Patents Examined by Lewis Gotts
  • Process for the manufacture of insulin, analogs and derivatives thereof
    Patent number: 4014861
    Abstract: A process for manufacture of insulin, analogs and derivatives thereof by treating an insulin compound wherein the A- and B-chains are linked by a bis-methionyl-carbonyl-bridge, with cyano bromide.
    Type: Grant
    Filed: June 10, 1975
    Date of Patent: March 29, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rolf Geiger, Rainer Obermeier
  • Water treatment for controlling the growth of algae employing biguanides
    Patent number: 4014676
    Abstract: A method of controlling the growth of bacteria and algae in the water of swimming pools by adding to the water a specified concentration of a polymeric biguanide. Has the advantage over chlorination that at the low concentration employed the polymeric biguanide is non-toxic, non-irritant, tasteless and odorless. The anti-bacterial and anti-algal effect is also highly persistent.
    Type: Grant
    Filed: December 17, 1973
    Date of Patent: March 29, 1977
    Assignee: Imperial Chemical Industries Limited
    Inventors: Graham Carter, Anthony John Hinton
  • Process for preparing cyclicdicarboximido-substituted phosphonothioates
    Patent number: 4014897
    Abstract: Cyclicdicarboximido-substituted phosphonothioates corresponding to the formula ##EQU1## WHEREIN R represents phthalimido, monomethyl substituted phthalimido, 4-cyclohexene-1,2-dicarboximido or monomethyl substituted 4-cyclohexene-1,2,-dicarboximido are prepared by a method which comprises reacting an appropriate O,O-diloweralkyl phosphorochloridothioate with an appropriate N-alkali metal cyclicdicarboximide reactant in the presence of a catalytic amount of a 1-(loweralkyl)imidazole and an inert tertiary alcohol as a reaction medium.
    Type: Grant
    Filed: October 7, 1974
    Date of Patent: March 29, 1977
    Assignee: The Dow Chemical Company
    Inventor: Ian McLachlan
  • Production of amines from alcohols
    Patent number: 4014933
    Abstract: An improved method of preparing amines by reaction of alcohols with ammonia or primary or secondary amines at elevated temperature and superatmospheric pressure in the presence of hydrogen and a hydrogenation catalyst containing cobalt, nickel and copper, the improvement comprising using a catalyst which contains (calculated on the metal content of the catalyst) from 70 to 95% by weight of a mixture of cobalt and nickel and from 5 to 30% by weight of copper, the ratio by weight of cobalt to nickel being from 4:1 to 1:4. The amines prepared in this way are suitable for the production of emulsifying agents, plant protection agents and vulcanization accelerators.
    Type: Grant
    Filed: August 27, 1973
    Date of Patent: March 29, 1977
    Assignee: BASF Aktiengesellschaft
    Inventors: Guenther Boettger, Hubert Corr, Herwig Hoffmann, Herbert Toussaint, Siegfried Winderl
  • Lubricant additive
    Patent number: 4014803
    Abstract: Novel compounds, which are useful as additives in lubricating oils, are disclosed. The novel compounds are represented by the formula ##STR1## wherein R is an alkenyl group containing 10 to 100 carbon atoms; R' is an alkylene group containing 1 to 5 carbon atoms; n is an integer of 1 to 4; X is selected from the group consisting of NH.sub.2, NR"R", NHR", and OR"; and Y is selected from the group consisting of NR"R", NHR", OR", and halogen, wherein R" is alkyl, phenyl, alkyl-substituted phenyl, or alkylene polyamino. A process for preparing the novel compounds is disclosed, also.
    Type: Grant
    Filed: August 25, 1975
    Date of Patent: March 29, 1977
    Assignee: Continental Oil Company
    Inventor: Hugh E. Romine
  • Aminomethylenemalonitriles
    Patent number: 4014917
    Abstract: Compounds of formula ##STR1## wherein R is substituted- or unsubstituted- aryl, alkyl, aralkyl or heterocyclic linked via a carbon atom in the heterocycle and Z is trichloromethylthio, dichlorofluoromethylthio, ##STR2## where R' is substituted- or unsubstituted- alkyl, aryl or aralkyl, are fungicides, especially for combating fungal diseases of plants eg vines.
