Patents Examined by Alton D. Rollins
  • Patent number: 4414210
    Abstract: This invention relates to 2-hydroxyarylethyl-1,2,4-triazoles, their acid addition salts and metal salt complexes. This invention also relates to the method of preparation and use of these compounds. These compounds and salts thereof are highly active broad-spectrum systemic fungicides effective in controlling phytopathogenic fungi such as barley net blotch (Helminthosporium teres), grey mold (Botrytis fabae), bean powdery mildew (Erysiphe polygoni), grape downy mildew (Plasmopora viticola), rice blast (Piricularia oryzae), tomato late blight (Phytophthora infestans) and wheat stem rust (Puccinia graminis f. sp. tritici race 158-2).
    Type: Grant
    Filed: May 19, 1981
    Date of Patent: November 8, 1983
    Assignee: Rohm and Haas Company
    Inventors: George A. Miller, Hak-Foon Chan
  • Patent number: 4413131
    Abstract: Disclosed are compounds of formula I, ##STR1## in which the R.sub.1 's, independently, are chlorine or bromine, andR.sub.2 is fluorine, chlorine, bromine, methyl, ethyl, ethoxy or tri-fluoromethyl,their production and use as pigments.
    Type: Grant
    Filed: July 11, 1977
    Date of Patent: November 1, 1983
    Assignee: Sandoz Ltd.
    Inventor: Dimitrios Karanatsios
  • Patent number: 4412079
    Abstract: Novel thiadiazole compounds are disclosed which contain in the 5 position, C-linked moieties which are either acyclic hydrocarbon radicals or halogenated acyclic hydrocarbon radicals (in which case each halogen is independently selected from F, Cl and Br). These novel compounds also contain an exocyclic nitrogen in the 2 position, and some of them contain the exocyclic substituent: ##STR1## wherein R.sub.3 is a lower acyclic hydrocarbon radical and R.sub.4 is either H or a lower acyclic hydrocarbon radical. Synthesis of these compounds is disclosed, including synthesis of those which exhibit isomerism and/or tautomerism.Various of these compounds have various agricultural utilities (e.g. as herbicides, insecticides, acaricides and fungicides), each of them having at least one such biological utility. Methods of using these compounds in phytotoxic fungicidal, acaricidal and insecticidal applications are disclosed.
    Type: Grant
    Filed: September 20, 1982
    Date of Patent: October 25, 1983
    Assignee: Air Products and Chemicals, Inc.
    Inventors: Tony Cebalo, Robert A. Walde
  • Patent number: 4411905
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is H or NH.sub.2 ; R.sub.2 is C.sub.1-6 straight or branched chain alkyl; --CH.sub.2 OH; --(CH.sub.2).sub.n --O--(CH.sub.2).sub.m --CH.sub.3 ; phenyl; or --(CH.sub.2).sub.p NH.sub.2 ;n is 1-3;m is 0-3; andp is 1-5;and the pharmaceutically acceptable acid addition salts of those compounds of basic character,have antisecretory activity.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: October 25, 1983
    Assignee: Richardson-Merrell Inc.
    Inventors: William L. Albrecht, Winton D. Jones
  • Patent number: 4411687
    Abstract: .alpha.-Azolyl-glycol derivatives of the formula ##STR1## where R.sup.1 is alkyl,R.sup.2 is alkyl or unsubstituted or substituted phenyl,R.sup.3 is hydrogen, alkyl, alkenyl, alkynyl or unsubstituted or substituted benzyl,R.sup.4 is unsubstituted or substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, arylalkyl or heteroarylalkyl or, where n=1, may also be unsubstituted or substituted aryl or heteroaryl,X is CH or N andn is O or 1,their salts and metal complexes tolerated by crop plants, their preparation, and agents containing these derivatives for controlling fungi and regulating plant growth.
    Type: Grant
    Filed: September 18, 1981
    Date of Patent: October 25, 1983
    Assignee: BASF Aktiengesellschaft
    Inventors: Bernd Zeeh, Norbert Goetz, Eberhard Ammermann, Ernst-Heinrich Pommer
  • Patent number: 4410708
    Abstract: Certain 3-substituted amino-7-substituted fluoran derivatives useful as color recording materials.
