Abstract: The invention provides isolated N-methyl-D-aspartate type 3B (NR3B) polypeptides, functional fragments and peptides, encoding nucleic acid molecules and polynucleotides, and specific antibodies. Also provided are excitatory glycine receptors, containing either NR3B or NR3A polypeptides. Further provided are methods for detecting excitatory glycine receptor ligands, agonists and antagonists. The invention also provides related diagnostic and therapeutic methods.

Abstract: Massive parallel printing of structures and nanostructures, including lipids, at high speed with high resolution and high quality using two dimensional arrays comprising cantilevers and tip-based transfer of material to a surface. The invention provides a nanolithographic method comprising (1) providing a two-dimensional array of a plurality of cantilevers, wherein the array comprises a plurality of base rows, each base row comprising a plurality of cantilevers extending from the base row, wherein each of the cantilevers comprising tips at the cantilever end away from the base row; wherein the two dimensional array has a support; (2) providing a patterning composition, wherein the composition comprises one or more lipids; (3) providing a substrate; (4) coating the tips of the cantilevers with the patterning composition; and (5) depositing at least some of the patterning composition from the tips to the substrate surface.

Abstract: Site-specific Listeria integration vectors and methods for their use are provided. The subject vectors include a bacteriophage integrase gene and a bacteriophage attachment site, where in many embodiments the bacteriophage that is the source of these elements is a listeriophage. In certain embodiments, the subject vectors further include a multiple cloning site, where the multiple cloning site may further include a polypeptide coding sequence, e.g., for a heterologous antigen. The subject vectors and methods find use in a variety of different applications, including the study of Listeria species and the preparation of Listeria vaccines.

Abstract: The microstrip array antenna includes a dielectric substrate formed with a conductive ground plate at a back surface thereof, and strip conductors formed on a front surface of the dielectric substrate. The strip conductors includes a linear main feeding strip line, and a plurality of array elements connected to the main feeding strip line, the array elements being disposed at least one of both sides of the main feeding strip line at a predetermined interval along a longitudinal direction of the main feeding strip line. Each of the array elements includes a sub-feeding strip line connected to the main feeding strip line, a rectangular radiating antenna element connected to a terminal end of the sub-feeding strip line, and a stub connected to the sub-feeding strip line. The stub is disposed between the main feeding strip line and the radiating antenna element.

Abstract: In a plasma display device, one frame is divided into a plurality of subfields having respective luminance weights, and a first line load ratio is measured from a plurality of video signals corresponding to a first row electrode among a plurality of row electrodes during the respective subfields. A first output estimation weight of each subfield is set based on the first line load ratio of each subfield in the first row electrode. The plurality of video signals corresponding to the first row electrode are converted into a plurality of first subfield data based on the first output estimation weight, and a driving signal is applied to the first row electrode and the plurality of column electrodes according to the plurality of first subfield data.

Abstract: The cyclic prefix-based enhanced data recovery method retains the cyclic prefix (CP) upon reception and routes the CP to a data detection module to enhance the operation of the orthogonal frequency division multiplexed (OFDM) receiver whether operating in the blind, semi-blind, training, or perfectly known channel modes. Processing of the OFDM symbol and the CP is performed in the data detector and obtains data recovery by computing a maximum likelihood estimation based on the CP and the OFDM symbols.

Abstract: Compositions and methods for the detection, prevention, or treatment of anthrax or other infectious diseases. In one aspect, the present invention provides methods for immunizing humans or animals against Bacillus anthracis or other capsulated pathogens. The methods include administering a capsular polypeptide of a pathogen of interest and a CD40 agonist to a human or animal. The capsular polypeptide or the CD40 agonist is administered in such an amount or frequency that an immunoprotective response can be elicited in the human or animal against the pathogen of interest. In another aspect, the present invention provides methods of using passive immunization with anti-capsular polypeptide antibodies to prevent or treat infections caused by Bacillus anthracis or other pathogens. In yet another aspect, the present invention provides methods useful for diagnosis of anthrax by detection of capsular polypeptide in serum or other biological samples.

Abstract: A method for determining a composition of an object using a spectral x-ray system is provided. X-ray photons of at least two different energies are transmitted through the object. The energy of each detected x-ray photon using a detector in the x-ray system is estimated. A first weighted sum of the number of detected photons of each energy is found using a first weighting function, wherein the first weighting function is dependent on the attenuation coefficient function of a first material. In another embodiment, the photons are binned into two energy bins wherein there is a gap between the energy bins.

Abstract: Methods for the heteroepitaxial growth of smooth, high quality films of N-face GaN film grown by MOCVD are disclosed. Use of a misoriented substrate and possibly nitridizing the substrate allow for the growth of smooth N-face GaN and other Group III nitride films as disclosed herein. The present invention also avoids the typical large (?m sized) hexagonal features which make N-face GaN material unacceptable for device applications. The present invention allows for the growth of smooth, high quality films which makes the development of N-face devices possible.