    Type: Grant
    Filed: October 3, 1973
    Date of Patent: March 29, 1977
    Assignee: Fisons Limited
    Inventor: Peter Laurence Carter
  • Manufacture of 4,4'-diphenylmethane diisocyanate and a mixture of diisocyanates and polyisocyanates
    Patent number: 4014914
    Abstract: Production of 4,4'-diphenylmethane diisocyanate and a mixture of diisocyanates and polyisocyanates by the phosgenation of pure 4,4'-diaminodiphenylmethane and a mixture of diamines and polyamines. 4,4'-Diaminodiphenylmethane is obtained by distillation of the mixture of products obtained from the reaction of aniline with formaldehyde and crystallization of the distillate from a solvent. The combined distillation residue and mother liquor from the crystallization form the mixture for reaction with phosgene to produce a mixture of diisocyanates and polyiisocyanates. This process produces a highly pure 4,4'-diphenylmethane diisocyanate which is particularly suitable for the production of polyurethanes serving as intermediates in the manufacture of rigid foams or as glue.
    Type: Grant
    Filed: October 25, 1974
    Date of Patent: March 29, 1977
    Assignee: Badische Anilin- & Soda-Fabrik Aktiengesellschaft
    Inventors: Hans Joachim Pistor, Herwig Hoffmann, Hans-Ingo Joschek, Gotthilf Wenner
  • Synthesis of a dithiol from 1-methyl-2-(2-hydroxyethylthio)-4-[1-methyl-2-(2-hydroxyethylthio)ethyl] cyclohexane
    Patent number: 4013724
    Abstract: The synthesis of a new diol compound by the reaction of 2-mercaptoethanol and d,1-limonene to produce the diol 1-methyl-2-(2-hydroxyethylthio)-4[1-methyl-2-(2-hydroxyethylthio)ethyl]cyc lohexane. The diol can be used as an intermediate in a reaction with a thiourea for the synthesis of a new dithiol, 1-methyl-2-(2-mercaptoethylthio)-4-[1-methyl-2-(2-mercaptoethylthio)-ethyl ]cyclohexane.
    Type: Grant
    Filed: July 24, 1975
    Date of Patent: March 22, 1977
    Assignee: Phillips Petroleum Company
    Inventor: Paul F. Warner
  • 2,5-Diisopropylterephthalonitrile
    Patent number: 4013704
    Abstract: 2,5-Diisopropylterephthalonitrile is a selective herbicide.
    Type: Grant
    Filed: May 2, 1975
    Date of Patent: March 22, 1977
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: Elmore Louis Martin
  • Process for the purification of polycarbonates
    Patent number: 4013702
    Abstract: The free and bonded residual phenol content of oligocarbonates prepared by transesterification between a diol and a diphenyl carbonate is substantially reduced by a process comprising (i) introducing water into the oligocarbonate in the liquid state at an elevated temperature under reduced pressure and (ii) purging the mixture with an inert gas to effect degassing. The purified oligocarbonates are particularly resistant to yellowing.
    Type: Grant
    Filed: December 4, 1975
    Date of Patent: March 22, 1977
    Assignee: Societe Nationale des Poudres et Explosifs
    Inventors: Jean-Pierre L. Cartier, Jean-Pierre G. Senet
  • Inhibiting grass growth with 5-acetamido-2,4-dimethyltrifluoromethanesulfonanilide
    Patent number: 4013444
    Abstract: 5-Acetamido-2,4-dimethyltrifluoromethanesulfonanilide. This compound is a plant growth regulator.
    Type: Grant
    Filed: June 19, 1975
    Date of Patent: March 22, 1977
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Tomas L. Fridinger
  • Herbicidal compositions for killing weeds in vineyards
    Patent number: 4013451
    Abstract: A composition for selective weed control in vineyards and orchards containing as active material at least one of the following compounds: ##STR1##
    Type: Grant
    Filed: September 5, 1975
    Date of Patent: March 22, 1977
    Assignee: Philagro S.A.
    Inventors: Pierre Poignant, Guy Borrod, Raymond Richard
  • Process for the preparation of insulin, analogs and derivatives thereof
    Patent number: 4013628
    Abstract: A process for the manufacture of insulin and derivatives thereof by treating an insulin derivative, wherein the A-chain is cross-linked with the B-chain by means of a sulfonyl diethyl-bisoxycarbonyl bridge and the B-chain may contain an acyl group in the 1-position, with alkali metal hydroxides or quaternary organic bases having a pH value of more than 13.