    Type: Grant
    Filed: February 3, 1976
    Date of Patent: October 18, 1983
    Assignee: Shin Nisso Kako Co., Ltd.
    Inventors: Masakichi Yahagi, Shoichi Horiuchi, Takahumi Toyama, Akio Kashiwagi, Teruo Suzuki, Tetsuo Igaki, Kazuyuki Horisawa, Mituhiro Shoji
  • Patent number: 4410703
    Abstract: Lubricants are stabilized against wear and corrosion by adding an additive amount of a novel substituted thiadiazole. These are derived from 2,5-dimercapto-1,3,4-thiadiazole and other moieties, as for example, an isocyanate moiety.
    Type: Grant
    Filed: August 10, 1981
    Date of Patent: October 18, 1983
    Assignee: Mobil Oil Corporation
    Inventor: Abraham O. M. Okorodudu
  • Patent number: 4409145
    Abstract: Novel 4-phenyl-1,3-benzodiazepines, novel intermediates thereof, and methods of preparing same are described. These benzodiazepines are useful as antidepressants, analgetics and anticonvulsants.
    Type: Grant
    Filed: September 8, 1981
    Date of Patent: October 11, 1983
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Lawrence L. Martin, Manfred Worm, Charles A. Crichlow
  • Patent number: 4409388
    Abstract: Novel 1,2,4-triazole derivatives are described having the following formula ##STR1## wherein R represents hydrogen or methyl, R.sub.1 stands for hydrogen or (C.sub.1 -C.sub.4)alkyl, or R and R.sub.1 taken together may represent a further bond between the carbon atom and the oxygen atom, R.sub.2 and R.sub.4, each independently, represent hydrogen, chloro, fluoro, bromo, (C.sub.1 -C.sub.4)alkyl or (C.sub.1 -C.sub.4)alkoxy, R.sub.3 stands for (C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, allyloxy, propargyloxy, trifluoromethyl, phenyl, chloro, fluoro, bromo or dimethylamino or R.sub.3 and R.sub.4 taken together may represent a methylenedioxy group.Also described is a process for their manufacture.Use of the novel compounds as antireproductive agents and pharmaceutical compositions containing them as active ingredients are also claimed.
    Type: Grant
    Filed: October 23, 1979
    Date of Patent: October 11, 1983
    Assignee: Gruppo Lepetit S.p.A.
    Inventors: Amedeo Omodei-Sale', Pietro Consonni, Giulio Galliani
  • Patent number: 4406909
    Abstract: A fungicidally active 4-substituted-1-azolyl-1-phenoxy-3,3-dimethyl-butan-2-one or -ol of the formula ##STR1## in which A is a nitrogen atom or CH,B is --CO-- or CH(OH),R is cyano or X--R.sup.1,R.sup.1 is alkyl, optionally substituted aryl or optionally substituted aralkyl,X is oxygen, sulphur, SO or SO.sub.2,Z each independently is halogen, alkyl, halogenoalkyl, alkoxy, alkylthio, alkylsulphonyl, nitro, cyano, alkoxycarbonyl or optionally substituted phenyl, andn is 0, 1, 2 or 3,or an addition product thereof with a physiologically acceptable acid or with a metal salt. Intermediates therefor of the formula ##STR2## are also new.
    Type: Grant
    Filed: May 19, 1981
    Date of Patent: September 27, 1983
    Assignee: Bayer Aktiengesellschaft
    Inventors: Wolfgang Kramer, Hans-Ludwig Elbe, Karl H. Buchel, Wilhelm Brandes, Paul-Ernst Frohberger
  • Patent number: 4406910
    Abstract: Pesticidal 3-(2,3-dihydro-2-alkylbenzofuran-7-yl)-5-(R-oxy)-1,3,4-oxadiazol-2(3H)-one s.
