Patents Examined by Natalia Harkaway
  • Patent number: 4263437
    Abstract: Acetic acid derivatives having the formula, ##STR1## wherein X represents an oxygen or two hydrogen atoms, Y represents CH or N, A represents an oxygen or sulfur atom, and R represents hydroxy, amino or a lower alkoxy group having 1 to 5 carbon atoms possess excellent antiinflammatory activities.
    Type: Grant
    Filed: February 27, 1979
    Date of Patent: April 21, 1981
    Assignee: Nippon Chemiphar Co., Ltd.
    Inventors: Yasuo Fujimoto, Shigeru Yamabe
  • Patent number: 4260774
    Abstract: There are provided compounds of the formula: ##STR1## wherein R is an adamantyl group, or a phenyl group unsubstituted or substituted with a lower alkyl group, a lower alkoxy group, a lower alkylthio group, a halogen atom, a nitro group, a cyano group, a methylenedioxy group or an acetamido group, useful as anti-transplanted-tumor agents and immunosuppressants.
    Type: Grant
    Filed: June 25, 1979
    Date of Patent: April 7, 1981
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Toshio Atsumi, Yoshiaki Takebayashi, Yuzo Tarumi, Hisao Yamamoto
  • Patent number: 4260776
    Abstract: Dyestuffs of the formula ##STR1## wherein R.sup.1, R.sup.2, R denote H, alkyl, alkenyl, cycloalkyl, aralkyl etc.R.sup.3, R.sup.4 denote H, alkyl, aralkyl, aryl, alkoxy, halogen, CN, COOH, alkoxycarbonyl, alkylsulfonyl, arylsulfonyl etc.Z denotes O, S or --N(R)--,p and q denote 0 or 1, but not simultaneously 0 andG stands for the remaining members of a ring system,with the proviso that R.sub.3 is not alkyl if G is a thiazole ring, are outstanding suitable for dyeing fibre materials of all kinds in clear yellow to violet shades with good fastness properties.
    Type: Grant
    Filed: January 23, 1979
    Date of Patent: April 7, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventor: Horst Harnisch
  • Patent number: 4260762
    Abstract: Neuroleptically active octahydro-1H-pyrrolo[2,3-g]isoquinolines of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4 and X are as hereinafter set forth,are described.
    Type: Grant
    Filed: September 10, 1979
    Date of Patent: April 7, 1981
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Leo Berger, Gary L. Olson
  • Patent number: 4260775
    Abstract: New and valuable pyrazole derivatives having a good herbicidal action, herbicides containing these compounds as active ingredients, and processes for controlling the growth of unwanted plants with these compounds.
    Type: Grant
    Filed: October 16, 1978
    Date of Patent: April 7, 1981
    Assignee: BASF Aktiengesellschaft
    Inventors: Peter Plath, Bruno Wuerzer, Wolfgang Rohr
  • Patent number: 4260767
    Abstract: 2-Pyridylhydrazides useful as antiinflammatory agents.
    Type: Grant
    Filed: December 26, 1979
    Date of Patent: April 7, 1981
    Assignee: American Cyanamid Company
    Inventor: John P. Dusza
  • Patent number: 4259494
    Abstract: The present invention is concerned with novel tricyclic sulphoximides and with the preparation thereof. This family of compounds has been found to possess antihistaminic, antitussive, antiinflammatory, sedative, and diuretic properties.
    Type: Grant
    Filed: October 11, 1979
    Date of Patent: March 31, 1981
    Assignee: Warner-Lambert Company
    Inventors: Peter Stoss, Gerhard Satzinger, Manfred Herrmann
  • Patent number: 4259345
    Abstract: Novel 2-(Imidazol-1-ylmethyl)pyrroles and pharmaceutically acceptable acid addition salts thereof are disclosed. The novel compounds are useful in selectively inhibiting the action of the thromboxane synthetase enzyme.
    Type: Grant
    Filed: February 21, 1980
    Date of Patent: March 31, 1981
    Assignee: Pfizer Inc.
    Inventors: Peter E. Cross, Roger P. Dickinson
  • Patent number: 4256756
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are hydrogen or substituents of various types;R.sub.4 is hydrogen; alkyl of 1 to 5 carbon atoms; or optionally substituted aralkyl of 7 to 14 carbon atoms;R.sub.5 is a heterocycle;D is alkylene of 1 to 12 carbon atoms; andA is hydrogen or acyl;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as .alpha.- and .beta.-adrenergic receptor blocking agents and antidepressants.
