Patents Assigned to University
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Patent number: 12243290Abstract: A method, apparatus, and system for detecting DeepFake videos, includes an input device for inputting a potential DeepFake video, the input device inputs a sequence of video frames of the video, and processing circuitry. The processing circuitry detects faces frame by frame in the video to obtain consecutive face images, creates UV texture maps from the face images, inputs both face images and corresponding UV texture maps, extracts image feature maps, by a convolution neural network (CNN) backbone, from the input face images and corresponding UV texture maps and forms an input data structure, receives the input data structure, by a video transformer model that includes multiple encoders, and computes, by the video transformer model, a classification of the video as being Real or Fake. A display device plays back the potential DeepFake video and an indication that the video is Real or Fake.Type: GrantFiled: June 8, 2022Date of Patent: March 4, 2025Assignee: Mohamed bin Zayed University of Artificial IntelligenceInventors: Sohail Ahmed Khan, Hang Dai
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Patent number: 12240821Abstract: The invention provides a series of GMPS enzyme inhibitors. The invention includes potent GMPS inhibitors that specifically and covalently bind to GMPS, exhibit broad anti-cancer activity, block the infection efficiency of viruses, and have the potentials to suppress undesired immune responses. These novel inhibitors of GMPS, and their derivatives, have tremendous potentials to be used as therapeutic agents for the treatment of cancers, viral infection and immune disorders.Type: GrantFiled: July 12, 2019Date of Patent: March 4, 2025Assignee: University of Southern CaliforniaInventors: Chao Zhang, Feng Ni, Arunika Ekanayake, Biancha Espinosa
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Patent number: 12244151Abstract: A system includes a body comprising a conduction path, and first and second modules disposed along, and movable relative to, the body, each of the first and second modules including an energy storage device, a terminal, and a power management unit coupling the energy storage device and the terminal. The terminal of each of the first and second modules is capacitively coupled with the conduction path for bidirectional power transfer between the first and second modules via the conduction path.Type: GrantFiled: March 11, 2021Date of Patent: March 4, 2025Assignee: The Regents of the University of MichiganInventors: Al-Thaddeus Avestruz, Akshay Sarin, Shai Revzen, Duncan Abbot
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Patent number: 12243004Abstract: An automated inventory monitoring system includes an image capture module able to create an image of an aisle of a retail store. Product images and shelf label and peg label images are identified in the image and products are associated with product labels based on the positioning of the products with respect to the labels. Based on the association between labels and products, out-of-stock products are detected and reported to the retail store.Type: GrantFiled: April 13, 2020Date of Patent: March 4, 2025Assignee: Carnegie Mellon UniversityInventors: Sarjoun Skaff, Marios Savvides, Uzair Ahmed, Nikhil Mohan, Sreena Nallamothu
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Patent number: 12239328Abstract: The device of the present disclosure is configured for laparoscopic use, particularly to insert a fastener into a plate at an angle of up to 180° from the plane of insertion. The device is further configured to carry a plurality of fasteners, a tightening tool, a cutting device, and tweezers simultaneously to facilitate a rapid procedure while lessening the chance of infection by limiting the amount of times the device must be removed and re-inserted.Type: GrantFiled: April 23, 2021Date of Patent: March 4, 2025Assignees: The Trustees of Indiana University, Purdue Research FoundationInventors: Peter Clifton Jenkins, Ramses Martinez
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Patent number: 12242416Abstract: A systolic neural CPU (SNCPU) including a two-dimensional systolic array of reconfigurable processing elements (PE's) fuses a conventional CPU with a convolutional neural network (CNN) accelerator in four phases of operation: row-CPU, column-accelerator, column-CPU, and row-accelerator. The SNCPU cycles through the four phases to avoid costly data movement across cores, reduce overhead, and reduce latency. The PE's communicate bidirectionally with neighboring PE's and memory units at an outer edge of the array. A row of PE's is configurable into a first deep neural network (DNN) accumulator at a first time and configurable into a first CPU pipeline at a second time. A column of PE's is configurable into a second DNN accumulator at a third time and configurable into a second CPU pipeline at a fourth time.Type: GrantFiled: December 23, 2022Date of Patent: March 4, 2025Assignee: Northwestern UniversityInventors: Jie Gu, Yuhao Ju
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Patent number: 12240810Abstract: Chiral polyvinylpyrrolidinone (CSPVP), complexes of CSPVP with a core species, such as a bimetallic nanocluster catalyst, and enantioselective oxidation reactions utilizing such complexes are disclosed. The catalytic complexes have exhibited the ability to achieve reaction products have a very high degree of optical purifies. These reaction products can be used as reagents in the synthesis of complex organic molecules, such as bioactive products, and C—H bond oxidation of complex molecules including various drugs and natural products.Type: GrantFiled: February 4, 2020Date of Patent: March 4, 2025Assignee: Kansas State University ResearchInventor: Duy H. Hua
