Abstract: This invention provides a polyfunctional polymer having high stereoregularity, in particular, isotacticity, and provides a production process thereof. The present invention relates to a polymer having, in a molecule, a repeating unit represented by General Formula (2): wherein R1 and R2 are different, and each represents a hydrogen atom, an alkyl group and an aryl group; * represents an asymmetrical carbon, the polymer containing meso diad (m) and racemo diad (r) at a proportion of 60:40 to 100:0 (m:r). The invention also relates to chemical modifications and a production process of the polymer.
Abstract: A composition for use in an electrochemical cell is disclosed wherein the composition includes a clean metal substantially free of impurities and a layer of protective material in contact with the clean metal. Further disclosed is an electrochemical cell including a metal film comprising a clean metal substantially free of impurities. The electrochemical cell may further include an electrolyte and a layer of protective material disposed between the electrolyte and the metal film. A process for manufacturing an electrode is further disclosed including preparing a metal film comprising a clean metal substantially free of impurities and depositing a layer of protective material on to the metal film.
Type:
Grant
Filed:
February 27, 2009
Date of Patent:
April 22, 2014
Assignees:
Toyota Motor Engineering & Manufacturing North America, Inc., The Regents of the University of California
Inventors:
Erik Menke, Grant Umeda, Brittnee Veldman, Bruce Dunn, Fred Wudl, Monique Nathalie Richard, Kimber Lee Stamm
Abstract: This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the ?641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease.
Type:
Grant
Filed:
March 15, 2013
Date of Patent:
April 22, 2014
Assignee:
Albert Einstein College of Medicine of Yeshiva University
Abstract: A membrane electrode assembly (MEA) for a fuel cell comprising a gradient catalyst structure and a method of making the same. The gradient catalyst structure can include a plurality of catalyst nanoparticles, e.g., platinum, disposed on layered buckypaper. The layered buckypaper can include at least a first layer and a second layer and the first layer can have a lower porosity compared to the second layer. The gradient catalyst structure can include single-wall nanotubes, carbon nanofibers, or both in the first layer of the layered buckypaper and can include carbon nanofibers in the second layer of the layered buckypaper. The MEA can have a catalyst utilization efficiency of at least 0.35 gcat/kW or less.
Type:
Grant
Filed:
July 19, 2010
Date of Patent:
April 22, 2014
Assignee:
Florida State University Research Foundation, Inc.
Inventors:
Chun Zhang, Wei Zhu, Jian-ping Zheng, Zhiyong Liang, Ben Wang
Abstract: A translation between a source language and a target language is disclosed. The source language items are divided, with primary and secondary source language items or named entities being identified, where the primary and secondary source languages being different from each other and from the target language. The entities in the second source language are translated in a different way. For example, they may be copied into the target language, or translated in a special way that is based on their meaning, e.g, into a term that has a more descriptive meaning in the target language.
Abstract: Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
Type:
Grant
Filed:
February 8, 2010
Date of Patent:
April 22, 2014
Assignee:
The University of Chicago
Inventors:
Robert Kisilevsky, Shui-Pang Tam, John B. Ancsin, Zongchao Jia
Abstract: In one aspect, the invention relates to substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the BTK kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the BTK kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Type:
Grant
Filed:
April 1, 2012
Date of Patent:
April 22, 2014
Assignee:
University of Utah Research Foundation
Inventors:
David J. Bearss, Hariprasad Vankayalapati, Venkataswamy Sorna, Steven L. Warner, Sunil Sharma
Abstract: A reinforced composite material includes a solid polymer matrix, a reinforcing material in the solid polymer matrix, and a first plurality of capsules. The reinforcing material includes a surface. The capsules are on the surface of the reinforcing material, and include a liquid healing agent. The amount of the healing agent of the capsules is at least 0.01 milligrams per square centimeter of the surface area of the reinforcing material.
Type:
Grant
Filed:
August 18, 2009
Date of Patent:
April 22, 2014
Assignee:
The Board of Trustees of the University of Illinois
Inventors:
Benjamin J. Blaiszik, Jericho L. Moll, Brett A. Beiermann, Scott R. White, Nancy R. Sottos
Abstract: A clock mesh network synthesis method is proposed which enables clock gating on the local sub-trees of the clock mesh network in order to reduce the clock power dissipation. Clock gating is performed with a register clustering strategy that considers both i) the similarity of switching activities between registers in a local area and ii) the timing slack on every local data path of the design area. The method encapsulates the efficient implementation of the gated local trees and activity driven register clustering with timing slack awareness for clock mesh synthesis. With gated local tree and activity driven register clustering, the switching capacitance on the mesh network can be reduced by 22% with limited skew degradation. The method has two synthesis modes as low power mode and high performance mode to serve different design purposes.
Abstract: A system for analyzing a liquid is provided. The system comprises: an electrochemical unit having an electrochemical microchamber for receiving a sample of the liquid and electrochemically analyzing the sample; and a microfluidic unit being attached to the electrochemical unit and having microchannels constituted for sampling the sample in situ and feeding the sample to the electrochemical microchamber. Also provided are nucleic acid constructs and cells comprising same for analyte detection.
