Abstract: A Neural Circuit Probe (NCP) combines a multi-electrode array (MEA) with an automated local probe, wherein the probe is positioned to interact with one or more cells, such as neurons of a neural circuit, grown on or about one or more electrodes of the multi-electrode array. The probe may interact with the cells by electrically recording signals from the multi-electrode array that are assigned to a specific one of the cells. The probe may interact with the cells by locally delivering chemicals to the cells, which transiently and reversibly modulate the electrical behavior of the cells. The probe may interact with the cells by harvesting the cells using a pipette, so that the harvested cells can be sequenced.
Type:
Grant
Filed:
October 30, 2015
Date of Patent:
November 26, 2019
Assignee:
The Regents of the University of California
Inventors:
Paul K. Hansma, Kenneth S. Kosik, Luke S. K. Theogarajan, Barney Drake, Daniel C. Bridges, Connor J. Randall, Kenneth R. Tovar
Abstract: Improved sensor assemblies are provided. More particularly, the present disclosure provides improved and highly advantageous metal oxide based sensor assemblies configured to sense low concentration of specific gases, and related methods of use. The present disclosure provides improved physical forms of metal oxide films (e.g., WOx films, CeOx films). The exemplary metal oxide films can be fabricated by a Reactive Spray Deposition Technology (RSDT). The highly advantageous films/materials can be utilized in sensor assemblies to detect simple chemical components of the breath that correlate with human health conditions (e.g., the presence of acetone in diabetic patients). These films/materials demonstrate improved thermal stability under the sensor's operating conditions, as well as improved sensitivity to low concentration of the analyte, selectivity and quick responsiveness.
Abstract: A plasma process monitoring device capable of monitoring plasma light distributed in a certain area in a chamber includes a selection area light transmitter and a monitor. The selection area light transmitter is disposed to face a viewport formed in a chamber and includes a plurality of selective light blockers for selectively blocking plasma light emitted through the viewport. The monitor receives plasma light transmitted through at least one of a plurality of selective light blockers to acquire information on the plasma light, and monitors the uniformity of plasma generated in the chamber based on the information on the plasma light.
Type:
Application
Filed:
May 15, 2019
Publication date:
November 21, 2019
Applicant:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
Abstract: A method for image reconstruction may include: obtaining a plurality of sets of scan data captured by a magnetic resonance imaging (MRI) device, each set of scan data corresponding to a same scanning area of an object and corresponding to a plurality of scanning characteristics; generating one or more shareable data sets based on the plurality of sets of scan data; generating, based on the one or more shareable data sets, at least one optimized data set for each of the plurality of scanning characteristics; and reconstructing, based on at least one optimized data set for at least one of the plurality of scanning characteristics, the plurality of sets of scan data to obtain a reconstructed image for the at least one scanning characteristic.
Type:
Application
Filed:
June 29, 2018
Publication date:
November 21, 2019
Applicants:
SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD., SUNGKYUNKWAN University
Inventors:
Jaeseok PARK, Hyunkyung MAENG, Eunji LIM, Guobin LI, Chaohong WANG
Abstract: A method of treating a vessel in a subject comprises the steps of advancing a device distally across a treatment zone in a vessel, wherein the device comprises an elongated catheter having a lumen and a distal end, and a radially expansive treatment element disposed in the lumen and configured for axial movement relative to the catheter; deploying the radially expansive treatment element proud of the distal end of the catheter to radially expand and circumferentially impress against the vessel lumen at a distal end of the treatment zone; and withdrawing the deployed radially expansive treatment element proximally along the treatment zone with the treatment element circumferentially impressed against the vessel lumen to mechanically and circumferentially denude the treatment zone of the vessel. The radially expansive treatment element is then recaptured into the lumen of the catheter, before the device is withdrawn from the treated vessel.