    Type: Grant
    Filed: January 17, 1979
    Date of Patent: March 17, 1981
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Herbert Koppe, Anton Mentrup, Ernst-Otto Renth, Kurt Schromm, Wolfgang Hoefke, Gojko Muacevic
  • Patent number: 4256902
    Abstract: Phosphoric or thiophosphoric esters of 5(3)-hydroxypyrazoles are disclosed having the formula: ##STR1## wherein: R=H; alkyl with 1-7 carbon atoms optionally substituted with halogens, CN, and carboalkoxy groups; phenyl optionally substituted; benzyl; alkenyl; or alkynyl;X=halogen; --SR; --OR; --N(R).sub.2 ; or ##STR2## where Y is equal to or different from each other, and=H; C.sub.1 -C.sub.3 alkyl; halogen; --SR; --OR; or --N(R).sub.2 ;Z=S; or O; andR.sup.1 and R.sup.2, equal to or different from each other, are: alkoxyls; alkyls; phenyls; or alkylthio- or alkyl-amino-groups.These are useful as insecticides, acaricides and nematodacides.Also disclosed are 5(3)-hydroxypyrazoles having the formula: ##STR3## wherein: R=H; alkyl with 1-7 carbon atoms, optionally substituted with halogen atoms, CN, and carboalkoxy-groups; phenyl optionally substituted; benzyl; alkenyl; or alkynyl;X=halogen; --SR; --OR; --N(R).sub.2 ; or ##STR4## where Y is equal to or different from each other, and =H; C.sub.1 -C.sub.
    Type: Grant
    Filed: March 12, 1980
    Date of Patent: March 17, 1981
    Assignee: Montedison S.p.A.
    Inventors: Pier M. Boschi, Franco Gozzo, Angelo Longoni
  • Patent number: 4255430
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each hydrogen or a substituent of various types;R.sub.4 is hydrogen, alkyl of 1 to 5 carbon atoms, or optionally substituted aralkyl of 7 to 14 carbon atoms;R.sub.5 is a heterocycle;D is a alkylene of 1 to 12 carbon atoms; andA is hydrogen or acyl,and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as .alpha.- and .beta.-adrenergic receptor blocking agents and antidepressants.
    Type: Grant
    Filed: December 14, 1979
    Date of Patent: March 10, 1981
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Herbert Koppe, Anton Mentrup, Ernst-Otto Renth, Kurt Schromm, Wolfgang Hoefke, Gojko Muacevic
  • Patent number: 4253866
    Abstract: The present invention concerns pyridyloxy-phenoxy-alkanecarboxylic acid derivatives of the formula ##STR1## wherein A is hydrogen, halogen, alkyl, alkoxy, cyano, nitro or carbothiamideB is hydrogen, halogen, alkyl, cyano, mono- or dialkylamino, alkoxy-carbonyl or carbothiamideC is hydrogen, halogen, cyano, nitro or carbothiamideD is hydrogen, halogen, alkyl, mono- or dialkylaminoR.sub.1 is hydrogen, alkyl, alkoxyalkyl or benzylR is the rest of the acid a salt or an ester,with the proviso that if the pyridine ring is substituted by halogen and/or alkyl and C is also halogen, then the radicals A, B and D must contain no less than two halogen atoms or alkyl radicals.These derivatives have herbicidal and plant-growth regulating activity.
    Type: Grant
    Filed: November 20, 1978
    Date of Patent: March 3, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Rolf Schurter, Hermann Rempfler
  • Patent number: 4252819
    Abstract: Novel heterocyclic compounds shown by the formula ##STR1## wherein Het represents a 5-membered or 6-membered heterocyclic group which may have substituent(s); Z represents a sulfur atom or oxygen atom; X represents an oxygen atom or the unsubstituted or substituted imino group shown by N--R.sub.1 (wherein R.sub.
    Type: Grant
    Filed: August 16, 1978
    Date of Patent: February 24, 1981
    Assignee: Yamanouchi Pharmaceutical Co., Ltd.
    Inventors: Yasufumi Hirata, Isao Yanagisawa, Toshinari Tamura, Masaaki Takeda
  • Patent number: 4252720
    Abstract: Compounds of the formula ##STR1## wherein R.sup.1, R.sub.2 and R.sub.3 denote hydrogen, chlorine or methyl,R.sup.4 denotes C.sub.1 -C.sub.4 -alkyl which is optionally substituted by phenyl, hydroxyl or C.sub.1 -C.sub.4 -alkoxy andX.sup..crclbar. denotes a colorless anion.A process for their preparation and processes for brightening polyacrylonitrile and wool using compounds of the formula (I).
