Abstract: A method of simulating, reconstructing and scaling digital data sets, in particular images, but not exclusively. The method of the invention is based on a training image that is directly sampled each time a point in the simulation image is to be filled, and does not need the preliminary creation of a data structure storing conditional probabilities, as it is often the case in known multipoint simulation method. Accordingly, the method of the invention is less memory-demanding than conventional methods, and is better suited to simulations including continuous variables. Embodiments regarding the application to reconstruction of partial images and downscaling are also presented.

Abstract: Disclosed herein are methods and devices of obtaining plethysmograph readings and utilizing plethysomography to identify when pilots are about to experience GLOC. Furthermore, in other embodiments, the invention pertains to methods and devices designed to warn a pilot that he/she is about to enter GLOC and/or automatically averting catastrophic damage or injuries by directing a plane being piloted to take predetermined corrective actions. Specifically disclosed is a system embodiment for assisting in the prevention of gravity induced loss of consciousness.

Abstract: Disclosed herein are methods for improving fruit production or fruit quality in fruit trees, such as decreasing cold damage, increasing fruit size, increasing fruit quality, and/or increasing fruit set. In some embodiments, the disclosed methods include methods of decreasing cold damage to a fruit tree including applying an effective amount of a composition including DL-?-aminobutyric acid to the fruit tree, thereby decreasing cold damage, for example as compared to a control. In other embodiments, the disclosed methods include methods of increasing fruit size or fruit quality of fruit from a fruit tree, including applying an effective amount of a composition including prohexadione-calcium to the fruit tree after anthesis, thereby increasing fruit size or fruit quality, for example as compared to a control.

Abstract: A CPT1 inhibitor compound is represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof: or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating a subject having cancer comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.

Abstract: The combination of compounds of the hydroxytolan family with ascorbate plus naphthoquinone (Vitamin K3; VK3), or a quinone or semiquinone analogue of VK3, kill tumor cells, inhibit tumor growth and development, and treat cancer in subjects in need thereof.

Abstract: The present invention provides methods for making improved zeolite and crystalline silicoaluminophosphate (SAPO) membranes, in particular SAPO-34 membranes, on a porous support through improved removal of the organic structure-directing templating agent. A calcining step is performed in an oxygen free atmosphere, such as under a vacuum or inert gas, to remove the organic templating agent. By removing the templating agent in the absence of oxygen, the calcination step can remove a greater amount of the templating agent than comparable template removal steps conducted in the presence of oxygen and the calcination step can be conducted at significantly lower temperatures. The membranes of the present invention provide increased permeance while maintaining comparable selectivity for gas separations, particularly carbon dioxide (CO2) and methane (CH4) separations and separations at high temperatures.

Abstract: The present invention provides for increasing fluorescence detection in surface assay systems while increasing kinetics of a bioreaction therein by providing low-power microwaves to irradiate metallic materials within the system in an amount sufficient to increase heat thereby affecting the kinetics of a bioreaction therein.

Abstract: A microwave harmonic processing circuit includes (n?1) parallel open ended stubs differing in length, connected in parallel to an output terminal of a serial transmission line at a single point, and having predetermined electrical lengths corresponding to second to higher n-th (n is any integer) harmonics, respectively, the serial transmission line having an input terminal connected to an output terminal of a transistor and having a predetermined electrical length; a first strip conductor connecting the serial transmission line to two parallel open ended stubs of the (n?1) parallel open ended stubs at a single connecting point; a second strip conductor connecting the (n?3) parallel open ended stubs to each other at a single connecting point; a ground layer disposed between first strip conductor and second strip conductor; and a via electrically connecting a connecting portion of first strip conductor and a connecting portion of second strip conductor.

Abstract: Aphis glycines resistance (RAG) genes are provided by this invention, along with methods for identifying their presence using marker-assisted selection. Varieties of G. max and G. soja having resistance to A. glycines have been identified. The RAG genes, as well as the methods, aphid-resistant varieties, and markers disclosed herein may be used to breed new elite lines expressing soybean aphid resistance.

Abstract: Novel, activatable dyes, such as photoactivatable dyes, e.g., oxazine dyes, are described. Some of the dyes are targeting dyes that can, e.g., target biomolecules, such as polypeptides, proteins, or nucleic acids. Upon activation, such as by irradiation, the novel dyes rapidly turn on their fluorescence and emit light, such as near-IR light with spatial and temporal precision.

