Abstract: The present invention provides a microarray bioprobe device integrated with a semiconductor amplifier module, which integrates micro array biological probes and thin film transistors on a flexible substrate by Micro-Electro-Mechanical System (MEMS) processes and semiconductor processes. A signal from the microarray bioprobe device is amplified through a near amplifier to increase signal-to-noise ratio and impendence matching. The micro array biological probes of the present invention are produced on the flexible substrate such that the micro array biological probes can be disposed to conform to the profile of a living body's portion and improving contact between the probes and living body's portion.
Type:
Grant
Filed:
October 11, 2006
Date of Patent:
September 28, 2010
Assignee:
Chung Hua University
Inventors:
Jium Ming Lin, Li-Chern Pan, Po-Wei Lin
Abstract: The invention discloses the nanoparticles composed of chitosan, poly-?-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
Type:
Grant
Filed:
July 26, 2007
Date of Patent:
September 28, 2010
Assignees:
GP Medical, Inc., National Tsing Hua University
Inventors:
Hsing-Wen Sung, Yu-Hsin Lin, Hsiang-Fa Liang, Hosheng Tu
Abstract: The present invention relates to computing circuits and method for running an MPEG-2 AAC or MPEG-4 AAC algorithm efficiently, which is used as an audio compression algorithm in multi-channel high-quality audio systems, on programmable processors. In accordance with the present invention, the IMDCT process which takes large part of the amount of the operations in implementation of an MPEG-2/4 AAC algorithm can be performed in efficient. In addition, while the architecture of the existing digital signal processor is still used, the performance can be improved by means of the addition of the architecture of the address generator, Huffman decoder, and bit processing architecture. After all, to design and change the programmable processor is facilitated.
Type:
Grant
Filed:
January 30, 2006
Date of Patent:
September 28, 2010
Assignees:
Pulsus Technologies, Ajou University Industry-Academic Cooperation Foundation
Inventors:
Jong Hoon Oh, Myung Hoon Sunwoo, Jong Ha Moon
Abstract: Methods to minimize the impact of malicious peers on the performance of a peer-to-peer system. The system computes a global trust value for a peer by calculating the left principal eigenvector of a matrix of normalized local trust values, thus taking into consideration the entire system's history with each single peer. Algorithms for performing such computations in a scalable and distributed manner are provided. Rewarding highly reputable peers with better quality of service encourages non-malicious peers to share more information and to self-police their own information.
Type:
Grant
Filed:
November 15, 2004
Date of Patent:
September 28, 2010
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: The invention provides methods, compositions and kits for inducing and/or enhancing an immune response in a subject. The invention in some aspects includes polypeptide and nucleic acid molecules that induce and/or enhance an immune response. In some aspects of the invention, the polypeptide and/or nucleic acid molecules of the invention are useful to induce and/or enhance an immune response in a subject who has or is suspected of having cancer.
Type:
Grant
Filed:
September 9, 2004
Date of Patent:
September 28, 2010
Assignees:
Ludwig Institute for Cancer Research Ltd., Chancelors Masters and Scholars of the University of Oxford
Abstract: The transmitter of one embodiment of the present invention includes: a S/P section for converting original serial data to parallel data which will correspond to a plurality of subcarriers; and a second IFFT section for converting the parallel data from the frequency domain to the time domain. The transmitter includes, between the S/P section and the second IFFT section, a first IFFT section for modulating the plurality of subcarriers using elements of a matrix derived from an expression for Inverse Discrete Fourier Transform involving time domain signal levels and frequency domain signal levels. The configuration enables CI and PO-CI to be implemented on transmitters and receivers with a simple configuration.
Type:
Grant
Filed:
August 1, 2006
Date of Patent:
September 28, 2010
Assignees:
National University Corporation Nara Institute of Science and Technology, Sky Perfect JSAT Corporation
Abstract: In one embodiment, there is disclosed a method of inducing an immune response in a subject comprising administering to the subject a Francisella bacterium that includes an alteration in the nucleic acid sequence encoding the mglA, iglA, iglB, iglC, or iglD gene of the bacterium.
