Abstract: An automatic brightness adjusting method and apparatus for image signal processor (ISP) is provided. The image processing apparatus may include a histogram generating unit, a cumulative distribution function calculator, and a histogram equalization (HE) unit. The histogram generating unit may generate a histogram of brightness values of pixels in an input image. The cumulative distribution function calculator may generate a cumulative distribution function and an inverse cumulative distribution function, based on the generated histogram. The HE unit may generate a conversion function based on the cumulative distribution function and the inverse cumulative distribution function, and may apply HE to the input image based on the conversion function so as to generate an output image.
Type:
Application
Filed:
October 14, 2011
Publication date:
June 7, 2012
Applicants:
Soongsil University Research Consortium techno-PARK, Electronics and Telecommunications Research Institute
Inventors:
Seong Hoon Choi, Jang Hyun Park, Chang Sun Kim, Seong Soo Lee, Jung Hwan Choi
Abstract: The present invention provides a method for inducing differentiation of pluripotent stem cells into neural precursor cells, comprising culturing the pluripotent stem cells in the presence of a small molecule BMP inhibitor, and induced neural precursor cells prepared by this method.
Abstract: An apparatus for transferring cryogenic refrigeration includes a cryocooler interface, a housing, a working fluid, a heat exchanger, a flexible thermal link, and a remote cartridge cold head. The cryocooler interface is thermally connected to a cryocooler providing a source of refrigeration. The refrigeration is passed from the crycooler into the heat exchanger via the cryocooler interface. The remote cartridge cold head is attached to a remote location. Heat is drawn from the remote location through the remote cartridge cold head and into the heat exchanger via the working fluid within the flexible thermal link and housing. Within the heat exchanger, heat is transferred from the working fluid to the refrigeration source, such as a cryocooler; accordingly, the remote location is cooled.
Type:
Application
Filed:
December 12, 2011
Publication date:
June 7, 2012
Applicants:
Korea Basic Science Institute, The Florida State University Research Foundation, Inc.
Inventors:
Thomas Andrew Painter, Yeon Suk Choi, Dong Lak Kim, Hongyu Bai
Abstract: An energetic ionic liquid catalytic decomposition gas generator uses stoichiometric and nonstoiciometric mixtures of specific energetic ionic liquids and iridium catalyst. The catalyst temperature used and gas production versus ignition may be controlled by combining one or more cationic species with one or more anionic species of the ionic liquid(s).
Type:
Application
Filed:
December 1, 2010
Publication date:
June 7, 2012
Applicants:
The University of Alabama, Streamline Automation, LLC
Inventors:
Roberto DiSalvo, H. Waite H. Dykes, JR., Robin Rogers, Julia Shamshina, Marcin Smiglak
Abstract: The invention comprises compositions and methods for loading both magnetic resonance contrast agents and therapeutic agents into liposomes, such as low temperature sensitive liposomes (LTSLs). In certain embodiments, a passive technique is used to load the liposomes. In other embodiments, an active technique is used to load the liposomes. In further embodiments, a magnetic resonance contrast agent and Doxorubicin are loaded into the liposomes. The liposome compositions have higher contrast-agent loadings and are more stable, than those known in the art.
Type:
Application
Filed:
February 23, 2010
Publication date:
June 7, 2012
Applicant:
Duke University Office of Technology & Venture
Inventors:
Mark W. Dewhirst, Pavel Yarmolenko, Bradford J. Wood, Matthrew R. Dreher, Ayele H. Negussie
Abstract: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.
Type:
Application
Filed:
November 4, 2011
Publication date:
June 7, 2012
Applicant:
The Regents of the University of California
Inventors:
Charles S. Zuker, Jon E. Adler, Juergen Lindemeier
Abstract: A three-dimensional OFDN apparatus of the present invenstion comprises: a serial-parallel conversion unit for converting a serial input signal into N parallel input signals; a three-dimensional signal mapping unit for mapping the N parellel input signals on three-dimensional coordinates of a cube-in-cube type constellation, respectively; and a two-dimensional inverse Fourier transform unit for performing an inverse Fourier transform by generating a two-dimensional matrix on the basis of the mapped three-dimensional coordinates.
