is generated by comparing the first instance of the reference video to the second instance of the reference video on a pixel-by-pixel, frame-by-frame, basis and determining whether each pixel and each frame contained in the first instance of the reference video are contained in the second instance of the reference video.

Abstract: The present invention provides a drought tolerance associated protein, DT1, a nucleic acid molecule encoding the DT1 protein and application thereof.

Abstract: The present invention provides AAV capsid proteins comprising modification of one or a combination of the surface-exposed lysine, serine, threonine and/or tyrosine residues in the VP3 region. Also provided are rAAV virions comprising the AAV capsid proteins of the present invention, as well as nucleic acid molecules and rAAV vectors encoding the AAV capsid proteins of the present invention. Advantageously, the rAAV vectors and virions of the present invention have improved efficiency in transduction of a variety of cells, tissues and organs of interest, when compared to wild-type rAAV vectors and virions.

Abstract: A motion vector estimation method in video encoding: First, a feature point is detected in a video frame. Next, motion estimation is performed on the feature point to obtain a motion vector of the feature point. Next, the feature point is mapped to a feature image block, and the motion vector of the feature point is used as an initial motion vector of the feature image block. Finally, a distance between each image block and the feature image block is calculated, motion estimation is performed on the image blocks in an ascending order of the distances between the image blocks and the feature image block, and an obtained motion vector of an image block is used as an initial motion vector of an image block that is adjacent to the image block and has not undergone motion estimation, until motion estimation is completed for the image blocks in the entire video frame.

Abstract: Fast processing of information represented in digital holograms is provided to facilitate generating a phase-only hologram for displaying 3-D holographic images representative of a 3-D object scene on a display device. A holographic generator component (HGC) can receive or generate visual images, comprising depth and parallax information, of a 3-D object scene. A hologram processor component can downsample an intensity image of a visual image of the 3-D object scene using a uniform or random lattice to facilitate converting the intensity image to a sparse image. The hologram processor component can generate a complex 3-D Fresnel hologram, comprising the depth and parallax information, based on the sparse image using a fast hologram generation algorithm. The hologram processor component modify the magnitude of the pixels of the complex hologram to a defined homogeneous value to facilitate converting the complex hologram to a phase-only hologram.

Abstract: Disclosed are methods of detecting and isolating CD4+ T cells latently infected with HIV as well as methods of screening for inhibitors of CD4+ T cells latently infected with HIV.

Abstract: Novel methods and devices including modified endoscopes that employ fiber optic technology and multiple extrinsic optical sensors for enablement of simultaneous determination of change rates of biological analytes in vivo with single-cell resolution. The devices employ dynamic oscillatory actuation to determine the gradient of analytes of interest along one or multiple directions with respect to the cell. The change rate or flux of the analyte of interest can be easily determined by applying the first Fick's law that relates the flux with the concentration gradient. The dual operation mode of the device markedly increases measurement sensitivity and accuracy.

Abstract: The present disclosure generally relates to the methods and compositions to efficiently analyze polymer characteristics using nanopore-based assays. Specifically disclosed is a method for generating reference signals for polymer analysis in a nanopore system, wherein the nanopore system has a multi-subunit output signal resolution. The method comprises translocating a reference sequence through a nanopore to generate a plurality of reference output signals, wherein each possible multi-subunit sequence that can determine an output signal appears only once in the reference sequence. The output signals are compiled into a reference map for nanopore analysis of an analyte polymer. Also provided are methods and compositions for calibrating the nanopore system for optimized polymer analysis.

Abstract: A method, system, and apparatus configured to use a Bayesian inference model for detecting botnets in a network is disclosed. The system and apparatus may include an event generator and a controller. The event generator may detect at least one event in received data, and provide information associated with the at least one event. The controller may receive the information associated with the at least one event, determine, using a Bayesian learning process, a Bayesian network model based on the information associated with the at least one event, and determine whether at least one host associated with the received data is a bot.

Abstract: Provided are a magnetic resistance structure, a method of manufacturing the magnetic resistance structure, and an electronic device including the magnetic resistance structure. The method of manufacturing the magnetic resistance structure includes forming a hexagonal boron nitride layer, forming a graphene layer on the boron nitride layer, forming a first magnetic material layer between the boron nitride layer and the graphene layer according to an intercalation process; and forming a second magnetic material layer on the graphene layer.