Abstract: The present disclosure provides optionally substituted seven-membered ring isomers of naturally occurring carbohydrate compounds, methods of synthesizing these compounds, intermediate compounds, methods of synthesizing the intermediate compounds, and the like.

Abstract: A contour mode micromechanical piezoelectric resonator. The resonator has a bottom electrode; a top electrode; and a piezoelectric layer disposed between the bottom electrode and the top electrode. The piezoelectric resonator has a planar surface with a cantilevered periphery, dimensioned to undergo in-plane lateral displacement at the periphery. The resonator also includes means for applying an alternating electric field across the thickness of the piezoelectric resonator. The electric field is configured to cause the resonator to have a contour mode in-plane lateral displacement that is substantially in the plane of the planar surface of the resonator, wherein the fundamental frequency for the displacement of the piezoelectric resonator is set in part lithographically by the planar dimension of the bottom electrode, the top electrode or the piezoelectric layer.

Abstract: An evaluation device is configured to provide a transceiver system with performance information thereof. The transceiver system models a channel between a transmitter and a receiver thereof using Nakagami distribution with a fading parameter. The evaluation device includes a setting module operable to set an average signal-to-noise rate (SNR) for the channel between the transmitter and the receiver, a computing module operable to estimate a symbol error rate related to a signal received by the receiver from the transmitter based upon the fading parameter and the average SNR, and an output module operable to provide the average SNR and the symbol error rate as the performance information of the transceiver system.

Abstract: Disclosed is an apparatus and method for generating a real-time stereoscopic image from depth map. According to the depth information of the image, a depth-image-based rendering (DIBR) algorithm is used to shift (or move) the position of the object in the image to generate the stereoscopic image with parallax. When the object is shifted (or moved) away from its original position, a hole will occur in the original position. Therefore an image inpainting algorithm is developed to fill the hole. In order to achieve the real-time application, a hardware architecture and method have been developed to accomplish the DIBR and image inpainting algorithm.

Abstract: The invention relates to Nucleobindin-1 (NUCB1) protein variants that are capable of disaggregating amyloid fibrils as well as inhibiting the formation of fibrils in the presence of physiological concentrations of calcium. Isolated NUCB1 protein variants, nucleic acids encoding the protein variants, cells comprising the isolated nucleic acids, pharmaceutical compositions and kits comprising the variants, methods of making the variants, and therapeutic uses of the variants are provided.

Abstract: A blood coagulation detection device includes a micro channel unit, an optical signal unit, an opto-electronic conversion circuit, an amplifier circuit, and a filter circuit. The micro channel unit has a sample detection area. The optical signal unit transmits a reference light to the micro channel unit so as to form a message light. The opto-electronic conversion circuit receives the message light and converts the message light into an electrical signal. The amplifier circuit is electrically connected to the opto-electronic conversion circuit for amplifying the electrical signal. The filter circuit is electrically connected to the amplifier circuit for filtering the amplified electrical signal.

Abstract: Methods, systems, and apparatus are provided for determining whether a nucleic acid sequence imbalance exists within a biological sample. One or more cutoff values for determining an imbalance of, for example, the ratio of the two sequences (or sets of sequences) are chosen. The cutoff value may be determined based at least in part on the percentage of fetal DNA in a sample, such as maternal plasma, containing a background of maternal nucleic acid sequences. The cutoff value may also be determined based on an average concentration of a sequence per reaction. In one aspect, the cutoff value is determined from a proportion of informative wells that are estimated to contain a particular nucleic acid sequence, where the proportion is determined based on the above-mentioned percentage and/or average concentration. The cutoff value may be determined using many different types of methods, such as sequential probability ratio testing (SPRT).

Abstract: Bioresorbable scaffolds for bone engineering, such as repair of bone defects, particularly long bone defects, or augmentation of bone length are described. Scaffolds are porous and comprise multiple side channels. In one embodiment, scaffolds are made from layers of micro-filament meshes comprising polycaprolactone (PCL) or a PCL-composite sequentially laid in incremental 60 degrees of rotation to produce a 0/60/120 degree layering pattern, providing for the formation of interconnected pores. The scaffold can comprise a central channel filled, packed or infused with suitable agents such as bioactive agents. Furthermore, the scaffolds are stiff but yet fracture resistant and with sufficient bending, compressive and torsional strength suitable for bone engineering. The slow degradation of the scaffold is sufficient for the 3D matrix to maintain structure integrity and mechanical properties during the remodelling process.

Abstract: Immobilized nitronyl nitroxide active sites on the surface of a porous inorganic oxide support act as efficient and rapid oxidants for NO, reacting with >99% of the NO under flow conditions through a packed bed; and, in a parallel configuration with nitroxyl radical active sites, act to remove >99 % of both NO and NO2 from a gas mixture, with >95% of the active sites participating in NOx trapping.