Type:
Application
Filed:
August 20, 2010
Publication date:
June 7, 2012
Applicants:
Industry-Academic Cooperation Foundation Gyeongsang National University, Electronics and Telecommunications Research Institute
Abstract: Embodiments of the present disclosure include double-fusion human embryonic stem cells, methods of imaging double-fusion human embryonic stem cells, double-fusion polynucleotides, double-fusion proteins, triple-fusion human embryonic stem cells, methods of imaging triple-fusion human embryonic stem cells, triple-fusion polynucleotides, triple-fusion proteins, methods of monitoring the progression of human embryonic stem cells, methods of making isolated double-fusion human embryonic stem cells, methods of making isolated triple-fusion human embryonic stem cells, and the like.
Type:
Application
Filed:
January 26, 2012
Publication date:
June 7, 2012
Applicant:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Joseph Ching-Ming Wu, Feng Cao, Sanjiv Sam Gambhir
Abstract: The invention relates to elastomeric, polymeric bone substitute compositions, methods for their preparation and their use in clinical applications, such as bone engineering and regeneration applications. The bone substitute compositions are osteoconductive in the absence of a biomolecule component. The bone substitute compositions are capable to regenerate bone in vitro or in vivo. The bone substitute compositions can be implanted into a bone defective site of a patient, and particularly, in the orthopedic, dental and caraniofacial areas of the patient.
Type:
Application
Filed:
December 2, 2011
Publication date:
June 7, 2012
Applicant:
University of Pittsburgh - Of The Commonwealth System Of Higher Education
Abstract: Systems and methods for detecting concurrency bugs are provided. In some embodiments, context-aware communication graphs that represent inter-thread communication are collected during test runs, and may be labeled according to whether the test run was correct or failed. Graph edges that are likely to be associated with failed behavior are determined, and probable reconstructions of failed behavior are constructed to assist in debugging. In some embodiments, software instrumentation is used to collect the communication graphs. In some embodiments, hardware configured to collect the communication graphs is provided.
Type:
Application
Filed:
December 6, 2011
Publication date:
June 7, 2012
Applicant:
University of Washington through its Center for Commercialization
Abstract: A lithium air battery including: a negative electrode including lithium; a positive electrode using oxygen as a positive active material; and an organic electrolyte, wherein the organic electrolyte includes a metal-ligand complex.
Type:
Application
Filed:
December 6, 2011
Publication date:
June 7, 2012
Applicants:
National University Corporation Mie, Samsung Electronics Co., Ltd.
Abstract: The complexity of regulations in healthcare, financial services, and other industries makes it difficult for enterprises to design and deploy effective compliance systems. The present invention supports compliance by using formalized portions of applicable laws to regulate business processes that use information systems. An embodiment of the present invention uses a stratified fragment of Prolog with limited use of negation to formalize a portion of the US Health Insurance Portability and Accountability Act (HIPAA). An embodiment of the invention provides for deployment in a prototypical hospital that implements a Web portal messaging system.
Type:
Application
Filed:
August 27, 2011
Publication date:
June 7, 2012
Applicant:
The Board of Trustees of the Leland Stanford, Junior, University
Inventors:
Sharada Sundaram, Peifung E. Lam, John C. Mitchell
Abstract: The present invention relates to copolymer compositions for alcohol-selective membranes and methods of selectively separating an alcohol such as ethanol from an aqueous solution using such membranes. The copolymer compositions may be block copolymers of polystyrene-polybutadiene-polystyrene (hereafter “SBS”) having cylindrical morphologies; graft diblock copolymers synthesized by ring-opening metathesis polymerization of two cycloalkene monomers, wherein at least one of the cycloalkene monomers is substituted with one or more polydialkylsiloxane groups; or triblock copolymers comprising a middle block comprising a polymerized cycloalkene monomer and two end groups. The synthesized graft and triblock copolymer compositions may have a spherical, lamellar, cylindrical, double diamond, or gyroid morphologies. The copolymer compositions may contain a structural block that imparts essential mechanical properties to the membrane (e.g., polystyrene) and may also contain an alcohol transporting block (e.g.
