Abstract: This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.
Type:
Application
Filed:
September 3, 2013
Publication date:
March 27, 2014
Applicant:
The Regents of the University of California
Abstract: A series of novel phosphorus-containing compounds having the following formula is provided: in which: R1-R4, A, Q and m are as defined in the specification. A process for the preparation of the compound of formula (I) is also provided. A polymer of formula (PA), and preparation process and use thereof are further provided. A polymer of formula (PI), and preparation process and use thereof are also provided.
Type:
Application
Filed:
October 31, 2013
Publication date:
March 27, 2014
Applicants:
National Chung Hsing University, Chang Chun Plastics Co., Ltd.
Inventors:
Ching-Hsuan LIN, Tsung Li Lin, Yu-Ting Fang, Kuen-Yuan Hwang, An-Pang Tu
Abstract: The invention provides methods for reducing growth and/or metastasis of androgen-independent (castration resistant) prostate cancer in a tissue in an animal. In one embodiment the method comprises administering to the animal a therapeutically effective amount of a compound that reduces the number of B cells, and/or the function of B cells, in the tissue. In yet another embodiment, the invention provides methods for reducing androgen-induced growth of prostate epithelial cells in prostate tissue in an animal. In one embodiment, the method comprises administering to the animal a therapeutically effective amount of a compound that reduces the number of B cells, and/or the function of B cells, in the tissue.
Type:
Application
Filed:
January 31, 2012
Publication date:
March 27, 2014
Applicant:
The Regents of the University of California
Inventors:
Michael Karin, Massimo Ammirante, Ali Kuraishy
Abstract: Methods and compositions for reducing expression of a mutant huntingtin (mHTT) protein in a cell are provided. Such methods include contacting the cell with an effective amount of a nucleic acid silencing agent targeting a differentiating polymorphism in RNA encoding the mHTT.
Type:
Grant
Filed:
May 8, 2009
Date of Patent:
March 25, 2014
Assignee:
The University of British Columbia
Inventors:
Michael Hayden, Jeffrey Carroll, Simon Warby
Abstract: The present application relates to a high precision method for calibrating and removing distortion from a lens, and more particularly, a method for calibrating and removing distortion by arranging sensor readings to compensate for its presence and simultaneously optimize the resulting image magnification for best image quality.
Abstract: Methods are provided for uniform deposition of particles on curved surfaces such as fibers and coatings formed by the particles. Particles in the size range of 10-2000 nm are deposited onto a fibrous material via electrostatic interaction between charge modified fiber material surfaces and oppositely charged particles or metal ions. Various nonmetallic, bimetallic or other charged particles are deposited onto a fibrous material via electrostatic interaction between charged modified fibrous material surfaces and oppositely charged particles. Particles can be directly assembled onto a surface of a fibrous material by controlling hydrogen bonding interactions between interfaces of fibers and functionalized particles. Metal particles can also be deposited by in situ synthesis. A method is also provided for layer-by-layer deposition of particles over a fibrous material.
Abstract: Compositions and methods for protection against bacterial contamination are disclosed Antibacterial proteins and methods of use thereof are also disclosed.
Type:
Grant
Filed:
November 23, 2009
Date of Patent:
March 25, 2014
Assignee:
Southern Illinois University Edwardsville
Abstract: A method for creating a highly accurate nanostructure is provided, the method includes: (i) creating a highly accurate nanostructure prototype, wherein the highly accurate nanostructure prototype, when illuminated with a predefined illumination, provides a unique optical pattern; (ii) creating at least one highly accurate nanostructure mold from the highly accurate nanostructure prototype, wherein each highly accurate nanostructure mold enables a creation of a highly accurate nanostructure that is substantially similar to the highly accurate nanostructure prototype and which, when illuminated with the predefined illumination, provides the unique optical pattern; and (iii) molding the highly accurate nanostructure using the highly accurate nanostructure mold, wherein the highly accurate nanostructure, when illuminated with the predefined illumination, provides the unique optical pattern.
