Abstract: The present invention includes a circuit-level system and method for preventing the propagation of soft errors in logic cells. A radiation jammer circuit in accordance with the present invention, including an RC differentiator and a depletion mode MOS circuit, when inserted at the output of a logic cell, significantly reduces the propagation of transient glitches. The radiation jammer circuit is a novel transistor-level optimization technique, which has been used to reduce soft errors in a logic circuit. A method to insert radiation jammer cells on selective nodes in a logic circuit for low overheads in terms of delay, power, and area is also introduced.
Abstract: The present invention relates to a method, system and software arrangement for determining the co-associations of allele types across consecutive loci and hence for reconstructing two haplotypes of a diploid individual from genotype data generated by mapping experiments with single molecules, families or populations. The haplotype reconstruction system, method and software arrangement of the present invention can utilize a procedure that is nearly linear in the number of polymorphic markers examined, and is therefore quicker, more accurate, and more efficient than other population-based approaches. The system, method, and software arrangement of the present invention may be useful to assist with the diagnosis and treatment of any disease, which has a genetic component.
Type:
Grant
Filed:
March 30, 2005
Date of Patent:
September 28, 2010
Assignees:
New York University, Wisconsin Alumni Research Foundation
Inventors:
Will Casey, Thomas Anantharaman, Bhubaneswar (Bud) Mishra
Abstract: Novel blood-brain barrier permeant amyloid-targeting peptides and peptide conjugates are described. The peptide conjugates include a radioisotope or other label in a stable complex that translocates across brain capillary endothelial cell monolayers. The labeled peptide conjugate binds to amyloid plaques (A?) associated with Alzheimer's disease, and is useful for the targeted delivery of therapeutic and diagnostic molecules into the brain.
Abstract: The invention relates to a system and method for visually representing the interactions of input variables and output variables using a visualization field. The method comprises generating a visualization field on a display device, generating input variable indicators representative of the input variables, positioning the input variable indicators relative to the visualization field, generating interaction indicators, which are indicators of the input variables, positioning the interaction indicators relative to the visualization field, and adjusting the appearance of the interaction indicators to reflect the values of the output variables. The interaction indicators may also comprise association indicators that identify the input variables associated with the interaction indicators.
Type:
Grant
Filed:
December 16, 2005
Date of Patent:
September 28, 2010
Assignee:
New York University
Inventors:
Dennis Shasha, Rodrigo Gutierrez, W. Bradford Paley, Christopher Poultney, Gloria Coruzzi
Abstract: This invention provides a recombinant nucleic acid which, when introduced in vivo into a mammalian cell endogenously expressing EB1, inhibits the expression of EB1 therein, thereby reducing the amount of stable microtubules in the cell. This invention further provides related compositions, nucleic acids, cells and methods.
Type:
Grant
Filed:
July 14, 2006
Date of Patent:
September 28, 2010
Assignee:
The Trustees of Columbia University in the City of New York
Abstract: A method for managing withdrawal from an addictive substance is described. The method involves administering one or more peptides having specific activity for the ? and/or ? isozyme of protein kinase C (PKC). The peptide(s) can be administered prior to, concurrent with, or subsequent to administration of the addictive substance. Also described is a kit having at least one container containing a peptide having isozyme-specific activity for ?PKC or ?PKC and instructions for use.
Type:
Grant
Filed:
May 22, 2007
Date of Patent:
September 28, 2010
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Daria Mochly-Rosen, Joan J. Kendig, Sarah M. Sweitzer
Abstract: The present invention discloses a method to deposit particles on a charge storage apparatus with charge patterns and a forming method for charge patterns. The forming method for charge patterns includes providing the charge storage apparatus having an electrically conducting substrate and a charge storage media layer. The charge storage apparatus is disposed in a vacuum or an anhydrous environment. An electrode and the electrically conducting substrate are utilized to conduct a first voltage and a second voltage respectively to form an electric field. Charges are then stored into the charge storage media layer of the charge storage apparatus through the electric field and the charge patterns are then formed. Accordingly, particles are deposited on the charge pattern-defined areas.