Type:
Grant
Filed:
February 28, 2007
Date of Patent:
September 28, 2010
Assignee:
The Board of Regents of the University of Texas System
Abstract: Crystalline silicon particles of nanometer order usable as a semiconductor element are provided by a method for producing SiOx particles, comprising irradiating SiOx (X is 0.5 or more and less than 2.0) particles each including therein an amorphous silicon particle having a particle diameter of 0.5 to 5 nm with light, and preferably a laser beam, to produce SiOx (X is 0.5 or more and less than 2.0) particles each including therein a crystalline silicon particle having a particle diameter of 1 to 10 nm.
Type:
Grant
Filed:
September 22, 2005
Date of Patent:
September 28, 2010
Assignees:
The University of Electro-Communications, Denki Kagaku Kogyo Kabushiki Kaisha
Abstract: A DNA Polymerase has been identified in a thermophile that functions as a chromosomal replicase. The specific enzyme is a holoenzyme III that has been identified in Thermus thermophilus, and corresponds to Polymerase III in E. coli. The genes and the polypeptides corresponding to T.th. ?, ?, ?, ? and ? subunits that they encode are disclosed, as are probes, vectors, methods of preparation and the methods of use. The enzymes of the present invention and their components are particularly well suited for use in procedures for the preparation of DNA, such as PCR, because of the speed and accuracy that they are able to achieve.
Type:
Grant
Filed:
June 4, 2009
Date of Patent:
September 28, 2010
Assignee:
The Rockefeller University
Inventors:
Olga Yurieva, John Kuriyan, Michael E. O'Donnell, David Jeruzalmi
Abstract: An ultrasound based technique for detecting and imaging vibrations in tissue caused by eddies produced during bleeding through punctured arteries or from organs. A clutter signal, normally suppressed in conventional color flow imaging, is employed to detect and characterize local tissue vibrations, to detect internal bleeding in an image, or as an audible or palpable signal, or a readout. Using a tissue vibration image, the origin and extent of vibrations relative to the underlying anatomy and blood flow can be visualized in real time, enabling measurements of vibration amplitude, frequency, and spatial distribution. Bleeding rate can be determined from the frequency and amplitude of the vibrations. Signal processing algorithms usable to identify tissue vibrations from an ensemble of 2D ultrasound data include those based on phase decomposition, spectral estimation using eigendecomposition, and spectral estimation using autoregressive modeling for isolating vibrations from clutter, blood flow, and noise.
Type:
Grant
Filed:
October 1, 2004
Date of Patent:
September 28, 2010
Assignee:
University of Washington through its Center for Commericalization
Inventors:
Siddhartha Sikdar, Yongmin Kim, Kirk Beach
Abstract: Disclosed herein is an attitude correction apparatus for an Inertial Navigation System (INS) using a camera-type solar sensor. The present invention relates to a system for correcting errors occurring in an inertial navigation system, in which inertial sensors, such as gyroscopes and accelerometers are combined with each other to calculate the attitude, velocity and position of an airplane, and to an apparatus for utilizing a sun-line of sight vector, generated by a camera-type solar sensor, that uses images of the moving sun, and the output value of the inertial navigation system, thus correcting the attitude of an airplane and the errors of sensors. The attitude correction apparatus of the present invention includes a camera-type solar sensor for detecting the sun, a signal processing unit for receiving and synchronizing information, and a data collection processing unit for performing post-processing on information, thus correcting an error.
Type:
Grant
Filed:
May 1, 2007
Date of Patent:
September 28, 2010
Assignee:
INHA University
Inventors:
Choon Bae Park, Kee Young Choi, Se Ah Jang
Abstract: A method for fabricating a composite material includes providing a free-standing carbon nanotube structure having a plurality of carbon nanotubes, introducing at least two reacting materials into the carbon nanotube structure to form a reacting layer, activating the reacting materials to grow a plurality of nanoparticles, wherein the nanoparticles are spaced from each other and coated on a surface of each of the carbon nanotubes of the carbon nanotube structure.
