Patents Assigned to University
  • Patent number: 8207329
    Abstract: The present invention provides compounds of the general Formula DI: along with methods of making such compounds, formulations containing the same, and methods of using the same (e.g., in photodynamic therapy, for the production of solar cells, etc.).
    Type: Grant
    Filed: November 30, 2006
    Date of Patent: June 26, 2012
    Assignee: North Carolina State University
    Inventors: Jonathan S. Lindsey, Joydev K. Laha, Muthiah Chinnasamy, K. Eszter Borbas
  • Patent number: 8206722
    Abstract: The present disclosure provides methods and uses for controlling tight blood glucose levels in a subject comprising administering an effective amount of a somatostatin inhibitor. The present disclosure provides methods and uses for treating or preventing hypoglycemia in a subject comprising administering an effective amount of a somatostatin inhibitor.
    Type: Grant
    Filed: November 9, 2010
    Date of Patent: June 26, 2012
    Assignee: The Governing Council of the University of Toronto
    Inventors: Mladen Vranic, Jessica Yue, Suad Efendic
  • Patent number: 8206206
    Abstract: A gaming machine which determines establishment/non-establishment of a shift condition for shifting a game mode from a normal game mode to a special game mode, shifts to the special game mode based on the determination result, and allows an instruction of A player to be inputted thereto, extracts predetermined number of card data to be used in the special game mode, selects a first and a second card data on the gaming machine side and a player side from among the extracted card data, and determines right/wrong of a designating instruction according to a result of comparison between the card data. Upon win, this gaming machine determines establishment/non-establishment of a winning combination based on the extracted card data, and when a winning combination is established, the machine performs payout corresponding to the established combination.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: June 26, 2012
    Assignee: Universal Entertainment Corporation
    Inventor: Hiroaki Kashima
  • Patent number: 8208504
    Abstract: A laser system using ultrashort laser pulses is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present invention employs a femtosecond laser and a spectrometer. Still another aspect of the present invention uses a laser beam pulse, a pulse shaper and a SHG crystal. In yet another aspect of the present invention, a multiphoton intrapulse interference phase scan system and method characterize the spectral phase of femtosecond laser pulses. Fiber optic communication systems, photodynamic therapy and pulse characterization tests use the laser system with additional aspects of the present invention.
    Type: Grant
    Filed: November 4, 2008
    Date of Patent: June 26, 2012
    Assignee: Board of Trustees Operation Michigan State University
    Inventors: Marcos Dantus, Vadim V. Lozovoy
  • Patent number: 8207228
    Abstract: A class of topomimetic calixarene-based peptide mimetics is described. Calixarene-based peptide mimetics have various biological activities such as, for example, bactericidal activity, antiangiogenic activity, and/or antitumor activity. Methods of use and methods of designing calixarene-based peptide mimetics are described.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: June 26, 2012
    Assignee: Regents of the University of Minnesota
    Inventors: Kevin H. Mayo, Thomas R. Hoye, Xuemei Cheri
  • Patent number: 8208723
    Abstract: Provided is a smoke detecting apparatus capable of detecting occurrence of smoke at high sensitivity while suppressing an effect of disturbance. The smoke detecting apparatus for detecting occurrence of smoke by subjecting an image captured by a monitoring camera to image processing includes: an image memory (10) for storing a plurality of images captured by the monitoring camera in a time series; and a smoke detection area selecting portion (20) for calculating a luminance histogram of the same pixel for each predetermined pixel a plurality of times in a past predetermined period based on the plurality of images stored in the image memory (10), detecting presence or absence of a luminance value that has been newly generated due to occurrence of one of an intrusive object and smoke based on the luminance histogram, and identifying candidate regions to be subjected to the image processing.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: June 26, 2012
    Assignees: Nohmi Bosai Ltd., The University of Tokushima
    Inventors: Takatoshi Yamagishi, Kazuhisa Nakano, Kenji Terada
