Patents Examined by Ba K. Trinh
  • Patent number: 6800768
    Abstract: Novel coumarin derivatives comprising a coumarin moiety linked to a non-nucleosidic backbone moiety are disclosed. The resulting molecules are typically used as photoactivate crosslinking groups when incorporated into polynucleotides as replacements for one or more of the complementary nucleoside bases present in probes used in procedures involving nucleic acid hybridization reactions.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: October 5, 2004
    Assignee: Naxcor, Inc.
    Inventors: Peter C. Cheng, Tadashi J. Mizoguchi
  • Patent number: 6797833
    Abstract: Taxane derivatives having alternative C9 substituents.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: September 28, 2004
    Assignee: Florida State University
    Inventors: Robert A. Holton, Ki-byung Chai, Yukio Suzuki
  • Patent number: 6797832
    Abstract: The present invention provides a method of producing 5-oxy-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ester economically, industrially advantageously and efficiently in a large amount. The present invention is a method of producing 5-oxy-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ester (X), which is shown in the following scheme. wherein each symbol is as defined in the specification.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: September 28, 2004
    Assignees: Sagami Chemical Research Center, Kuraray Co., Ltd.
    Inventors: Shiro Terashima, Katsuji Ujita, Tomoya Kuwayama, Takashi Sugioka, Kazuya Shimizu, Koichi Kanehira
  • Patent number: 6794523
    Abstract: Taxane derivatives having an alkoxy, alkenoxy or aryloxy substituted C13 side chain.
    Type: Grant
    Filed: September 17, 2002
    Date of Patent: September 21, 2004
    Assignee: Florida State University
    Inventors: Robert A. Holton, Ki-byung Chai, Hamid Idmoumaz, Hossain Nadizadeh, Kasthuri Rengan, Yukio Suzuki, Chunlin Tao
  • Patent number: 6794535
    Abstract: Process for the production of lower aliphatic esters comprising reacting a lower olefin with a saturated lower aliphatic monocarboxylic acid in the vapor phase in the presence of a heteropolyacid catalyst. The reaction is carried out in a plurality of reactors set up in series, and the feedstock is rendered substantially free of metallic or metal compound impurities prior to being brought into contact with the heteropolyacid catalyst.
    Type: Grant
    Filed: January 3, 2001
    Date of Patent: September 21, 2004
    Assignee: BP Chemicals Limited
    Inventors: Simon Frederick Thomas Froom, Stephen Robert Hodge, Witold Franciszek Pacynko
  • Patent number: 6790970
    Abstract: The present invention provides a novel (meth)acrylic acid ester compound useful as a resin material for photosensitive compositions, which enables control of the molecular weight of a resin to be prepared. The novel (meth)acrylic acid ester compound is one represented by the following formula (I): wherein R1 and R2 each independently represent a hydrogen atom or a hydroxyl group; and R3 represents a hydrogen atom or a methyl group.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: September 14, 2004
    Assignee: Fuji Photo Film Co., Ltd.
    Inventors: Kenichiro Sato, Toshiaki Aoai
  • Patent number: 6790969
    Abstract: A process for regenerating a zeolite catalyst comprises thermal treatment of the catalyst at above 120° C. in the presence of a gas stream comprising hydrogen.
    Type: Grant
    Filed: March 4, 2003
    Date of Patent: September 14, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Ulrich Müller, Joaquim Henrique Teles, Anne Wenzel, Wolfgang Harder, Peter Rudolf, Alwin Rehfinger, Peter Ba&bgr;ler, Norbert Rieber
  • Patent number: 6790986
    Abstract: Gabapentin free from mineral acids anions is obtained by precipitating from a gabapentin aqueous solution a corresponding hydroxybenzoate, from which pure gabapentin is subsequently obtained by dissolution in a lower alcohol and treatment with a tertiary base.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: September 14, 2004
    Assignee: Farchemia S.r.l.
    Inventors: Gabriele Breviglieri, Sergio Contrini, Cinzia Assanelli
  • Patent number: 6790987
    Abstract: The present invention relates to a process of cleaving lactones optionally having functional groups to give carboxylic acids, where the corresponding lactone is reacted with hydrogen with catalysis by a compound of a metal of group VIII of the Periodic Table of the Elements which has been modified with organophosphines. The process is preferably carried out in a two-phase system using catalysts which have water-soluble phosphine ligands. The reaction is particularly suitable for cleavage 2-ethylidene-6-hepten-5-olide to give ethylidene-6-heptenecarboxylic acid or isomers thereof. This carboxylic acid can be hydrogenated in a manner known per se to give 2-ethylheptanoic acid.
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: September 14, 2004
    Assignee: BASF Aktiengesellschaft
    Inventors: Arno Behr, Volker Brehme
  • Patent number: 6790988
    Abstract: A catalyst comprising a promoted mixed metal oxide is useful for the vapor phase oxidation of an alkane or a mixture of an alkane and an alkene to an unsaturated carboxylic acid and for the vapor phase ammoxidation of an alkane or a mixture of an alkane and an alkene to an unsaturated nitrile.
    Type: Grant
    Filed: May 7, 2003
    Date of Patent: September 14, 2004
    Assignee: Rohm and Haas Company
    Inventors: Sanjay Chaturvedi, Anne Mae Gaffney, Scott Han, Michele Doreen Heffner, Ruozhi Song
  • Patent number: 6787657
    Abstract: An optically active epoxypropionate derivative of the following formula (1): wherein symbol * represents optically active carbon. Also disclosed is an optically active epoxypropionate derivative of the following formula (2): wherein symbol * represents optically active carbon.
