Abstract: Aspects of the disclosure relate to a nucleic acid comprising a heterologous nucleic acid insert flanked by interrupted self-complementary sequences, wherein one self-complementary sequence is interrupted by a cross-arm sequence forming two opposing, lengthwise-symmetric stem-loops, and wherein the other of the self-complementary sequences is interrupted by a truncated cross-arm sequence. Methods of delivering the nucleic acid to a cell are also provided.

Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.

Abstract: Novel dinuclear silver(I) pyrazolido complexes and methods of synthesizing them are provided. Advantageously, the novel silver(I) pyrazolido complexes have excellent antimicrobial activity and methods of using said complexes to treat bacterial, fungal, and viral infections are also provided.

Abstract: A wound dressing includes: a structural material formed into a dressing; at least one immunomodulatory agent associated with the dressing; and a growth factor associated with the dressing. A wound dressing kit includes: a structural material formed into a wound dressing; an immunomodulatory agent; and a growth factor composition, wherein the structural material contains the immunomodulatory agent and/or the immunomodulatory agent in a separate composition. A method of treating a wound in a tissue includes: applying an immunomodulatory agent to the wound; applying a wound dressing to the wound; and allowing the wound to heal with the immunomodulatory agent and wound dressing. The application of a growth factor can be before, during and/or after applying the wound dressing to the wound.

Abstract: A method for froth-controlled flotation of argillaceous lepidolite ore, including: crushing and grinding an ore, adding water to obtain pulp; adding agents thereto, and conducting roughing to obtain roughing concentrate and roughing tailing; adding agents to the roughing tailing, and conducting first scavenging to obtain first scavenging concentrate and first scavenging tailing; subjecting the first scavenging tailing to second scavenging to obtain second scavenging concentrate and second scavenging tailing; adding agents to the roughing concentrate, conducting first cleaning to obtain first cleaning concentrate and first cleaning tailing; subjecting the first cleaning concentrate to second cleaning to obtain lithium concentrate I and second cleaning tailing; combining the first scavenging concentrate, second scavenging concentrate, first cleaning tailing, and second cleaning tailing to obtain lithium-containing mixed middling, adding agents thereto, and conducting cleaning-scavenging to obtain lithium concen

Abstract: The present disclosure relates to a composite-strengthened heat-resistant and wear-resistant aluminum alloy and a preparation method thereof, and belongs to the field of preparation of high-performance metal materials. In the composite-strengthened heat-resistant and wear-resistant aluminum alloy of the present disclosure, an Al—Si—Cu—Mg alloy is adopted as a matrix, and microalloying elements for improving the heat resistance and a heat-resistant high-entropy alloy (HEA) for improving the wear resistance are added to allow composite strengthening. The preparation method mainly includes the following steps sequentially: smelting and alloying, blowing and refining, blow-compounding, die-casting molding, solution treatment, water quenching, and cryogenic and aging composite heat treatment.

Abstract: The present disclosure relates to the field of G protein coupled receptor (GPCR) structural biology and signaling. In particular, the present disclosure relates to binding domains directed against and/or specifically binding to GPCR:G protein complexes. Also provided are nucleic acid sequences encoding such binding domains and cells expressing or capable of expressing such binding domains. The binding domains of the present disclosure can be used as universal tools for the structural and functional characterization of G-protein coupled receptors in complex with downstream heterotrimeric G proteins and bound to various natural or synthetic ligands, for investigating the dynamic features of G protein activation, as well as for screening and drug discovery efforts that make use of GPCR:G protein complexes.

Abstract: Aiming at the problem of slow crystallization rate of poly(ethylene furandicarboxylate) (PEF), a preparation method for a bio-based nucleating agent for PEF and an application thereof are disclosed. In a technical solution, glycine having a bio-based source is subjected to an amidation reaction with furoic acid under the catalysis of p-toluenesulfonic acid, followed by an acid-base neutralization reaction with sodium hydroxide to obtain a bio-based nucleating agent for PEF. The bio-based nucleating agent prepared by the present disclosure can significantly accelerate a crystallization rate of PEF. Most importantly, the bio-based nucleating agent has no effect on the bio-based properties of PEF.

Abstract: A method of preparing an electret by saturating a nonwoven fabric with a liquid, such as water, and removing the liquid via suction to generate charges by friction between the fabric fibers and the liquid is described. The saturating can be carried out, for example, by impinging the bottom side of the fabric with a jet or jets of water while the fabric is being pulled under a solid roller. Excess water can also be applied during a water quenching step of a meltblowing or spunbonding process. An apparatus for preparing an electret according to the presently disclosed methods is also described.

