Patents Examined by Lewis Gotts
  • Patent number: 4039313
    Abstract: 4-CHLOROBENZYL-N,N-hexamethylenethiolcarbamate has been found to be uniquely active and selective in the control of weeds, particularly in crop cultivations such as rice paddies.
    Type: Grant
    Filed: June 24, 1974
    Date of Patent: August 2, 1977
    Assignee: Bayer Aktiengesellschaft
    Inventors: Masahiro Aya, Masao Miyamoto, Nobuo Fukazawa
  • Patent number: 4038386
    Abstract: Compounds are prepared of the formula ##STR1## The compounds of the invention possess valuable pharmacodynamic properties. They especially have a positive inotropic effect which is particularly noted in oral or enteral application. In contrast to the known compounds the compounds of the invention have more favorable pharmacological or pharmaceutical properties.
    Type: Grant
    Filed: April 3, 1975
    Date of Patent: July 26, 1977
    Assignee: Deutsch Gold- und Silber-Scheideanstalt Vormals Roessler
    Inventors: Otto Isaac, Klaus Posselt, Horst Uthemann
  • Patent number: 4036227
    Abstract: An osmotic device for releasing a useful agent at different release rate patterns from the device in a selected environment is disclosed. The device is comprised of a wall surrounding and forming a compartment as a means for containing a useful agent and having a passageway for releasing the agent. The wall is comprised in at least a part of a material permeable to an external fluid and impermeable to the agent. A layer of a pattern rate controlling material that erodes in a selected environment for changing the release rate pattern of the device is carried on the semipermeable wall distant from the compartment. The agent is soluble in the fluid and exhibits an osmotic pressure gradient across the semipermeable wall against the fluid, or the agent has limited solubility and is admixed with an osmotically effective solute soluble in the fluid that exhibits an osmotic pressure gradient across the semipermeable wall against the fluid.
    Type: Grant
    Filed: December 23, 1974
    Date of Patent: July 19, 1977
    Assignee: Alza Corporation
    Inventors: Alejandro Zaffaroni, Alan S. Michaels, Felix Theeuwes
  • Patent number: 4036949
    Abstract: Visually clear dentifrice comprising a water-insoluble aluminosilicate sodium salt complex in which the proportion of alumina is up to 3.3% by weight and in which the mole ratio of silica to alumina is at least about 45:1, as a polishing agent having a refractive index of about 1.44-1.47 and a gel vehicle for said polishing agent having about the same refractive index as said polishing agent, said polishing agent being substantially invisible in said gel vehicle.
    Type: Grant
    Filed: September 8, 1975
    Date of Patent: July 19, 1977
    Assignee: Colgate-Palmolive Company
    Inventor: Daniel Colodney
  • Patent number: 4036852
    Abstract: The process of the invention is directed to separating a racemic mixture of L- and D-phenyl-glycine amide, by treatments of the racemate with an optically active form of 2-pyrrolidone-5-carboxylic acid.
    Type: Grant
    Filed: October 20, 1975
    Date of Patent: July 19, 1977
    Assignee: Stamicarbon B.V.
    Inventor: Wilhelmus H. J. Boesten
  • Patent number: 4036990
    Abstract: The rate of solubility of a material of low solubility is increased by mixing the material with beta-1, 4-glucan and pulverizing the mixture. This simultaneously pulverizing both ingredients is found to produce a substantially different effect than when the ingredients are separately pulverized and then mixed together.
    Type: Grant
    Filed: March 12, 1975
    Date of Patent: July 19, 1977
    Assignee: FMC Corporation
    Inventors: Yoshinobu Nakai, Shin'Ichiro Nakajima, Kiyoshi Sugiyama
  • Patent number: 4035177
    Abstract: Certain N-thiolcarbonyl derivatives of N-phosphonomethylglycine are novel chemical compounds having desirable herbicidal activity.
    Type: Grant
    Filed: July 16, 1976
    Date of Patent: July 12, 1977
    Assignee: Monsanto Company
    Inventor: Van R. Gaertner
  • Patent number: 4033750
    Abstract: Mixture of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.3 are hydrogen or methyl group,R.sub.2 is lower alkyl group;And S-ethyl hexahydro-1H-azepine-1-carbothioate have greater herbicidal activity.