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Patent number: 12244000Abstract: A method of producing a cathode material for a lithium-ion battery includes combining an electrode precursor material and humic acid in an alkaline slurry, drying the alkaline slurry to produce a powder of humic acid-coated electrode precursor material, and heating the powder to produce the electrode material comprising graphene-coated particles.Type: GrantFiled: December 21, 2021Date of Patent: March 4, 2025Assignee: University of North DakotaInventor: Xiaodong Hou
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Patent number: 12240787Abstract: A preparation method for improving light efficiency and stability of light storing ceramics is provided. Calcium ethanol solution is added into titanium precursor solution firstly and oleic acid dispersant is added, pure water and the light storing powder are subsequently added to obtain a light-storing powder-calcium titanate gel, and dried, crushed and sieved to obtain xerogel powder. Glass matrix material, sieved xerogel powder and another dispersant are placed into a granulator, and directly mechanically stirred and granulated after adding pure water. A plasticizer is added after stirring 4˜8 h, and continuously stirred for 1˜3 h to obtain a mixture, pressing, drying and firing. Calcium titanate is manually introduced to protect the light-storing powder from hydrolysis or high-temperature oxidation. It can also change the propagation path of fluorescence inside ceramics, improve light absorption and fluorescence output efficiency and is conducive to ceramic molding.Type: GrantFiled: December 1, 2021Date of Patent: March 4, 2025Assignees: Jiangsu Normal University, Xuzhou All-To Photoelectric Technology Co., LTDInventors: Le Zhang, Shunshun Yang, Rui Wang, Tao Li, Xiaowen Zhu, Xinyu Jiang, Guocan Huang, Jian Kang, Bingheng Sun, Cen Shao, Tianyuan Zhou, Hao Chen
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Patent number: 12239785Abstract: A ventilation system having a mask, a blowing assembly, and a processor. The mask has a mask body and a pressure sensor operatively associated with the mask body and configured to measure pressure within the mask. The mask body defines an inlet opening and a plurality of leak openings. The blowing assembly is positioned in fluid communication with the inlet opening of the mask body and configured to direct air to the inlet opening of the mask body. The processor is positioned in operative communication with the blowing assembly and the pressure sensor of the mask. The processor is configured to selectively control the blowing assembly based upon at least the measured pressure within the mask.Type: GrantFiled: August 18, 2021Date of Patent: March 4, 2025Assignee: University of Utah Research FoundationInventors: Michael Fogarty, Joseph Orr, Kai Kuck
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Patent number: 12241114Abstract: In one aspect, the present invention provides a method of selecting or identifying an agent that inhibits a target protein having an active site. In another aspect, the invention provides a method of selecting an agent that inhibits a target protein having an active site for further optimization. In some embodiments, the methods comprise measuring or predicting stability of an induced fit conformation of an agent contacted to an active site of the protein, wherein the agent is selected if the stability of the induced fit conformation of the agent contacted to the active site of the protein is increased relative to a reference stability.Type: GrantFiled: November 4, 2015Date of Patent: March 4, 2025Assignee: Brandeis UniversityInventor: Dorothee Kern
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Patent number: 12239982Abstract: Devices, methods, and kits are provided for allergy testing based on basophil activation in a blood sample. Susceptibility of an individual to an allergic reaction to an allergen is detected by collecting a blood sample from the individual and assaying for activation of basophils in response to stimulation with an allergen. In particular, a microfluidic device is provided for automating the assay for detecting basophil activation as an indication of the susceptibility of an individual to an allergic reaction as well as kits containing such a device and diagnostic methods for using such a device for allergy testing. Additionally, such a microfluidic device can be adapted for multiplexed detection of allergic responses to multiple allergens by performing assays in parallel to detect the basophil responses to each allergen.Type: GrantFiled: November 13, 2019Date of Patent: March 4, 2025Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Sindy K. Y. Tang, Kari C. Nadeau, Bryan J. Bunning, Nicolas Castano, Fengjiao Lyu, Seth Cordts
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Patent number: 12241857Abstract: Disclosed are systems and methods for delivering and/or linking molecules, such as DNA, between tunable metal nanogaps and measuring electrical and/or optical properties. In one example, disclosed are high density multiplexed chips with a plurality of groups, each group including a plurality of nanodevices, the chips capable of coupling to one or more multiwell structures for providing samples to each individual group. In this way, the chips can be used for high-throughput analysis of molecules such as DNA.Type: GrantFiled: March 15, 2022Date of Patent: March 4, 2025Assignee: Arizona Board of Regents on Behalf of Arizona State UniversityInventor: Quan Qing
