Abstract: A compound of the formula: ##STR1## wherein R.sup.1 is hydrogen, C.sub.1 -C.sub.8 alkyl, unsubstituted benzyl or benzyl substituted with halogen methyl, ethyl, propyl, butyl, nitro, trifluoromethyl, cyano, methoxy, ethoxy, phenyl or methylenedioxy; R.sup.2 is hydrogen or C.sub.1 -C.sub.8 alkyl; Y is hydrogen, halogen, nitro, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, unsubstituted amino or methyl- or ethyl-substituted amino, and n is 1 or 2; each of the groups Y being the same or different when n is 2 and Y being other than hydrogen or halogen when R.sup.1 and R.sup.2 are both hydrogen; or a fungicidal acid salt or metal complex of said compound. Fungicidal compositions containing these compounds and methods of using the same to combat plant fungal diseases are also disclosed.

Abstract: A substituted azolyl-phenoxy derivative of the formula ##STR1## in which A is a nitrogen atom or a CH group,B is a keto group or a CH(OH) grouping,R.sup.1 is an alkyl or halogenoalkyl group of an optionally substituted aryl group,R.sup.2 is a hydrogen atom, an alkyl group or an optionally substituted phenyl group,R.sup.3 is a hydrogen atom, an alkyl, alkenyl or alkinyl group,m is 1 or 2,X is a halogen atom, or an alkyl, alkoxy, alkylthio, halogenoalkyl, halogenoalkoxy or halogenoalkylthio group, andn is 0, 1 or 2,or an addition product thereof with an acid or metal salt, which possesses fungicidal activity particularly for combating cereal diseases as well as rust and scab diseases.

Abstract: A 2-azolylmethyl-1,3-dioxolane or -dioxane derivative of the formula ##STR1## in which Az is imidazol-1-yl or 1,2,4-triazol-1-yl,R.sup.1, R.sup.2, R.sup.3 and R.sup.5 each independently is hydrogen or alkyl, orR.sup.1 and R.sup.3 together are an optionally substituted multi-membered methylene bridge,R.sup.4 is hydrogen, optionally substituted alkyl, optionally substituted aryl or optionally substituted aralykyl,m is 0 or 1,R.sup.6 is hydrogen, halogen, cyano, alkyl, optionally substituted aryl, --X--R.sup.7, --COOR.sup.8 or --CONHR.sup.9,X is oxygen, sulphur, SO, or SO.sub.2,R.sup.7 is alkyl, halogenoalkyl, cyano, optionally substituted aralkyl or optionally substituted aryl,R.sup.8 is alkyl,R.sup.9 is alkyl or optionally substituted aryl, andn is 0 or 1, or a plant-tolerated acid addition salt or metal salt complex thereof which possesses fungicidal activity.

Abstract: 3-Aralkyloxy-2,3-dihydro-2-(triazolylmethyl)benzo(b)thiophenes and related derivatives having antifungal, antibacterial, and antiprotozoal activity are prepared by the reaction of the corresponding 2,3-dihydro-3-hydroxy-2-(triazolylmethyl)benzo(b)thiophene or related derivative and an aralkyl halide.Preferred compounds are those where the aralkyl function is a hetercyclic aromatic, particularly 2-chloro-3-thenyl, and where the benzene nucleus is substituted by chlorine or fluorine.Pharmaceutical formulations comprising compounds of this invention are described, as well as the method for their use in treating microbial infections.

Abstract: Glycidyl-1,2,4-triazolidine-3,5-diones corresponding to the general formula I ##STR1## wherein R.sup.1 represents a mono- to pentavalent substituted or unsubstituted straight-chain or branched-chain C.sub.1 -C.sub.3 O aliphatic group, a mono- to pentavalent substituted or unsubstituted C.sub.5 -C.sub.21 cycloaliphatic group, a mono- to pentavalent substituted C.sub.7 -C.sub.17 aliphatic-aromatic group or a mono- to pentavalent substituted or unsubstituted C.sub.6 -C.sub.21 aromatic group, the above mentioned aliphatic group being optionally interrupted by one or more oxygen atoms or tertiary nitrogen atoms, and the above mentioned aliphatic-aromatic, polynuclear and cycloaliphatic polynuclear aromatic groups being optionally interrupted by at least one oxygen or tertiary nitrogen atom or by at least one C.sub.1 -C.sub.4 alkylene group or by at least one sulphonyl group ##STR2## R.sup.2 and R.sup.

