Patents Assigned to University
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Publication number: 20250065121Abstract: A system and method for the automatic stimulation of a vagus nerve for post-stroke rehabilitation is disclosed. The system includes an application subsystem having an electrode positioned to stimulate the vagus nerve and coupled to a user outside of a surgical setting. The system also includes a waveform generator communicatively coupled to the electrode, and a triggering subsystem including a receiver configured to detect the presence of a tag. The triggering subsystem is communicatively coupled to waveform generator and is configured to automatically trigger the stimulation of the vagus nerve upon detecting the presence of the tag. The tag is located proximate a rehabilitation context such that the tag is detected when the user is using the rehabilitation context, resulting in the vagus nerve of the user being automatically stimulated by the electrode in response to the user's post-stroke rehabilitation training.Type: ApplicationFiled: November 14, 2024Publication date: February 27, 2025Applicant: Arizona Board of Regents on Behalf of Arizona State UniversityInventors: Vishvak RANGARAJAN, Devin DHOOGE, Kiryl SHELEG, Nicholas HOLMES, Jeffrey KLEIM, Bradley GREGER, Shivanshi SHUKLA
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Publication number: 20250064056Abstract: Proposed are a contact pheromone-containing composition, a kit composition, and a method using the same for controlling thrips. A thrip control technology using a behavior-disrupting pheromone is provided to increase opportunities for the exposure of the thrips to pesticides. Contact pheromone (7MT) induced significant behavioral changes in adult thrips. Moreover, the addition of the contact pheromone increased an insecticidal effect. The composition contains the contact pheromone as an active ingredient, and the kit composition contains the contact pheromone of the thrips and pesticides against the thrips. The contact pheromone-containing composition shows a significant control effect on thrips. The kit composition and method, which use a contact pheromone and pesticide together, show a significantly increased control effect compared to the thrips control technologies that only apply existing pesticides.Type: ApplicationFiled: February 27, 2024Publication date: February 27, 2025Applicant: Andong National University Industry-Academic Cooperation FoundationInventor: Yong Gyun KIM
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Publication number: 20250066188Abstract: The present disclosure discloses a MEMS grating and a fabrication method. The MEMS grating includes a substrate layer, an insulation layer and a deformable layer. The deformable layer is made of a continuous conductive material, the insulation layer is distributed along transverse intervals on the substrate layer, and a cavity is formed between every two adjacent insulation layers. The deformable layer includes movable grating bars and fixed grating bars. The fixed grating bars are fixedly connected with the insulation layer, and the movable grating bars correspond to the cavities. A plurality of through holes are formed in the movable grating bars. During wet etching, the movable grating bars generate upwards buckling deformation, which increase an initial gap between the movable grating bars and a substrate. An adhesion effect caused by the wet etching is eliminated, which reduces permanent failures caused by the adhesion effect.Type: ApplicationFiled: November 8, 2023Publication date: February 27, 2025Applicant: Northwestern Polytechnical UniversityInventors: Yongqian Li, Datai Hui, Dayong Qiao
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Publication number: 20250066739Abstract: Media for making esophageal organoids, methods of making an esophageal organoid using that media, and esophageal organoids produced by those methodsType: ApplicationFiled: November 13, 2024Publication date: February 27, 2025Applicant: The Trustees of Columbia University in the City of New YorkInventors: Hiroshi NAKAGAWA, Anil K. RUSTGI
