Patents Examined by Donald B. Moyer
  • Preparation of vinyl chloride by thermal cracking of 1,2-dichloroethane
    Patent number: 4720599
    Abstract: A process for the preparation of vinyl chloride by vaporizing liquid 1,2-dichloroethane, thermally cracking the 1,2-dichloroethane and cooling the hot reaction mixture by means of cooled and condensed portions of the reaction mixture, wherein a defined amount of the 1,2-dichloroethane is taken off as liquid in or downstream of the vaporizer and mixed with a defined amount of the cooled liquid portion of the reaction mixture, the mixture is distilled and the constituents taken off the top of the distillation column are mixed with the liquid 1,2-dichloroethane upstream of the vaporizer while the constituents taken off the bottom of the distillation column are worked up by distillation.
    Type: Grant
    Filed: October 9, 1984
    Date of Patent: January 19, 1988
    Assignee: BASF Aktiengesellschaft
    Inventors: Werner Hebgen, Eckehard Danz, Gerd Krome, Erhard Stahnecker
  • Antagonists of slow reacting substances of anaphylaxis
    Patent number: 4717736
    Abstract: Compounds having the formula: ##STR1##are antagonists of leukotrienes of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory agents and cytoprotective agents.
    Type: Grant
    Filed: November 21, 1984
    Date of Patent: January 5, 1988
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Joshua Rokach, Robert N. Young
  • Preparation of aromatic iodine compounds
    Patent number: 4716254
    Abstract: Monohalobenzene compounds are iodinated with an iodination reagent selected from the group consisting of (i) iodine monochloride and (ii) I.sub.2 /Cl.sub.2 mixtures having a mol ratio of about 1:3-5:1, in the presence of a catalyst selected from the group consisting of MoCl.sub.5, FeCl.sub.3, lanthanide chlorides and mixtures thereof. Preferably one of chlorobenzene and fluorobenzene is at least partially converted to at least one of para-iodochlorobenzene and para-iodofluorobenzene. Various other aromatic compounds, preferably di- and trichlorobenzene, xylenes, nitrobenzene and ethyl benzoate, are iodinated with an iodination reagent selected from the group consisting of (i) iodine monochloride and (ii) I.sub.2 /Cl.sub.2 mixtures having a mol ratio of about 1:3-5:1, in the presence of a catalyst comprising FeCl.sub.3 and, optionally, a lanthanide chloride.
    Type: Grant
    Filed: July 7, 1986
    Date of Patent: December 29, 1987
    Assignee: Phillips Petroleum Company
    Inventor: Raymond L. Cobb
  • Process for the production of 1,2,3-trichloropropane
    Patent number: 4714792
    Abstract: 1,2,3-trichloropropane is prepared by reacting allyl chloride with sulfuryl chloride, in the presence of 1-10,000 ppm of a nitrogen-containing base, a phosphine or a phosphine oxide. Suitable nitrogen-containing bases include aliphatic, aromatic and heterocyclic amines, and mixtures thereof; suitable phosphines are preferably aliphatic or aromatic phosphines and suitable phosphine oxides are aliphatic or aromatic phosphine oxides.
    Type: Grant
    Filed: September 6, 1985
    Date of Patent: December 22, 1987
    Assignee: Huels Aktiengesellschaft
    Inventors: Dieter J. Muller, Heinrich Wehmeyer
  • Process for producing 2,6-naphthalene-dicarboxylic acid
    Patent number: 4709088
    Abstract: A process for producing 2,6-naphthalenedicarboxylic acid which comprises oxidizing 2,6-diisopropylnaphthalene or its oxidation product as a starting material with molecular oxygen in a reaction medium containing at least 50% by weight of an aliphatic monocarboxylic acid having not more than 3 carbon atoms in the presence of an oxidation catalyst comprising (A) at least one heavy metal element selected from the group consisting of cobalt and manganese, and (B) bromine element, the 2,6-diisopropylnaphthalene and/or its oxidation product being used in a proportion of 0.1 to 5 moles per gram-atom of the heavy metal element of the oxidation catalyst.
    Type: Grant
    Filed: July 15, 1986
    Date of Patent: November 24, 1987
    Assignee: Teijin Petrochemical Industries, Ltd.