Type:
Application
Filed:
May 20, 2019
Publication date:
November 21, 2019
Applicant:
National University of Ireland, Galway
Inventors:
Sean CUMMINS, Nigel PHELAN, Stephen COX, Martin O'HALLORAN
Abstract: An oil-based mud wellbore imaging apparatus for measuring formation permittivity and resistivity includes a reflectometry-type microwave scanning system. The system contains at least one high-Q microstrip resonator with one or more slots on the top surface. The microstrip resonator is excited by one port, which is fed with electromagnetic signals by a coaxial cable. From the phase detection of signal at the port, the formation resistivity and permittivity can be determined and corresponding borehole images can be generated.
Type:
Application
Filed:
January 10, 2018
Publication date:
November 21, 2019
Applicant:
University of Houston System
Inventors:
Jiefu CHEN, Xinyu LIU, David R. JACKSON
Abstract: A interply hybrid composite based single crystal alpha-aluminium oxide fiber includes single crystal alpha-aluminium oxide fiber, glass fiber and a resin compatibilizer; a hybrid ratio of the single crystal alpha-aluminium oxide fiber to the glass fiber is 1:40 to 3:53.
Type:
Application
Filed:
July 6, 2018
Publication date:
November 21, 2019
Applicants:
Research Institute of Tsinghua University in Shenhen, Tsinghua Innovation Center in Dongguan
Inventors:
Shishan JI, Renchen LIU, Yan LIU, Qing MA, Zhen HE, Zuoyu SHI
Abstract: The disclosure provides helix grafted proteins, methods of producing helix grafted proteins and methods of use of helix grafted proteins as inhibitors of protein-protein interactions involved in disease pathogenesis.
Type:
Application
Filed:
August 7, 2019
Publication date:
November 21, 2019
Applicant:
Colorado State University Research Foundation
Inventors:
Brian R. McNaughton, Susanne N. Walker, Rachel L. Tennyson, Alan J. Kennan
Abstract: An immobilization apparatus having at least one or more straps that engage a surface; wherein at least one of the straps comprises a force gauge to determine the amount of force applied to a patient immobilized with said straps; wherein the position of the patient is replicable for treatment of radiation and other head or neck treatments.
Type:
Application
Filed:
January 22, 2018
Publication date:
November 21, 2019
Applicant:
Thomas Jefferson University
Inventors:
Hyun Kim, Voichita Bar Ad, Amy Taylor, Shivank Garg
Abstract: A desalination and climate control system including a vapor-compression system having an evaporator, a condenser, and a working fluid that circulates between the evaporator and the condenser to transfer heat from the condenser to the evaporator, and a desalination system coupled with the desalination system having a humidifier that encloses the condenser, receives air and saline fluid, passes the saline fluid through the condenser to extract the heat and vaporizes the saline to provide humidified air and brine fluid, and a dehumidifier that encloses the evaporator, condensates the humidified air, and provides the air and demineralized fluid.
Type:
Application
Filed:
May 15, 2018
Publication date:
November 21, 2019
Applicant:
King Fahd University of Petroleum and Minerals
Inventors:
Mohamed A. ANTAR, Dahiru Umar Lawal, Atia Khalifa, Syed M. Zubair, Fahad Al-Sulaiman
Abstract: A system containing a reactor vessel including zero valent iron media, a source of a conditioning additive, a source of a reaction additive, and a process control subsystem is disclosed. A method for reducing a concentration of one or more contaminants in contaminated water including contacting zero valent iron media with a conditioning additive, contacting contaminated water with conditioned zero valent iron media, and introducing a reaction additive is also disclosed. The conditioning additive and reaction additive may each contain an aluminum salt.
Type:
Application
Filed:
July 31, 2019
Publication date:
November 21, 2019
Applicants:
The Texas A&M University System, Evoqua Water Technologies LLC
Inventors:
Yongheng Huang, Michael Wismer, Lew Andrew Reyes, Xiangyi Qiao, Simon Dukes, Frank Sassaman, David Berger
Abstract: This invention concerns pathological angiogenesis and cancer, related treatment methods, and related compositions. Also disclosed are related diagnosis kits and methods.
Abstract: Disclosed herein are a method and apparatus for filtering a reference pixel. A method of smoothing a reference pixel may include determining whether or not to perform smoothing on a reference pixel based on the size of a transform block and information about an intra-prediction mode for the transform block and determining a smoothing method by comparing the size of the transform block with the size of a maximum transform block. Accordingly, image coding efficiency can be increased, and picture quality can be improved.