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Patent number: 12244373Abstract: Described herein are systems, methods and devices for implementing a temperature-aware, multi-antenna scheduler that cools mmWave devices by preventing heat buildup via switching or distributing a data stream to other redundant antennas, allowing for dissipation of heat as well as providing reliable connectivity.Type: GrantFiled: February 9, 2023Date of Patent: March 4, 2025Assignee: University of South CarolinaInventors: Sanjib Sur, Moh. S. Saadat, Srihari Nelakuditi
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Patent number: 12239977Abstract: A method of manufacturing a microfluidic analytical device comprising providing a top lamination layer and a bottom lamination layer, wherein each of the top lamination layer and bottom lamination layer comprises an outer layer and an inner layer, cutting out one or more channel spaces from the at least one of the top lamination layer and the bottom lamination layer, wherein the one or more channel spaces form a microfluidic path, positioning at least one middle layer between the top lamination layer and the bottom lamination layer, such that each of the two inner layers face the at least one middle layer, and subjecting the top lamination layer and the bottom lamination layer to a process, wherein the process allows both the inner layers to permeate substantially through the at least one middle layer.Type: GrantFiled: November 2, 2022Date of Patent: March 4, 2025Assignee: New York University in Abu Dhabi CorporationInventors: Nityanand Kumawat, Soja Saghar Soman, Vijayavenkataraman Sanjairaj, Sunil Kumar
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Patent number: 12241305Abstract: Insulated assemblies, insulation units including an assembly, and methods of forming the assemblies and units are disclosed. Exemplary assemblies include a first pane of material, a second pane of material, and one or more monolithic insulating layers interposed between the first pane of material and the second pane of material. The insulating layer can exhibit a thermal conductivity less than 26 mW/(K.m).Type: GrantFiled: December 10, 2021Date of Patent: March 4, 2025Assignee: The Regents of the University of Colorado, a body corporateInventors: Blaise Fleury, Ivan I. Smalyukh, Jan Bart ten Hove, Vladyslav Cherpak, Eldho Abraham, Taewoo Lee, Bohdan Senyuk
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Patent number: 12239650Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of NETs in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating NET mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRI)). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of NET mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g., mCBS.Type: GrantFiled: February 25, 2019Date of Patent: March 4, 2025Assignees: The Australian National University, Griffith UniversityInventors: Christopher Parish, Connor O'Meara, Lucy Coupland, Benjamin Ju Chye Quah, Farzaneh Kordbacheh, Anna Orlov, Anna Browne, Ross Stephens, Gregory David Tredwell, Lee Andrew Philip, Karen Knox, Laurence Mark von Itzstein, Chih-Wei Chang, Anne Bruestle, David Anak Simon Davis
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Patent number: 12239696Abstract: Provided herein are chimeric recombinant polypeptides (chimeritopes) for use in vaccines against Anaplasmosis, in assays for diagnosing Anaplasmosis and in assays for measuring antibody titers induced by vaccination. The chimeritopes comprise, for example, antigenic segments of three Anaplasma proteins (OmpA, AipA and Asp14) and a non-antigenic segment of a Borrelia Osp protein (e.g. OspC) that is 10 amino acids in length, proline rich and random coil in conformation. Compositions comprising the chimeritopes, optionally in combination with additional Anaplasma proteins of interest, are also provided, as are methods of using the compositions as vaccines and diagnostic tools.Type: GrantFiled: February 1, 2022Date of Patent: March 4, 2025Assignee: Virginia Commonwealth UniversityInventors: Richard T. Marconi, Jason A. Carlyon
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Patent number: 12241901Abstract: Systems and methods for accurate optical pH sensing of biofilms are disclosed. In one embodiment, a method of measuring an extracellular pH level using multiple wavelengths emitted by a fluorescent substance includes: exciting the fluorescent substance at an excitation wavelength; measuring a first fluorescence intensity at a first wavelength of a fluorescence emission; and measuring a second fluorescence intensity at a second wavelength of the fluorescence emission. The second wavelength is different from the first wavelength. The method also includes determining the extracellular pH level based on the first fluorescence intensity at the first wavelength and the second fluorescence intensity at the second wavelength.Type: GrantFiled: July 19, 2019Date of Patent: March 4, 2025Assignee: The University of WashingtonInventors: Eric J. Seibel, Leonard Y. Nelson, Manuja Sharma, Jasmine Graham
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Patent number: 12240815Abstract: Disclosed are 2-aminopyridine derivative compounds for use as inhibitors of nitric oxide synthase (NOS). In particular, the field of the invention relates to 2-aminopyridine derivative compounds for use as inhibitors of neuronal nitric oxide synthase (nNOS), which are formulated as pharmaceutical compositions for treating diseases and disorders associated with nNOS such as Alzheimer's, Parkinson's, and Huntington's diseases, and amyotrophic lateral sclerosis, cerebral palsy, stroke/ischemic brain damage, and migraine headaches.Type: GrantFiled: February 24, 2021Date of Patent: March 4, 2025Assignee: Northwestern UniversityInventors: Richard B. Silverman, Ha T. Do