    Type: Grant
    Filed: September 4, 1975
    Date of Patent: July 5, 1977
    Assignee: Nippon Soda Company Limited
    Inventors: Hideo Hosaka, Hiromi Yoneda
  • Patent number: 4034076
    Abstract: This invention relates to a process for inhibiting the swelling of aluminium tubes containing toothpastes comprising alumina trihydrate, in which process there is incorporated in the toothpaste a silica sol of which the silica particles are negatively charged.
    Type: Grant
    Filed: March 3, 1975
    Date of Patent: July 5, 1977
    Assignee: Lever Brothers Company
    Inventors: James Coulson, Malcolm Richard Nearn
  • Patent number: 4032627
    Abstract: A tooth whitening cosmetic composition of the type applied temporarily to the dry tooth surface and removable by solvent. The cosmetic composition is characterized by its lustrous white appearance, extended wearing time, thicker viscosity and ease of removal with solvent.
    Type: Grant
    Filed: August 6, 1975
    Date of Patent: June 28, 1977
    Assignee: Koh-I-Noor Rapidograph, Inc.
    Inventors: Joseph T. Suchan, Vincent A. Burell
  • Patent number: 4031126
    Abstract: Dialkyl peroxydicarbonates are prepared in aqueous reaction media, washed with water, and then dried with sodium sulfate, calcium chloride, or the like. Peroxydicarbonates, particularly heat-sensitive peroxydicarbonates, may be dried safely and more effectively with the use of molecular sieves by contacting substantially phase water free peroxydicarbonate with sieves. Contact between heat-sensitive peroxydicarbonate and sieves should be effected in a way that avoids abrupt, excessive warming of peroxydicarbonate.
    Type: Grant
    Filed: February 12, 1976
    Date of Patent: June 21, 1977
    Assignee: PPG Industries, Inc.
    Inventor: James A. Manner
  • Patent number: 4030907
    Abstract: An algaecide composition having an improved ability to withstand photodecomposition comprising an aqueous solution containing a complex of a copper salt with an alkanolamine and an ammonium compound.
    Type: Grant
    Filed: June 12, 1974
    Date of Patent: June 21, 1977
    Assignee: Thompson-Hayward Chemical Co.
    Inventor: Lester Ray McNall
  • Patent number: 4029493
    Abstract: Phenoxybenzonitriles, halo-substituted on the phenoxy ring and halo- or alkyl-substituted on the benzonitrile ring ortho to the para-cyano position, form a new class of herbicides. These substituted phenoxybenzonitriles and herbicidal compositions containing them are highly effective as pre-emergence and post-emergence herbicides, especially at low use concentrations. They are highly effective against Crabgrass, Yellow Foxtail grass and Barnyard grass, annual grass weeds which reproduce by seed. They are also highly effective against Johnson grass, a perennial grass weed which reproduces by seed and underground rhizomes, and Pigweed, an annular broadleaf weed which reproduces by seed.
    Type: Grant
    Filed: May 21, 1975
    Date of Patent: June 14, 1977
    Assignee: Mobil Oil Corporation
    Inventor: Robert James Theissen
  • Patent number: 4029668
    Abstract: The invention relates to novel cyclopenteno[b]pyridine derivatives which have a group X on the 7-position and related tricyclic compounds. X is CONHR.sup.3, or CO.sub.2 R.sup.5 wherein R.sup.3 is hydrogen or lower alkyl and R.sup.5 is hydrogen or a lower alkyl or lower aralkyl group which may be substituted by alkyl, alkoxy, halogen, nitro or trifluoromethyl; other substituents may be present. The compounds are intermediates for compounds wherein X is CSNHR.sup.3 which are anti-ulcer agents.
    Type: Grant
    Filed: October 20, 1975
    Date of Patent: June 14, 1977
    Assignee: John Wyeth & Brother Limited
    Inventors: Adrian Charles Ward Curran, Roger Crossley, David George Hill
  • Patent number: 4029760
    Abstract: There are described pharmaceutical compositions useful for the treatment of gingivitis. Such a composition contains, as active ingredient from 0.5 to 25% by weight of at least one carraghenin in combination with a suitable vehicle. The compositions, which may contain various auxiliary components, can be in the form of toothpaste, mouthwash and like products. Even a short, but regular, use of a toothpaste containing the aforesaid composition results in a substantial improvement of gums and dental surfaces.