  • Patent number: 8206332
    Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: June 26, 2012
    Assignees: Zoll Circulation Inc., The Regents of the University of California
    Inventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worthen, Yves Pierre Gobin
  • Patent number: 8207081
    Abstract: A novel M—Pd—Cr2O3 (M?Pt, Ru, Rh, Os, Au and Ag) nanocomposite cocatalysts and its preparation method. The cocatalysts loaded on CdS photocatalyst enhances the photocatalytic activities toward H2 evolution from aqueous solutions (NH4)2SO3, a regenerable electron donor, under sunlight radiation. An embodiment provides a new and facile method and system for the preparation of M—Pd—Cr2O3 nanocomposite cocatalysts at room temperature. Pd—Cr2O3 loaded CdS photocatalyst has higher hydrogen evolution activity than that of a plain Pd metal loaded CdS and its performance is comparable to that of Pt/CdS photocatalyst. Formation of a Pd—Cr2O3 composite with reduced size of nanoparticles results in an increase in the photocatalyst activity for H2 evolution.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: June 26, 2012
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Cunping Huang, Weifeng Yao, Nazim Muradov, Ali Raissi
  • Patent number: 8206594
    Abstract: A novel system and method for fluid management for accurate continuous venovenous hemofiltration (CWH) in extracorporeal membrane oxygenation (ECMO). The fluid management or CWH system is automated and configured for operation as a stand alone unit and can be easily integrated with an ECMO system. The fluid management system is capable of producing either perfect or negative fluid balance between ultrafiltrate removal and replacement fluid delivery. The fluid management system can achieve electrolyte replacement over a range of flow rates needed to care for patients ranging from neonates to adults. Finally, the novel fluid management system preserves patient safety, maintains sterility during operation, is easy to operate, and is compact enough to fit near a patient's bed.
    Type: Grant
    Filed: June 6, 2008
    Date of Patent: June 26, 2012
    Assignees: Emoery University, Children's Healthcare of Atlanta, Georgia Tech Research Corporation
    Inventors: James D. Fortenberry, Ajit P. Yoganathan, Philippe Sucosky, Lakshmi Prasad Dasi, Matthew L. Paden
  • Patent number: 8206638
    Abstract: Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The barrier rapidly hardens forming a solid barrier when triggered by a suitable energy source.
    Type: Grant
    Filed: January 21, 2010
    Date of Patent: June 26, 2012
    Assignee: The Regents of the University of California
    Inventor: Jane Emerson
  • Patent number: 8206593
    Abstract: New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.
    Type: Grant
    Filed: December 5, 2005
    Date of Patent: June 26, 2012
    Assignees: Fluidigm Corporation, California Institute of Technology, The Regents of the University of California, Siemens Medical Solutions USA, Inc.
    Inventors: Chung-cheng Lee, Guodong Sui, Arkadij Elizarov, Hartmuth C. Kolb, Jiang Huang, James R. Heath, Michael E. Phelps, Stephen R. Quake, Hsian-rong Tseng, Paul Wyatt, Antoine Daridon
  • Patent number: 8207357
    Abstract: An antitumor agent which is not easily excreted from tumor cells and is suitable for a topical treatment. Specifically disclosed is a rotaxane compound with contains a compound represented by chemical formula 1 as the base structure. (In chemical formula 1, m?2, n?3, and X represents an anionic molecule or an anionic atom.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: June 26, 2012
    Assignees: Wan Station Co., Ltd., Tokyo Institute of Technology, Fukuoka University, Kinki University
    Inventors: Toshikazu Takata, Yasuhito Koyama, Kazuko Nakazono, Toshihide Hasegawa, Young-Gi Lee, Nobufumi Ono, Kazuto Nishio, Yoshihiko Fujita
  • Patent number: 8207735
    Abstract: A method and apparatus for tuning the frequency and matching the impedance of an RF coil, or probe, used for nuclear magnetic resonance (NMR)/magnetic resonance imaging (MRI) are provided. In NMR/MRI, the RF coils used to acquire the data are tuned and impedance matched for enhanced performance. An embodiment of the subject invention allows for enhanced frequency and impedance adjustments to be made remotely when, for example, space for accessing the mechanical matching components is limited or not available. Applications in which embodiments of the invention can be beneficial include, but are not limited to, medical systems, very high field research magnets and research or commercial MRI/NMR systems.