    Inventors: Isao Hirose, Tamio Amemiya, Tokuji Sakai
  • Process for the preparation of compounds halogenated .alpha. to an electron-attracting group
    Patent number: 4705650
    Abstract: Compounds halogenated in the .alpha.-position to an electron-attracting group of formula ##STR1## in which X denotes a halogen atom, R denotes a hydrogen atom or a hydrocarbon radical or a radical --(CH.sub.2).sub.3 --COOR.sub.1 and Z denotes a radical --CHO, --COR.sub.2, --COOR.sub.3, --CONR.sub.4 R.sub.5, --CN, --SO.sub.2 R.sub.6, --NO.sub.2, --CO--(CH.sub.2)p--COO.sub.1 or --COO(CH.sub.2)p--COOR.sub.1 are made by a halogenating deacylation of a compound of formula ##STR2## in which R' denotes a hydrogen atom or a hydrocarbon radical, R" denotes a methyl radical and Z' denotes a radical --CHO, --COR.sub.2, --COOR.sub.3, --CONR.sub.4 R.sub.5, --CN, --SO.sub.2 R.sub.6 or --NO.sub.2 or R' and R" may form a radical --(CH.sub.2)-- or R' and R" may form a radical --CO--(CH.sub.2)p-- or --COO(CH.sub.2)p--, using an alkali metal alcoholate or an alkali or alkaline-earth metal carbonate and a halogenating agent.
    Type: Grant
    Filed: July 10, 1985
    Date of Patent: November 10, 1987
    Assignee: Rhone-Poulenc Sante
    Inventors: Gerard Mignani, Didier Morel
  • Vapor phase synthesis of hexafluoroisobutylene
    Patent number: 4705904
    Abstract: A vapor phase synthesis of hexafluoroisobutylene, which comprises contacting in the vapor phase in a catalyst zone, B, of a reactor hexafluoropropylene oxide with a fluorinated catalyst such as fluorinated silica-alumina at a temperature of about 400.degree.-600.degree. C. for a residence time sufficient to form a vapor stream comprising hexafluoroacetone which is thereafter directly contacted in a heating zone of the reactor with a vapor stream comprising a keytone-generating compound such as acetic anhydride at a temperature of about 500.degree.-700.degree. C. for a residence time sufficient to form a stream comprising hexafluoroisobutylene, substantially-free of perfluoroisobutylene and recovering the hexafluoroisobutylene product is disclosed.
    Type: Grant
    Filed: January 17, 1986
    Date of Patent: November 10, 1987
    Assignee: Allied Corporation
    Inventors: John H. Bonfield, Harry E. Ulmer
  • Process for the desulphurization of mercaptans
    Patent number: 4704481
    Abstract: Benzylic and aromatic mercaptans are desulphurized by contacting the mercaptan with carbon monoxide at elevated temperatures in the presence of an aqueous hydrocarbon and a cobalt carbonyl catalyst.
    Type: Grant
    Filed: January 6, 1986
    Date of Patent: November 3, 1987
    Assignee: The British Petroleum Company p.l.c.
    Inventors: Howard Alper, David J. H. Smith
  • Process of organic material extraction from bituminous sands or oil bearing sands
    Patent number: 4702487
    Abstract: This invention relates to an improved process for extraction organic material from bituminous sands or oil bearing sand, including: diluent slurrying in a conditioning drum; screening the slurry and directing it into one or two helical classifiers in counter-current with diluent, to obtain in the overflow the organic matter in solution with diluent; feeding the mineral matter, withdrawn from the classifiers, substantially free of bitumen or oil, but saturated with diluent, into a column where it settles towards the bottom through diluent and then through an aqueous medium, under and in direct contact with the diluent. Process control agents are added to the aqueous medium. Diluent and fresh water are continuously fed into the vessel.
