Abstract: Bicyclic heterocyclyl containing N-(bicyclic heterocyclyl)-4-piperidinamines having antihistaminic and serotonin-antagonistic properties which compounds are useful agents in the treatment of allergic diseases.

Abstract: A new diphenyl-methane derivative is useful to inhibit agglomeration of blood and is defined by the formula, including a diphenylethylene derivative and a benzophenone oxime ether derivative. ##STR1## in which R1 and R2 each are hydrogen, hydroxyl or a lower alkoxy, U is .dbd.CXY or .dbd.N--O--W,X is hydrogen, cyano or --COR6, R6 being hydroxyl or an amino, Y is --R10--COOR3, R3 being hydrogen or a lower alkoxy, R10 being an alkylene having 1 to 3 carbon atoms, straight or branched, --CO--NR4R5, R4 and R5 each being hydrogen, a lower alkyl or a lower arylalkyl, --CH2--NHSO2--C6H5 or --C(R8).dbd.NR7, R7 being a lower alkoxy or an aryl, R8 is --VR9, V being oxygen, sulfur or nitrogen, R9 being an alkyl or an aryl,W is --CH2--CO--CH2--COOR13, R13 being hydrogen or a lower alkyl, --CH2--C(C.dbd.

Abstract: A method of fighting fungus infections by using compounds having the formula: ##STR1## wherein: R is H, a C.sub.1 -C.sub.4 alkyl, an alkenyl, or an alkynyl radical; n is 1 or 2;A represents a C.sub.1 -C.sub.6 alkylene bridge, an arylene or a heterocyclic bridge;X represents O, S, SO, SO.sub.2 ; andR.sup.1 is selected from the group consisting of C.sub.1 -C.sub.6 alkyl radicals, a phenyl radical, optionally substituted, polyfluoroalkyl radicals containing from 1 to 4 carbon atoms and at least 2 fluorine atoms, polyfluoroalkenyl radicals containing from 2 to 4 carbon atoms and at least 2 fluorine atoms, but excluding compounds having the formula (I) wherein A is an alkylene radical, n is 2, and R.sup.1 is a C.sub.1 -C.sub.6 alkyl radical.

Abstract: Novel 2- or 3- aryl substituted imidazo[1,2-a]pyridines and their synthesis are described. The compounds have local anesthetic properties and are useful as local anesthetic agents, calcium channel blocking agents and antisecretory agents.

Abstract: A hydraulic braking system for an automotive vehicle having a hydraulic braking pressure generator arranged to control the communication of a pressure chamber defined therein with a power source and a reservoir in response to depression of a brake pedal. The power chamber is normally communicated with the reservoir through a drain passage when the brake pedal is not depressed. Between the pressure generator and wheel brake cylinders disposed is valve means for controlling the communication of the wheel brake cylinders with the pressure generator and the reservoir. A changeover valve is arranged to normally communicate the power chamber with the reservoir and communicate the power chamber with the power source through the drain passage blocking its communication with the reservoir in a slip condition of driven wheels. In accelerating operation the changeover valve and the valve means are operated depending on the slip condition of the driven wheels to brake the same effectively preventing the slip.

Abstract: An overspeed brake mounted on an elevator cage includes a shaft that carries a pinion engageable with a rack so that linear movement of the cage produces rotation of the shaft. A carrier rotated by the shaft has two pivotably mounted dogs thereon that move outwardly at a predetermined centrifugal force level to cause rotation of a separation ring. A spreader causes axial first separation between the first ring and a second separation ring in response to the rotation, forcing two brake surfaces together and stopping rotation of the shaft, thereby halting linear motion of the cage.

Abstract: This disclosure relates to a class of novel substituted alkylidene imidazole derivatives and pharmaceutically acceptable salts thereof. The disclosure further describes pharmaceutical compositions containing such compounds and to the use of such compounds and compositions as agents for selectively inhibiting the action of the enzyme thromboxane synthetase.

Abstract: An electrostatographic printing system is disclosed as having a sheet registration mechanism comprising rotating fingers arranged to intercept the leading edges of copy sheets and to register the same as they are being processed. The fingers are mounted in flexible joints so that they may be flexed out of operation in the event that extra large copy sheets are being processed.

Abstract: The device comprises a conveyor (A) driven with a reciprocating movement by means of a jack (V1) and on which the object (T) is placed in any way, wherein a stationary stop (CO), located crosswise with respect to said movement, acts as a deviating means as the object comes into contact with it. The device is completed with a vertically movable parts (BP), which almost comes into flush relationship with the upper part of the object so as to abviate any distortion in the plane (FIG. 3).