    Type: Grant
    Filed: February 21, 2001
    Date of Patent: September 7, 2004
    Assignee: Tosoh Corporation
    Inventors: Akinori Tanaka, Takumi Kagawa
  • Patent number: 6787655
    Abstract: One aspect of the present invention relates to methods for the transition-metal-catalyzed asymmetric 1,4-addition of a nucleophile, e.g., hydride, to cyclic and acyclic enoates and enones. In certain embodiments of the methods of the present invention, the transition metal catalyst consists essentially of copper and an asymmetric bidentate bisphosphine ligand.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: September 7, 2004
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen L. Buchwald, Daniel H. Appella, Yasunori Moritani, Ryo Shintani, Valdas Jurkauskas
  • Patent number: 6784304
    Abstract: Novel oxazolidines finding utility as intermediates in the preparation of C-13 acyloxy sidechain-bearing taxanes such as paclitaxel and analogs thereof. The present invention also relates to novel methods of coupling the oxazolidines to form the aforementioned taxanes, and to methods of preparing the oxazolidines.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: August 31, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: John K. Thottathil, Ivan D. Trifunovich
  • Patent number: 6784300
    Abstract: Disclosed is a holographic recording medium. The novel holographic recording mediums disclosed herein comprises: a) at least one polyfunctional epoxide monomer or oligomer which undergoes acid initiated cationic polymerization. Each epoxide in the monomer or oligomer is linked by group comprising a siloxane to a silicon atom and each monomer or oligomer has an epoxy equivalent weight of greater than about 300 grams/mole epoxide; b) a binder which is capable of supporting cationic polymerization; c) an acid generator capable of producing an acid upon exposure to actinic radiation; and optionally d) a sensitizer.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: August 31, 2004
    Assignee: Aprilis, Inc.
    Inventors: Erdem A. Cetin, Richard A. Minns, David A. Waldman
  • Patent number: 6781013
    Abstract: A process is provided which can effectively inhibit occurrence of hot spots in reaction zones or heat accumulation at the hot spots, in the occasion of producing acrolein and acrylic acid through vapor phase oxidation of propylene in the presence of a catalyst using a fixed bed shell-and-tube reactor, said catalyst having a composition represented by a general formula (1): MoaWbBicFedAeBfCgDhEiOx (wherein A is at least an element selected from Co and Ni; B is at least an element selected from P, Te, As, B, Sb, Sn, Ce, Nb, Pb, Cr, Mn and Zn; C is alkali metal element; D is alkaline earth metal element; E is at least an element selected from Si, Al, Ti and Zr; and O is oxygen; a, b, c, d, e, f, g, h, i and x denote the atomic numbers of Mo, W, Bi, Fe, A, B, C, D, E and O, respectively, and where a is 12, b is 0-5, c is 0.1-10, d is 0.1-10, e is 1-20, fis 0-5, g is 0.001-3, h is 0-3, i is 0-30, and x is a numerical value which is determined depending on the extent of oxidation of each of the elements).
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: August 24, 2004
    Assignee: Nippon Shokubai Co., Ltd.
    Inventor: Michio Tanimoto
  • Patent number: 6780442
    Abstract: This invention includes both a one-column process and a two-column process for the preparation of compositions enriched for anthocyanins from a crude plant extract. Both processes include a novel column purification step using a brominated polystyrene resin. This invention also includes extracts enriched for anthocyanins.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: August 24, 2004
    Assignee: Hauser, Inc.
    Inventors: David T. Bailey, Delano R. Freeberg, Dennis Gertenbach, Gerald T. Gourdin, Steven L. Richheimer, Michael S. Tempesta, F. Joseph Daugherty
  • Patent number: 6780879
    Abstract: Taxanes having a carbonate substituent at C(7), a hydroxy substituent at C(10), and a range of C(2), C(9), C(14), and side chain substituents.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: August 24, 2004
    Assignee: FSU Research Foundation, Inc.
    Inventor: Robert A. Holton
  • Patent number: 6774250
    Abstract: The invention relates to the process for the preparation of liquid reaction products of cycloaliphatic epoxides with mono- or multifunctional hydroxy compounds. The process comprises reacting a polyfunctional cycloaliphatic epoxy resin with a mono- or multifunctional hydroxy compound in the presence of a heterogeneous surface-active catalyst. The invention also relates to curable compositions containing the product obtained by the process.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: August 10, 2004
    Assignee: Huntsman Advanced Materials Americas Inc.
    Inventors: Kevin B. Hatton, Pauline G. Barker, Claus W. Rabener, Christiane Rabener
  • Patent number: 6774259
    Abstract: A stereoselective process for the industrial synthesis of compounds of formula (I): wherein R represents linear or branched (C1-C6)alkyl, and application in the synthesis of perindopril and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: August 10, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Souvie, Alain Renaud
  • Patent number: 6774262
    Abstract: The invention provides a method of increasing the reaction rate of an organic synthesis reaction by utilizing supply of OH− from water in the absence of catalyst without adding a basic catalyst in supercritical water or subcritical water of at least 350 ° C., and a method of generating alcohol and carboxylic acid with high reaction rate by performing a Cannizzaro reaction in the absence of catalyst without adding a basic catalyst in supercritical water, and to a method of synthesis of alcohol and carboxylic acid from an aldehyde in the absence of catalyst without adding a basic catalyst near the critical point (375 to 380 ° C., 22.5 to 25 MPa) of supercritical water.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: August 10, 2004
    Assignee: Japan as represented by Secretary of Agency of Industrial Science and Technology
    Inventors: Yutaka Ikushima, Osamu Sato, Kiyotaka Hatakeda