    Type: Grant
    Filed: July 7, 1983
    Date of Patent: October 27, 1987
    Assignee: Institutul de Cercetari Si Poriectari Pentru Petrol Si Gaze
    Inventors: Anatol Stoian, Nicolita Panaitescu, Marioara Tuliu
  • L-aminodicarboxylic acid alkanes
    Patent number: 4701552
    Abstract: This invention relates to novel sweeteners of the formula: ##STR1## wherein A is hydrogen, alkyl containing 1-3 carbon atoms, hydroxyalkyl containing 1-3 carbon atoms, alkoxymethyl wherein the alkoxy contains 1-3 carbon atoms or --CO.sub.2 R in which R is alkyl containing 1-3 carbon atoms;A' is hydrogen or alkyl containing 1-3 carbon atoms;A and A' taken together with the carbon atom to which they are attached form cycloalkyl containing 3-4 carbon atoms;Y is --(CHR.sub.2).sub.n -R.sub.1 or --CHR.sub.3 R.sub.4 ;R.sub.1 is alkyl-substituted cycloalkyl, cycloalkenyl, bicycloalkyl or bicycloalkenyl containing at least one alkyl in the .beta.-position of the ring, up to 7 ring carbon atoms and up to a total of 12 carbon atoms;R.sub.2 is H or alkyl containing 1-4 carbon atoms;R.sub.3 and R.sub.4 are each cycloalkyl containing 3-4 ring carbon atoms;n=0 or 1; andm=0 or 1;and food-acceptable salts thereof.
    Type: Grant
    Filed: March 21, 1986
    Date of Patent: October 20, 1987
    Assignee: General Foods Corporation
    Inventors: Paul R. Zanno, Ronald E. Barnett, Glenn M. Roy
  • Process for preparing alkyl esters of methyltartronic acid
    Patent number: 4701550
    Abstract: There is described a process for preparing alkyl esters of methyltartronic acid by hydroxylation of methacrylic acid to alpha-methylglyceric acid with H.sub.2 O.sub.2, in an aqueous medium, in the presence of H.sub.2 WO.sub.4 and optionally of H.sub.3 PO.sub.4 or H.sub.3 AsO.sub.4 or alkaline salts thereof as catalysts, at pH<2 and at temperatures of from 50.degree. to 100.degree. C., by subsequent oxidation of alpha-methylglyceric acid to methyltartronic acid with HNO.sub.3 in excess or with O.sub.2, in an aqueous-alkaline medium, in the presence of Pd or Pt carried on carbon or oxides thereof as catalysts, at temperatures of 60.degree.-100.degree. C., and final esterification of methyltartronic acid with alcohols C.sub.1 -C.sub.4.
    Type: Grant
    Filed: June 17, 1985
    Date of Patent: October 20, 1987
    Assignee: Istituto Guido Donegani S.p.A.
    Inventors: Carlo Venturello, Enzo Alneri, Alfredo Coassolo, Rino D'Aloisio
  • Cyclized unsaturated keto acids
    Patent number: 4701553
    Abstract: Unsaturated cyclic keto acid may be prepared by cyclizing alken-2-yl dicarboxylic acid anhydride with Lewis acid catalyst in anhydrous Friedel-Craft solvent. Amides of these unsaturated cyclic keto acids useful as friction improvers in lubricating oils, may be prepared by reaction of an amine such as ethanolamine with an unsaturated cyclic keto acid.
    Type: Grant
    Filed: January 28, 1983
    Date of Patent: October 20, 1987
    Assignee: Texaco Inc., White
    Inventor: Justin C. Powell
  • Process for preparing trifluoroacetic or trichloroacetic acid esters
    Patent number: 4701551
    Abstract: A process for preparing trifluoroacetic or trichloroacetic acid esters, wherein trifluoroacetic or trichloroacetic acid is brought together with a non-perfluorinated alcohol in liquid hydrofluoric acid and wherein the ester obtained is separated by decantation. The trifluoroacetic or trichloroacetic acid esters are used as synthesis intermediates in the pharmaceutical or the plant-protection industry.
    Type: Grant
    Filed: July 21, 1986
    Date of Patent: October 20, 1987
    Assignee: Rhone-Poulenc Specialites Chimiques
    Inventors: Michel DesBois, Louis Amiet
  • Thioalkanoic acid esters of phenylalkanols
    Patent number: 4701548
    Abstract: Described are thioalkanoic acid esters of phenylalkanols defined according to the structure: ##STR1## wherein M represents an integer selected from the group consisting of 1, 2 or 3; N is 0, 1 or 2; R.sub.1 represents methyl or hydrogen and R.sub.2 represents methyl or hydrogen.