Abstract: The present invention relates to methods for the treatment of a disease or condition associated with lipid imbalance, comprising (a) decreasing arachidonic acid (AA) levels, (b) increasing docosahexaenoic acid (DHA) levels, (c) increasing DHA/AA ratio or (d) any combination of (a)-(c) in a subject using fenretinide. The invention also relates to diagnostic and screening methods based on the determination of lipid levels.
Type:
Grant
Filed:
December 13, 2006
Date of Patent:
March 25, 2014
Assignee:
The Royal Institution for the Advancement of Learning/McGill University
Inventors:
Danuta Radzioch, Claudine Guilbault, Juan Bautista De Sanctis
Abstract: A method of concentrating nanoparticles, having the steps of: adding and mixing an extraction solvent with a nanoparticles-dispersion liquid that nanoparticles are dispersed in a dispersion solvent, thereby concentrating and extracting the nanoparticles into a phase of the extraction solvent, and removing the dispersion solvent by filter-filtrating a liquid of concentrated extract, in which the extraction solvent is substantially incompatible with the dispersion solvent, and the extract solvent can form an interface after the extraction solvent is mixed with the dispersion solvent and left the mixture still; further a method of deaggregating aggregated nanoparticles, having the steps of: applying two or more ultrasonic waves different in frequency to a liquid containing aggregated nanoparticles, and thereby fining and dispersing the aggregated nanoparticles.
Type:
Grant
Filed:
May 8, 2006
Date of Patent:
March 25, 2014
Assignees:
FUJIFILM Corporation, Tohoku University
Abstract: A method for fabricating interconnecting lines inside via holes of a semiconductor device comprises steps of providing a template having a receiving trench and a connection surface both on the same side of the template; filling an electric-conduction material into the receiving trench; connecting a substrate having at least one via hole with the connection surface to interconnect the via hole with the receiving trench; heating the electric-conduction material to a working temperature to liquefy a portion of the electric-conduction material and make it flows from the receiving trench into the via hole; and cooling the electric-conduction material to form an interconnecting line inside the via hole. The present invention fabricates interconnecting lines by a heat-forming method, which features simple steps and has advantages of shorter fabrication time, lower fabrication complexity, higher fabrication efficiency, higher yield and lower fabrication cost.
Type:
Grant
Filed:
March 9, 2012
Date of Patent:
March 25, 2014
Assignee:
National Tsing Hua University
Inventors:
Wei-leun Fang, Chia Han Lin, Feng Yu Lee
Abstract: A system and method for leveraging physiological traits to control microprocessor frequency are disclosed. In some embodiments, the system and method may optimize, for example, a particular processor-based architecture based on, for example, end user satisfaction. In some embodiments, the system and method may determine, for example, whether their users are satisfied to provide higher efficiency, improved reliability, reduced power consumption, increased security, and a better user experience. The system and method may use, for example, biometric input devices to provide information about a user's physiological traits to a computer system. Biometric input devices may include, for example, one or more of the following: an eye tracker, a galvanic skin response sensor, and/or a force sensor.
Type:
Grant
Filed:
June 9, 2010
Date of Patent:
March 25, 2014
Assignee:
Northwestern University
Inventors:
Alex Shye, Yan Pan, Benjamin Scholbrock, J. Scott Miller, Gokhan Memik, Peter A. Dinda, Robert P. Dick
Abstract: A haptic actuator using a cellulose electro-active paper film is provided. The haptic actuator includes a cellulose electro-active paper film exhibiting a piezoelectric phenomenon and a metal electrode for applying electricity to the electro-active paper film, so that the haptic actuator can be provided in the form of a thin film, can manifest high transparency, and can produce displacement to the magnitude of sufficiently stimulating the sensor receptors of a user's skin in response to the applied electricity. Also, the haptic actuator is friendly to the environment and humans thanks to the use of cellulose which is an environmentally friendly material.
Type:
Grant
Filed:
November 14, 2011
Date of Patent:
March 25, 2014
Assignee:
Industry Collaboration Foundation of Korea University of Technology and Education
Abstract: Disclosed is a method of providing photocatalytic activity. Nanoparticulate matter comprising a strontium titanate ferrite of the general formula SrTi1-xFexO3- is provided, in which x is any value from 0 to 1. The nanoparticulate matter is exposed to electromagnetic radiation of a wavelength from about 380 nm to about 800 nm.
