Abstract: A ranking approach is used to determine rank-based relationships. In connection with various embodiments, the present invention is directed to a method for ranking nodes of a graph. A vector is provided as a function of a set of random parameters, and a probability matrix function is used, relative to nodes of the graph, to assess the statistics of the vector that solves a probability-based system. Certain embodiments are directed to determining a page rank for a web-based search.

Abstract: Systems and methods for detecting an image of an object using a multi-beam imaging system from an x-ray beam having a polychromatic energy distribution are disclosed. According to one aspect, a method can include generating a first X-ray beam having a polychromatic energy distribution. Further, the method can include positioning a plurality of monochromator crystals in a predetermined position to directly intercept the first X-ray beam such that a plurality of second X-ray beams having predetermined energy levels are produced. Further, an object can be positioned in the path of the second X-ray beams for transmission of the second X-ray beams through the object and emission from the object as transmitted X-ray beams. The transmitted X-ray beams can each be directed at an angle of incidence upon one or more crystal analyzers. Further, an image of the object can be detected from the beams diffracted from the analyzer crystals.

Abstract: A multi-stage parallel multi-character string matching device, including: a rule circuit having multiple rule units, each of the multiple rule units embodying a transition rule based on an AC-trie; a state circuit coupled with the rule circuit for determining multiple next-state data; and an output circuit coupled with the rule circuit for determining multiple matching output data.

Abstract: A pharmaceutical composition for inhibiting at least protein kinase in a cell of a subject includes a purine based triazole.

Abstract: The presently disclosed subject matter generally relates to methods and compositions for inhibiting the expression and/or activation of hypoxia-inducible factor 1 (HIF-1) genes in a hypoxic cell. More particularly, the methods disclosed herein relate to inhibition of HIF-1 activation in a cell, increasing sensitivity of a tumor cell to radiation and/or chemotherapy, delaying tumor growth, inhibiting tumor blood vessel growth, inhibiting inflammatory responses in a cell through the use of compositions that prevent the nitrosylation of HIF-1, and methods for screening for new inhibitors of HIF-1 activiation. Additionally, the compositions disclosed herein relate to compositions that can be employed in, and are identified by, the disclosed methods.

Abstract: The disclosure relates to novel C4 and C6 substituted androst-4-ene diones as well as andros-1,4-diene diones and derivatives thereof, their process of preparation, pharmaceutical compounds containing them, and the use of said compounds for the treatment of hormone-related disorders in mammals. This includes hormone-dependent cancers, particularly those caused by elevated levels of estrogen and its intermediates. These compounds can also be used in the treatment of other hormone-related disorders, including benign prostatic hyperplasia, cardiovascular disease, and neurodegenerative disorders.

Abstract: The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for managing CXCR4 related conditions, typically prevention or treatment of viral infections such as HIV or for managing cancer.

Abstract: The present invention provides electronic methods and apparatus for interactively authoring, sharing and analyzing digital video content. Methods for authoring include displaying visual data, defining each traversal as a time-based sequence of frames and annotating and storing a record of the traversal and its associated audio records. Defining the traversal Includes interactively panning the visual data by positioning an overlay window relative to the visual data and zooming in or out by resizing the overlay window. In alternative embodiments, the visual data may be displayed in a rectangular layout or a cylindrical layout. The methods are practiced using an integrated graphical interface, including an overview region displaying the visual data, a detail region displaying current data within the overlay window, and a worksheet region displaying a list of previously stored annotated traversal records.

Abstract: An apparatus for sensing strain or stress includes a body including magnetic shape-memory alloy (MSMA) material, having a first axis. A first drive coil and first sensor coil are wound around the body about the first axis. The drive coil is coupled to a power source and configured to generate an alternating magnetic field on the body. The first sensor coil is configured to detect changes in inductance of the body due to changes in magnetic permeability of the body with deformation thereof.

