Abstract: Acetic acid derivatives having the formula, ##STR1## wherein X represents an oxygen or two hydrogen atoms, Y represents CH or N, A represents an oxygen or sulfur atom, and R represents hydroxy, amino or a lower alkoxy group having 1 to 5 carbon atoms possess excellent antiinflammatory activities.
Abstract: There are provided compounds of the formula: ##STR1## wherein R is an adamantyl group, or a phenyl group unsubstituted or substituted with a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a halogen atom, a nitro group, a cyano group, a methylenedioxy group or an acetamido group, useful as anti-transplanted-tumor agents and immunosuppressants.
Abstract: Dyestuffs of the formula ##STR1## wherein R.sup.1, R.sup.2, R denote H, alkyl, alkenyl, cycloalkyl, aralkyl etc.R.sup.3, R.sup.4 denote H, alkyl, aralkyl, aryl, alkoxy, halogen, CN, COOH, alkoxycarbonyl, alkylsulfonyl, arylsulfonyl etc.Z denotes O, S or --N(R)--,p and q denote 0 or 1, but not simultaneously 0 andG stands for the remaining members of a ring system,with the proviso that R.sub.3 is not alkyl if G is a thiazole ring, are outstanding suitable for dyeing fibre materials of all kinds in clear yellow to violet shades with good fastness properties.
Abstract: Neuroleptically active octahydro-1H-pyrrolo[2,3-g]isoquinolines of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and X are as hereinafter set forth,are described.
Abstract: New and valuable pyrazole derivatives having a good herbicidal action, herbicides containing these compounds as active ingredients, and processes for controlling the growth of unwanted plants with these compounds.
Type:
Grant
Filed:
October 16, 1978
Date of Patent:
April 7, 1981
Assignee:
BASF Aktiengesellschaft
Inventors:
Peter Plath, Bruno Wuerzer, Wolfgang Rohr
Abstract: The present invention is concerned with novel tricyclic sulphoximides and with the preparation thereof. This family of compounds has been found to possess antihistaminic, antitussive, antiinflammatory, sedative, and diuretic properties.
Type:
Grant
Filed:
October 11, 1979
Date of Patent:
March 31, 1981
Assignee:
Warner-Lambert Company
Inventors:
Peter Stoss, Gerhard Satzinger, Manfred Herrmann
Abstract: Novel 2-(Imidazol-1-ylmethyl)pyrroles and pharmaceutically acceptable acid addition salts thereof are disclosed. The novel compounds are useful in selectively inhibiting the action of the thromboxane synthetase enzyme.
Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are hydrogen or substituents of various types;R.sub.4 is hydrogen; alkyl of 1 to 5 carbon atoms; or optionally substituted aralkyl of 7 to 14 carbon atoms;R.sub.5 is a heterocycle;D is alkylene of 1 to 12 carbon atoms; andA is hydrogen or acyl;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as .alpha.- and .beta.-adrenergic receptor blocking agents and antidepressants.
Type:
Grant
Filed:
January 17, 1979
Date of Patent:
March 17, 1981
Assignee:
Boehringer Ingelheim GmbH
Inventors:
Herbert Koppe, Anton Mentrup, Ernst-Otto Renth, Kurt Schromm, Wolfgang Hoefke, Gojko Muacevic
Abstract: Phosphoric or thiophosphoric esters of 5(3)-hydroxypyrazoles are disclosed having the formula: ##STR1## wherein: R=H; alkyl with 1-7 carbon atoms optionally substituted with halogens, CN, and carboalkoxy groups; phenyl optionally substituted; benzyl; alkenyl; or alkynyl;X=halogen; --SR; --OR; --N(R).sub.2 ; or ##STR2## where Y is equal to or different from each other, and=H; C.sub.1 -C.sub.3 alkyl; halogen; --SR; --OR; or --N(R).sub.2 ;Z=S; or O; andR.sup.1 and R.sup.2, equal to or different from each other, are: alkoxyls; alkyls; phenyls; or alkylthio- or alkyl-amino-groups.These are useful as insecticides, acaricides and nematodacides.Also disclosed are 5(3)-hydroxypyrazoles having the formula: ##STR3## wherein: R=H; alkyl with 1-7 carbon atoms, optionally substituted with halogen atoms, CN, and carboalkoxy-groups; phenyl optionally substituted; benzyl; alkenyl; or alkynyl;X=halogen; --SR; --OR; --N(R).sub.2 ; or ##STR4## where Y is equal to or different from each other, and =H; C.sub.1 -C.sub.
Type:
Grant
Filed:
March 12, 1980
Date of Patent:
March 17, 1981
Assignee:
Montedison S.p.A.
Inventors:
Pier M. Boschi, Franco Gozzo, Angelo Longoni
Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each hydrogen or a substituent of various types;R.sub.4 is hydrogen, alkyl of 1 to 5 carbon atoms, or optionally substituted aralkyl of 7 to 14 carbon atoms;R.sub.5 is a heterocycle;D is a alkylene of 1 to 12 carbon atoms; andA is hydrogen or acyl,and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as .alpha.- and .beta.-adrenergic receptor blocking agents and antidepressants.
