Abstract: Electrochemical fluorination of a thiophene-1,1-dioxide derivative of the formula ##STR1## produces the novel perfluorinated sulphonic acid fluoride of the formula ##STR2## in which X, Y and Z each independently is F, a perfluoroalkyl group having 1 to 8 C-atoms in which one or more CF.sub.2 groups may optionally be replaced by oxygen, the oxygen atoms being separated by at least one CF.sub.2 group, optionally perfluoroalkyl-substituted cycloperfluoroalkyl group having 5 to 12 C-atoms in which one or more CF.sub.2 groups may be replaced by oxygen, orX and Y together denote an optionally perfluoroalkyl-substituted cycloperfluoroalkyl group in which one or more CF.sub.2 groups may be replaced by oxygen,R.sub.f each independently is F or a perfluoroalkyl group having 1 to 3 C-atoms, andn and m each independently is 0 or 1.The products are useful as surface active agents.
Abstract: Compositions are disclosed which consist of appropriate quantities and types of glyceryl monostearate dissolved into appropriate quantities and types of vitamin E. Appropriate mixtures or solutions of glyceryl monostearate and vitamine E resemble Vaseline (petrolatum) and can be used as a substitute for Vaseline in all its areas of use. The result is hardened vitamin E (defined as a solution that contains over 50% vitamin E). The remainder of the solution contains glyeryl monostearate.A third compound such as jojoba oil may be added to the above compositions. Other types of vegetable, or seed oils have been considered as an additive to the above compositions, but are not strongly recommended because of the dangers that are associated with rancid oils. Jojoba oil is the only oil that is compatible with the above solution and resistant to oxidation. Vegetable and seed oils are compatible but they also turn rancid.
Abstract: Phenylphosphonous dichloride is prepared by the continuous reaction of monochlorobenzene, phosphorus trichloride, and elemental phosphorus at elevated pressures and temperatures.
Abstract: A compound, or pharmaceutically acceptable salt thereof, having the formula: ##STR1## wherein X is ##STR2## wherein R is C.sub.3 -C.sub.12 alkyl or aralkyl, branched or unbranched, unsubstituted aryl, haloaryl, or C.sub.3 -C.sub.22 alkenyl, branched or unbranched; wherein R.sub.1 is H, OH or OCH.sub.3, and wherein R.sub.2 is OH or H, at least one of R.sub.1 and R.sub.2 being OH or OCH.sub.3. These sulfonamides have analgesic and anti-irritant activity when administered to humans and lower animals.
Abstract: N,N'-Bis[4-[2,3,6,-tri-O-sulfo-4-O-(2,3,4,6-tetra-O-sulfo-.alpha.(and .beta.)-D-glucopyranosyl)-.alpha.(and .beta.)-D-glucopyranosylthio or sulfinyl or sulfonyl]phenyl]alkyldiamides and alkyldiamines, the cation salts thereof, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
Type:
Grant
Filed:
April 16, 1982
Date of Patent:
August 16, 1983
Assignee:
American Cyanamid Company
Inventors:
Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
Abstract: Long chain fatty alcohols can be removed from alkylpolysaccharide products in thin film evaporators to achieve fatty alcohol levels of less than about 2% without excessive discoloration of the alkylpolysaccharide.
Type:
Grant
Filed:
April 26, 1982
Date of Patent:
July 12, 1983
Assignee:
The Procter & Gamble Company
Inventors:
Mark H. K. Mao, Larry E. Miller, John M. Weeman
Abstract: A composition and process for producing pigmentation in hair and skin is disclosed which employs non-mutagenic compounds to duplicate naturally occurring biosynthetic colors. The composition for imparting golden coloration comprises as active ingredients a solution of a tyrosine derivative having a side chain with a substituted amine group in admixture with certain compounds having a reactive nitrogen moiety, and is topically applied in the presence of an oxidant. The composition for imparting a dark coloration comprises as active ingredients s solution of tyrosine derivative having a side chain free for indole formation in admixture with certain compounds having a reactive nitrogen moiety, and is topically applied in the presence of an oxidant. Mixtures of the two compositions may be applied to impart proportionate intermediate colors.
Abstract: Water-soluble keratin hydrolyzate having at least two mercapto groups in one molecule and having an average molecular weight of 2,000 to 20,000, suitable for cosmetic application to the hair, particularly as hair fixatives. The hydrolyzate is prepared by reducing keratin in an aqueous solution of a reducing agent under alkaline conditions and subjecting the resulting reduction product to enzymatic hydrolysis.
Abstract: Aromatic esters of carbamic acid derivatives, e.g., p-chlorophenyl-N-methyl carbamate, are prepared by reaction of the corresponding aromatic alcohol, e.g., p-chlorophenol, and monoisocyanate, e.g., methyl isocyanate, in the presence of a catalytic amount of a combination of a 4-aminopyridine catalyst, e.g., 4-dimethylaminopyridine, and pyridine or methyl substituted pyridines. The product is substantially pure, having less than 0.80 weight percent allophanate ester by-product, e.g., p-chlorophenyl-N,N'-dimethyl allophanate, and less than 0.50 weight percent unreacted aromatic alcohol, e.g., p-chlorophenol. The reaction is readily controlled and characterized by the substantial absence of reflux. The product can be retained in the liquid state at reaction temperature for extended periods of time without significantly increasing the level of allophanate ester by-product.