Abstract: Compounds of the formula ##STR1## wherein X is an amine function and R is substituted phenyl and their pharmaceutically acceptable salts are useful antifungal agents in animals, including man.

Abstract: Manufacture of 3-hydroxy-1,2,4-triazoles by cyclization of corresponding semicarbazides by formic acid in the presence of an inorganic acid or halide thereof.

Abstract: New azolylvinyldithioacetals of the formula ##STR1## in which R.sup.1 is an alkyl, optionally substituted cycloalky, optionally substituted phenyl or alkoxy group,R.sup.2 and R.sup.3 are identical and each is an alkyl, alkenyl, alkinyl, optionally substituted benzyl or trialkylsilyl group,R.sup.2 and R.sup.3 together form an alkylene chain, a dialkylsilyl bridge or a --CH.dbd.CH-- group,X is a keto group or a CH--(OH) group, andY is a nitrogen atom or a CH group,and their acid addition salts and metal salt complexes are prepared as described and find use as fungicides.

Abstract: There are presented benzazepines of the formula ##STR1## wherein either R.sup.1 is hydrogen, lower alkyl, 4-pyridyl or the group --(CH.sub.2).sub.n --NR.sup.6 R.sup.7 and R.sup.2 and R.sup.3 together are an additional bond or R.sup.1 and R.sup.2 together are the oxo group and R.sup.3 is hydrogen or lower alkyl, R.sup.4 is phenyl, o-halophenyl or 2-pyridyl, R.sup.5 is halogen or nitro and either R.sup.6 is hydrogen or lower alkyl and R.sup.7 is hydrogen, lower alkyl, lower alkenyl or lower alkynyl or R.sup.6 and R.sup.7 together with the nitrogen atom are 4-(lower alkyl)-1-piperazinyl or 4-morpholinyl and n is the number 0 or 1, and their pharmaceutically acceptable acid additions salts.The compounds possess interesting psychotropic properties, i.e., pronounced anxiolytic properties have been established in the case of certain representative members of this class of substance.

Abstract: Novel 4-phenyl-1,3-benzodiazepines, novel intermediates thereof, and methods of preparing same are described. These benzodiazepines are useful as antidepressants, analgetics and anticonvulsants.

Abstract: Compounds of the formula (I) ##STR1## wherein; n is 1 to 5Y is --CH.sub.2 --CH.sub.2 or --CH.dbd.CH--;R.sub.1 is hydrogen or CO.sub.2 R.sub.1 represents an ester group in which the R.sub.1 moiety contains from 1-12 carbon atoms;R.sub.2 is hydrogen, C.sub.1-4 alkyl, or phenyl;R.sub.3 is hydroxy or protected hydroxy;R.sub.4 is hydrogen, C.sub.1-9 alkyl, C.sub.3-8 cycloalkyl, C.sub.3-8 cycloalkyl-C.sub.1-6 alkyl, phenyl, phenyl -C.sub.1-6 alkyl, naphthyl, naphthyl C.sub.1-6 alkyl, any of which phenyl moieties or naphthyl moieties may be substituted by one or more halogen trifluoromethyl, C.sub.1-6 alkyl, hydroxy, C.sub.1-6 alkoxy, phenyl C.sub.1-6 alkoxy or nitro groups;R.sub.5 is hydrogen, C.sub.1-6 alkyl, C.sub.5-8 cycloalkyl, phenyl, phenyl-C.sub.1-6 alkyl or phenyl C.sub.3-6 cycloalkyl, any of which phenyl moieties may be substituted by one or more halogen, trifluoromethyl, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or nitro groups; orR.sub.2 and R.sub.