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Publication number: 20250066856Abstract: Provided are methods for identifying pancreatic cancer subtypes in a subject and treating the same. In some embodiments, the method comprise obtaining gene expression levels for each of the following genes in the biological sample: GPR87, KRT6A, BCAR3, PTGES, ITGA3, C16orf74, S100A2, KRTS, REG4, ANXA10, GATA6, CLDN18, LGALS4, DDC, SLC40A1, CLRN3; performing pair-wise comparisons of gene expression levels for combinations of these genes; and calculating a Raw Score for the biological sample, wherein the Raw Score is indicative of the pancreatic cancer subtype in the subject. Also provided are methods for identifying differential treatment strategies for subjects diagnosed with PDAC, methods for treating PDAC patients based on the subtype of PDAC the patients have; and methods for classifying subjects diagnosed with PDAC as having a basal-like subtype or a classical subtype of PDAC.Type: ApplicationFiled: April 29, 2024Publication date: February 27, 2025Applicant: The University of North Carolina at Chapel HillInventors: Jen Jen Yeh, Richard Moffitt, Naim Ur Rashid
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Publication number: 20250066315Abstract: The invention provides neo acids (NAs) and derivatives thereof. Also provided is a method for producing a NA, comprising hydrodeoxygenation (HDO) of a furan-containing neo acid (FNA) in the presence a metal triflate and a hydrogenation catalyst. The NA production method may further comprise hydroxyalkylation/alkylation (HAA) of 2-alkylfuran with levulinic acid or pyruvic acid in the presence of an acid catalyst, and at least one of 2-alkylfuran, levulinic acid and pyruvic acid may be from a renewable carbon source. The NA may have a bio-based content in the range of 20-100% according to, for example, ASTM-D6866. Further provided are methods for producing branched alkanes (BAs), tertrahydrofuran-containing neo acid (THFNA) and furan-containing neo ester (FNE) and side products such as iso acids (IAs).Type: ApplicationFiled: December 16, 2022Publication date: February 27, 2025Applicant: University of DelawareInventors: Sunitha Sadula, Erha Andini, Dionisios G. Vlachos
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Publication number: 20250069788Abstract: A magnetoelectric multiferroic nanocomposite. The nanocomposite comprises a ferroelectric perovskite oxide and a rare-earth substituted mixed ternary transition metal ferrite of the formula A1-xBxRyFe2-yO4. The nanocomposite has a high dielectric constant, low dielectric loss, both stable over a wide frequency range. These properties may make the nanocomposite desirable for applications in microelectronic devices, sensors and antennas.Type: ApplicationFiled: November 8, 2024Publication date: February 27, 2025Applicant: Imam Abdulrahman Bin Faisal UniversityInventors: Yassine SLIMANI, Munirah Abdullah ALMESSIERE, Abdulhadi BAYKAL
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Publication number: 20250065750Abstract: A power supply apparatus includes a power reception coil mounted to a moving object, a plurality of relay coils, and a power reception circuit connected with the power reception coil. The relay coils are configured to successively relay supply of electric power from a power transmission coil, which is arranged along a surface on which the moving object moves, to the power reception coil during movement of the moving object. Each of the relay coils includes a first coil and a second coil, which are configured to be magnetic-field-coupled respectively to the power transmission coil and the power reception coil, and a connection circuit that connects the first and second coils. The connection circuit includes at least one resonance capacitor involved in setting of a resonance frequency of at least one of the first and second coils. The at least one resonance capacitor has a parallel characteristic.Type: ApplicationFiled: November 14, 2024Publication date: February 27, 2025Applicants: DENSO CORPORATION, The University of TokyoInventors: Hayato SUMIYA, Eisuke TAKAHASHI, Nobuhisa YAMAGUCHI, Hiroshi FUJIMOTO, Osamu SHIMIZU
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Publication number: 20250066662Abstract: A luminescent probe and its preparation method and application are provided. The luminescent probe has a steric hindrance group R1 of aliphatic hydrocarbon structure such as adamantane or norborneol, a detection group R2 of nitrobenzyl and its derivative structure, an electron-withdrawing group R3 containing cyano group and an electron-donating group methoxy group. In the presence of HSA or BSA, the detection group is cut off to form a parent structure that exposes atomic oxygen anions and is activated under external light irradiation, the luminescent probe can be used in solution or cells, when detecting HSA or BSA, the luminescent probe has obvious chemiluminescence characteristics, which can sensitively distinguish HSA and BSA, quantitatively analyze HSA and BSA, and determine the mixing ratio of HSA and BSA at the same time, and the luminescent probe has been successfully used for cell fluorescence imaging.Type: ApplicationFiled: July 10, 2024Publication date: February 27, 2025Applicant: East China University of Science and TechnologyInventors: Zhiqian GUO, Juan LI, Yutao ZHANG, Yao LU, Chenxu YAN, Meiling ZHAO, Xiuyan ZHAO, Weihong ZHU