    Type: Grant
    Filed: May 6, 1982
    Date of Patent: September 27, 1983
    Assignee: Shell Oil Company
    Inventors: Kurt H. Pilgram, Richard D. Skiles
  • Patent number: 4404137
    Abstract: Compounds are described of the formula ##STR1## or an acid addition salt thereof; in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently represent hydrogen, C.sub.1-4 alkyl, C.sub.2-4 alkenyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycloalkyl C.sub.1-4 alkyl, halogen, C.sub.1-4 haloalkyl, C.sub.1-4 alkanoyl, nitro, amino, C.sub.2-4 acylamino, cyano, hydroxyl, C.sub.1-4 alkoxy, C.sub.1-4 alkylthio, C.sub.1-4 haloalkoxy or a group of the formula --SO.sub.2 N(R.sup.8).sub.2, --SO.sub.2 R.sup.8 or --SO.sub.3 R.sup.8 where R.sup.8 is C.sub.1-4 alkyl, C.sub.1-4 haloalkyl or optionally substituted phenyl; in which R.sup.5 is a group of the formula ##STR2## where R.sup.9 is hydrogen, C.sub.1-4 alkyl, C.sub.3-7 cycloalkyl, C.sub.3-7 cycloalkyl C.sub.1-4 alkyl, C.sub.1-4 haloalkyl, C.sub.2-4 alkenyl, C.sub.1-4 alkanoyl, benzyl, cyano or optionally substituted phenyl, where R.sup.10 is hydrogen, C.sub.1-4 alkyl or optionally substituted phenyl and where n is 0 or 1; in which R.sup.6 is hydrogen, C.sub.1-10 alkyl, C.sub.
    Type: Grant
    Filed: October 2, 1980
    Date of Patent: September 13, 1983
    Assignee: Lilly Industries Limited
    Inventors: Jiban K. Chakrabarti, Terrence M. Hotten
  • Patent number: 4404019
    Abstract: A compound of the formula: ##STR1## wherein R is a C.sub.1 -C.sub.4 alkyl group, a C.sub.3 -C.sub.4 alkenyl group or a C.sub.3 -C.sub.4 cycloalkyl group, X is a chlorine atom or a bromine atom and Y is a hydrogen atom or a C.sub.1 -C.sub.4 alkoxy group, which is useful as a herbicide.
    Type: Grant
    Filed: December 8, 1981
    Date of Patent: September 13, 1983
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Tamon Uematsu, Shunichi Hashimoto, Hiroshi Matsumoto
  • Patent number: 4404390
    Abstract: Mesoionic 1,2,4-triazolium-3-thiolate silver halide stabilizer precursors are novel compounds useful in a heat developable and heat stabilizable photographic silver halide materials and processes. After imagewise exposure of the photographic material, a developed and stabilized silver image is produced by heating the element. Mesoionic stabilizer precursors are also useful in photographic silver halide processing compositions.
    Type: Grant
    Filed: November 9, 1981
    Date of Patent: September 13, 1983
    Assignee: Eastman Kodak Company
    Inventors: Henry W. Altland, Daniel D. Shiao
  • Patent number: 4404216
    Abstract: 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol and its pharmaceutically acceptable acid addition salts are disclosed. This particular bis-triazole derivative and its aforesaid salts are useful for treating fungal infections in animals, including humans. Methods for preparing these compounds from known starting materials are provided.
    Type: Grant
    Filed: June 1, 1982
    Date of Patent: September 13, 1983
    Assignee: Pfizer Inc.
    Inventor: Kenneth Richardson
  • Patent number: 4402963
    Abstract: There are described novel compounds of the formula I defined herein ##STR1## wherein R is a phenyl group which is unsubstituted or mono- to tetra-substituted by C.sub.1 -C.sub.4 -alkyl, halogen, nitro, cyano, trifluoromethyl, phenyl or C.sub.1 -C.sub.3 -alkoxy, or it is 3,4-methylenedioxy-phenyl, including the acid addition salts thereof with organic and inorganic acids as well as metal complexes thereof, all having tolerance to cultivated plants and possessing valuable microbicidal properties. They can be used for combating phytopathogenic microorganisms, particularly phytopathogenic fungi. The compounds of the formula I have for practical purposes a very favorable curative, systemic and preventive action for the protection of cultivated plants, without these being impaired as a result of undesirable side-effects. They can be used in practice on their own or in the form of microbicidal compositions.