Abstract: New acyl-1H-1,2,4-triazole derivatives of the formula ##STR1## wherein R may be located on one of the two adjacent nitrogen atoms and may represent hydrogen; a group R.sub.5 -CO wherein R.sub.5 is selected from (C.sub.1-4)alkyl, (C.sub.2-4)alkenyl, (C.sub.2-4)alkynyl, phenyl, phenyl substituted by one to three groups independently selected from halo, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, trifluoromethyl, cyano, nitro, amino, di-(C.sub.1-4)alkylamino, (C.sub.2-4)acylamino and methylenedioxy, benzyl, cinnamyl, amino, (C.sub.1-4)alkylamino, di-(C.sub.1 -C.sub.4)alkylamino, phenylamino, phenylamino wherein the phenyl ring may be substituted by one to three groups independently selected from halo, (C.sub.1-4)alkyl, (C.sub.1-4)alkoxy, trifluoromethyl, cyano, nitro, amino, di-(C.sub.1-4)alkylamino, (C.sub.2-4)acylamino and methylenedioxy, halo(C.sub.1-4)alkyl, (C.sub.1-4)alkoxy and benzyloxy;a group R.sub.6 -SO.sub.2 wherein R.sub.6 may represent (C.sub.

Abstract: Novel 4-phenyl-1,3-benzodiazepines, novel intermediates thereof, and methods of preparing same are described. These benzodiazepines are useful as antidepressants, analgetics and anticonvulsants.

Abstract: Novel 4-phenyl-1,3-benzodiazepines, novel intermediates thereof, and methods of preparing same are described. These benzodiazepines are useful as antidepressants, analgetics and anticonvulsants.

Abstract: The invention provides novel N-amino-2-oxo-3-oxazo-lidine derivatives, e.g. 2-methoxy-N-(2,6-dimethylphenyl)-N-(2-oxo-3-oxazolidinyl)-acetamide, which are useful as fungicides. Other objects of the invention are fungicidal compositions comprising such novel compounds and methods of combating phytopathogenic fungi in plants, seeds or soil with the aid of said novel compounds.

Abstract: Azole compounds of the formula ##STR1## where X is hydrogen, halogen or trifluoromethyl, m is an integer from 1 to 5, Z is N or CH, R.sup.1 is C.sub.2 -C.sub.4 -alkenyl or C.sub.2 -C.sub.4 -alkynyl, and R.sup.2 is hydrogen, C.sub.1 -C.sub.4 -alkyl, C.sub.2 -C.sub.4 -alkenyl, C.sub.2 -C.sub.4 -alkynyl or C.sub.2 -C.sub.4 -alkanoyl, and their crop-tolerated addition salts with acids, and metal complexes, as well as fungicides which contain these compounds.

Abstract: New halo-methyl-thioamino-benzamides of the formula ##STR1## wherein X.sup.1 represents optionally substituted alkylene, arylene or alkarylene, it being possible for the alkylene and/or arylene and/or alkarylene groups to be linked via oxo, thio, carboxo, carboxamido or sulphoxo groups,A.sup.1 denotes the radical ##STR2## wherein Hal represents halogen,the various substituents R can be identical or different and represent hydrogen, optionally substituted alkyl or aryl or a substituted R, in the case where X.sup.1 denotes optionally substituted ethylene and m.sup.1 and n.sup.1 represent the number 1, forms an ethylene bridge by being linked to a second R,m.sup.1 denotes an integer from 1 to 5 and indicates the number of linkages of ##STR3## with X.sup.1, and n.sup.1 denotes a number from 1 to 100;a process for preparing the same by reaction of a halo-methyl-thioamino-benzoic acid fluoride with an amine in the presence of a base and the use of such halo-methyl-thioamino-benzamides as microbicidal agents.

Abstract: Compounds of the formula (I): ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.1 is hydrogen or C.sub.1-6 alkyl, and R.sub.2 is hydroxy, C.sub.1-4 alkylsulphonyloxy or p-toluenesulphonyloxy are useful for the prophylaxis and treatment of diseases due to allergic response in mammals. Processes for their preparation are described.

Abstract: The 4(3H)-quinazolinone compounds of the formula (I) ##STR1## wherein R.sub.1 and R.sub.3, independently from each other, represent a lower alkyl group;R.sub.2 represents a lower alkoxycarbonyl group;Q represents a phenyl group or a substituted phenyl group substituted by at least one member selected from the group consisting of halogen atoms, lower alkyl groups, lower alkoxy groups, di(lower)-alkylamino groups, a methylenedioxy group, a trifluoromethyl group, a hydroxyl group, and a nitro group;R.sub.4 represents a hydrogen atom or a lower alkyl group;R.sub.

Abstract: N-substituted fluoroaziridines useful as chemical intermediates and process or making by reaction of fluoroazines with fluorocarbenes.