Type:
Application
Filed:
August 5, 2019
Publication date:
November 21, 2019
Applicant:
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Inventors:
Byeung Woo JEON, Ho Young LEE, Kwang Hyun WON
Abstract: The present invention provides a health file access control system and method in an electronic medical cloud. The system comprises: a medical management center unit configured to generate a system public key and a system private key, and generate a private key for corresponding utilizer's attributes according to the system public key, the system private key, and a set of utilizer's attributes; an electronic medical cloud storage unit configured to receive and store a privacy-protected health file ciphertext; and at least one health file user access unit configured to encrypt the health file according to the system public key to obtain the privacy-protected health file ciphertext, and/or generate the set of utilizer's attribute, and decrypt the privacy-protected health file ciphertext according to the system public key and the private key for utilizer's attributes.
Type:
Application
Filed:
December 11, 2017
Publication date:
November 21, 2019
Applicant:
XI'AN UNIVERSITY OF POSTS AND TELECOMMUNICATIONS
Abstract: Embodiments of the invention provide a method of detecting one or more strains of Klebsiella pneumoniae. The method may include forming a plurality of mixtures for nucleic amplification. The method can include amplification of specific sequences within the K. pneumonia genome that can provide definitive information to distinguish between one or more types or strains of K. pneumonia.
Type:
Application
Filed:
February 22, 2019
Publication date:
November 21, 2019
Applicants:
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE, ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY
Inventors:
Jolene Bowers, Elizabeth Driebe, David Engelthaler, Paul Keim
Abstract: As monitoring systems for applications such as earthquake detection, oil and gas exploration, agriculture, and meteorological studies continue to advance in size and data quality, the task of data acquisition becomes equally challenging. Wireless systems for such monitoring applications are required to transfer data in a time-sensitive manner while conserving power in order to extend the operational life of the sensing/monitoring devices. Systems and methods for data acquisition for such scenarios are disclosed, with the objective of collision prevention and power conservation.
Type:
Application
Filed:
May 14, 2019
Publication date:
November 21, 2019
Applicants:
King Fahd University of Petroleum and Minerals, GEORGIA INSTITUTE OF TECHNOLOGY
Inventors:
Varun Amar REDDY, Gordon STUBER, Suhail AL-DHARRAB
Abstract: The present invention generally relates to plants comprising a CRISPR system or parts of a CRISPR system, compositions, containers, polynucleotide, vectors, delivery systems, parts of plants, methods for production, CRISPR systems, and components thereof. Further aspects of the invention include a method for identifying a CRISPR system which is functional in a plant cell and a method for improving a CRISPR system in a plant.
Type:
Application
Filed:
December 8, 2017
Publication date:
November 21, 2019
Applicants:
THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, REGENTS OF THE UNIVERSITY OF MINNESOTA, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Inventors:
Omar ABUDAYYEH, Joseph John BELANTO, Jonathan GOOTENBERG, Colby Garret STARKER, Daniel Francis VOYTAS, Feng ZHANG
Abstract: A medical device containing a sensor, a motor, one or more plates, and a control unit, for treating diabetes. The medical device vibrates the pancreas thereby improving blood and secretory hormone circulation and enhancing the production of insulin.
Abstract: Provided herein are methods for treating a bone-related disorder in a subject. At least one of a microtubule altering drug, for example, a microtubule disrupting drug or a microtubule stabilizing drug, a TRPV4 agonist or a NOX2 activator is administered to the subject. Also provided are related methods for treating a bone-related disorder in the subject, by further administering at least one of an anti-sclerostin agent, a parathyroid hormone agonist, a bisphosphonate, an estrogen mimic, or a selective estrogen receptor modulator is further administered to the subject with the at least one of a microtubule altering drug, a TRPV4 agonist or a NOX2 activator.
Type:
Application
Filed:
November 16, 2017
Publication date:
November 21, 2019
Applicant:
University of Baltimore, Maryland
Inventors:
Joseph Stains, Christopher Ward, James Lyons