    Type: Grant
    Filed: December 7, 1981
    Date of Patent: September 6, 1983
    Assignee: Ciba-Geigy Corporation
    Inventor: Elmar Sturm
  • Patent number: 4401822
    Abstract: N-(1-lower alkyl or alkenyl-2-pyrrolidinylmethyl)-2-lower alkoxy-4-amino-ower alkylsulphonylbenzamides and derivatives thereof which have antiapomorphine and antiserotonin activity.
    Type: Grant
    Filed: October 9, 1981
    Date of Patent: August 30, 1983
    Assignee: Societe de'Etudes Scientifiques et Industrielles de l'Ile-de France
    Inventors: Michel Thominet, Jacques Acher, Jean-Claude Monier
  • Patent number: 4400388
    Abstract: 1-Phenyl-2-(1,2,4-triazol-1-yl)-ethyl ethers of the formula ##STR1## in which R is halogen, alkyl, alkoxy, alkylthio, alkylsulfonyl, halogenoalkyl, nitro, cyano, optionally substituted phenyl or optionally substituted phenoxy,R' is alkyl, alkenyl, alkynyl, optionally substituted phenyl, optionally substituted benzyl or optionally substituted styryl, and n is 0, 1, 2 or 3,and their salts, which possess fungicidal and bactericidal properties.
    Type: Grant
    Filed: May 29, 1979
    Date of Patent: August 23, 1983
    Assignee: Bayer Aktiengesellschaft
    Inventors: Helmut Timmler, Karl H. Buchel, Wilhelm Brandes, Paul-Ernst Frohberger, Hans Scheinpflug
  • Patent number: 4400199
    Abstract: Chloroalkylthiolcarbamate compounds of the formula: ##STR1## wherein Z represents ##STR2## and when Z is ##STR3## n is an integer of 4 to 10, whereas when Z is ##STR4## n is an integer of 3 to 10. These compounds are useful as effective herbicides having no harmful effect on the ecosystem, particularly extremely low toxicity to fish, and can be obtained, for example, by reacting the corresponding thiolcarbamate derivatives with a chloroalkyl halide.
    Type: Grant
    Filed: October 29, 1981
    Date of Patent: August 23, 1983
    Assignee: Asahi Kasei Kabashiki Kaisha
    Inventors: Shigeo Yokoyama, Teruyuki Misumi, Einosuke Fujimoto, Yutaka Kobayashi
  • Patent number: 4400517
    Abstract: 1,2,4-triazol-(5)-yl-[thio] phosphates are disclosed having the formula ##STR1## wherein R.sup.1 =alkyl with from 1 to 5 carbon atoms;R.sup.2 =OR.sup.1, R.sup.1, C.sub.6 H.sub.5, NHR.sup.1, N(R.sup.1).sub.2 ;X=O, SR.sup.3 =H, alkyl with from 1 to 5 carbon atoms, C.sub.6 H.sub.5, benzyl, alkenyl with from 2 to 6 carbon atoms, alkynyl with from 2 to 6 carbon atoms; andR.sup.4 =vinyl, halovinyl, polyhalovinyl, vinyl substituted with aryl groups, alkyl groups with from 1 to 4 carbon atoms, O-alkyl groups with from 1 to 4 carbon atoms, S-alkyl groups with from 1 to 4 carbon atoms; haloalkyl, acetyl, cyclohexenyl, benzoyl ##STR2## Also disclosed are 1,2,4-triazole intermediates having the formula ##STR3## wherein: X, R.sup.3 and R.sup.4 have the same meanings as indicated above. The phosphate esters are useful in combatting infestations of pests such as orthoptera, aphides, diptera, lepidoptera, coleoptera, acari, nematodes.
    Type: Grant
    Filed: January 29, 1980
    Date of Patent: August 23, 1983
    Assignee: Montedison S.p.A.
    Inventors: Franco Gozzo, Pier M. Boschi, Angelo Longoni