Abstract: Systems and methods presented herein include guest activity detection devices configured to detect activity of guests of an amusement park, and to send data indicative of the detected activity; an artificial intelligence entity management system configured to analyze the data indicative of the activity of the guests, and to modify properties of guest-specific artificial intelligence entities based at least in part on the analyzed data indicative of the activity of the guests; and park features disposed within a physical environment of the amusement park and configured to be instructed by the guest-specific artificial intelligence entities to modify a guest experience for the guests of the amusement park in accordance with the properties of the guest-specific artificial intelligence entities.

Abstract: Provided is a thrombin-carrying hemostatic sheet that is suitable for hemostasis during surgery, in particular, for hemostasis during spine surgery, that is convenient without preparation before use, and that is bioabsorbable and can be embedded in the body as it is. The hemostatic sheet is composed of a gelatin sponge carrying an effective amount of thrombin, wherein (A) the density is 30 to 55 mg/cm3, and (B) the shape maintaining angle in wet conditions is 55 to 120°.

Abstract: Systems and methods for blood flow control are described herein. In some variations, a blood flow control system may comprise a blood flow control device. The blood flow control device may be placed within a body of a patient and may comprise an expandable member and a sensor. The sensor may be configured to measure at least one of a physiologic condition of the patient and a pressure associated with the expandable member. The blood flow control system may include at least one controller communicably coupled to the sensor to: receive data indicative of at least one of the physiologic condition of the patient and the pressure associated with the expandable member from the sensor, compare the received data with target data, identify at least one error based on the comparison, and in response to identifying the error, inhibit at least one function of the blood flow control system.

Abstract: A method includes determining, by a control system, from among a plurality of categories, a current category of an incoming wind approaching a wind turbine, and setting, by the control system, a yaw bias of the wind turbine based on the current category. In some examples, the plurality of categories includes two or more wind conditions, such as a first wind condition in which wind contacting an upper rotor of the wind turbine is veering and wind contacting a lower rotor of the wind turbine is veering, a second wind condition in which the wind contacting the upper rotor of the wind turbine is veering and the wind contacting the lower rotor of the wind turbine is backing, and so on.

Abstract: Embodiments of the present invention relate to mechanically-activated microcapsules (MAMCs) for controlled drug-delivery, wherein the MAMCs release one or more active ingredients in response to mechanical stimuli in a subject's body. The MAMCs provide a platform for stimulating biological regeneration, biological repair, modifying disease, and/or controlling disease in mechanically-loaded musculoskeletal tissues.

Abstract: The disclosure claims a method of stimulating a conditional quantum master equation in a quantum transport process by a recurrent neural network, comprising the following steps of: establishing a recurrent neural network which is a long short term memory network (LSTM), wherein the LSTM comprises TLSTM cells arranged in chronological order, and each LSTM cell has an input value xt and an output value ht, and there is a parameter (W, b) in the LSTM cell; replacing the input value xt with a shot noise spectrum S(?) of the current obtained according to the conditional quantum master equation; replacing the output value ht with a trace of density matrices in the conditional quantum master equation; and replacing the parameter (W, b) with a connection between density matrices in the conditional quantum master equation at imminent moments.

Abstract: A method for treating endometrial cancer comprising: administering to a patient a cannabis extract (CE) wherein the cannabis extract comprises cannabidiol (CBD) at between 50% and 99% by weight of the CE.

Abstract: The design of bifunctional catalysts for water splitting by modifying the electronic structure of the catalyst. That bifunctional catalyst that is synthesized is a quaternary FeNi—PSe nanoporous film (FeNi—PSe NF). A self-supported FeNi—PSE NF is synthesized and used as an anode and a cathode in a two-electrode electrolytic cell. The cell is subjected to a water source, and the FeNi—PSe NFs split the water molecules to produce hydrogen fuel. The slightly oxidized FeNi—PSe surface serves as an active site for oxygen evolution reactions, making hydrogen evolution reactions and oxygen evolution reactions well-balanced, thereby improving electrolysis efficiency.

Abstract: The present disclosure relates to an antifungal composition including propylene glycol, caprylic acid, and carvacrol as active ingredients.

Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.

Abstract: An interactive portrait system includes a camera configured to capture imagery of an environment and a controller. The controller is configured to analyze the imagery to identify a guest in the environment, instruct an output device to provide an initial output to attempt to interact with the guest, and analyze the imagery to identify a behavior of the guest during the initial output, after the initial output, or both. The controller is also configured to evaluate the behavior of the guest using one or more artificial intelligence algorithms to determine whether the guest responded to the initial output. The controller is further configured to, in response to determining that the guest responded to the initial output, instruct the output device to provide an additional output to continue to attempt to interact with the guest.