Abstract: Provided herein are methods for in-vivo assessment of intraventricular flow shear stress, risk of hemolysis, also the location and extent of blood flow stasis regions and inside a cardiac chamber or blood vessel. Also provided herein are systems for performing such methods. Also provided herein are methods for assessing hemolysis and/or thrombosis risk in patients implanted with an LVAD. LVAD positioning and/or speed may be adjusted based on the results obtained by using methods described herein, and the risk for hemolysis and/or thrombosis can be minimized.
Type:
Grant
Filed:
September 28, 2022
Date of Patent:
March 25, 2025
Assignee:
The Regents of the University of California et al.
Inventors:
Juan Carlos del Alamo de Pedro, Lorenzo Rossini, Andrew Kahn, Javier Bermejo, Pablo Martínez-Legazpi, Raquel Yotti Alvarez
Abstract: A method of calculating a soil moisture profile includes obtaining a capacitance measurement of a soil surface at a location, applying a preselected calibration to the capacitance measurement to obtain a top surface moisture estimate, obtaining local climatic and hydrological data correlated with the location, the local climatic and hydrological data, which includes at least local water input data, and calculating an estimate of the soil moisture at the location by applying a preselected evapotranspiration model to the top surface moisture estimate and the local climatic and hydrological data.
Type:
Grant
Filed:
August 2, 2021
Date of Patent:
March 25, 2025
Assignee:
The University of Melbourne
Inventors:
Amir Orangi, Guillermo Andres Narsilio Ferrero
Abstract: Aspects of the invention described herein include methods of treating, inhibiting, ameliorating and/or eliminating a virus or cancer cells in a subject utilizing genetically engineered human T-cells having receptors for a molecule presented by the virus or the cancer cells, wherein the genetically engineered T cells are isolated utilizing a two-stage MTX selection that employs increasing concentrations of MTX.
Type:
Grant
Filed:
November 12, 2020
Date of Patent:
March 25, 2025
Assignees:
Seattle Children's Hospital, University of Washington
Inventors:
Michael C. Jensen, Suzie Pun, Nataly Kacherovsky
Abstract: The present disclosure provides for porous polymer materials that include an ordered array of voids separated by a polymer framework. The porous polymer material can have a recovery state where the voids are in an uncollapsed state and iridescent color, and a deformed state having voids in a collapsed state that is non-iridescent or substantially transparent. The materials can have regions of both states simultaneously. Also described are methods for fabricating a polymer material as above, as well as chromogenic sensors including the polymer material. The sensors can have hidden anti-counterfeiting patterns, hydrophobic/oleophobic properties, and chromogenic transformation can be triggered by various stimuli such as solid target compounds, light energy, and more.
Type:
Grant
Filed:
February 13, 2019
Date of Patent:
March 25, 2025
Assignee:
University of Florida Research Foundation, INC.
Abstract: An Empirical Mode Decomposition (EMD)-based noise estimation process is disclosed herein that allows for blind estimations of noise power for a given signal under test. The EMD-based noise estimation process is non-parametric and adaptive to a signal, which allows the EMD-based noise estimation process to operate without necessarily having a priori knowledge about the received signal. Existing approaches to spectrum sensing such as Energy Detector (ED) and Maximum Eigenvalue Detector (MED), for example, may be modified to utilize a EMD-based noise estimation process consistent with the present disclosure to shift the same from semi-blind category to fully-blind category.
Type:
Grant
Filed:
October 29, 2021
Date of Patent:
March 25, 2025
Assignee:
The University of New Hampshire
Inventors:
Mahdi H. Al-Badrawi, Nicholas J. Kirsch, Bessam Z. Al-Jewad
Abstract: Embodiments of the present disclosure provide for lubricious structures (also referred to simply as “structure”), methods of making lubricious structures, methods of using lubricious structures, and the like.
Type:
Grant
Filed:
October 26, 2022
Date of Patent:
March 25, 2025
Assignee:
University of Florida Research Foundation, INC.
Inventors:
Scott S. Perry, Alexander Rudy, Wallace Gregory Sawyer, Thomas Ettor Angelini
Abstract: Systems, methods, and media for displaying interactive augmented reality presentations are provided. In some embodiments, a system comprises: a head mounted display comprising: a transparent display; a plurality of sensors; and at least one processor, wherein the at least one processor is programmed to: select a content display location of a plurality of predetermined content display locations to use to present content based at least in part on a location of the head mounted display within a current physical environment; and cause content to be presented by the head mounted display anchored at the selected content display location.