    Type: Grant
    Filed: March 11, 1975
    Date of Patent: June 14, 1977
    Assignee: Agence Nationale de Valorisation de la Recherche (ANVAR)
    Inventors: Yannick De Roeck born Holtzhauer, Herve De Roeck
  • Patent number: 4029883
    Abstract: Dehydroxylation of aminoglycoside antibiotics is carried out by halogenation of phosphorylated aminoglycoside antibiotics followed by reduction of thus halogenated antibiotics. The dehydroxylation process is entirely new and gives the final product in a high yield. The resulting deoxyaminoglycoside antibiotics are effective against microorganisms including aminoglycoside antiobiotics-resistant microorganisms.
    Type: Grant
    Filed: December 20, 1973
    Date of Patent: June 14, 1977
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Kentaro Hiraga, Tetsuya Okutani, Kouichi Yoshioka, Tsunehiko Asako
  • Patent number: 4029880
    Abstract: Radio-iodine derivatives of digoxin and digitoxin are provided having the formula IV, whereR is H or lower alkyln is 1, 2 or 3Y is H or carboxylm is 0 to 5, andQ is a phenolic or imidazole ring,To which radio-iodine atoms are attached. Novel intermediates in the preparation of the radio-iodine derivative are described. The derivatives are useful for the radioimmunoassay of digoxin and digitoxin.
    Type: Grant
    Filed: June 19, 1975
    Date of Patent: June 14, 1977
    Assignee: The Radiochemical Centre Limited
    Inventors: Keith Charles Tovey, John William Addison Findlay
  • Patent number: 4028092
    Abstract: Novel substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio- phenyl ureas and certain novel intermediates are provided. The compounds of the instant invention are useful as herbicides and can be formulated to provide herbicidal compositions.
    Type: Grant
    Filed: October 14, 1975
    Date of Patent: June 7, 1977
    Assignee: The Dow Chemical Company
    Inventor: Alin H. Gulbenk
  • Patent number: 4027010
    Abstract: Antistaphylococcous human immunoglobulin consisting of gamma globulin fraction isolated from the plasma of man immunized with staphylococcous toxoid, containing staphylococcous .alpha.-antitoxin in the titre from 50 to 640 Units per ml and agglutinins against staphylococci in the titre to 1:20480 in a physiological or isotonic solution.The method for preparing said antistaphyloccus human immunoglobulin consists in that the plasma isolated from the blood of donors immunized with staphylococcus toxoid in the doses of 1, 1 and 2 ml, injected at 7-day intervals, is fractionated with ethyl alcohol at subzero temperatures with subsequent isolation of the gamma globulin fraction, its purification, drying and dissolution in physiological or isotonic solution. This immunoglobulin is useful in treating staphylococcal infections.
    Type: Grant
    Filed: April 15, 1975
    Date of Patent: May 31, 1977
    Inventors: Anatoly Efimovich Kiselev, Semen Vladimirovich Skurkovich, Tatyana Vasilievna Golosova, Anatoly Alexandrovich From, Grigory Fedoseevich Papko, Ljudmila Semenovna Shenkman, Tatyana Pavlovna Anikina
  • Patent number: 4024333
    Abstract: A method for synthesizing daunosamine hydrochloride from methyl .alpha.-D-mannopyranoside. The major features of the preparative route involve the formation of a 2-deoxy-3-keto intermediate, whose oxime is reduced with high stereoselectivity to the D-ribo-3-amino compound, followed by a stereospecific step late in the sequence to introduce the terminal C-methyl group with inversion at C-5, to generate the required L-lyxo stereochemistry. The synthesis procedure affords daunosamine hydrochloride in 40% overall yield, with no chromatographic procedures for isolation being required in any of the steps.
    Type: Grant
    Filed: June 22, 1976
    Date of Patent: May 17, 1977
    Assignee: The United States of America as represented by the Department of Health, Education and Welfare
    Inventors: Derek Horton, Wolfgang F. Weckerle