Abstract: A detection unit (10) detects a joint angle and a joint torque for causing the joint of a subject (1) to undergo passive flexion and extension movement, and an arithmetic unit (50) performs arithmetic processing on an output signal from the detection unit. The arithmetic unit divides the relationship between the joint torque and the joint angle in at least one of the extension phase and the flexion phase into two or more portions including a proximal-side portion and a distal-side portion according to a joint angle, and obtains the elastic coefficient of the joint from the relationship between the joint torque and the joint angle in at least one of the distal-side portion and the proximal-side portion. This enables distinguishing between a healthy subject and a Parkinson's disease patient with a simple configuration, without the measurement of surface myoelectric potential.

Abstract: In one aspect, the invention relates to substituted 6-methylnicotinamide analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present invention provides a novel cationized microfibrillated plant fiber and a method for manufacturing the same. A cationic microfibrillated plant fiber that is cationically modified with a quaternary-ammonium-group-containing compound, and that has an average diameter of 4 to 200 nm.

Abstract: This invention relates to novel pharmaceutical compositions comprising a therapeutically effective amount of a slow-release formulation of 5-hydroxytryptophan (5-HTP) and a serotonin-enhancing compound. The pharmaceutical compositions for use according to the invention are contemplated particularly useful for combating CNS disorders, including depressive disorders, bipolar disorders, anxiety disorders, obesity and pain.

Abstract: Novel heterocyclic materials are disclosed. The materials contain a fused tetracyclic structure that can improve the properties of OLED devices when the novel heterocyclic materials are incorporated into such devices.

Abstract: Environmental recognition systems may improve recognition accuracy by leveraging local and nonlocal features in a recognition target. A local decoder may be used to analyze local features, and a nonlocal decoder may be used to analyze nonlocal features. Local and nonlocal estimates may then be exchanged to improve the accuracy of the local and nonlocal decoders. Additional iterations of analysis and exchange may be performed until a predetermined threshold is reached. In some embodiments, the system may comprise extrinsic information extractors to prevent positive feedback loops from causing the system to adhere to erroneous previous decisions.

Abstract: A method for measuring sea waves includes: transmitting ultrasonic waves from an ultrasonic transmitter 2 provided on a buoy 1 into the sea, and receiving the ultrasonic waves from three transponders 3 on the seabed together with the time signals; detecting distances between the transponders 3 and the ultrasonic transmitter 2 based on the propagation time of the ultrasonic waves; high-pass filtering the distance data to extract a short-term fluctuation component; preparing and solving linear equations to determine the displacement in the height direction of the short-term fluctuation component and obtain a wave height.

Abstract: Messages are delivered in a mobile network by creating a communication route between a source node and a destination node comprised of virtual routers, each virtual router being fixed to a particular geographical area and including a plurality of mobile nodes, each of the mobile nodes being available to forward a data packet on behalf of a virtual router, and each mobile node upon receiving a data packet sent over the communication route monitoring for forwarding of the data packet by another mobile node and, if such forwarding is not detected, the mobile node forwarding the data packet.

Abstract: The present invention relates to a process for producing porous metallic materials comprising the steps of: (a) miming metallic particles with a carbonate additive and a binder, wherein the quantity of carbonate additive in the mixture is in the range of 40 to 90 vol % and compressing the mixture beyond the yield strength of the metallic particles; (b) heating the mixture to a first temperature sufficient to evaporate the binder; (c) heating and maintaining the temperature of the mixture to a second temperature sufficient to sinter the metallic particles but insufficient to decompose or melt the carbonate additive; (d) removing the carbonate additive from the sintered porous metallic material; and optionally (e) heating and maintaining the temperature of the porous metallic material to a third temperature greater than the second temperature so as to enhance the sintering. The present invention also relates to metallic materials produced by such a process.

Abstract: Compounds comprising a triphenylene moiety and a benzo- or dibenzo-moiety are provided. In particular, the benzo- or dibenzo-moiety has a fused substituent. These compounds may be used in organic light emitting devices, particularly in combination with yellow, orange and red emitters, to provide devices with improved properties.

Abstract: The present invention relates to magnetically coupleable robotic surgical devices. More specifically, the present invention relates to robotic surgical devices that can be inserted into a patient's body and can be positioned within the patient's body using an external magnet.