Type:
Application
Filed:
March 10, 2011
Publication date:
June 7, 2012
Applicant:
The Regents of the University of California
Inventors:
Nitash P. BALSARA, Ashish K. Jha, Liang Chen
Abstract: The present invention provides methods and compositions for the stimulation of immune responses. Specifically, the present invention provides methods and compositions for the use of nanoemulsion compounds as mucosal adjuvants to induce immunity against environmental pathogens. Accordingly, in some embodiments, the present invention provides nanoemulsion vaccines comprising a nanoemulsion and an inactivated pathogen or protein derived from the pathogen. The present invention thus provides improved vaccines against a variety of environmental and human-released pathogens.
Type:
Application
Filed:
October 30, 2007
Publication date:
June 7, 2012
Applicant:
The Regents of the University of Michigan
Inventors:
James R. Baker, Anna Bielinska, Andrzej Myc
Abstract: A method of fabricating an array of micro electrodes enabled to have customizable lengths. A substantially criss-cross pattern of channels on a top surface of the work-piece substrate (10) is formed using electrical discharge machining to form a plurality of shaped columns (20) having tapered profiles. The shaped columns have a tapering profile which extends at least 50% of the length of the columns. The plurality of shaped columns is etched to sharpen the tapered tips into needle tips forming the array of microelectrodes.
Abstract: Contour-mode piezoelectric devices and methods of forming contour mode piezoelectric devices. The contour mode piezoelectric device includes a piezoelectric film having first and second surfaces and suspended so that it is spaced away from a substrate. The contour mode piezoelectric device also includes first and second patterned electrodes respectively disposed on the first and second surfaces of the piezoelectric film, at least one of the first and second patterned electrodes having variable width along a length thereof.
Type:
Application
Filed:
April 9, 2010
Publication date:
June 7, 2012
Applicant:
The Trustees of the University of Pennsylvania
Abstract: This invention relates to nucleic acid aptamers that recognize and bind the complement protein C3 or its biologically active proteolytic products and methods of their use. Particularly preferred are bi-functional aptamer construct that binding specifically with C3b or iC3b, and another target protein. Use of these molecular constructs for commandeering the opsonization process is also described herein.
Type:
Application
Filed:
May 20, 2009
Publication date:
June 7, 2012
Applicant:
Research Foundation of State University of New York at Albany
Inventors:
Hua Shi, Albert J.T. Millis, Kimi Nishikawa, Prabhat Kumar Mallik
Abstract: A method processes segmented iris images obtained by a non-cooperative image acquisition system to generate descriptors for features in the segmented iris image that are tolerant of segmentation error. The method includes receiving a segmented iris image, and selecting feature points in the segmented iris image to describe an iris locally.
Type:
Application
Filed:
March 19, 2010
Publication date:
June 7, 2012
Applicant:
Indiana University Research & Technology Corporation
Abstract: In various embodiments, the present invention can involve a method of synthesizing ?-amino-?-caprolactam. The method can comprise heating a salt of L-lysine in a solvent comprising an alcohol. In other embodiments, the present invention can involve methods for synthesizing ?-caprolactam. The methods can comprise heating a salt of L-lysine in a solvent comprising an alcohol and deaminating the reaction product. In various embodiments, the invention can include methods of converting biomass into nylon 6. The methods can comprise heating L-lysine in a solvent comprising an alcohol to produce ?-amino-?caprolactam, deaminating to produce ?-caprolactam and polymerizing into nylon 6, wherein the L-lysine is derived from the biomass. In other embodiments, the present invention can include methods of making nylon 6. The methods can comprise synthesizing ?-caprolactam and then polymerizing, wherein the ?-caprolactam is derived from L-lysine.
Type:
Application
Filed:
July 1, 2011
Publication date:
June 7, 2012
Applicant:
Board of Trustees of Michigan State University
Abstract: A multilayered electroactive polymer (EAP) device and a method of manufacturing the same is provided. The multilayered EAP device includes a plurality of unit layers. Each unit layer includes an EAP layer formed of an electroactive polymer (EAP), a protecting layer configured to prevent a material from penetrating into the EAP layer, and an active electrode formed using a conductive material. The protecting layer may be formed below the active layer or above the active layer. The active electrode may be interposed between two protecting layers.