Abstract: The present invention provides methods of forming metal oxide semiconductor nanostructures and, in particular, zinc oxide (ZnO) semiconductor nanostructures, possessing high surface area, plant-like morphologies on a variety of substrates. Optoelectronic devices, such as photovoltaic cells, incorporating the nanostructures are also provided.
Type:
Grant
Filed:
April 2, 2007
Date of Patent:
September 28, 2010
Assignee:
The University of Utah Research Foundation
Abstract: Epitaxial gallium nitride is grown on a silicon substrate while reducing or suppressing the formation of a buffer layer. The gallium nitride may be grown directly on the silicon substrate, for example using domain epitaxy. Alternatively, less than one complete monolayer of silicon nitride may be formed between the silicon and the gallium nitride. Subsequent to formation of the gallium nitride, an interfacial layer of silicon nitride may be formed between the silicon and the gallium nitride.
Abstract: An excavation technique for a stratum capable of excavating a submerged stratum such as a layer containing an underground resource by using laser irradiation in liquid is provided. In this technique, a laser beam transmitted through laser transmission means 20 is irradiated in liquid 90 in form of a laser beam having a wavelength with high absorptance of the liquid 90 by laser-induced bubble generation means 35, generating a bubble flow 36, thus excavation of a submerged stratum may be carried out by using a laser-induced destruction effect. Moreover, a laser beam 41 having low absorptance of the liquid 90 is irradiated by laser irradiation means 39 and passed through the bubble flow 36, thereby applying a thermal effect to a stratum to destroy rock and excavate the stratum. The destruction effect and the thermal effect also may be cooperatively worked.
Type:
Grant
Filed:
March 16, 2006
Date of Patent:
September 28, 2010
Assignees:
Japan Drilling Co., Ltd., Tohoku University, National University Corporation the University of Electro-Communications
Abstract: A laser scattering based imaging technique is utilized in order to visualize the aerosol droplets in an inductively coupled plasma (ICP) torch from an aerosol source to the site of analytical measurements. The resulting snapshots provide key information about the spatial distribution of the aerosol introduced by direct and indirect injection devices: 1) a direct injection high efficiency nebulizer (DIHEN); 2) a large-bore DIHEN (LB-DIHEN); and 3) a PFA microflow nebulizer with a PFA Scott-type spray chamber. Moreover, particle image velocimetry (PIV) is used to study the in-situ behavior of the aerosol before interaction with, for example, plasma, while the individual surviving droplets are explored by particle tracking velocimetry (PTV). Further, the velocity distribution of the surviving droplets demonstrates the importance of the initial droplet velocities in complete desolvation of the aerosol for optimum analytical performance in ICP spectrometries.
Type:
Grant
Filed:
October 3, 2005
Date of Patent:
September 28, 2010
Assignee:
The George Washington University
Inventors:
Akbar Montaser, Kaveh Jorabchi, Kaveh Kahen
Abstract: The invention relates to methods and system for detecting ligand binding to membrane receptors and endocytosis. A method for detecting ligand binding to a membrane receptor includes the steps of: incubating the cell with a dye and a ligand; and detecting dye-containing endocytic vesicles in the cell. A system for screening ligand binding to membrane receptors includes an automatic liquid handling device; an x-y stage for positioning a plate; a microscope configured to image endocytic vesicles of a cell; a software for automatic analysis of FM spots (endocytic vesicles); and a control unit configured to control the movement of the x-y stage and the microscope.
Type:
Grant
Filed:
April 29, 2007
Date of Patent:
September 28, 2010
Assignees:
Shanghai Institutes for Biological Sciences, CAS, Peking University
Abstract: A method of growing group III-nitride crystals in a mixture of supercritical ammonia and nitrogen, and the group-III crystals grown by this method. The group III-nitride crystal is grown in a reaction vessel in supercritical ammonia using a source material or nutrient that is polycrystalline group III-nitride, amorphous group III-nitride, group-III metal or a mixture of the above, and a seed crystal that is a group-III nitride single crystal. In order to grow high-quality group III-nitride crystals, the crystallization temperature is set at 550° C. or higher. Theoretical calculations show that dissociation of NH3 at this temperature is significant. However, the dissociation of NH3 is avoided by adding extra N2 pressure after filling the reaction vessel with NH3.