Type:
Application
Filed:
November 25, 2009
Publication date:
September 23, 2010
Applicants:
Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
Inventors:
Jia-Ping Wang, Kai-Li Jiang, Qun-Qing Li, Shou-Shan Fan
Abstract: A motion compensation apparatus for a camera module with a half-shutter function is provided. The apparatus includes an initialization unit for selecting a subject, a motion of which is to be detected, from images secured in a half-shutter state, and calculates motion information of the subject; a tracking unit for tracking the selected subject and the motion information provided from the initialization unit, and calculates prediction information of the subject; and a controller for generating a control signal for controlling a speed of a shutter and a sensibility of an image sensor based on the prediction information provided from the tracking unit.
Type:
Application
Filed:
March 19, 2010
Publication date:
September 23, 2010
Applicants:
Samsung Electronics Co., Ltd., University-Industry Cooperation Group of Kyung Hee University
Abstract: A method for producing glucosamine with microorganism comprises of fermenting with a microorganism selected from the group consisting of Monascus pilosus and Aspergillus sp. in a novel low-cost medium, thereby enable it to produce glucosamine; wherein said medium is consisted of commercial Taiwan sugar, soy beam, rice bran and the like; wherein suitable condition for the fermentation is: 150˜300 rpm, pH 4˜pH 8, and 24° C.˜37° C.; wherein, after fermentation culturing, the fermentation liquor is filtered with suction to recover said microorganism biomass, said microorganism biomass is then subjected to steps of cell disruption, hydrochloric acid reaction, neutralization reaction and filtration, to obtain glucosamine produced by the microorganism.
Abstract: Methods for treating and/or preventing skin ulcers are provided featuring administration of pharmaceutical compositions comprising inhibitors of activity or expression Of Lp-PLA2 protein to patients subject to or at risk of developing skin ulcers.
Type:
Application
Filed:
May 9, 2008
Publication date:
September 23, 2010
Applicant:
The Trustees of the University of Pennsylvania
Inventors:
Robert Wilensky, Damir Hamamdzic, Harrilla Profka
Abstract: The methods and apparatus of the present invention allow the evaluation of inflammation of the esophagus. Measurements may be utilized, for example, to diagnose a disease of the esophagus, to monitor inflammation of the esophagus, or to access the treatment of a disease of the esophagus. In one embodiment, the invention comprises a method for measuring esophageal inflammation comprising deploying a device into the esophagus of a subject, removing the device after a predetermined period of time, analyzing the device for a diagnostic indicator of esophageal inflammation and evaluating the diagnostic indicator to diagnose esophageal inflammation.
Type:
Application
Filed:
November 5, 2008
Publication date:
September 23, 2010
Applicants:
The Regents of The University of Colorado, A Body Corporate, The Board of Trustees of The University of Illnois
Abstract: The disclosure related to a composite material. The composite material includes a free-standing carbon nanotube structure having a plurality of carbon nanotubes and a number of nanoparticles. The nanoparticles are spaced from each other and coated on a surface of each of the carbon nanotubes of the carbon nanotube structure.
Type:
Application
Filed:
October 23, 2009
Publication date:
September 23, 2010
Applicants:
Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
Inventors:
Jia-Ping Wang, Kai-Li Jiang, Qun-Qing Li, Shou-Shan Fan
Abstract: The invention provides compounds of formula I: wherein A, B, W, Y, Z, and R1 have any of the meanings defined in the specification and their pharmaceutically acceptable salts. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula I, intermediates useful for preparing compounds of formula I, and therapeutic methods for treating cancer using compounds of formula I.
Type:
Application
Filed:
May 28, 2010
Publication date:
September 23, 2010
Applicant:
Rutgers, the State University of New Jersey
Inventors:
Edmond J. LaVoie, Alexander L. Ruchelman