Abstract: Novel 5-halopyridine-3-carboxamide compounds having the general formula (I) ##STR1## or salts thereof wherein R is hydrogen atom or a group of --(CH.sub.2).sub.n --R.sub.1 wherein n is an integer from 1 to 4 and R.sub.1 is hydrogen atom, hydroxy group, lower alkoxy group, mercapto group, lower alkylthio group, amino group, di-lower alkylamino group, C.sub.1-11 alkyl group, lower alkenyl group, lower alkynyl group, cycloalkyl group, 5- or 6-membered heterocyclic group or aryl group which may be substituted by one or two substituents of halogen, lower alkyl or lower alkoxy;R.sub.2 and R.sub.3 are, the same of different, hydrogen atom, halogen atom, cyano group, nitro group, amino group, lower akyl group, halogenated lower alkyl group, hydroxy group, lower alkoxy group, aryloxy group, carboxy group or lower alkoxycarbonyl group;X is halogen atom; which compounds possess growth inhibitory activities and also anti-inflammatory activity.

Abstract: Novel circulation active dihydropyridines of the formula ##STR1## in which X is CO, SO.sub.2 or CONH,R.sup.4 is H, OH, alkyl, halogen, acyloxy, alkoxyalkoxy, aralkyloxy, or together with R.sup.5 forms a heterocyclic ring, andthe other radicals are conventional in the dihydropyridine art,and pharmaceutically acceptable salts thereof.

Abstract: Compounds are provided of the following general structure: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are independently selected from hydrogen or methyl; A is amino, C.sub.1 -C.sub.4 monoalkylamino, C.sub.2 -C.sub.8 dialkylamino, 1-pyrrolidinyl, 1-piperidinyl, 4-morpholinyl or cyclopropylamino; and where W and Q are independently selected from 2-pyridinyl, 3-pyridinyl or 4-pyridinly or phenyl, provided W and Q are not both phenyl.

Abstract: This invention relates to highly attrition resistant catalysts, catalyst precursors and catalyst supports and to processes for making and using them.

Abstract: 3-Hydroxyazabenzo[b]thiophene derivatives having optionally 2-aryl, 2-aralkyl, 2-alkyl or 2-alkenyl substituents were prepared by, among other methods, ring closure of an appropriately substituted benzylthio-alkoxycarbonyl-pyridine. These compounds are found to be useful in the treatment of pain, fever, inflammation, arthritic conditions, asthma, allergic disorders, skin diseases such as psoriasis and atopic eczema, cardiovascular disorders, inflammatory diseases and other leukotriene mediated diseases.

Abstract: Compounds of the formula ##STR1## are disclosed wherein the variables are herein described. These compounds are intermediates to compounds which influence the influx of calcium into the cell.

Abstract: A brake system for a drawworks includes a hydraulically actuated band brake system having a backup spring actuator for emergency stops. The system also includes a caliper disc brake system for emergency stops. The disc brake system includes a rotor directly mounted to the drum barrel and a pair of spring actuated caliper assemblies.

Abstract: A dynamic sealing ring made of a resilient flowable material such as an elastomer throughout, characterized by its cross-sectional configuration which in its free form is uniform and generally rectangular with arcuate smoothly contoured convex lobes at each of its corners, with its two opposed axially extending surfaces bearing additional annular convex sealing lobes in unequal numbers disposed in non-opposite relation between the adjacent corner lobes and separated therefrom and from each other by concavities and extending outwardly therebeyond a short distance to effect a more perfect seal, particularly when applied in encircling relation to a reciprocating piston rod and subjected to high gaseous pressures from a single direction or as a piston seal.

Abstract: A vehicle suspension damper with remote control includes a fluid controller operatively connected to the damper. The piston assembly of the damper includes a valve driven by a fluid motor receiving pressure signals from the controller.

Abstract: A braked twin-wheel caster assembly consists of five components--a body, two indentical wheels, a metal wheel spindle and a locking lever. A molded brake lever, rockable between a wheel-locking position and an unlocking position in which the wheels are free to turn, has an intermediate mounting portion which pivots in a bearing recess in the moulded body. The bearing recess is disposed towards the trailing end of the body, and it is open at an outer aperture and also at an inner aperture. An outer end portion of the locking lever projects through the outer aperture to provide an operating member for external operation. An inner end portion of the locking lever projects from said inner aperture to provide a locking member for engagement with the caster wheels. The intermediate portion of the locking lever is molded so that it can be resiliently compressed sufficiently for it to be inserted into the bearing recess through the outer aperture.

Abstract: A sheet aligning device including a pair of side walls located parallel to each other and defining therebetween a space for stacking a plurality of sheets. At least one of the side walls is movable in reciprocatory movement widthwise of the sheets stacked between the side walls to force the sheets against the other side wall so as to align the sheets widthwise thereof which is perpendicular to the direction in which they are delivered. The sheet aligning device includes at least one sensor for sensing the magnitudes of displacements of the sheets widthwise thereof and producing an output for adjusting at least one of the frequency, speed and stroke of the reciprocatory movement of the at least one side wall in accordance with the magnitudes of the displacements.