    Type: Grant
    Filed: August 8, 1986
    Date of Patent: October 20, 1987
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Alan O. Pittet, Ranya Muralidhara, Manfred H. Vock, Domenick Luccarelli, Jr., Kevin P. Miller, Charles Wiener
  • Preparation of calcium propionate
    Patent number: 4700000
    Abstract: Calcium propionate is prepared by passing a vaporous mixture of propionic acid and water into an aqueous solution containing calcium propionate and calcium hydroxide, with or without propionic acid.
    Type: Grant
    Filed: January 14, 1985
    Date of Patent: October 13, 1987
    Assignee: BASF Aktiengesellschaft
    Inventors: Dieter Merkel, Wolfgang Muehlthaler, Hans Diem, Guenther Matthias
  • Preparation of dibenzo[b,f]thiepin compounds
    Patent number: 4697037
    Abstract: The preparation of dibenzo[b,f]thiepin compounds by a process comprising the direct carboxylation of an ortho-toluyl-aryl sulfide to introduce a phenylacetic acid side chain is disclosed.
    Type: Grant
    Filed: October 11, 1985
    Date of Patent: September 29, 1987
    Assignee: Merck & Co., Inc.
    Inventor: Thomas R. Verhoeven
  • Aminoacrylic acid derivatives
    Patent number: 4695646
    Abstract: Aminoacrylic and derivatives of the formula ##STR1## in which R is alkyl,R.sup.1 is alkoxycarbonyl, andR.sup.2 is alkyl, cycloalkyl, amino, alkylamino or dialkylamino,and intermediates therefor. The compounds can be converted into antibacterially active known oxyquinolinecarboxylic acid derivatives.
    Type: Grant
    Filed: January 6, 1986
    Date of Patent: September 22, 1987
    Assignee: Bayer Aktiengesellschaft
    Inventors: Fritz Maurer, Klaus Grohe
  • Process for producing acyloxy aromatic carboxylic acids
    Patent number: 4692546
    Abstract: Acyloxy aromatic carboxylic acids, e.g., 4-acetoxybenzoic acid, are prepared by oxidizing with oxygen an acyloxy aromatic ketone, e.g., 4-acetoxyacetophenone in the presence of manganese cations and a lower-carboxylic acid anhydride as catalyst and a co-reductant or promoter. The acyloxy aromatic ketone may be prepared by acylating a hydroxy aromatic ketone, e.g., 4-hydroxyacetophenone, which has the effect of "masking" the hydroxyl group of the ketone in a manner necessary to effect the subsequent transition-metal catalyzed oxidation of the ketone to the acyloxy aromatic carboxylic acid.
    Type: Grant
    Filed: September 25, 1985
    Date of Patent: September 8, 1987
    Assignee: Celanese Corporation
    Inventor: Kenneth G. Davenport
  • Catalytic process for coupling telomers of chlorotrifluoroethylene
    Patent number: 4691067
    Abstract: A process for coupling two low molecular weight telomers of chlorotrifluoroethylene comprises reacting the telomers with hydrogen in the presence of an effective amount of a catalyst to form a coupled olefin. The catalyst comprises palladium, platinum, rhodium, ruthenium, Raney nickel, Raney cobalt, and mixtures thereof, either supported or unsupported. The olefin can be fluorinated using a suitable fluorinating agent, such as chlorine trifluoride, to form a saturated telomer.
    Type: Grant
    Filed: June 9, 1983
    Date of Patent: September 1, 1987
    Assignee: Occidental Chemical Corporation
    Inventor: Johny S. Ng
  • Chlorotrifluoroethylene telomerization process
    Patent number: 4691065
    Abstract: An improved process for preparaing telomers of chlorotrifluoroethylene comprises the solution telomerization reaction of chlorotrifluoroethylene with carbon tetrachloride in the presence of a catalytic amount of cupric chloride (CuCl.sub.2) and an iron reductant. Preferably, the solvent for the system comprises acetonitrile, and the telomerization is carried out under elevated pressure conditions and at a temperature in the range of from about 90.degree. C. to about 150.degree. C. The crude telomer prepared by this process can be fluorinated to produce a stabilized oil or grease.
    Type: Grant
    Filed: November 2, 1983
    Date of Patent: September 1, 1987
    Assignee: Occidental Chemical Corporation
    Inventor: Bobby F. Dannels