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Publication number: 20250066848Abstract: This disclosure is related to a method of sequencing a single-stranded DNA using deoxynucleotide polyphosphate analogues and translocation of tags from incorporated deoxynucleotide polyphosphate analogues through a nanopore.Type: ApplicationFiled: November 12, 2024Publication date: February 27, 2025Applicant: The Trustees of Columbia University in the City of New YorkInventors: Jingyue Ju, Shiv Kumar, Zengmin Li, Chuanjuan Tao, Minchen Chien, James J. Russo, Sergey Kalachikov, Ken Shepard, Jacob Karl Rosenstein
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Publication number: 20250072030Abstract: A device includes a substrate, a semiconductor layer and a ferroelectric layer. The semiconductor layer is over the substrate. The semiconductor layer is a single crystal silicon layer or a single crystal germanium layer. The ferroelectric layer is over the semiconductor layer. The ferroelectric layer is in physical contact with the semiconductor layer and has an orthorhombic phase.Type: ApplicationFiled: August 23, 2023Publication date: February 27, 2025Applicants: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD., National Yang Ming Chiao Tung UniversityInventors: Yu-Rui CHEN, Zefu ZHAO, Yun-Wen CHEN, Chee-Wee LIU
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Publication number: 20250068841Abstract: Embodiments can take brain activity measurement and decode into continuous language. Embodiment can use non-invasive brain recordings, such as functional magnetic resonance imaging (fMRI) and functional near-infrared spectroscopy (fNIRS) to detect changes in blood oxygen level that are coupled to neural activity. These brain recordings can be used by a language reconstruction model that involves a neural language model to predict a next word in a sequence and an encoding model to decode the recordings into continuous language, or sequences of words.Type: ApplicationFiled: February 22, 2023Publication date: February 27, 2025Applicant: Board of Regents, The University of Texas SystemInventors: Alexander Huth, Jerry Tang
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Publication number: 20250067722Abstract: Processes for conductive material nanogap formation have been developed that include: providing a base material, wherein the base material is either solid or comprises a micropore that extends through the first layered material, and wherein the micropore comprises a top opening, a bottom opening, and a volume boundary, applying a conductive material sheet to the first layered material, wherein the conductive material sheet covers the top opening of the micropore, applying two conducting electrodes to the conductive material sheet, so that each one of the conducting electrodes is positioned on either side of the micropore, applying an etch mask that covers at least a part of the conductive material sheet, the top opening of the micropore (if present), or a combination thereof, applying a passivation layer over at least the etch mask, fabricating a hole in the passivation layer directly above the top opening of the micropore, and applying at least one voltage pulse through the at least one conducting electrodeType: ApplicationFiled: September 9, 2024Publication date: February 27, 2025Applicant: The Trustees of the California State UniversityInventor: Hendrik Postma
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Publication number: 20250066444Abstract: Glucagon promoters are disclosed herein. In addition, disclosed are recombinant nucleic acid molecules that include a glucagon promoter operably linked to a nucleic acid molecule encoding at least one heterologous protein. Vectors including these recombinant nucleic acid molecules, and host cells transformed with these vectors, are also disclosed. Methods of use for these promoters, recombinant nucleic acid molecules, vectors and host cells are disclosed.Type: ApplicationFiled: January 3, 2023Publication date: February 27, 2025Applicant: University of Pittsburgh - Of the Commonwealth System of Higher EducationInventors: George Gittes, Ting Zhang