Abstract: The present invention provides synthetic methods and compositions for treatment of autoimmune and anti-inflammatory disorders comprising administering an effective amount of a derivative of triptolide alone or in combination or alternation with other anti-autoimmune or anti-inflammatory compounds.

Abstract: Systems, apparatus and methods that use a hidden Markov model to estimate motion of a sample under measurement and to reduce a motion-induced effect in the measurement. MRI systems and other sample measurement systems can be implemented based on motion sensing using the hidden Markov model. Recursive and non-recursive estimation processes are described.

Abstract: An ignition system (10) comprises a spark plug (12) having a first end (14) defining a spark gap (16) between a first electrode (18) and a second electrode (20). A transformer (46) comprising a primary winding 44 and a secondary winding (50) also forms part of the system. The secondary winding is connected in a secondary circuit to the first electrode 18 and the secondary winding has a resistance of less than 1 k? and an inductance of less than 0.25 H. A drive circuit (26) is connected to the primary winding.

Abstract: Each micro electrode of a high-density micro electrode array is connected to the same conducting wire. Serial switches enable sequential electrical connection of the micro electrode array. Given reasonable temporal resolution, the separation interval of two consecutive instances of the same micro electrode entering the ON state matches the temporal resolution. The micro electrode array has simple layout and small area, thereby maximizing the number of micro electrodes installed per unit area.

Abstract: Scanning probe microscope (SPM) images are enhanced by enforcing one or more symmetries that can be selected based on suitable Fourier coefficient amplitude or phase angle residuals, and/or geometric Akaike information criteria, and/or cross correlation techniques. Alternatively, this selection can be based on prior knowledge of specimen characteristics. In addition, a scanning microscope point spread function is obtained based on the evaluation of a calibration image by enforcing at least one symmetry and can be applied to other image acquisitions.

Abstract: Disclosed are short chain peptides that are constrained to adopt an alpha helical conformation and their use as alpha helical scaffolds for directing amino acid side chains into positions analogous to those found in longer chain alpha helical peptides. Also disclosed is the use of these peptides for attaching peptidic or non-peptidic appendages in order to mimic side chains of longer alpha helical peptides. The peptides find use in mimicking naturally occurring peptides or proteins or in preparing new materials.

Abstract: The present invention features polypeptides having activity of human neurogenin3 (hNgn3), and nucleic acid encoding such polypeptide. The invention also features use of islet transcription factors such as hNgn3 to facilitate production of pancreatic islet cells from progenitor cells, and to facilitate insulin delivery by production of islet cells so produced.

Abstract: A gaming terminal runs a base game and a special game simultaneously; awards a payout according to a result of the base game; awards the number of chance flags according to a result of the chance game; accumulatively stores, in a terminal storage unit, the number of chance flags in association with ID data and a PIN code; when ID data is newly inputted, determines whether the ID data is correct, referring to the original ID data stored; when the ID data is incorrect, determines whether the PIN code inputted through a PIN code input device is correct, referring to the PIN code stored; when the PIN code is incorrect, initializes the number of chance flags associated with the original ID data stored; when the PIN code is correct, stores the ID data newly inputted, replacing the original ID data stored.

Abstract: An apparatus and method for treating morbid obesity in mammals using a gastric reduction assembly that reduces the gastric volume of a stomach and induces early satiety. The gastric reduction assembly comprises at least two or more expandable devices, each able to be adjustably inflated with a fluid (e.g., a liquid or a gas) using a filling tube. In a preferred embodiment, the gastric reduction assembly is inserted through the abdominal wall and placed at a location exterior to the stomach body, avoiding an abdominal incision. Once positioned near the stomach body, the gastric reduction assembly allows for the external compression of the stomach body to limit food intake. The gastric reduction assembly also minimizes the potential for shifting of the expandable devices after insertion to the stomach body to revert to its pre-compressed state.

Abstract: RNA interference using small interfering RNAs which are specific for the ICAM-1 gene inhibits expression of this gene. Diseases which involve ICAM-1-mediated cell adhesion, such as inflammatory and autoimmune diseases, diabetic retinopathy and other complications arising from type I diabetes, age related macular degeneration and many types of cancer, can be treated by administering the small interfering RNAs.

Abstract: An exemplary, highly integrated, SPM-based system for measuring the conductivity and/or force of substance under programmable engaging/stretching processes is described. A sample bias is applied across two electrodes. A substance to be measured is sandwiched between them. A first electrode is first brought relative to a second electrode (engaging) in programmable pathways that can be described as stretching distance versus time curves. The process of engaging the electrodes continues until a certain current reached, a certain force reached and whichever case happens first. The electrodes are then separated (stretching) in programmable pathways that can be described as stretching distance versus time curves. A periodic modulation can be applied to the engaging/stretching process to realize different stretch pathways. The sample bias across the electrodes is kept constant or swept in a programmable shape over time, described as a voltage-versus time curve.