Abstract: Provided are a cell chip and a system thereof that are capable of detecting optimal conditions for stem cell differentiation by mechanical stimuli. The cell chip for cell differentiation experimentation includes a plurality of cell chambers for storing cells and culture media, cell and culture medium injection ports for transferring the cells and culture media to corresponding cell chambers, fine passages for moving the cells and the culture media injected into the cell and culture medium injection ports to the cell chambers, pneumatic injection ports for injecting pneumatic pressures applied to the cell chambers, and apertures having circular films for transferring the pneumatic pressures injected through the pneumatic injection ports to corresponding cell chambers. Here, at least two of the apertures may have different areas to vary the magnitude of pneumatic pressure applied to corresponding cell chambers.

Abstract: The present invention provides an exchangeable, reagent pre-loaded sheets which can be temporarily applied to an electrode array on a digital microfluidic device (DMF). The substrate facilitates virtually un-limited re-use of the DMF devices avoiding cross-contamination on the electrode array itself, as well as enabling rapid exchange of pre-loaded reagents while bridging the world-to-chip interface of DMF devices. The present invention allows for the transformation of DMF into a versatile platform for lab-on-a-chip applications.

Abstract: Methods and systems to detect changes in a region of space relative to baseline measurements, including to process data to detect potential objects, or contacts against a natural background environment, to characterize and geo-register the contacts, to compare and correlate the contacts with a database of known objects, and to report uncorrelated contacts as new objects in the space. Features disclosed herein may be implemented to process image data from a line-by-line image-generation system including, for example, side-looking sonar. Methods and system may be implemented with respect to multi-frequency band sonar data.

Abstract: The present invention describes the use of EDTA and/or alkali treated hard brine at high pH for making ASP formulations for EOR applications.

Abstract: An organometal material gas is supplied into a low electron temperature and high density plasma excited by microwaves to form a thin film of a compound on a substrate as a film forming object. In this case, the temperature of a supply system for the organometal material gas is controlled by taking advantage of the relationship between the vapor pressure and temperature of the organometal material gas.

Abstract: A method for compressing and transmitting a sequence of video frames represented by arrays of digital pixel values includes the following steps: transmitting a representation of a first frame (I1) of the sequence; deriving a sorting permutation P1 of the first frame; using the sorting permutation of the first frame, P1, to approximately sort a second frame (I2) of the sequence, to obtain approximately sorted frame P1(I2); and compressing and transmitting the approximately sorted frame P1(I2).

Abstract: A gaming system 10, composed of a server 11 and a plurality of gaming terminals 13, submits selection information including a game type to be executed in a gaming terminal 13 and a picture type, selected by a player in the gaming terminal 13, and operational information indicating operational status to the server 11. The server 11 aggregates the information received from the plurality of gaming terminals 13, and submits the game type and the picture type most selected, as configuration information, to the plurality of gaming terminals 13. In addition, operational information and processing results of the server 11 are displayed on a monitor 16. The gaming terminal 13 changes a stand-by screen in accordance with the configuration information and displays the stand-by screen on liquid crystal displays 30 and 40.

Abstract: An electrical energy storage device (20,70) includes a substrate (22), which is formed so as to define a multiplicity of micro-containers separated by electrically-insulating and ion-conducting walls (32). A first plurality of anodes (A) is disposed in a first subset (24) of the micro-containers, and a second plurality of cathodes (C) is disposed in a second subset (26) of the micro-containers. The anodes and cathodes are arranged in an interlaced pattern.

Abstract: A new strategy for the quantitative determination of enantiomeric purity that combines guest-host complexation, spectroscopy, and chemometric modeling. Spectral data for samples of known enantiomeric composition is subjected to a type of multivariate regression modeling known as partial least squares (“PLS-1”) regression. The PLS-1 regression produces a mathematical model that can be used to predict the enantiomeric composition of a set of samples of unknown enantiomeric purity. In this strategy, the concentration of the chiral compound does not have to be fixed or known.