Type:
Grant
Filed:
December 30, 2010
Date of Patent:
April 22, 2014
Assignees:
Ramot at Tel-Aviv University Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
Inventors:
Yosi Shacham-Diamand, Hadar Ben-Yoav, Shimshon Belkin, Rami Pedahzur, Alva Biran, Georg Reifferscheid, Sebastian Buchinger
Abstract: A method for treating organophosphorous poisoning (OP) comprising administering to a mammal at risk for OP poisoning an OP poisoning-inhibiting amount of galantamine.
Type:
Grant
Filed:
February 14, 2011
Date of Patent:
April 22, 2014
Assignees:
University of Maryland Baltimore, The United States of America as repr. by the Sec. of the Army, U.S. Army Med. Resr. Inst. of Chem. Defense
Inventors:
Edson X. Albuquerque, Michael Adler, Edna F.R. Pereira
Abstract: Provided are peptides or mimetics that block corepressor binding to a BCL6 lateral groove. Also provided are methods or blocking corepressor binding to the BCL6 lateral groove. Additionally, methods of inhibiting BCL6 repression in a mammalian cell, and methods of treating a mammal with cancer are provided.
Type:
Grant
Filed:
February 23, 2011
Date of Patent:
April 22, 2014
Assignees:
Albert Einstein School of Medicine of Yeshiva University, Mount Sinai School of Medicine
Abstract: Heat-transfer fluids and lubricating fluids comprising deaggregated diamond nanoparticles are described herein. Also described are composites comprising deaggregated diamond nanoparticles, and methods of making such composites. Method of using deaggregated diamond nanoparticles, for example, to improve the properties of materials such as thermal conductivity and lubricity are also disclosed.
Type:
Grant
Filed:
January 12, 2011
Date of Patent:
April 22, 2014
Assignee:
Vanderbilt University
Inventors:
Blake T. Branson, Charles M. Lukehart, Jim L. Davidson
Abstract: The present disclosure relates to hydrolysis of hexose-?-lactones by use of an S. thermophile extracellular aldonolactonase. In particular the present disclosure relates to compositions including a S. thermophile extracellular aldonolactonase and methods of use thereof.
Type:
Grant
Filed:
October 10, 2013
Date of Patent:
April 22, 2014
Assignee:
The Regents of the University of California
Inventors:
William T. Beeson, IV, James H. Dounda Cate, Michael A. Marletta
Abstract: Disclosed are newborn infant formulas comprising fat, carbohydrate, and from 0.5 to 2.5 g of protein per 100 ml of formula, wherein the formula has a caloric density of from 25 to 50 kcal per 100 ml of formula. Also disclosed are methods of administering the infant formulas to provide newborns with optimal nutrition, to reduce the occurrence or extent of insulin resistance in an individual later in life, to reduce the occurrence or extent of atherosclerosis or coronary artery disease in an individual later in life, or combinations thereof, by feeding newborn infants the newborn infant formula described herein.
Abstract: A novel yellow phosphor of a fluorosulfide having a chemical formula of (A1-x-yCexBy)2Ca1-zSrzF4S2 and a tetragonal crystal phase is disclosed, wherein A and B are different rare earth metals other than Ce, the values of x, y, z are 0<x?1, 0?y?1, and 0?z?1, respectively. A preparation method of the fluorosulfide and white-light emitting diode application thereof are also disclosed.
Abstract: A device (10) for receiving implanted biological material includes a mechanoprotective surface (16) defining an adjacent space, an assembly (26, 28) for locally delivering media to said space, and a pump or slow/sustained release reservoir structure (14) operatively coupled to the assembly. The device may comprise an additional plunger body for being disposed in said space. The implanted biological material may be encapsulated or non-encapsulated.
Type:
Grant
Filed:
February 1, 2008
Date of Patent:
April 22, 2014
Assignees:
University of Miami, Converge Biotech Inc.
Inventors:
Nicholas Bodor, Peter Buchwald, Christopher A. Fraker, Jeffrey Hubbell, Luca Inverardi, Norma Sue Kenyon, Paul Latta, Antonello Pileggi, Cheryl Stabler Anderson, Fabio Grassi, Camillo Ricordi
Abstract: A method and a multichannel implantable device are described for partial or complete restoration of impaired gastrointestinal motility, or for disturbing and/or partially or completely blocking normal gastrointestinal motility using one or multiple microsystem-controlled channels of circumferentially arranged sets of two or more electrodes which provide externally-invoked synchronized electrical signals to the smooth muscles via the neural pathways.
Type:
Grant
Filed:
February 15, 2008
Date of Patent:
April 22, 2014
Assignee:
University Technologies International Inc.
Abstract: A groundwater sampling tool that includes an elongated hollow coring tube having a proximal end and a distal end for collecting groundwater and sediment; a Peltier element located in close proximity to a wall of the elongated hollow coring tube adapted to freeze groundwater and sediment collected by the elongated hollow coring tube.
Type:
Grant
Filed:
August 16, 2011
Date of Patent:
April 22, 2014
Assignee:
The Trustees of Columbia University in the City of New York
Inventors:
Alexander van Geen, Benjamin Bostick, Christopher Manning
Abstract: Systems, methods, and computer readable storage media are described that can provide a multi-level hierarchical framework to progressively associate detection responses, in which different methods and models are adopted to improve tracking robustness. A modified transition matrix for the Hungarian algorithm can be used to solve the association problem that considers not only initialization, termination and transition of tracklets but also false alarm hypotheses. A Bayesian inference approach can be used to automatically estimate a scene structure model as the high-level knowledge for the long-range trajectory association.