Abstract: A computer aided diagnostic system according to the invention is characterized in that first sick portion detecting means for detecting a sick portion candidate based upon an image acquired by a first modality, second sick portion detecting means for detecting a sick portion candidate based upon an image related to the same region of interest of the same subject and acquired by a second modality different from the modality, detection result synthesizing means for comparing the results of detection by the first and second sick portion detecting means and correspondence displaying means for relating the position of the sick portion candidate detected by the first sick portion detecting means on an image analyzed by the second sick portion detecting means and displaying it and for relating the position of the sick portion candidate detected by the second sick portion detecting means on an image analyzed by the first sick portion detecting means and displaying it are provided.

Abstract: The portable sensor device is connected with the arterial pressure measurement catheter by way of a pressure hose. The electronic pressure sensor is accommodated in the sensor housing. The analog sensor signal is output to the patient monitor by way of a cable. Aside from the channel for the analog sensor signal, additional channels are provided for communication between sensor device and patient monitor. A bidirectional channel serves for writing to and querying the memory module, in which patient data, such as age, gender, height/weight, etc., can be stored. The three-way cock possesses the settings “M” (measurement operation) and “0” (calibration measurement), in which the contactor is brought into connection with the contact. The switching contact is transmitted to the patient monitor, which thereby automatically recognizes zeroing of the sensor.

Abstract: The use of power-efficient transmitters to establish acoustic wave energy having low undesirable harmonics is achieved by adjusting the transmitter output waveform to minimize the undesirable harmonics. In one embodiment, both the timing and slope of the waveform edges are adjusted to produce the desired output waveform having little or no second harmonics. In the embodiment, output waveform timing adjustments on the order of fractions of the system clock interval are provided. This then allows for very fine control of a coarsely produced waveform. In one embodiment, the user can select the fine tuning to match the transmitter output signal to a particular load transducer.

Abstract: The invention relates to a device for synchronizing a magnetic resonance unit with the cardiac rhythm of a patient, comprising a number of electrodes for leading off electrocardiogram signals from the body of the patient and an evaluation unit for determining a characteristic trigger time within a cardiac rhythm period of the patient from the electrocardiogram signals. In order to provide a device, which allows reliable determination of characteristic trigger times within the cardiac rhythm period of the patient even with elevated magnetic field strengths and which operates at least largely independently of external magnetic fields, it is proposed that the evaluation unit is designed to compare electrocardiogram signals obtained before and after the introduction of the patient into the magnetic resonance unit, in order to determine an enlargement of at least one characteristic of the electrocardiogram signals due to the magnetic field.

Abstract: A method of characterizing the pathological response of tissue to a treatment plan, including: obtaining a set of sequential morphology renderings of the tissue, wherein each rendering corresponds to a particular point in time during the treatment plan; generating a set of representative values of a biomechanical property of the tissue for the set of renderings, wherein each representative value is based on a corresponding rendering; determining a trend of the biomechanical property based on the set of representative values; and predicting response of the tissue to the treatment plan based on the trend of the biomechanical property.

Abstract: A 2D array transducer 10 is separated into a plurality of sub-arrays. Four representative sub-arrays from SA1 to SA4 are shown in an enlarged manner. In addition, the 2D array transducer (10) is segmented into a plurality of transducer regions. Four regions of (I)-(IV) segmented by dot-and-chain lines represent four transducer regions. For each sub-array, a delay process corresponding to the sub-array is executed based on a delay pattern defining an amount of delay for each of the plurality of transducer elements belonging to the sub-array. In this process, for each transducer region, a common delay pattern is set for the plurality of sub-arrays belonging to the transducer region. For example, because sub-arrays SA1 and SA2 belong to the same transducer region (IV), a common delay pattern is set for the sub-arrays SA1 and SA2.