Type:
Grant
Filed:
May 7, 2024
Date of Patent:
March 25, 2025
Assignee:
Case Western Reserve University
Inventors:
Mark A. Griswold, Henry Eastman, Robert Gotschall
Abstract: This application relates to a device and a method for calculating a fault ratio. The method may include by using image frames collected from a camera of a first vehicle, generating a driving route in which the first vehicle travels, and acquiring fault information of a traffic accident involving a second vehicle, the traffic accident being related to the driving route of the first vehicle. The method may also include changing factors related to braking or steering of the first vehicle and the second vehicle, and generating multiple simulation driving scenarios by simulating the driving route on the basis of the changed factors. The method may further include computing a fault ratio of the first vehicle and the second vehicle for each of the multiple simulation driving scenarios by correcting the fault information on the basis of the factors.
Type:
Grant
Filed:
April 26, 2022
Date of Patent:
March 25, 2025
Assignee:
Kookmin University Industry Academy Cooperation Foundation
Inventors:
Jin Woo Yoo, Jin Gwan Kim, Dong Sun Lim, Hoo Kyung Lee
Abstract: The present techniques may provide improved processing and functionality of performance of the 128-bit AES Algorithm, which may provide improved power consumption. For example, in an embodiment, an encryption and decryption apparatus may comprise memory storing a current state matrix of an encryption or decryption process and a plurality of multiplexers configured to receive from the memory current elements of the state matrix stored in the memory, perform a cyclic shift on the received elements of the state matrix, and transmit the shifted elements to the memory for storage as a new state matrix.
Type:
Grant
Filed:
November 30, 2023
Date of Patent:
March 25, 2025
Assignee:
The Board of Regents of the University of Texas System
Abstract: An image encoding/decoding method and apparatus are provided. An image encoding method performed by an image encoding apparatus may comprise determining an intra-prediction mode of a current block, configuring a reference sample of intra prediction by using at least one of a neighbor pixel of the current block in a current picture and a pixel of a reference picture, and performing intra prediction for the current block based on the intra-prediction mode and the reference sample.
Type:
Grant
Filed:
October 2, 2023
Date of Patent:
March 25, 2025
Assignees:
Electronics and Telecommunications Research Institute, University-Industry Cooperation Group of Kyung Hee University
Inventors:
Jung Won Kang, Hyun Suk Ko, Sung Chang Lim, Jin Ho Lee, Ha Hyun Lee, Dong San Jun, Seung Hyun Cho, Hui Yong Kim, Jin Soo Choi, Gwang Hoon Park, Tae Hyun Kim, Dae Young Lee
Abstract: This discloses that compounds of Formula 1 may be used as antifibrotics because they inhibit type 1 collagen production. In particular, this discloses a pharmaceutical composition containing one or more compounds of Formula 1 and methods of using compounds of Formula 1 in fibrosis treatment and inhibiting type 1 collagen synthesis.
Type:
Grant
Filed:
November 22, 2022
Date of Patent:
March 25, 2025
Assignee:
Florida State University Research Foundation, Inc.
Abstract: The disclosure relates polyoxometalate complexes and uses in the management, treatment, or prevention of cancer. In certain embodiments, the polyoxometalate complexes comprise polydentate oxygen bridging ligands such as those of the following formula: [POM{(OCH2)3CX}2], [M6O13{(OCH2)3CX}2], [V6O13{(OCH2)3CX}2], salts, or derivatives thereof wherein POM is a polyoxometalate, M is a metal, and X is defined herein. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising polyoxometalate complexes disclosed herein.
Abstract: A gas compressing system including a plurality of n compressors connected in parallel. Each compressor has a suction line connected to a common suction manifold and a discharge line connected to a common discharge manifold configured to deliver compressed gas to a downstream load. The system also includes a process controller configured to control an average speed of the compressors based upon a discharge pressure in the common discharge manifold or a discharge flow through the common discharge manifold. The system further includes an adaptive load sharing optimizing controller configured to determine the speed of each compressor in the plurality of n compressors. A method of controlling a gas compressing system is also provided.
Type:
Grant
Filed:
February 2, 2021
Date of Patent:
March 25, 2025
Assignee:
Khalifa University of Science and Technology
Inventors:
Khalifa Al Hosani, Igor Boiko, Mohammad Luai Hammadih, Ayman Al Zawaideh
Abstract: A conformal graphene-encapsulated battery electrode material is formed by: (1) coating a battery electrode material with a metal catalyst to form a metal catalyst-coated battery electrode material; (2) growing graphene on the metal catalyst-coated battery electrode material to form a graphene cage encapsulating the metal catalyst-coated battery electrode material; and (3) at least partially removing the metal catalyst to form a void inside the graphene cage.