    Type: Grant
    Filed: December 7, 1978
    Date of Patent: February 24, 1981
    Assignee: Bayer Aktiengesellschaft
    Inventors: Carl-Wolfgang Schellhammer, Bernhard Wehling
  • Patent number: 4252812
    Abstract: 2-Substituted-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles of the formula (I): ##STR1## and the pharmaceutically-acceptable salts thereof, wherein the hydrogen atoms in the 4a position and 9b positions are in a trans relationship to each other and the 5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indole moiety is dextrorotatory; X.sub.1 and Y.sub.1 are the same or different and are each hydrogen or fluoro; Z.sub.1 is hydrogen, fluoro or methoxy; M is a member selected from the group consisting of ##STR2## a mixture thereof and C=0 and n is 3 or 4; their use as tranquilizing agents, pharmaceutical compositions containing them and a process for their production.
    Type: Grant
    Filed: January 16, 1980
    Date of Patent: February 24, 1981
    Assignee: Pfizer Inc.
    Inventor: Willard M. Welch, Jr.
  • Patent number: 4250185
    Abstract: Certain 1-(3,5-dichlorobenzoyl)-3-phenylpyrazolines which have the structural formula ##STR1## where R is hydrogen, alkyl, alkoxy or halo and their uses as a mildewicide.
    Type: Grant
    Filed: March 10, 1980
    Date of Patent: February 10, 1981
    Assignee: Stauffer Chemical Company
    Inventor: Edmund J. Gaughan
  • Patent number: 4250317
    Abstract: Novel benzofuranyl benzimidazoles of the formula ##STR1## wherein R.sub.1 represents a hydrogen atom, an alkenyloxy or cycloalkloxy radical, an unsubstituted or substituted alkoxy, phenylalkoxy or phenoxy radical, each ofR.sub.2 and R.sub.3 independently represents a hydrogen atom, an alkyl or alkoxy radical, a halogen atom, or, if R.sub.1 represents hydrogen, together in the ortho-position to each other they represent a radical of the formula --CH.dbd.CH--CH.dbd.CH--, --O--CH.sub.2 --O-- or --O--CH.sub.2 --CH.sub.2 --O--,R.sub.4 represents a hydrogen atom, an alkyl, alkoxy or phenyl radical,R.sub.5 represents a sulpho or carboxyl group or the functional derivatives thereof including the cyano group or the trifluoromethyl group,R.sub.6 represents a hydrogen or halogen atom, an alkyl or alkoxy radical,R.sub.7 represents a cycloalkyl, alkenyl, or unsubstituted or substituted alkyl, phenyl or phenylalkyl radical, or, if n is O, also represents a hydrogen atom,R.sub.
    Type: Grant
    Filed: December 21, 1978
    Date of Patent: February 10, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Hans R. Meyer, Kurt Weber
  • Patent number: 4249011
    Abstract: Ethylenically unsaturated crosslinking agents and polymerizable monomers are disclosed. These agents contain a heterocyclic nucleus and are capable of forming oxygen insensitive, radiation curable systems.
    Type: Grant
    Filed: June 25, 1979
    Date of Patent: February 3, 1981
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Larry A. Wendling
  • Patent number: 4245096
    Abstract: Bis-(2,4-dinitrophenyl)-methylpyridinium compounds useful as a pH indicator or for the detection of ammonia having the formula: ##STR1## wherein one of R.sub.1 and R.sub.2 is a bis-(2,4-dinitrophenyl)-methyl radical and the other is a lower alkyl radical;R.sub.2 can also be hydrogen atom or trifluoromethyl;R.sub.3 and R.sub.4 are hydrogen or, together with the carbon atoms to which they are attached, represent a benzene ring; andX.sup..crclbar. is an appropriate acid anionor said compounds are betaines.
    Type: Grant
    Filed: April 30, 1979
    Date of Patent: January 13, 1981
    Assignee: Boehringer Mannheim GmbH
    Inventors: Anselm Rothe, Werner Guthlein, Walter Rittersdorf, Wolfgang Werner
  • Patent number: 4245106
    Abstract: This invention relates to a process for preparing pyrazole carboxylates having the formula ##STR1##
    Type: Grant
    Filed: July 5, 1979
    Date of Patent: January 13, 1981
    Assignee: Monsanto Company
    Inventors: Lawrence H. Brannigan, John E. Franz, Robert K. Howe