Abstract: An optical coherence tomography rotation catheter comprises a catheter body and a tubular member that rotates around a longitudinal axis in the catheter body. An optical fiber extends along an interior of the tubular member and has an optical fiber distal end. A light reflecting member is distal of the optical fiber distal end and rotates around the longitudinal axis with the tubular member. The light reflecting member includes a light reflecting surface which is spaced from and faces the optical fiber distal end and which is inclined to reflect the light from the optical fiber in a radial direction at an angle with respect to the longitudinal axis. The light reflecting member has a diameter of at most about 0.25 mm. The light reflecting surface is polished and coated with a light reflecting film.

Abstract: An apparatus, method and system for classifying a shockwave is described, particularly for use in an Extracorporeal Shockwave Lithotripsy (SWL) system. The method for classifying a shockwave generated and directed towards a stone in an extracorporeal shockwave lithotripsy treatment comprises receiving an acoustic signal at a passive unfocused acoustic sensor, determining whether at least one characteristic of the received acoustic emissions exceeds a respective pre-determined threshold value, and classifying the shockwave as effective or ineffective in dependence upon said determination. A method for predicting the outcome of an SWL treatment is also described.

Abstract: There are provided a biological information imaging apparatus that can measure ultrasound generated from an optical absorber in a deep part of a subject living body with high sensitivity, and a method for analyzing biological information using the biological information imaging apparatus. The biological information imaging apparatus that detects ultrasound and images biological information, includes: a light source that irradiates the subject with light for generating ultrasound from an optical absorber existing in the subject; an ultrasound transmission unit that transmits focused ultrasound to a specific region where the optical absorber exists; and an ultrasound detection unit that detects an ultrasound synthesized signal due to interaction between ultrasound generated from the optical absorber that absorbs the light and the focused ultrasound transmitted to the specific region.

Abstract: Systems and methods for monitoring patients utilizing reflectance avoidance as well as other imaging modalities. Information regarding perfusion, oxygen saturation and oxygen availability, as well as others may be obtained. System embodiments may include a light source, a light transport body configured to project light from the light source to an examination substrate and transmit light reflected by the examination substrate, and an analysis section in optical communication with the light transport body. The light source may be pulsed in order to improve the quality of video images produced by the systems.

Abstract: A plurality of sets of volume data, each of which represent the state of a beating heart in different phases, are obtained. Coronary artery regions are extracted from at least two sets of volume data from among the obtained sets of volume data. A plurality of analysis points are set in each extracted coronary artery region. Correlations are established among analysis points set at the same anatomical positions within the coronary artery regions. Index values that indicate the character of plaque are calculated at each analysis point within all of the coronary artery regions. The character of plaque is evaluated at positions within the coronary artery regions, by integrating the index values calculated at the analysis points corresponding to each of the positions. The evaluation results regarding the character of plaque at each of the positions within the coronary artery regions are output, correlated with information regarding the positions.

Abstract: Catheter-based Optical Coherence Tomography (OCT) systems utilizing an optical fiber that is positioned off-axis of the central longitudinal axis of the catheter have many advantage over catheter-based OCT systems, particularly those having centrally-positioned optical fibers or fibers that rotate independently of the elongate body of the catheter. An OCT system having an off-axis optical fiber for visualizing the inside of a body lumen may be rotated with the body of the elongate catheter, relative to a handle portion. The handle may include a fiber management pathway for the optical fiber that permits the off-axis optical fiber to rotate with the catheter body relative to the handle. The system may also include optical processing elements adapted to prepare and process the OCT image collected by the off-axis catheter systems described herein.

Abstract: A method and apparatus for scanning control and displaying an image in a magnetic resonance scanning chamber are disclosed. An apparatus includes a magnetic resonance imaging system, a scanning chamber computer, an operating chamber computer, and a communication connection device; the scanning chamber computer and the magnet are disposed in the scanning chamber together; the operating chamber computer is disposed in the operating chamber; the scanning chamber computer and the operating chamber computer are connected via the communication connection device.

