Abstract: The present disclosure relates to the technical field of anti-aging preparations for skin, and especially relates to an anti-aging preparation for skin and an application thereof. Components of the anti-aging preparation for skin includes a 4-[(1E)-2-[[(4-chlorophenyl)methyl]sulfonyl]alkyne]-benzoic acid and/or a salt thereof. In the present disclosure, the anti-aging effect of the 4-[(1E)-2-[[(4-chlorophenyl)methyl]sulfonyl]alkyne]-benzoic acid and the salt thereof (such as sodium 4-[(1E)-2-[[(4-chlorophenyl)methyl]sulfonyl]alkyne]-benzoate) on skin has been discovered, and the 4-[(1E)-2-[[(4-chlorophenyl)methyl]sulfonyl]alkyne]-benzoic acid and the salt thereof can be applied in preparing the anti-aging preparation for skin that has good anti-aging effect on skin.

Abstract: A multiple scenario-oriented item retrieval method and system. The method includes the steps of extracting, by Hashing learning, image features from an image training set to train a pre-built item retrieval model; when an image is in a scenario of hard samples, introducing an adaptive similarity matrix, optimizing the similarity matrix by an image transfer matrix, constructing an adaptive similarity matrix objective function in combination with an image category label; constructing a loss quantization objective function between the image and a Hash code according to the image transfer matrix; when the image is in a scenario of zero samples, introducing an asymmetric similarity matrix, constructing an objective function by taking the image category label as supervisory information in combination with equilibrium and decorrelation constraints of the Hash code; and training the item retrieval model based on the above objective function to obtain a retrieved result of a target item image.

Abstract: An interactive portrait system includes a camera configured to capture imagery of an environment and a controller. The controller is configured to analyze the imagery to identify a guest in the environment, instruct an output device to provide an initial output to attempt to interact with the guest, and analyze the imagery to identify a behavior of the guest during the initial output, after the initial output, or both. The controller is also configured to evaluate the behavior of the guest using one or more artificial intelligence algorithms to determine whether the guest responded to the initial output. The controller is further configured to, in response to determining that the guest responded to the initial output, instruct the output device to provide an additional output to continue to attempt to interact with the guest.

Abstract: The design of bifunctional catalysts for water splitting by modifying the electronic structure of the catalyst. That bifunctional catalyst that is synthesized is a quaternary FeNi—PSe nanoporous film (FeNi—PSe NF). A self-supported FeNi—PSE NF is synthesized and used as an anode and a cathode in a two-electrode electrolytic cell. The cell is subjected to a water source, and the FeNi—PSe NFs split the water molecules to produce hydrogen fuel. The slightly oxidized FeNi—PSe surface serves as an active site for oxygen evolution reactions, making hydrogen evolution reactions and oxygen evolution reactions well-balanced, thereby improving electrolysis efficiency.

Abstract: Systems and methods for blood flow control are described herein. In some variations, a blood flow control system may comprise a blood flow control device. The blood flow control device may be placed within a body of a patient and may comprise an expandable member and a sensor. The sensor may be configured to measure at least one of a physiologic condition of the patient and a pressure associated with the expandable member. The blood flow control system may include at least one controller communicably coupled to the sensor to: receive data indicative of at least one of the physiologic condition of the patient and the pressure associated with the expandable member from the sensor, compare the received data with target data, identify at least one error based on the comparison, and in response to identifying the error, inhibit at least one function of the blood flow control system.

Abstract: The disclosure discloses a point-of-interest recommendation method based on a temporal knowledge graph. Based on the historical behavior trajectory of the user and multimodal information, the disclosure constructs a dynamic temporal knowledge graph and a static group knowledge graph, which are used to learn interest preferences of the user that change over time and stable features that do not change over time, respectively. At the same time, the disclosure uses deep learning methods to build a point-of-interest recommendation model, which can extract a point-of-interest fusion feature representation and a user fusion feature representation from the two knowledge graphs in combination with a user review sentiment embedding sequence to accurately predict a point of interest most likely to be visited by the target user at a next moment. The disclosure has the characteristics of high precision and strong scalability, and can provide support for personalized user behavior trajectory prediction.

Abstract: In the technical field of power generation, a method and system for directly and rapidly detecting 14C of carbon dioxide, which can quickly complete a 14C activity measurement of carbon dioxide, while further improving uniformity and accuracy for directly and rapidly detecting 14C of carbon dioxide. The method includes: pressurizing and liquefying gaseous carbon dioxide to obtain liquid carbon dioxide; mixing the liquid carbon dioxide with a cosolvent and a scintillator in a pressure vessel to obtain a mixed solution; and placing the pressure vessel in a liquid scintillation counter for carrying out radiocarbon activity detection.

Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.

Abstract: Embodiments of the present invention relate to mechanically-activated microcapsules (MAMCs) for controlled drug-delivery, wherein the MAMCs release one or more active ingredients in response to mechanical stimuli in a subject's body. The MAMCs provide a platform for stimulating biological regeneration, biological repair, modifying disease, and/or controlling disease in mechanically-loaded musculoskeletal tissues.

Abstract: Provided is a thrombin-carrying hemostatic sheet that is suitable for hemostasis during surgery, in particular, for hemostasis during spine surgery, that is convenient without preparation before use, and that is bioabsorbable and can be embedded in the body as it is. The hemostatic sheet is composed of a gelatin sponge carrying an effective amount of thrombin, wherein (A) the density is 30 to 55 mg/cm3, and (B) the shape maintaining angle in wet conditions is 55 to 120°.

Abstract: A method for in situ measurement of temperature at microwave-induced microscopic hot spots, temperature measuring particles and the device used are provided. For the temperature measurement demand of the microscopic hot spot of microwave field, loading fluorescent temperature measuring particles on the surface of solid particles, and the actual temperature of particles in micro scale can be measured by using its temperature sensitive fluorescence characteristics. The present disclosure builds a microwave field in-situ fluorescence test device to disperse the test particles loaded with fluorescent temperature measuring materials in the liquid solvent and place in the quartz sample tank in the microwave cavity, which can measure the actual temperature of the particles to be measured under microwave radiation.

Abstract: The present invention features an antibody mimetic, or an antigen binding fragment thereof, that specifically binds to an allosteric site of Aurora A kinase, therapeutic compositions comprising this antibody mimetic, and the use of the monobody to modulate Aurora A kinase for the treatment of cancer.

Abstract: A method of additively manufacturing a structure for use in a reactionary process includes forming a material from metal or metal oxide particles, a dispersion solvent, and a binder. The method also includes depositing the material onto a build platform and curing the material to form a structure for use in a reactionary process. The structure includes the metal or metal oxide particles and is configured to provide a reaction when exposed to a reactant.

Abstract: Methods of preparing nicotinamide riboside and derivatives thereof.

Abstract: In vitro and in vivo methods of removing carbon monoxide from hemoglobin in blood or animal tissue are described. Methods of treating carboxyhemoglobinemia (carbon monoxide poisoning) in a subject are also described. The methods include administering natural or artificial oxygen carriers that are in their reduced form. Methods of producing a reduced oxygen carrier are further described. Methods of treating cyanide poisoning or hydrogen sulfide poisoning with oxygen carriers are also described.

Abstract: The disclosure claims a method of stimulating a conditional quantum master equation in a quantum transport process by a recurrent neural network, comprising the following steps of: establishing a recurrent neural network which is a long short term memory network (LSTM), wherein the LSTM comprises TLSTM cells arranged in chronological order, and each LSTM cell has an input value xt and an output value ht, and there is a parameter (W, b) in the LSTM cell; replacing the input value xt with a shot noise spectrum S(?) of the current obtained according to the conditional quantum master equation; replacing the output value ht with a trace of density matrices in the conditional quantum master equation; and replacing the parameter (W, b) with a connection between density matrices in the conditional quantum master equation at imminent moments.

Abstract: Materials and methods for testing unknown substances for the presence of an opioid are described.

Abstract: The present disclosure relates to an antifungal composition including propylene glycol, caprylic acid, and carvacrol as active ingredients.

Abstract: Systems and methods presented herein include guest activity detection devices configured to detect activity of guests of an amusement park, and to send data indicative of the detected activity; an artificial intelligence entity management system configured to analyze the data indicative of the activity of the guests, and to modify properties of guest-specific artificial intelligence entities based at least in part on the analyzed data indicative of the activity of the guests; and park features disposed within a physical environment of the amusement park and configured to be instructed by the guest-specific artificial intelligence entities to modify a guest experience for the guests of the amusement park in accordance with the properties of the guest-specific artificial intelligence entities.

Abstract: Provided herein are compositions comprising multi domain peptide (MDP) hydrogels where the peptides that constitute the hydrogel have at least one N6-(1-iminoethyl)-lysine side chain. Also provided are hydrogels that further comprise a STING agonist, an immune checkpoint inhibitor, and/or an anti-cancer therapy. Also provided are methods of using such compositions in the treatment of cancer.