Abstract: Exocyclic peptide mimetics that disable Fas were developed. A three dimensional model of the Fas receptor-ligand complex was constructed and structurally predicted regions of the receptor that were relevant to binding ligand were used to create constrained peptide mimetics. Exocyclic anti-Fas peptide mimetics were identified that block Fas receptor-ligand interactions, and modulate Fas biological activity both in vitro and in vivo. The mimetics are useful, e.g., for treating Fas-related pathologies.

Abstract: A method of preparing a cold adapted xylanase by use of recombinant DNA techniques. A nucleic acid and corresponding amino acid sequences of a cold adapted xylanase, isolated from antarctic marine origin, preferably from an Antarctic bacteria (Psychrobacter sp.) are provided. These can be used in a variety of industrial contexts and for a variety of commercial purposes including more complete hydrolysis of lignocellulosic biomass into simple sugars that can then be fermented to products, such as liquid fuels and chemical feedstocks. The enzymes are also useful in the production methods of other industries, such as the animal feed, baking, and paper industries.

Abstract: An isolated nucleic acid molecule comprising, or consisting of, a polynucleotide sequence encoding an oligopeptide capable of inducing post-mating depression of receptivity to mating in female insects, wherein said oligopeptide is resistant to proteolytic degradation, is provided for expression in sterile transgenic male insects useful in the control of insect populations.

Abstract: An arthroplasty device is provided having an interpenetrating polymer network (IPN) hydrogel that is strain-hardened by swelling and adapted to be held in place in a joint by conforming to a bone geometry. The strain-hardened IPN hydrogel is based on two different networks: (1) a non-silicone network of preformed hydrophilic non-ionic telechelic macromonomers chemically cross-linked by polymerization of its end-groups, and (2) a non-silicone network of ionizable monomers. The second network was polymerized and chemically cross-linked in the presence of the first network and has formed physical cross-links with the first network. Within the IPN, the degree of chemical cross-linking in the second network is less than in the first network. An aqueous salt solution (neutral pH) is used to ionize and swell the second network. The swelling of the second network is constrained by the first network resulting in an increase in effective physical cross-links within the IPN.

Abstract: Disclosed are a method for demodulating received signals and an apparatus therefore which can maintain quality of signals and can reduce computational complexity. A demodulation method of a receiving device for receiving a plurality of signals modulated through a M-ary (M is a natural number of 1 or more) modulation method includes: comparing channel frequency response power of a first channel with channel frequency response power of a second channel, selecting M reference signals on the basis of the compared result, selecting corresponding signals paired with respective selected M reference signals, and estimating transmitting signals from the M signal pairs including pairs of the reference signal and the corresponding signal. Accordingly, the computational complexity is reduced from O (M2) to O (M).

Abstract: The present invention relates to a biomarker associated with a cancer and a method using the biomarker to evaluate a risk of proliferation, invasion, or metastasis of a cancer. The method of the present invention comprises the following steps: (A) providing a tissue sample to evaluate for risk of proliferation, invasion, or metastasis of a cancer, wherein the tissue sample comprises a non-cancer region, and a suspected cancer region; (B) detecting expression levels of a biomarker and a predetermined standard in the non-cancer region and the suspected cancer region respectively, wherein the biomarker is T-cell lymphoma invasion and metastasis 2 (TIAM2); (C) comparing the expression levels of the biomarker and the predetermined standard in the non-cancer region to the expression levels of the biomarker and the predetermined standard in the suspected cancer region.

Abstract: Prochelator compounds of Formula (I) or Formula (II) are described, along with methods of using the same and pharmaceutical formulations or compositions containing the same.

Abstract: A compound having inhibitory activity on the binding of a substance ? to a PTGS suppressor protein, wherein the substance ? has a property of inducing PTGS and a property of binding to the PTGS suppressor protein and shows a decrease in the property of inducing PTGS upon binding to the PTGS suppressor protein.

Abstract: A method and system of generating a super-resolution image is provided. fusing The method includes inputting an image; and generating an estimated high-resolution image of a current time by fusing an input image and an estimated high-resolution image of a previous time corresponding to the input image.

Abstract: The invention provides methods and compositions for reducing or inhibiting bone resorption, osteoclast differentiation and stimulation and the loosening of medical prostheses by administering a compound or agent that modulates an adenosine receptor such as the adenosine A2A receptor, in particular, an agonist of an adenosine A2A receptor. The invention also extends to pharmaceutical compositions comprising such an agent that modulates an adenosine receptor such as an adenosine A2A agonist and to prosthetic devices containing such an agent that modulates an adenosine receptor such as an A2A agonist on one or more surfaces or within the prosthetic device such as, for example, suspended in the cement forming the prosthetic device.