Abstract: A biocompatible insulin delivery device is provided comprising an insulin reservoir sealed with a glucose-responsive plug or membrane. The plug functions to release insulin from the reservoir in response to a hyperglycemic glucose concentration and to prevent insulin release from the reservoir in response to hypoglycemic glucose concentration. In one embodiment, the plug is made of a biocompatible polymeric matrix comprising an inorganic component, a stimulus-responsive component and a catalytic component.

Abstract: Methods, devices, and systems for separating a time-varying flow of disparate liquid-suspended particles through a channel using dielectrophoresis and field-flow fractionation.

Abstract: The present invention generally relates to implantable devices for producing insulin in diabetic animals and to methods of making same. Some embodiments include amphiphilic biomembranes for use in biological applications (e.g., as an alternative and/or supplemental insulin source). Some embodiments also include live insulin-producing cells contained within one or more amphiphilic membranes so as to prevent or diminish an immuno-response and/or rejection by the host.

Abstract: The structural material with embedded sensors provides of diagnostics and measurement of static and/or dynamic strains in structures and structural elements formed from the structural material. The structural material includes an array of fiber Bragg grating sensors or the like embedded therein for strain measurement and monitoring. An array of linear channels is formed in the structural element, and the plurality of fiber Bragg grating sensors are respectively disposed therein. The plurality of fiber Bragg grating sensors communicate with a signal analyzer, which receives the signals generated by the fiber Bragg grating sensors, the signals being representative of a magnitude of a strain placed on the structural element. The signal analyzer may, in turn, transmit a conditioned signal to a computer or the like for presentation of strain data to the user.

Abstract: In one embodiment, a system and a method for identifying the class of a component of a mixture includes collecting samples from a sample source, determining a summed ion spectrum for each sample and generating sample data from the summed ion spectra, comparing the sample data with reference summed ion spectra of multiple reference substances to determine correlations between the reference substances and the sample data, and evaluating the correlations of the substances of each substance class to determine which substance class most closely correlates to the sample data.

Abstract: A method for protecting against link failures in a communications network having a plurality of paths between senders and receivers is provided. The method includes sending data units by the senders over the communications network on working circuits, applying network coding to form a combination of data units from data units from a plurality of the senders, and sending the combination of data units over the communications network on a backup circuit. If one or more link failures occur in the working circuits resulting in loss of one or more of the data units, then the method further includes recovering the one or more of the data units from the combination of data units transmitted on the backup circuit. The backup circuit used to carry the combination of data units may be implemented in-band with user data or may be implemented as out-of-band backup circuits.

Abstract: Electrode active material that is used together with an electrolyte solution having an electrolyte decomposition potential Ve is represented by the general expression LixFeMyO2 and is amorphous. In the expression, x and y are values which independently satisfy 1<x?2.5 and O<y?3, respectively, and z=(x+(valence of Fe)+(valence of M)×y)/2 to satisfy stoichiometry, and M represents one or two or more types of glass former element. The average electronegativity of M is less than (Ve+6.74/5.41.

Abstract: An apparatus and method for holding a membrane, screen or other flexible planar body in tension, while providing a conduit for water or other liquid to flow to the membrane being held. The membrane extends from inside a manifold body that carries the liquid, and the manifold body supports the membrane at one edge while the membrane is pulled in tension. Liquid pressure builds up inside the manifold body, preferably by entering a pressure chamber at the top of the manifold body. At a feeding pressure in the pressure chamber the liquid is distributed to the membrane for microbe growth. The liquid can be elevated to a higher, microbe-harvesting pressure by increasing the pressure in the pressure chamber, thereby deflecting a shim separating the pressure chamber from the membrane. The change in pressure is carried out by manually or automatically opening and closing a conventional water valve.

Abstract: The present application provides fully human antibodies against N-Cadherin for therapeutic and diagnostic methods in cancer.

Abstract: The subject invention pertains to methods and compositions for protecting feline animals from infection by FIV using immunogens derived from primate immunodeficiency viruses, including HIV and SIV. Methods for vaccinating feline animals with the subject vaccine compositions are described. Feline animals vaccinated according to the methods and compositions of the subject invention exhibit protective humoral and cellular immune responses to FIV when challenged with FIV.

Abstract: A signal processing device and an image processing device are provided. The signal processing device includes a matrix calculator for performing a matrix operation selected by a switch part among a DCT matrix operation, a Haar matrix operation, and a Slant matrix operation, with respect to an input signal. Thus, the signal processing device can be implemented in a hybrid architecture capable of selectively processing the DCT-II transform, the Haar transform, and the Slant transform with a single chip.