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Publication number: 20250066741Abstract: Compositions of matter and methods for using the composition of matter may be provided. The method may include providing a virus-like particle (VLP) comprising C. elegans retrotransposon 1 (Cer1) and a heterologous RNA-based agent to an organism and allowing the organism to transfer the heterologous RNA-based agent to a tissue within the organism.Type: ApplicationFiled: July 26, 2022Publication date: February 27, 2025Applicant: The Trustees of Princeton UniversityInventors: Coleen T. MURPHY, Rachel KALETSKY, Rebecca S. MOORE
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Publication number: 20250066831Abstract: A prokaryote was genetically engineered to develop operationally simple, high-yield biosynthetic route for the production of farnesylated proteins. The recombinant organism was modified to express a target protein, a peptide sequence fused to the target protein at a C-terminus, and an alpha and a beta subunit of a prenyltrasferase. The prenyltrasferase may be farnesyltransferase or geranylgeranyl transferase, and the peptide sequence may comprise cysteine, two hydrophobic amino acids, and an amino acid having selectivity to farnesyltransferase or geranylgeranyl transferase.Type: ApplicationFiled: December 21, 2022Publication date: February 27, 2025Applicant: Syracuse UniversityInventors: Shahadat Hossain, James Hougland, Davoud Mozhdehi
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Publication number: 20250065290Abstract: A method for generation of material in a liquid phase comprising a step of subjecting the liquid phase to a nanosecond-pulsed discharge plasma.Type: ApplicationFiled: September 5, 2024Publication date: February 27, 2025Applicant: Drexel UniversityInventors: Danil V. Dobrynin, Alexander Fridman
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Publication number: 20250072275Abstract: A compound comprising a first ligand LA comprising a structure of Formula I, is provided. In Formula I, each of moiety A and moiety B is a monocyclic ring or a polycyclic fused ring system; each of X1 to X4 and Z1 to Z4 is C or N; at least one of X1 to X4 is N; each of K1 and K2 is a direct bond or a linker; Y is a linker; each R, R?, R?, R?, RA, RB, and RC is hydrogen or a substituent; LA is coordinated to a metal M; and at least one of five conditions related to X1 to X4 and/or RC is met. Formulations, OLEDs, and consumer products containing the compound are also provided.Type: ApplicationFiled: May 21, 2024Publication date: February 27, 2025Applicant: Universal Display CorporationInventors: Alexey Borisovich DYATKIN, Wei-Chun SHIH, Tyler FLEETHAM, Pierre-Luc T. BOUDREAULT, Jui-Yi TSAI, Jerald FELDMAN
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Publication number: 20250072276Abstract: An organic light emitting device (OLED) comprising, sequentially an anode; a hole transporting layer; an emissive region; an electron transporting layer; and a cathode is provided. In the OLED, the emissive region comprises a compound S1 and a compound A1, where the compound S1 is an organometallic sensitizer that transfers energy to the compound A1, and the compound A1 is an acceptor that is an emitter; the compound A1 has an emission onset greater than 750 nm; and the PLQY of the emissive region comprising both compound S1 and compound A1 is greater than the PLQY of an equivalent emissive region without compound A1. Consumer products containing the OLED are also provided.Type: ApplicationFiled: July 26, 2024Publication date: February 27, 2025Applicant: Universal Display CorporationInventors: Eric A. MARGULIES, Tyler FLEETHAM, Rasha HAMZE, Sean Michael RYNO
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Publication number: 20250072155Abstract: Disclosed are embodiments of a thin-film photovoltaic technology including a single-junction crystalline silicon solar cell with a photonic-plasmonic back-reflector structure for lightweight, flexible energy conversion applications. The back-reflector enables high absorption for long-wavelength and near-infrared photons via diffraction and light-concentration, implemented by periodic texturing of the bottom-contact layer by nanoimprint lithography. The thin-film crystalline silicon solar cell is implemented in a heterojunction design with amorphous silicon, where plasma enhanced chemical vapor deposition (PECVD) is used for all device layers, including a low-temperature crystalline silicon deposition step. Excimer laser crystallization is used to integrate crystalline and amorphous silicon within a monolithic process, where a thin layer of amorphous silicon is converted to a crystalline silicon seed layer prior to deposition of a crystalline silicon absorber layer via PECVD.Type: ApplicationFiled: November 7, 2024Publication date: February 27, 2025Applicants: Pacific Integrated Energy, Inc., Iowa State University Research Foundation, Inc.Inventors: Vikram Dalal, David Keogh