    Type: Grant
    Filed: January 10, 2008
    Date of Patent: June 26, 2012
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Melvin Daniel Clark, John Robert Forder
  • Patent number: 8207142
    Abstract: Zebularine has hypomethylating activity, and can be used to inhibit, reverse, and/or reduce DNA methylation in vivo and in vitro. Methods are provided for treating methylation-linked conditions through the application of 2-pyrimidinone derivatives, such as Zebularine. Compositions, including pharmaceutical compositions, comprising such derivatives are also provided. Also provided are kits for use in inhibiting DNA methylation, which kits include an amount of a 2-pyrimidinone derivative.
    Type: Grant
    Filed: July 30, 2002
    Date of Patent: June 26, 2012
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, University of Oregon, University of Miami School of Medicine, University of Sounthern California, University of Miami
    Inventors: Eric U. Selker, Cindy B. Matsen, Peter A. Jones, Jonathan Cheng, Sheldon B. Greer, Victor E. Marquez
  • Patent number: 8206968
    Abstract: The present invention provides a mutant 27 kDa NIa proteinase having reduced self-cleavage activity relative to the self-cleavage activity of its wild-type proteinase. The mutant has the same substrate cleavage activity as the wild-type proteinase but is more stable than the wild-type proteinase. The present invention also provides a method of obtaining large quantities of active 27 kDa NIa proteinase for use as a tool for purification of other proteins.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: June 26, 2012
    Assignee: Yale University
    Inventors: Jennifer A. Doudna, Louise J. Lucast, Robert T. Batey
  • Patent number: 8207098
    Abstract: A lubricant additive comprising a rod-like liquid crystal compound possessing a cation group and an anion is disclosed. The rod-like liquid crystal compound is typically a specific type of 4-(1,3-diox-2-yl)pyridinium salt and exhibits an effect of reducing the coefficient of friction if added in a small amount. A lubricant composition and a grease composition comprising the lubricant additive are also disclosed.
    Type: Grant
    Filed: September 10, 2007
    Date of Patent: June 26, 2012
    Assignees: Yamanashi University, Balbis Co., Ltd., Nippon Chemical Industrial Co., Ltd.
    Inventor: Yuichiro Haramoto
  • Patent number: 8206640
    Abstract: A process and apparatus for collecting continuous fibers or filaments as a uniform batt comprises a filament emitter in the form of a spinning die, a venturi, a diffuser, and a fiber collection bed. The filaments move downward after being created by the emitter, and exhaust ports create in the diffuser an airflow having a direction against the flow of the filaments so that the filaments are decelerated before contacting the fiber collection bed.
    Type: Grant
    Filed: July 26, 2004
    Date of Patent: June 26, 2012
    Assignee: The University of Tennessee Research Foundation
    Inventors: Ahmad D. Vakili, Daniel F. Rossillon
  • Patent number: 8206700
    Abstract: The disclosure provides an antigenic composition useful for immunization against tularemia. The disclosure provides a method for producing a vaccine for preventing tularemia in humans and animals, a new vaccine against tularemia in humans and animals, and a new approach to producing vaccines against tularemia.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: June 26, 2012
    Assignee: The Regents of the University of California
    Inventors: Marcus A. Horwitz, Qingmei Jia, Bai-Yu L. Clemens, Daniel Clemens
  • Patent number: 8206724
    Abstract: The instant invention relates to antigens and nucleic acids encoding such antigens obtainable by screening a Chlamydia genome. In more specific aspects, the invention relates to methods of isolating such antigens and nucleic acids and to methods of using such isolated antigens for producing immune responses. The ability of an antigen to produce an immune response may be employed in vaccination or antibody preparation techniques.
    Type: Grant
    Filed: April 19, 2007
    Date of Patent: June 26, 2012
    Assignees: Auburn University, Board of Regents, The University of Texas System
    Inventors: Stephen A. Johnston, Katherine Stemke-Hale, Kathryn F. Sykes, Bernhard Kaltenboeck
  • Patent number: 8206843
    Abstract: Disclosed are a gradient bioceramic coating comprising a rare earth oxide, a broadband laser method for preparing the bioceramic coating, and the use of the bioceramic coating in the field of medical materials.
    Type: Grant
    Filed: October 16, 2008
    Date of Patent: June 26, 2012
    Assignee: Guizhou University
    Inventors: Qibin Liu, Wenfei Li, Ling Wu