Abstract: A bathing chair which has a water-spraying function for simultaneously effecting a shower discharge from each of a plurality of shower discharge ends and thus assist a person with severe disabilities while cleansing him or herself or while being assisted by a third person. The bathing chair including strategically located nozzles to wash critical body parts, a main control system with manual and electro-mechanical operated valves, two main flow paths with independent control systems, means for combining a soap product and water, a water temperature sensor, and a pump/reservoir system for water pressure adjustment.

Abstract: The present invention relates to a peptide, which specifically homes to the intracranial, early stage astrocytoma model that grows as islets and harbors co-opted tumor vessels in the brain. The peptide finds its use in targeted delivery of therapeutic substances to invasive brain cancer or metastatic brain lesions as such and in combination with conventional therapies, such as surgery and radiation, and anti-angiogenic therapies, and as a tool in diagnosis of, e.g., invasive brain cancer or metastatic brain lesions.

Abstract: A method and a computer-readable medium containing computer program for encoding a frame of video data are presented. The frame of video data has a plurality of macro-blocks. Each of the macro-blocks includes a macro-block header having multiple elements and macro-block residue data. An element of the macro-block header is encoded based on the value of the same element of a previous macro-block header so as to reduce overall bits in the macro-block header. The element of the macro-block header is encoded by grouping the elements of the plurality of the macro-blocks.

Abstract: Generating and using a high-speed, scalable, and easily updateable data structure are described. The proposed data structure provides minimal perfect hashing functionality while intrinsically supporting low-cost set-membership queries. In other words, in some embodiments, it provides at most one match candidate in a set of known arbitrary-length bit strings that is used to match the query.

Abstract: The present invention relates to a hierarchical system and method for task assignment (TA), coordination and communication of multiple Unmanned Aerial Vehicles (DAV's) engaging multiple attack targets and conceives an ad-hoc routing algorithm for synchronization of target lists utilizing a distributed computing topology. Assuming limited communication bandwidth and range, coordination of UAV motion is achieved by implementing a simple behavioral flocking algorithm utilizing a tree topology for target list routing. The TA algorithm is based on a graph-theoretic approach, in which a node locates all the detectable targets, identifies them and computes its distance to each target. The node then produces an attack plan that minimizes the sum of distances of the UAV's in the subtree of a given node to the targets.

Abstract: The present invention discloses the protease stratum corneum chymotrytic enzyme (SCCE) is specifically over-expressed in ovarian and other malignancies. A number of SCCE peptides can induce immune responses to SCCE, thereby demonstrating the potential of these peptides in monitoring and the development of immunotherapies for ovarian and other malignancies.

Abstract: The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.

Abstract: Novel compounds useful for inhibiting the 90kDa heat shock proteins containing a quinone-like moiety and a di-hydroxy phenol like moiety, similar to geldanamycin and radicicol.

Abstract: The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.

Abstract: A system includes emission of a first treatment beam associated with a first energy toward a neutron dose detector, determination of a first number of soft errors experienced by a semiconductor-based device exposed to neutrons generated by the first treatment beam, determination of a first neutron dose based on the first treatment beam using the neutron dose detector, and association of the first energy of the first treatment beam with the first number of soft errors and the first neutron dose. Some aspects include emission of a second treatment beam associated with the first energy toward a target, determination of a second number of soft errors experienced by the semiconductor-based device exposed to neutrons generated by the second treatment beam, and determination of a second neutron dose at the target based on the association between the first energy, the first number of soft errors and the first neutron dose.

Abstract: The present invention provides for novel assays and the use of such assays for screening compounds that affect PGRMC1's and related homologue's ability to catalyze the incorporation of cholesterol into membranes. The present invention also provides for methods and compositions for affecting incorporation of cholesterol into membranes. The invention also provides for diagnostic and therapeutic kits for the methods described herein.