Type:
Grant
Filed:
October 25, 2007
Date of Patent:
September 28, 2010
Assignee:
The Regents of the University of California
Abstract: The present invention is a yellow-green phosphor material with a high luminescence intensity. The present invention is suitable for excitation by ultraviolet or blue light. The phosphor material is made of a phosphate compound with a chemical formula of LiZn1-xPO4:Mx(0<x<0.2). The host lattice is LiZn1-xPO4 and the luminescent center is Mx, which is a transition metal element. The present invention is easily and fast fabricated for mass production and has a fine color purity and a good thermal stability.
Type:
Grant
Filed:
May 23, 2007
Date of Patent:
September 28, 2010
Assignee:
National Central University
Inventors:
Ru-Shi Liu, Ivan Baginskiy, Ting-Shan Chan, Jenq-Yang Chang
Abstract: A laryngeal stimulation system including a sensor for detecting an occurrence of a respiratory signal in a subject and a laryngeal stimulator adapted for coupling to a laryngeal muscle and operable to stimulate the laryngeal muscle in response to the sensor detecting the occurrence of the respiratory signal is provided. A method for laryngeal stimulation including detecting an occurrence of a respiratory signal in a subject and then stimulating a laryngeal muscle in response to detecting the occurrence of the respiratory signal is also provided.
Abstract: Methods and systems for tracking users and providing services are provided. The system comprises a plurality of pressure sensors, a storage unit, at least one service providing unit having a service, and a signal processing unit. The pressure sensors detect pressure applied thereon at a specific time point, and correspondingly generate sensed signals. The signal processing unit receives the sensed signals from the pressure sensors, and stores the sensed signals to the storage unit. The signal processing unit calculates a current state of an object according to the sensed signals and historical sensed signals and historical states of the object in the storage unit, and determines one of the at least one service providing unit according to the current state to activate service thereof.
Abstract: Novel human chemokine receptors, MCP-1RA and MCP-1RB, and processes for producing them are disclosed. The receptors, which are alternately spliced versions of MCP-1 receptor protein may be used in an assay to identify antagonists of MCP-1 which are therapeutically useful in the treatment of atherosclerosis and other diseases characterized by monocytic infiltrates.
Type:
Grant
Filed:
February 5, 2007
Date of Patent:
September 28, 2010
Assignee:
The Regents of the University of California
Abstract: The present invention provides a breast cancer resistance polynucleotide and protein of Macaca mulata (rhesus monkey) and uses thereof. The present invention also provides anti-BCRP antibodies and uses thereof, particularly as a hematopoietic stem cell marker.
Abstract: A markerless motion capture system is provided for measurements accurate enough for biomechanical, clinical, sport, entertainment, animation, game and movie, design, ergonomics, surveillance applications. The system has multiple cameras distributed around a viewing volume. The cameras allow for the creation of three-dimensional mesh representations of an object dynamically moving within the viewing volume. A model of the object that incorporates specific morphological and kinematic model information (including soft joint constraints) is then matched to the captured three-dimensional mesh representations. The matching routine aims to embed the model into each of the three-dimensional representations using (i) iterative closest point or simulated annealing algorithms and (ii) using soft joint constraints. This unique combination of routines offers a simple, time-efficient, accurate and thus more meaningful assessment of movements.
Type:
Grant
Filed:
March 9, 2007
Date of Patent:
September 28, 2010
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Lars Mündermann, Stefano Corazza, Thomas P. Andriacchi
Abstract: Methods and compositions are provided for the protection of normal cells from cytoreductive therapy that target proliferating cells, by administering an inhibitor of Wnt signaling pathways. Wnt signaling is critically important for homeostasis of the epithelial lining of the adult intestine and other proliferating normal adult tissues.
Type:
Grant
Filed:
February 16, 2007
Date of Patent:
September 28, 2010
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Mark Lee, Calvin Jay Kuo, Tannishtha Reya, Irving L. Weissman