Abstract: A spectral interferometry apparatus and method are disclosed, that can be used to monitor or measure an unknown length by following a characteristic of an indicating signal. The measurement is performed by adjusting an optical path difference (OPD) in an interferometer part of an interferometer configuration until sound or light or both are obtained with the desired strength and pitch. Embodiments are presented where the unknown length is the eye length. Spectral interrogation of the interferometer optical output is achieved by reading the signal of an analogue photodetector array in a spectrometer or by tuning a swept source and processing the signal of a photodetector. Sound of different pitches are produced either directly in this process, or by using a nonlinear amplifier, or a mixer. For enhanced signal, the array may be driven by a nonlinear clock or the swept source may be driven by a distorted driving signal.
Abstract: The present invention relates to a method for manufacturing silicon thin-film solar cells, including: providing a substrate; forming a first electrode on the substrate; forming a first doped semiconductor layer on the first electrode by chemical vapor deposition; forming an intrinsic layer on the first doped semiconductor layer by chemical vapor deposition, where the intrinsic layer includes a plurality of amorphous/nanocrystalline silicon layers, and the intrinsic layer has various energy bandgaps formed by varying average grain sizes of the amorphous/nanocrystalline silicon layers; forming a second doped semiconductor layer on the intrinsic layer by chemical vapor deposition, where one of the first doped semiconductor layer and the second doped semiconductor layer is a p-type amorphous silicon layer and the other is an n-type amorphous/nano-microcrystalline silicon layer; and forming a second electrode on the second doped semiconductor layer.
Type:
Grant
Filed:
January 4, 2012
Date of Patent:
March 25, 2014
Assignee:
National Central University
Inventors:
Tomi T. Li, Jeng-Yang Chang, Sheng-Hui Chen, Cheng-Chung Lee
Abstract: A method of extracting data from an identifiable monochromatic pattern. The method comprises separating a polychromatic optical signal, received from an object having identifiable monochromatic pattern, into a plurality of wavelength components, separately capturing each of the wavelength components, reconstructing a plurality of images each from a different wavelength component, detecting the identifiable monochromatic pattern in one or more of the images, and extracting data associated with or encoded by the detected identifiable monochromatic pattern. The images have different depths of field.
Type:
Grant
Filed:
March 10, 2011
Date of Patent:
March 25, 2014
Assignee:
Ramot at Tel-Aviv University Ltd.
Inventors:
Benjamin Milgrom, Emanuel Marom, Naim Konforti, Michael Golub
Abstract: IVIG replacement compounds are derived from recombinant and/or biochemical creation of immunologically active biomimetic(s). These replacement compounds are then screened in vitro to assess each replacements compound's efficiency at modulating immune function. Particular replacement compounds are selected for further in vivo validation and dosage/administration optimization. Finally, the replacement compounds are used to treat a wide range of diseases, including inflammatory and autoimmune diseases.
Type:
Grant
Filed:
May 30, 2008
Date of Patent:
March 25, 2014
Assignees:
Gliknik Inc., University of Maryland, Baltimore
Inventors:
Scott E. Strome, Dan H. Schulze, David S. Block, Henrik Olsen
Abstract: The present invention relates to methods of making articles, and systems for providing wool article have self-cleaning properties. The self-cleaning properties are brought about coating the wool articles with a photocatalyst formulation. The formulation contains titanium compounds, stabilizers, catalysts, and water.
Type:
Grant
Filed:
April 2, 2007
Date of Patent:
March 25, 2014
Assignees:
The Hong Kong Polytechnic University, Australian Wool Inovation Limited
Inventors:
Walid Abdelhamid Daoud, Sze Kar Leung, Wing Sze Tung, Hao Zhong John Xin, Ka Leung Kevin Cheuk, Xiaowen Wang, Yee Yee Kong, Kaihong Qi