Abstract: This invention relates to improved cosmetic compositions. It has been found that cosmetic compositions can be improved by adding to the formula a non-saponifiable fraction of an animal or vegetable oil. An animal or vegetable oil may also be present in the cosmetic composition, in which case it is preferably present in an amount below the conventional quantity and the non-saponifiable fraction is present in an amount at least equal to the amount of non-saponifiable material which would be extracted from the omitted portion of the animal or vegetable oil.
Abstract: An antipruritic, astringent and anti-inflammatory composition is provided. The composition is useful in the treatment of hemorrhoid symptoms.
Type:
Grant
Filed:
August 17, 1981
Date of Patent:
May 17, 1983
Assignee:
Ortho Pharmaceutical Corporation
Inventors:
Darius D. Dubash, Leonard L. Kaplan, George A. Ziets
Abstract: The invention relates to cosmetics which increase the elasticity and tightness of the skin. The cosmetics of the invention contain as active agent an extract of sunflower (Helianthus annuus L.) stalks or stalk portions, together with conventional carriers, diluents and/or additives. These cosmetics are prepared according to the invention so that stalks of sunflower or portions of the stalk are extracted with a 1 to 20-fold amount of water or another solvent suitable for cosmetic purposes, the extract is separated from the solids, and the resulting solution is optionally homogenized with carriers, diluents and/or additives usable in the preparation of cosmetics.
Type:
Grant
Filed:
July 9, 1981
Date of Patent:
May 10, 1983
Inventors:
Margit Nedeczky nee Gardy, Gyorgy Kiraly
Abstract: This shaving composition comprises a water soluble polyethylene oxide polymer having a molecular weight of 400,000 or less, a tracking agent component, a preservative component, and an anti-caking component. This composition is solid in form and may be molded into a variety of shapes, some of which may be operably attached to a razor.
Abstract: The specification describes a hair setting composition comprising as an effective component polyethylene glycol having an average molecular weight of 6,000-30,000. It also describes a hair setting composition comprising as effective components the following ingredients: (A) polyethylene glycol having an average molecular weight of 6,000-30,000 and (B) a divalent or trivalent metal salt of pyrrolidonecarboxylic acid and/or a polyoxyalkylene-added silicone oil. Such hair setting compositions may be formulated into an aerosol type or lotion or pump spray type and facilitates long-lasting hair styling without damaging hair.
Abstract: An essential peel oil containing high concentrations of carotenoid pigments and organoleptic constituents may be produced from citrus fruits by a process of abrading the flavedo in small pieces with maximum rupture of peel oil sacs and chromoplasts, mixing the abraded flavedo with a suitable solid dehydrating agent, and pressing the mixture so-produced to express the highly colored oil.
Abstract: A water soluble extract from nonpathogenic aerobic corynebacteria such as Corynebacterium equi Ko-85 strain, the said water soluble extract having the following characteristics:(a) protein content: 3.9-5.5 mg/ml (on the basis of Bovine Serum Albumin),(b) sugar component: 0.41-0.52 mg/ml (on the basis of glucose),(c) nucleic acid like substance: optical density in 260 nm/280 nm (ratio) of 1.56-1.62, and(d) isoelectric point: 3.75-3.80.The extract possesses an anti-allergic effect, an anti-cancer effect, and an immunopotentiative effect and is particularly useful as an anti-allergic agent.
Abstract: The invention relates to compositions for hair dyeing which contain, as the oxidative dye-stuff, in a cosmetically acceptable medium, para-phenylenediamine and ortho-aminophenol, or their cosmetically acceptable salts, in a ratio para-phenylenediamine/ortho-aminophenol which is such that, after the addition of an equal volume of hydrogen peroxide of 20 volumes strength and application to the hair for 30 minutes, no Bandrowsky's base can be detected in the oxidizing dyeing composition.The compositions according to the invention make it possible to impart background colorations to the hair without the formation of Bandrowsky's base.
Type:
Grant
Filed:
July 8, 1980
Date of Patent:
January 25, 1983
Assignee:
L'Oreal
Inventors:
Andree Bugaut, Philippe Thouvenin, Jean Cotteret
Abstract: Skin conditioning compositions comprising an alkali metal phosphoric acid ester salt of a partial glyceride, silicone fluid, a long chain alkyl ester of a fatty acid, an emollient material, an emulsifier and water. The phosphated glyceride and the dimethicone fluid serve to provide greater retention of the conditioning composition on the skin.
Type:
Grant
Filed:
March 20, 1981
Date of Patent:
January 25, 1983
Assignee:
The Procter & Gamble Company
Inventors:
Carole N. Chapin, Gary R. Kelm, David L. Shelton
Abstract: A cosmetic facial preparation comprising aloe vera, cornstarch or cosmetic clay, albumin, allantoin, Vitamin A, Vitamin D.sub.2 and Vitamin E.
Abstract: This invention is directed to an improved method for the extraction of silymarin (silymarin I-IV), in which a large part of the oil is removed from the fruits of Silybum marianum by cold pressing, the compressed mass is broken up, the pressed residue in extracted with ethyl acetate and the ethyl acetate extract is evaporated and processed.
Type:
Grant
Filed:
May 26, 1981
Date of Patent:
January 11, 1983
Assignee:
Dr. Madaus & Co.
Inventors:
Rolf Madaus, Klaus Gorler, Werner Molls