Abstract: A technique for measuring thoracic vertebral bone density (BMD) and coronary calcium score (CCS). Representatively, BMD was measured and averaged at three consecutive thoracic spines (3T) starting from the left main coronary artery caudally and averaging the results of the measurements at the first, second and third spine regions to obtain a thoracic trabecular bone mineral density measurement. The “reference”, as the 3T BMD value of 30 year old and the piBMD (predicted individual BMD (piBMD) were developed. Based on the “reference”, and piBMD, T and Z score of 3T formula were derived in both genders. The new calibration phantom of TQCT and LQCT was designed. The ratios of CTHU/mg/cc were obtained with varying scanners, which were used to translate the CTHU to density units (mg/cc) in BMD and CCS mass measurement. A processor capable of quantitating both BMD and CCS burden was designed. In image without a calibration phantom, formulas were created to quantitate BMD with a high precision.

Abstract: A system for determining a location of an electrode of a medical device (e.g., a catheter) in a body of a patient includes a localization block for producing an uncompensated electrode location, a motion compensation block for producing a compensation signal (i.e., for respiration, cardiac, etc.), and a mechanism for subtracting the compensation signal from the uncompensated electrode location. The result is a corrected electrode location substantially free of respiration and cardiac artifacts. The motion compensation block includes a dynamic adaptation feature which accounts for changes in a patient's respiration patterns as well as intentional movements of the medical device to different locations within the patient's body. The system further includes an automatic compensation gain control which suppresses compensation when certain conditions, such as noise or sudden patch impedance changes, are detected.

Abstract: A method is disclosed for visualizing a lymph node in a volume section of an examination subject by way of a combined MR/PET apparatus and to a correspondingly embodied combined MR/PET apparatus. The method includes acquisition of PET data of the volume section by way of a positron emission detector in order to record on the basis of the PET data a metabolic activity per PET voxel within the predetermined volume section; acquisition of MR data of the volume section by way of a magnetic resonance system in order to record on the basis of the MR data a lymph-node-specific contrast per region of the predetermined volume section; and generation of an image as a function of the metabolic activity recorded per PET voxel and as a function of the lymph-node-specific contrast recorded per region, abnormal lymph nodes being visualized in the image as distinguishable from normal lymph nodes.

Abstract: An ultrasonic diagnostic imaging system produces an image with an extended focal range by transmitting a plurality of beams spaced along an array for multiline reception. The receive multilines of a plurality of transmit beams are spatially aligned and are combined with phase adjustment between the respective receive multilines to prevent undesired phase cancellation. The combined multilines produce the effect of an extended transmit focus so that an image produced using the combined multilines exhibits an extended focal range. To prevent motion artifacts the multiline order is adjustable as a function of image motion.

Abstract: Devices, systems, and methods for controlling the field of view in imaging systems are provided. For example, in one embodiment an imaging system includes a flexible elongate member sized and shaped for use within an internal structure of a patient, an imaging transducer positioned within the distal portion of the flexible elongate member, an imaging marker positioned to be detectable within a field of view of the imaging transducer, and a controller in communication with the flexible elongate member and configured to adjust a control signal of the flexible elongate member based on the detection of the imaging marker in data received from the flexible elongate member in order to achieve a desired field of view for the imaging transducer.

Abstract: A light source for a surgical system includes a broadband light source operable to produce broadband light. The light source further includes a wavelength splitter adapted to split the broadband light into illumination light having a spectral range covering at least a majority of the visible spectrum and surgical light having a spectral range outside of the spectral range of the illumination light. The light source then includes at least one surgical module adapted to control application of the surgical light. The light source also includes first and second coupling optics. The first coupling optics are configured to optically couple the illumination light to an illumination light guide for delivery to a first surgical probe. The second coupling optics are configured to optically couple the surgical light to a surgical light guide for delivery to a second surgical probe.

Abstract: Devices, systems, and methods for controlling the field of view in imaging systems are provided. For example, in one embodiment an imaging system includes a flexible elongate member sized and shaped for use within an internal structure of a patient, an imaging transducer positioned within the distal portion of the flexible elongate member, an imaging marker positioned to be detectable within a field of view of the imaging transducer, and a controller in communication with the flexible elongate member and configured to adjust a control signal of the flexible elongate member based on the detection of the imaging marker in data received from the flexible elongate member in order to achieve a desired field of view for the imaging transducer.