Abstract: A system for precision liquid delivery includes a gas reservoir having a known volume. The system has a tightly load-coupled pneumatic driver (a “TLCP driver”) that is configured to receive input power to cause the TLCP driver to move gas into the gas reservoir to produce a gas drive pressure. A valve is configured to couple the gas reservoir with a fluid reservoir having an unknown volume. The valve is further configured to selectively isolate or pneumatically couple pressures in the gas reservoir and the fluid reservoir. A gas-fluid interface couples pressure in the fluid reservoir to pressure in a fluid path. The fluid path is configured so that the fluid drive pressure driving the liquid in the fluid path is substantially the same as the fluid reservoir pressure. The system also has a pressure sensor configured to detect pressure in the gas reservoir and/or the fluid reservoir.
Type:
Grant
Filed:
December 13, 2022
Date of Patent:
February 27, 2024
Assignee:
Pneuma Systems Corporation
Inventors:
Jeffrey A. Carlisle, Timothy S. Schroeder, Thomas C. Plummer
Abstract: A method of producing trifluoroiodomethane (CF3I) includes providing a feedstock comprising trifluoroacetyl iodide (TFAI), passing the feedstock through at least one column charged with carbonaceous materials to remove hydrogen iodide (HI), hydrogen triiodide (HI3) and iodine (I2) from the feedstock, and providing the feedstock to a reactor to produce a trifluoroiodomethane product stream. Another method of producing trifluoroiodomethane (CF3I) includes providing a feedstock comprising trifluoroacetyl iodide (TFAI) to a reactor to produce a trifluoroiodomethane product stream, and passing the trifluoroiodomethane product stream from the reactor through at least one column charged with carbonaceous materials to remove hydrogen iodide (HI), hydrogen triiodide (HI3) and iodine (I2) from the trifluoroiodomethane product stream.
Abstract: Disclosed are inhibitors for the ?-catenin/BCL9 interaction. The inhibitors are selective for ?-catenin/BCL9 over ?-catenin/cadhenin interactions. Methods of using the disclosed compounds to treat cancer are also disclosed.
Type:
Grant
Filed:
December 30, 2022
Date of Patent:
February 20, 2024
Assignee:
H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC.
Abstract: A method for controlling the temperature of a compressor having a motor including a rotor and a stator, and a control assembly operably coupled to the compressor, the method comprising the steps of: applying an initial current to the compressor motor; measuring a voltage across the compressor motor and determining a resistance of the compressor motor based on the initial current and a measured voltage; determining whether the determined resistance is less than or equal to a desired resistance; applying a secondary current to the compressor motor if the determined resistance is less than or equal to the desired resistance.
Abstract: The subject invention pertains to a method of halogenating phenols, yielding a range of halogenated phenols with enantiomeric ratio of up to 99.5:0.5. In certain embodiments, the subject invention pertains to a method of asymmetric halogenation of bisphenol, yielding a range of chiral bisphenol ligands. The novel chiral bisphenols are potent privileged catalyst cores that can be applied to the preparation of ligands for various catalytic asymmetric reactions. The catalyst library can easily be accessed because late-stage modification of the scaffold can readily be executed through cross-coupling of the halogen handles on the bisphenols.
Abstract: The present invention provides a method for preparing 2,2-bis(4-hydroxycyclohexyl)propane, comprising: hydrogenating a reactive solution containing 2,2-bis(4-hydroxyphenyl)propane under a hydrogen atmosphere in a reactor with catalyst within a temperature range of 80-165° C. and a pressure range of 85-110 kg/cm2 to prepare the 2,2-bis(4-hydroxycyclohexyl)propane. The method of present invention has an advantage of high yield properties and achieves mass production easily, thereby enhancing the value of the industrial application.
Type:
Grant
Filed:
June 14, 2022
Date of Patent:
February 20, 2024
Assignee:
CHINA PETROCHEMICAL DEVELOPMENT CORPORATION, TAIPEI (TAIWAN)
Abstract: A semiconductor manufacturing apparatus including a plurality of process modules for performing desired processes on a plurality of substrates and a plurality of transfer modules for serially transferring the plurality of substrates to the plurality of process modules is provided. The semiconductor manufacturing apparatus comprises a scheduler for calculating a cycle time so that a difference in time required for each of the desired processes is within an allowable time range and generating a transfer plan for the plurality of substrates based on the cycle time, and a transfer controller for controlling the plurality of transfer modules so that the plurality of substrates are serially transferred to the process modules according to the generated transfer plan.
Abstract: Embodiments described herein provide a method, comprising reducing pH of a glycol vaporization separator purge stream to form an acid stream; distilling the acid stream to form an overhead stream and a bottoms stream; and recycling the bottoms stream to the vaporization separator.