    Type: Grant
    Filed: August 14, 1975
    Date of Patent: March 22, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Rainer Obermeier, Rolf Geiger
  • Arylchalcogeno-substituted aliphatic acids and esters
    Patent number: 4013708
    Abstract: New compounds of the general formula Ir.sub.1 -- ph -- X -- CR.sub.2 R.sub.4 -- alk -- R.sub.3 (I)wherein R.sub.1 denotes a cycloalkenyl radical or a monocyclic cycloalkyl radical, Ph denotes an optionally substituted phenylene radical, X denotes the oxy or thio group, R.sub.2 denotes hydrogen or alkyl, R.sub.3 denotes an optionally functionally modified carboxyl group, a sulpho group or a sulphamido group, alk denotes an alkylene or alkenylene radical which separates the groups R.sub.1 --Ph--X--CR.sub.2 R.sub.4 and R.sub.3 by at least 2 carbon atoms and R.sub.4 is hydrogen or, if alk separates the groups R.sub.1 --Ph--X--CR.sub.2 R.sub.4 and R.sub.3 by at least 3 carbon atoms or R.sub.1 denotes a cycloalkenyl radical, R.sub.4 can also denote alkyl, in the free form or in the form of salts are useful as antiallergics.
    Type: Grant
    Filed: September 11, 1974
    Date of Patent: March 22, 1977
    Assignee: Ciba-Geigy Corporation
    Inventors: Georges Haas, Pier Giorgio Ferrini, Alberto Rossi
  • 1-(Bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid derivatives, their production and their use as plant-growth regulators and herbicides
    Patent number: 4013445
    Abstract: The present invention relates to new 1-(bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid derivatives, to processes for their production, to compositions containing these active substances, as well as to the use of these active substances and compositions for the regulation of plant growth and as herbicides.These derivatives correspond to formula I ##STR1## wherein A represents the nitrile or carboxylic acid group or a derivative of the carboxylic acid.
    Type: Grant
    Filed: October 23, 1975
    Date of Patent: March 22, 1977
    Assignee: Ciba-Geigy Corporation
    Inventors: Daniel Bellus, Werner Fory
  • Process for the simultaneous manufacture of epsilon-caprolactones and carboxylic acids
    Patent number: 4013691
    Abstract: A cyclohexanone is oxidized by molecular oxygen in the presence of an aldehyde, a soluble compound of a metal selected from the group consisting of iron, palladium, vanadium, chromium, molybdenum, tungsten and cerium, and a compound which has a heterocyclic ring containing at least one nitrogen atom and which acts as a multidantate ligand, to form an epsilon-caprolactone and a carboxylic acid corresponding to the aldehyde.
    Type: Grant
    Filed: October 8, 1975
    Date of Patent: March 22, 1977
    Assignee: Mitsubishi Chemical Industries Ltd.
    Inventors: Takao Maki, Kazuyuki Mineta
  • Process for the preparation of diaryl carbonates
    Patent number: 4012406
    Abstract: A process for the preparation of a diaryl carbonate by the reaction of an aromatic monohydroxy compound with phosgene under elimination of hydrogen chloride, wherein said reaction is carried out in the presence of a catalytic quantity of an aromatic heterocyclic basic nitrogen compound, or a salt thereof, or an adduct thereof formed under the reaction conditions.
    Type: Grant
    Filed: September 30, 1975
    Date of Patent: March 15, 1977
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans Josef Buysch, Heinrich Krimm
  • Sulphur compounds
    Patent number: 4012331
    Abstract: A process for the preparation of a sulphur compound suitable for use as a lubricant additive comprises reacting a trithiolan compound with a thiol compound in the presence of a base.
    Type: Grant
    Filed: July 21, 1975
    Date of Patent: March 15, 1977
    Assignee: Edwin Cooper and Company Limited
    Inventors: Gerald John Joseph Jayne, Herbert Frank Askew, David Robert Woods
  • Process for the separation of 4,4'-dichlorodiphenylsulfone
    Patent number: 4012451
    Abstract: Pure 4,4'-dichlorodiphenylsulfone is separated from the reaction mixture containing 4,4'-dichlorodiphenylsulfone and the isomers thereof by adding the reaction mixture to the mixture of trichloroethylene or tetrachloroethylene, and water to extract 4,4'-dichlorodiphenylsulfone with said organic solvent and cooling the organic solution separated from the water layer to precipitate pure 4,4'-dichlorodiphenylsulfone.
    Type: Grant
    Filed: January 19, 1976
    Date of Patent: March 15, 1977
    Assignee: Nippon Soda Company Limited
    Inventors: Kichiji Enoki, Takeo Fukui, Takeo Yamamoto, Toshirou Okada, Yoshiaki Miyazaki
  • Herbicidal 4-pyrimidinones and pyrimidinethiones
    Patent number: 4012388
    Abstract: A class of new 4-pyrimidinones and thiones have a small alkyl group at the 1-position and a substituted phenyl group at the 5-position. The compounds are herbicides.
    Type: Grant
    Filed: December 11, 1975
    Date of Patent: March 15, 1977
    Assignee: Eli Lilly and Company
    Inventors: James Richard Beck, Robert Peter Gajewski