Type:
Grant
Filed:
November 23, 2020
Date of Patent:
March 25, 2025
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: The present disclosure provides CasY proteins, nucleic acids encoding the CasY proteins, and modified host cells comprising the CasY proteins and/or nucleic acids encoding same. CasY proteins are useful in a variety of applications, which are provided. The present disclosure provides CasY guide RNAs that bind to and provide sequence specificity to the CasY proteins, nucleic acids encoding the CasY guide RNAs, and modified host cells comprising the CasY guide RNAs and/or nucleic acids encoding same. CasY guide RNAs are useful in a variety of applications, which are provided. The present disclosure provides methods of identifying a CRISPR RNA-guided endonuclease.
Type:
Grant
Filed:
May 19, 2022
Date of Patent:
March 25, 2025
Assignee:
The Regents of the University of California
Inventors:
Jennifer A. Doudna, Jillian F. Banfield, David Burstein, Lucas Benjamin Harrington
Abstract: A CT scanning method compensates gantry motion blurring in projection measurement based on synchronized focal spot movement and detector data shifting. Tube power is increased by moving the focal on the target and reducing focal spot dwell duration. The CT scanning method is used on helical CT and cone beam with a rotating anode source and CBCT and TBCT with a linear array x-ray source.
Type:
Grant
Filed:
November 8, 2022
Date of Patent:
March 25, 2025
Assignee:
Washington University
Inventors:
Tiezhi Zhang, Qinghao Chen, Shuang Zhou, Yuewen Tan
Abstract: An embodiment of the present disclosure relates to a learning method of a one-shot imitation method based on an artificial neural network model that adaptively one-shot imitates a video demonstration of an expert, wherein the method includes: a first stage of learning to infer a semantic skill sequence from a given expert demonstration; a second stage of learning to infer dynamics based on state-action pairs, which are the minimum units that form an action trajectory of the expert in the given expert demonstration; and a third stage of learning to create an action sequence by combining the inferred semantic skill sequence and dynamics based on given environmental data.
Type:
Application
Filed:
August 23, 2024
Publication date:
March 20, 2025
Applicant:
Research & Business Foundation Sungkyunkwan University
Abstract: Compositions, devices, and methods for sensing free radicals such as hydroxyl radicals, involving cerium oxide nanoparticles, metal nanoparticles, and a conductive support on an electrode, are described.
Type:
Application
Filed:
September 19, 2023
Publication date:
March 20, 2025
Applicant:
The University of Toledo
Inventors:
Dong Shik Kim, Ana C. Alba Rubio, Hamidreza Ghaedamini, Surachet Duanghathaipornsuk, Ibeh S. Omodolor
Abstract: A scholar system and method transforms search of academic knowledge. The system uses a combination of face recognition and language generation technology to effortlessly capture scholars in photos to give rich summaries of profiles of their work. The system also offers an interactive chat element for users to get more insights about a scholar, reducing online search efforts. The system ensures privacy and ethical compliance to rules and regulations.
Type:
Application
Filed:
May 23, 2024
Publication date:
March 20, 2025
Applicant:
Mohamed bin Zayed University of Artificial Intelligence
Inventors:
Wong Yu KANG, Toluwani AREMU, Younes BALAH, Abdulmotaleb EL SADDIK, Maryam NADEEM, Ivo Gollini NAVARRETE
Abstract: Disclosed herein are genetically modified plants having altered biological activity of 3-?-hydroxysteroid dehydrogenase/isomerase (GAME25), or 2-oxoglutarate-dependent dioxygenase (GAME31), or a combination thereof, wherein the genetically modified plants have an altered content of at least one cholesterol derived compound selected from the group including a steroidal alkaloid or a glycosylated derivative thereof and an unsaturated or saturated steroidal saponin or a glycoside derivative thereof. Further disclosed herein are genetically modified plants having altered expression of a gene encoding a 3-?-hydroxysteroid dehydrogenase/isomerase (GAME25), or a 2-oxoglutarate-dependent dioxygenase (GAME31), or a combination thereof, wherein the genetically modified plant has an altered content of at least one cholesterol derived compound selected from the group including a steroidal alkaloid or a glycosylated derivative thereof and an unsaturated or saturated steroidal saponin or a glycoside derivative thereof.
Type:
Application
Filed:
October 9, 2024
Publication date:
March 20, 2025
Applicants:
Yeda Research and Development Co. Ltd., Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
Inventors:
Asaph AHARONI, Prashant SONAWANE, Pablo D. CARDENAS, Saul BURDMAN