Type:
Grant
Filed:
December 14, 1979
Date of Patent:
March 10, 1981
Assignee:
Boehringer Ingelheim GmbH
Inventors:
Herbert Koppe, Anton Mentrup, Ernst-Otto Renth, Kurt Schromm, Wolfgang Hoefke, Gojko Muacevic
Abstract: The present invention concerns pyridyloxy-phenoxy-alkanecarboxylic acid derivatives of the formula ##STR1## wherein A is hydrogen, halogen, alkyl, alkoxy, cyano, nitro or carbothiamideB is hydrogen, halogen, alkyl, cyano, mono- or dialkylamino, alkoxy-carbonyl or carbothiamideC is hydrogen, halogen, cyano, nitro or carbothiamideD is hydrogen, halogen, alkyl, mono- or dialkylaminoR.sub.1 is hydrogen, alkyl, alkoxyalkyl or benzylR is the rest of the acid a salt or an ester,with the proviso that if the pyridine ring is substituted by halogen and/or alkyl and C is also halogen, then the radicals A, B and D must contain no less than two halogen atoms or alkyl radicals.These derivatives have herbicidal and plant-growth regulating activity.
Abstract: Novel heterocyclic compounds shown by the formula ##STR1## wherein Het represents a 5-membered or 6-membered heterocyclic group which may have substituent(s); Z represents a sulfur atom or oxygen atom; X represents an oxygen atom or the unsubstituted or substituted imino group shown by N--R.sub.1 (wherein R.sub.
Abstract: Compounds of the formula ##STR1## wherein R.sup.1, R.sub.2 and R.sub.3 denote hydrogen, chlorine or methyl,R.sup.4 denotes C.sub.1 -C.sub.4 -alkyl which is optionally substituted by phenyl, hydroxyl or C.sub.1 -C.sub.4 -alkoxy andX.sup..crclbar. denotes a colorless anion.A process for their preparation and processes for brightening polyacrylonitrile and wool using compounds of the formula (I).
Type:
Grant
Filed:
December 7, 1978
Date of Patent:
February 24, 1981
Assignee:
Bayer Aktiengesellschaft
Inventors:
Carl-Wolfgang Schellhammer, Bernhard Wehling
Abstract: 2-Substituted-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles of the formula (I): ##STR1## and the pharmaceutically-acceptable salts thereof, wherein the hydrogen atoms in the 4a position and 9b positions are in a trans relationship to each other and the 5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole moiety is dextrorotatory; X.sub.1 and Y.sub.1 are the same or different and are each hydrogen or fluoro; Z.sub.1 is hydrogen, fluoro or methoxy; M is a member selected from the group consisting of ##STR2## a mixture thereof and C=0 and n is 3 or 4; their use as tranquilizing agents, pharmaceutical compositions containing them and a process for their production.
Abstract: Certain 1-(3,5-dichlorobenzoyl)-3-phenylpyrazolines which have the structural formula ##STR1## where R is hydrogen, alkyl, alkoxy or halo and their uses as a mildewicide.
Abstract: Novel benzofuranyl benzimidazoles of the formula ##STR1## wherein R.sub.1 represents a hydrogen atom, an alkenyloxy or cycloalkloxy radical, an unsubstituted or substituted alkoxy, phenylalkoxy or phenoxy radical, each ofR.sub.2 and R.sub.3 independently represents a hydrogen atom, an alkyl or alkoxy radical, a halogen atom, or, if R.sub.1 represents hydrogen, together in the ortho-position to each other they represent a radical of the formula --CH.dbd.CH--CH.dbd.CH--, --O--CH.sub.2 --O-- or --O--CH.sub.2 --CH.sub.2 --O--,R.sub.4 represents a hydrogen atom, an alkyl, alkoxy or phenyl radical,R.sub.5 represents a sulpho or carboxyl group or the functional derivatives thereof including the cyano group or the trifluoromethyl group,R.sub.6 represents a hydrogen or halogen atom, an alkyl or alkoxy radical,R.sub.7 represents a cycloalkyl, alkenyl, or unsubstituted or substituted alkyl, phenyl or phenylalkyl radical, or, if n is O, also represents a hydrogen atom,R.sub.
Abstract: Ethylenically unsaturated crosslinking agents and polymerizable monomers are disclosed. These agents contain a heterocyclic nucleus and are capable of forming oxygen insensitive, radiation curable systems.
Type:
Grant
Filed:
June 25, 1979
Date of Patent:
February 3, 1981
Assignee:
Minnesota Mining and Manufacturing Company
Abstract: Bis-(2,4-dinitrophenyl)-methylpyridinium compounds useful as a pH indicator or for the detection of ammonia having the formula: ##STR1## wherein one of R.sub.1 and R.sub.2 is a bis-(2,4-dinitrophenyl)-methyl radical and the other is a lower alkyl radical;R.sub.2 can also be hydrogen atom or trifluoromethyl;R.sub.3 and R.sub.4 are hydrogen or, together with the carbon atoms to which they are attached, represent a benzene ring; andX.sup..crclbar. is an appropriate acid anionor said compounds are betaines.
Type:
Grant
Filed:
April 30, 1979
Date of Patent:
January 13, 1981
Assignee:
Boehringer Mannheim GmbH
Inventors:
Anselm Rothe, Werner Guthlein, Walter Rittersdorf, Wolfgang Werner